This menu provides the list of EV mRNAs identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
Filter datasets:
  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
Maximum false positive rate (FPR): Maximum true positive rate (TPR):
  - FPR is the probability that an absent mRNA accidently have higher intensity than that mRNA.
  - TPR is the percentile of mRNA among the present mRNAs.
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Since there are multiple primers in the microarray, the same mRNA can have several FPR and TPR values.

mRNA name UniProt accession FPR TPR Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
(FPR<0.05,TPR<0.5)
Metal transporter CNNM2 (Ancient conserved domain-containing protein 2) (Cyclin-M2)Q9H8M5 7.8e-16 2.7e-1Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nat Cell Biol. 2008 Dec;10(12):1470-6. doi: 10.1038/ncb1800. Epub 2008 Nov 16.		COG125312 / 0 / 12
Metal transporter CNNM2 (Ancient conserved domain-containing protein 2) (Cyclin-M2)Q9H8M5 8.5e-7 2.7e-1Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.		COG125312 / 0 / 12
Metal transporter CNNM3 (Ancient conserved domain-containing protein 3) (Cyclin-M3)Q8NE01 3.5e-9 1.3e-1Mesenchymal stem cell-derived microvesicles protect against acute tubular injury.
J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.		COG125312 / 0 / 12
Metal transporter CNNM3 (Ancient conserved domain-containing protein 3) (Cyclin-M3)Q8NE01 0.0e+0 4.6e-1Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells.
BMC Genomics. 2009 Nov 25;10:556. doi: 10.1186/1471-2164-10-556.		COG125312 / 0 / 12
Metal transporter CNNM2 (Ancient conserved domain-containing protein 2) (mACDP2) (Cyclin-M2)Q3TWN3 0.0e+0 3.9e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		COG125312 / 0 / 12
Metal transporter CNNM4 (Ancient conserved domain-containing protein 4) (mACDP4) (Cyclin-M4)Q69ZF7 0.0e+0 4.8e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		COG125312 / 0 / 12
Metal transporter CNNM3 (Ancient conserved domain-containing protein 3) (mACDP3) (Cyclin-M3)Q32NY4 1.8e-4 4.4e-1Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA.
PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.		COG125312 / 0 / 12
Metal transporter CNNM2 (Ancient conserved domain-containing protein 2) (Cyclin-M2)Q9H8M5 3.8e-2 5.7e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		COG125312 / 0 / 12
Metal transporter CNNM2 (Ancient conserved domain-containing protein 2) (Cyclin-M2)Q9H8M5 3.3e-2 5.7e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		COG125312 / 0 / 12
Metal transporter CNNM1 (Ancient conserved domain-containing protein 1) (Cyclin-M1)Q9NRU3 4.4e-2 3.3e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		COG125312 / 0 / 12
Metal transporter CNNM2 (Ancient conserved domain-containing protein 2) (Cyclin-M2)Q9H8M5 8.6e-3 6.2e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		COG125312 / 0 / 12
Metal transporter CNNM4 (Ancient conserved domain-containing protein 4) (Cyclin-M4)Q6P4Q7 3.8e-2 3.0e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		COG125312 / 0 / 12
Metal transporter CNNM1 (Ancient conserved domain-containing protein 1) (Cyclin-M1)Q9NRU3 3.9e-2 1.7e-1miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		COG125312 / 0 / 12
Metal transporter CNNM2 (Ancient conserved domain-containing protein 2) (Cyclin-M2)Q9H8M5 2.5e-2 9.3e-2miR-1289 and Zipcode-like Sequence Enrich mRNAs in Microvesicles.
Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.		COG125312 / 0 / 12
Metal transporter CNNM1 (Ancient conserved domain-containing protein 1) (Cyclin-M1)Q9NRU3 0.0e+0 1.9e-8Two distinct extracellular RNA signatures released by a single cell type identified by microarray and next-generation sequencing.
RNA Biol. 2016 Oct 28:0.		COG125312 / 0 / 12
Metal transporter CNNM1 (Ancient conserved domain-containing protein 1) (Cyclin-M1)Q9NRU3 0.0e+0 3.7e-1Two distinct extracellular RNA signatures released by a single cell type identified by microarray and next-generation sequencing.
RNA Biol. 2016 Oct 28:0.		COG125312 / 0 / 12
Metal transporter CNNM3 (Ancient conserved domain-containing protein 3) (Cyclin-M3)Q8NE01 0.0e+0 4.3e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		COG125312 / 0 / 12
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