This menu provides the list of EV mRNAs identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
Filter datasets:
  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
Maximum false positive rate (FPR): Maximum true positive rate (TPR):
  - FPR is the probability that an absent mRNA accidently have higher intensity than that mRNA.
  - TPR is the percentile of mRNA among the present mRNAs.
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The downloaded CSV file is not exactly the same as the displayed table. Opening CSV file with Excel can impair its content.

Since there are multiple primers in the microarray, the same mRNA can have several FPR and TPR values.

mRNA name UniProt accession FPR TPR Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
(FPR<0.05,TPR<0.5)
tRNA-splicing endonuclease subunit Sen2 (EC 3.1.27.9) (tRNA-intron endonuclease Sen2)Q6P7W5 5.9e-6 4.5e-1Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.		COG16769 / 0 / 9
tRNA-splicing endonuclease subunit Sen2 (EC 3.1.27.9) (tRNA-intron endonuclease Sen2)Q6P7W5 0.0e+0 3.4e-1Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation.
Biochem Biophys Res Commun. 2010 Aug 6;398(4):723-9. doi: 10.1016/j.bbrc.2010.07.008. Epub 2010 Jul 17.		COG16769 / 0 / 9
tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (Leukocyte receptor cluster member 5) (tRNA-intron endonuclease Sen34) (HsSen34)Q9BSV6 0.0e+0 4.3e-1First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.
Biol Cell. 2013 Jul;105(7):289-303. doi: 10.1111/boc.201200086. Epub 2013 May 4.		COG16769 / 0 / 9
tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (Leukocyte receptor cluster member 5) (tRNA-intron endonuclease Sen34) (HsSen34)Q9BSV6 0.0e+0 4.6e-1First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.
Biol Cell. 2013 Jul;105(7):289-303. doi: 10.1111/boc.201200086. Epub 2013 May 4.		COG16769 / 0 / 9
tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (Leukocyte receptor cluster member 5) (tRNA-intron endonuclease Sen34) (HsSen34)Q9BSV6 0.0e+0 4.6e-1First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.
Biol Cell. 2013 Jul;105(7):289-303. doi: 10.1111/boc.201200086. Epub 2013 May 4.		COG16769 / 0 / 9
tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (Leukocyte receptor cluster member 5) (tRNA-intron endonuclease Sen34) (HsSen34)Q9BSV6 0.0e+0 2.1e-1Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.
Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7312-7. doi: 10.1073/pnas.1220998110. Epub 2013 Apr 15.		COG16769 / 0 / 9
tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (Leukocyte receptor cluster member 5) (tRNA-intron endonuclease Sen34) (HsSen34)Q9BSV6 0.0e+0 2.0e-1Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.
Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7312-7. doi: 10.1073/pnas.1220998110. Epub 2013 Apr 15.		COG16769 / 0 / 9
tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (Leukocyte receptor cluster member 5) (tRNA-intron endonuclease Sen34) (HsSen34)Q9BSV6 0.0e+0 2.0e-1Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.
Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7312-7. doi: 10.1073/pnas.1220998110. Epub 2013 Apr 15.		COG16769 / 0 / 9
tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (Leukocyte receptor cluster member 5) (tRNA-intron endonuclease Sen34) (HsSen34)Q9BSV6 0.0e+0 2.1e-1Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development.
Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7312-7. doi: 10.1073/pnas.1220998110. Epub 2013 Apr 15.		COG16769 / 0 / 9
tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (Leukocyte receptor cluster member 5) (tRNA-intron endonuclease Sen34) (HsSen34)Q9BSV6 0.0e+0 3.7e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		COG16769 / 0 / 9
tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (Leukocyte receptor cluster member 5) (tRNA-intron endonuclease Sen34) (HsSen34)Q9BSV6 0.0e+0 6.9e-2The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		COG16769 / 0 / 9
tRNA-splicing endonuclease subunit Sen2 (EC 3.1.27.9) (tRNA-intron endonuclease Sen2) (HsSen2)Q8NCE0 0.0e+0 4.7e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		COG16769 / 0 / 9
tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (Leukocyte receptor cluster member 5) (tRNA-intron endonuclease Sen34) (HsSen34)Q9BSV6 0.0e+0 1.2e-1The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma.
J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.		COG16769 / 0 / 9
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