EVpedia 2.0

This menu provides the list of EV mRNAs identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote

Filter datasets:
- "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
- "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).

Maximum false positive rate (FPR): Maximum true positive rate (TPR):
  - FPR is the probability that an absent mRNA accidently have higher intensity than that mRNA.
  - TPR is the percentile of mRNA among the present mRNAs.
    Please see user manual in the contact us/help menu for detail.

Number of molecules in one page:

Since there are multiple primers in the microarray, the same mRNA can have several FPR and TPR values.

mRNA name	UniProt accession	FPR	TPR	Publication	Orthologous group	Identification count All / Prokaryote / Eukaryote (FPR<0.05,TPR<0.5)
Transcription factor RFX3 (Regulatory factor X 3)	P48381	1.0e-4	4.9e-1	Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.	ENOG410XSHE	13 / 0 / 13
Transcription factor RFX3 (Regulatory factor X 3)	P48380	0.0e+0	0.0e+0	Mesenchymal stem cell-derived microvesicles protect against acute tubular injury. J Am Soc Nephrol. 2009 May;20(5):1053-67. doi: 10.1681/ASN.2008070798. Epub 2009 Apr 23.	ENOG410XSHE	13 / 0 / 13
DNA-binding protein RFX5 (Regulatory factor X 5)	P48382	0.0e+0	3.3e-1	Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells. BMC Genomics. 2009 Nov 25;10:556. doi: 10.1186/1471-2164-10-556.	ENOG410XSHE	13 / 0 / 13
Transcription factor RFX3 (Regulatory factor X 3)	P48380	0.0e+0	4.9e-1	Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells. BMC Genomics. 2009 Nov 25;10:556. doi: 10.1186/1471-2164-10-556.	ENOG410XSHE	13 / 0 / 13
Transcription factor RFX3 (Regulatory factor X 3)	P48381	4.7e-4	4.6e-1	Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA. PLoS One. 2010 Dec 17;5(12):e15353. doi: 10.1371/journal.pone.0015353.	ENOG410XSHE	13 / 0 / 13
DNA-binding protein RFX5 (Regulatory factor X 5)	P48382	0.0e+0	2.9e-1	Identifying mRNA, microRNA and protein profiles of melanoma exosomes. PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.	ENOG410XSHE	13 / 0 / 13
DNA-binding protein RFX5 (Regulatory factor X 5)	P48382	0.0e+0	4.4e-1	Identifying mRNA, microRNA and protein profiles of melanoma exosomes. PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.	ENOG410XSHE	13 / 0 / 13
MHC class II regulatory factor RFX1 (Enhancer factor C) (EF-C) (Regulatory factor X 1) (RFX) (Transcription factor RFX1)	P22670	0.0e+0	4.6e-1	Identifying mRNA, microRNA and protein profiles of melanoma exosomes. PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.	ENOG410XSHE	13 / 0 / 13
DNA-binding protein RFX5 (Regulatory factor X 5)	P48382	3.1e-12	4.4e-1	Identifying mRNA, microRNA and protein profiles of melanoma exosomes. PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.	ENOG410XSHE	13 / 0 / 13
MHC class II regulatory factor RFX1 (Enhancer factor C) (EF-C) (Regulatory factor X 1) (RFX) (Transcription factor RFX1)	P22670	1.1e-11	4.5e-1	Identifying mRNA, microRNA and protein profiles of melanoma exosomes. PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.	ENOG410XSHE	13 / 0 / 13
Transcription factor RFX3 (Regulatory factor X 3)	P48380	1.4e-15	4.0e-1	Identifying mRNA, microRNA and protein profiles of melanoma exosomes. PLoS One. 2012;7(10):e46874. doi: 10.1371/journal.pone.0046874. Epub 2012 Oct 9.	ENOG410XSHE	13 / 0 / 13
MHC class II regulatory factor RFX1 (Enhancer factor C) (EF-C) (Regulatory factor X 1) (RFX) (Transcription factor RFX1)	P22670	0.0e+0	4.5e-1	First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications. Biol Cell. 2013 Jul;105(7):289-303. doi: 10.1111/boc.201200086. Epub 2013 May 4.	ENOG410XSHE	13 / 0 / 13
MHC class II regulatory factor RFX1 (Enhancer factor C) (EF-C) (Regulatory factor X 1) (RFX) (Transcription factor RFX1)	P22670	1.5e-5	4.6e-1	Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells. J Extracell Vesicles. 2012 Apr 16;1. doi: 10.3402/jev.v1i0.18389. eCollection 2012.	ENOG410XSHE	13 / 0 / 13
MHC class II regulatory factor RFX1 (Regulatory factor X 1) (Transcription factor RFX1)	P48377	0.0e+0	3.0e-1	Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.	ENOG410XSHE	13 / 0 / 13
Transcription factor RFX3 (Regulatory factor X 3)	P48381	0.0e+0	4.2e-2	Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.	ENOG410XSHE	13 / 0 / 13
MHC class II regulatory factor RFX1 (Regulatory factor X 1) (Transcription factor RFX1)	P48377	0.0e+0	4.0e-1	Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.	ENOG410XSHE	13 / 0 / 13
Transcription factor RFX3 (Regulatory factor X 3)	P48381	0.0e+0	2.1e-2	Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.	ENOG410XSHE	13 / 0 / 13
MHC class II regulatory factor RFX1 (Regulatory factor X 1) (Transcription factor RFX1)	P48377	0.0e+0	1.5e-1	Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.	ENOG410XSHE	13 / 0 / 13
Transcription factor RFX3 (Regulatory factor X 3)	P48381	0.0e+0	7.1e-4	Growth factor stimulation of cardiomyocytes induces changes in the transcriptional contents of secreted exosomes. J Extracell Vesicles. 2013 May 17;2. doi: 10.3402/jev.v2i0.20167. eCollection 2013.	ENOG410XSHE	13 / 0 / 13
DNA-binding protein RFX5 (Regulatory factor X 5)	P48382	0.0e+0	2.7e-1	The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma. J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.	ENOG410XSHE	13 / 0 / 13
DNA-binding protein RFX5 (Regulatory factor X 5)	P48382	0.0e+0	3.5e-1	The Three-Gene Signature in Urinary Extracellular Vesicles from Patients with Clear Cell Renal Cell Carcinoma. J Cancer. 2016 Sep 27;7(14):1960-1967. eCollection 2016.	ENOG410XSHE	13 / 0 / 13

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