This menu provides the list of EV proteins identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
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  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
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Protein name UniProt accession Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Quantitation of putative colorectal cancer biomarker candidates in serum extracellular vesicles by targeted proteomics.
Sci Rep. 2017 Oct 6;7(1):12782. doi: 10.1038/s41598-017-13092-x.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Quantitation of putative colorectal cancer biomarker candidates in serum extracellular vesicles by targeted proteomics.
Sci Rep. 2017 Oct 6;7(1):12782. doi: 10.1038/s41598-017-13092-x.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751The Human Amnion Epithelial Cell Secretome Decreases Hepatic Fibrosis in Mice with Chronic Liver Fibrosis.
Front Pharmacol. 2017 Oct 24;8:748. doi: 10.3389/fphar.2017.00748. eCollection 2017.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.
Sci Rep. 2017 Nov 10;7(1):15297. doi: 10.1038/s41598-017-15717-7.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.
Sci Rep. 2017 Nov 10;7(1):15297. doi: 10.1038/s41598-017-15717-7.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Nontypeable Haemophilus influenzae lysates increase heterogeneous nuclear ribonucleoprotein secretion and exosome release in human middle-ear epithelial cells.
FASEB J. 2017 Nov 30. pii: fj.201700248RR. doi: 10.1096/fj.201700248RR.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Nontypeable Haemophilus influenzae lysates increase heterogeneous nuclear ribonucleoprotein secretion and exosome release in human middle-ear epithelial cells.
FASEB J. 2017 Nov 30. pii: fj.201700248RR. doi: 10.1096/fj.201700248RR.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Nontypeable Haemophilus influenzae lysates increase heterogeneous nuclear ribonucleoprotein secretion and exosome release in human middle-ear epithelial cells.
FASEB J. 2017 Nov 30. pii: fj.201700248RR. doi: 10.1096/fj.201700248RR.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Nontypeable Haemophilus influenzae lysates increase heterogeneous nuclear ribonucleoprotein secretion and exosome release in human middle-ear epithelial cells.
FASEB J. 2017 Nov 30. pii: fj.201700248RR. doi: 10.1096/fj.201700248RR.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Tetraspanin CD63 bridges autophagic and endosomal processes to regulate exosomal secretion and intracellular signaling of Epstein-Barr virus LMP1.
J Virol. 2017 Dec 6. pii: JVI.01969-17. doi: 10.1128/JVI.01969-17.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Tetraspanin CD63 bridges autophagic and endosomal processes to regulate exosomal secretion and intracellular signaling of Epstein-Barr virus LMP1.
J Virol. 2017 Dec 6. pii: JVI.01969-17. doi: 10.1128/JVI.01969-17.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Amniotic fluid stem cell exosomes: Therapeutic perspective.
Biofactors. 2018 Jan 16. doi: 10.1002/biof.1407.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Extracellular vesicles from early-stage P. falciparum-infected red blood cells contain PfEMP1 and induce transcriptional changes in human monocytes.
Cell Microbiol. 2018 Jan 18. doi: 10.1111/cmi.12822.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Extracellular vesicles from early-stage P. falciparum-infected red blood cells contain PfEMP1 and induce transcriptional changes in human monocytes.
Cell Microbiol. 2018 Jan 18. doi: 10.1111/cmi.12822.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Hepatic stellate cell-derived PDGFRalpha-enriched extracellular vesicles promote liver fibrosis in mice through SHP2.
Hepatology. 2018 Jan 23. doi: 10.1002/hep.29803.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Hepatic stellate cell-derived PDGFRalpha-enriched extracellular vesicles promote liver fibrosis in mice through SHP2.
Hepatology. 2018 Jan 23. doi: 10.1002/hep.29803.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Hepatic stellate cell-derived PDGFRalpha-enriched extracellular vesicles promote liver fibrosis in mice through SHP2.
Hepatology. 2018 Jan 23. doi: 10.1002/hep.29803.
ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]P02751Biologically active constituents of the secretome of human W8B2(+) cardiac stem cells.
Sci Rep. 2018 Jan 25;8(1):1579. doi: 10.1038/s41598-018-19855-4.
ENOG410Y2NH401 / 0 / 401
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