This menu provides the list of EV proteins identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
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  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
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Protein name UniProt accession Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
Tubulin beta chain (Tubulin beta-5 chain)P07437Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.
Sci Rep. 2017 Aug 15;7(1):8202. doi: 10.1038/s41598-017-08392-1.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.
Sci Rep. 2017 Aug 15;7(1):8202. doi: 10.1038/s41598-017-08392-1.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Insulin mediated activation of PI3K/Akt signalling pathway modifies the proteomic cargo of extracellular vesicles.
Proteomics. 2017 Aug 26. doi: 10.1002/pmic.201600371.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Insulin mediated activation of PI3K/Akt signalling pathway modifies the proteomic cargo of extracellular vesicles.
Proteomics. 2017 Aug 26. doi: 10.1002/pmic.201600371.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Comprehensive proteomics analysis of exosomes derived from human seminal plasma.
Andrology. 2017 Sep;5(5):1007-1015. doi: 10.1111/andr.12412.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Radiation alters the cargo of exosomes released from squamous head and neck cancer cells to promote migration of recipient cells.
Sci Rep. 2017 Sep 29;7(1):12423. doi: 10.1038/s41598-017-12403-6.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Radiation alters the cargo of exosomes released from squamous head and neck cancer cells to promote migration of recipient cells.
Sci Rep. 2017 Sep 29;7(1):12423. doi: 10.1038/s41598-017-12403-6.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Quantitation of putative colorectal cancer biomarker candidates in serum extracellular vesicles by targeted proteomics.
Sci Rep. 2017 Oct 6;7(1):12782. doi: 10.1038/s41598-017-13092-x.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Quantitation of putative colorectal cancer biomarker candidates in serum extracellular vesicles by targeted proteomics.
Sci Rep. 2017 Oct 6;7(1):12782. doi: 10.1038/s41598-017-13092-x.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.
Sci Rep. 2017 Nov 10;7(1):15297. doi: 10.1038/s41598-017-15717-7.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies.
Sci Rep. 2017 Nov 10;7(1):15297. doi: 10.1038/s41598-017-15717-7.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Tetraspanin CD63 bridges autophagic and endosomal processes to regulate exosomal secretion and intracellular signaling of Epstein-Barr virus LMP1.
J Virol. 2017 Dec 6. pii: JVI.01969-17. doi: 10.1128/JVI.01969-17.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Tetraspanin CD63 bridges autophagic and endosomal processes to regulate exosomal secretion and intracellular signaling of Epstein-Barr virus LMP1.
J Virol. 2017 Dec 6. pii: JVI.01969-17. doi: 10.1128/JVI.01969-17.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Extracellular vesicles from early-stage P. falciparum-infected red blood cells contain PfEMP1 and induce transcriptional changes in human monocytes.
Cell Microbiol. 2018 Jan 18. doi: 10.1111/cmi.12822.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Extracellular vesicles from early-stage P. falciparum-infected red blood cells contain PfEMP1 and induce transcriptional changes in human monocytes.
Cell Microbiol. 2018 Jan 18. doi: 10.1111/cmi.12822.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Hepatic stellate cell-derived PDGFRalpha-enriched extracellular vesicles promote liver fibrosis in mice through SHP2.
Hepatology. 2018 Jan 23. doi: 10.1002/hep.29803.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Hepatic stellate cell-derived PDGFRalpha-enriched extracellular vesicles promote liver fibrosis in mice through SHP2.
Hepatology. 2018 Jan 23. doi: 10.1002/hep.29803.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Hepatic stellate cell-derived PDGFRalpha-enriched extracellular vesicles promote liver fibrosis in mice through SHP2.
Hepatology. 2018 Jan 23. doi: 10.1002/hep.29803.
COG5023544 / 0 / 544
Tubulin beta chain (Tubulin beta-5 chain)P07437Biologically active constituents of the secretome of human W8B2(+) cardiac stem cells.
Sci Rep. 2018 Jan 25;8(1):1579. doi: 10.1038/s41598-018-19855-4.
COG5023544 / 0 / 544
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