This menu provides the list of EV proteins identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
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  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
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Protein name UniProt accession Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase)B0U0L6Proteomic characterization and functional analysis of outer membrane vesicles of Francisella novicida suggests possible role in virulence and use as a vaccine.
J Proteome Res. 2011 Mar 4;10(3):954-67. doi: 10.1021/pr1009756. Epub 2011 Feb 9.
COG0105374 / 16 / 358
Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase)A6TCD7Klebsiella pneumoniae secretes outer membrane vesicles that induce the innate immune response.
FEMS Microbiol Lett. 2012 Jun;331(1):17-24. doi: 10.1111/j.1574-6968.2012.02549.x. Epub 2012 Apr 13.
COG0105374 / 16 / 358
Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase)Q59636Epoxide-Mediated Differential Packaging of Cif and other Virulence Factors into Outer Membrane Vesicles.
J Bacteriol. 2014 Aug 11. pii: JB.01760-14.
COG0105374 / 16 / 358
Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase)Q88PK1Proteomic characterization of the outer membrane vesicle of Pseudomonas putida KT2440.
J Proteome Res. 2014 Oct 3;13(10):4298-309. doi: 10.1021/pr500411d. Epub 2014 Sep 19.
COG0105374 / 16 / 358
Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase)Q8ZCT2Production of outer membrane vesicles by the plague pathogen Yersinia pestis.
PLoS One. 2014 Sep 8;9(9):e107002. doi: 10.1371/journal.pone.0107002. eCollection 2014.
COG0105374 / 16 / 358
Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase)Q59636Quantitative proteomics unravels that the post-transcriptional regulator Crc modulates the generation of vesicles and secreted virulence determinants of Pseudomonas aeruginosa.
J Proteomics. 2015 Sep 8;127(Pt B):352-64. doi: 10.1016/j.jprot.2015.06.009. Epub 2015 Jun 21.
COG0105374 / 16 / 358
Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase)Q59636Quantitative proteomics unravels that the post-transcriptional regulator Crc modulates the generation of vesicles and secreted virulence determinants of Pseudomonas aeruginosa.
J Proteomics. 2015 Sep 8;127(Pt B):352-64. doi: 10.1016/j.jprot.2015.06.009. Epub 2015 Jun 21.
COG0105374 / 16 / 358
Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase)Q59636Tracking the Dynamic Relationship between Cellular Systems and Extracellular Subproteomes in Pseudomonas aeruginosa Biofilms.
J Proteome Res. 2015 Nov 6;14(11):4524-37. doi: 10.1021/acs.jproteome.5b00262. Epub 2015 Oct 2.
COG0105374 / 16 / 358
Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase)Q59636Tracking the Dynamic Relationship between Cellular Systems and Extracellular Subproteomes in Pseudomonas aeruginosa Biofilms.
J Proteome Res. 2015 Nov 6;14(11):4524-37. doi: 10.1021/acs.jproteome.5b00262. Epub 2015 Oct 2.
COG0105374 / 16 / 358
Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase)Q59636Tracking the Dynamic Relationship between Cellular Systems and Extracellular Subproteomes in Pseudomonas aeruginosa Biofilms.
J Proteome Res. 2015 Nov 6;14(11):4524-37. doi: 10.1021/acs.jproteome.5b00262. Epub 2015 Oct 2.
COG0105374 / 16 / 358
Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase)P0A763Protective role of E. coli outer membrane vesicles against antibiotics.
Microbiol Res. 2015 Dec;181:1-7. doi: 10.1016/j.micres.2015.07.008. Epub 2015 Aug 1.
COG0105374 / 16 / 358
Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase)A6D2Z1Outer membrane vesicles containing signaling molecules and active hydrolytic enzymes released by a coral pathogen Vibrio shilonii AK1.
Environ Microbiol. 2016 Apr 21. doi: 10.1111/1462-2920.13344.
COG0105374 / 16 / 358
Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase)A6D2Z1Outer membrane vesicles containing signaling molecules and active hydrolytic enzymes released by a coral pathogen Vibrio shilonii AK1.
Environ Microbiol. 2016 Apr 21. doi: 10.1111/1462-2920.13344.
COG0105374 / 16 / 358
Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase)Q2FYG7Bacterial outer membrane vesicles suppress tumor by interferon-gamma-mediated antitumor response.
Nat Commun. 2017 Sep 20;8(1):626. doi: 10.1038/s41467-017-00729-8.
COG0105374 / 16 / 358
Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase)Q7VWK7Outer Membrane Vesicles (OMV)-based and proteomics-driven antigen selection identifies novel factors contributing to Bordetella pertussis adhesion to epithelial cells.
Mol Cell Proteomics. 2017 Dec 4. pii: RA117.000045. doi: 10.1074/mcp.RA117.000045.
COG0105374 / 16 / 358
Nucleoside diphosphate kinase (NDK) (NDP kinase) (EC 2.7.4.6) (Nucleoside-2-P kinase)Q7VWK7Outer Membrane Vesicles (OMV)-based and proteomics-driven antigen selection identifies novel factors contributing to Bordetella pertussis adhesion to epithelial cells.
Mol Cell Proteomics. 2017 Dec 4. pii: RA117.000045. doi: 10.1074/mcp.RA117.000045.
COG0105374 / 16 / 358
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