This menu provides the list of EV proteins identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
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  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
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Protein name UniProt accession Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
Peptidase, M1 (Aminopeptidase N) family (EC 3.4.11.-)Q1DEL1Profiling the outer membrane proteome during growth and development of the social bacterium Myxococcus xanthus by selective biotinylation and analyses of outer membrane vesicles.
J Proteome Res. 2010 Oct 1;9(10):5197-208. doi: 10.1021/pr1004983.
COG0308422 / 17 / 405
Aminopeptidase NB0TWE8Proteomic characterization and functional analysis of outer membrane vesicles of Francisella novicida suggests possible role in virulence and use as a vaccine.
J Proteome Res. 2011 Mar 4;10(3):954-67. doi: 10.1021/pr1009756. Epub 2011 Feb 9.
COG0308422 / 17 / 405
Aminopeptidase NQ9HZC5Identification of proteins associated with the Pseudomonas aeruginosa biofilm extracellular matrix.
J Proteome Res. 2012 Oct 5;11(10):4906-15. doi: 10.1021/pr300395j. Epub 2012 Sep 26.
COG0308422 / 17 / 405
Aminopeptidase (EC 3.4.11.-)Q8DQF1Characterization of protective extracellular membrane-derived vesicles produced by Streptococcus pneumoniae.
J Proteomics. 2014 Jun 25;106:46-60. doi: 10.1016/j.jprot.2014.04.023. Epub 2014 Apr 24.
COG0308422 / 17 / 405
Aminopeptidase (EC 3.4.11.-)Q8DQF1Characterization of protective extracellular membrane-derived vesicles produced by Streptococcus pneumoniae.
J Proteomics. 2014 Jun 25;106:46-60. doi: 10.1016/j.jprot.2014.04.023. Epub 2014 Apr 24.
COG0308422 / 17 / 405
Putative aminopeptidase N (EC 3.4.11.2)Q7CHK4Production of outer membrane vesicles by the plague pathogen Yersinia pestis.
PLoS One. 2014 Sep 8;9(9):e107002. doi: 10.1371/journal.pone.0107002. eCollection 2014.
COG0308422 / 17 / 405
Aminopeptidase (EC 3.4.11.-)Q1CXD4Composition of distinct sub-proteomes in Myxococcus xanthus: metabolic cost and amino acid availability.
Amino Acids. 2015 Jul 11.
COG0308422 / 17 / 405
Probable aminopeptidase N PepN (Lysyl aminopeptidase) (LYS-AP) (Alanine aminopeptidase)L7N655Proteomic analysis of extracellular vesicles derived from Mycobacterium tuberculosis.
Proteomics. 2015 Jul 23. doi: 10.1002/pmic.201500037.
COG0308422 / 17 / 405
Aminopeptidase NQ9HZC5Tracking the Dynamic Relationship between Cellular Systems and Extracellular Subproteomes in Pseudomonas aeruginosa Biofilms.
J Proteome Res. 2015 Nov 6;14(11):4524-37. doi: 10.1021/acs.jproteome.5b00262. Epub 2015 Oct 2.
COG0308422 / 17 / 405
Aminopeptidase NQ9HZC5Tracking the Dynamic Relationship between Cellular Systems and Extracellular Subproteomes in Pseudomonas aeruginosa Biofilms.
J Proteome Res. 2015 Nov 6;14(11):4524-37. doi: 10.1021/acs.jproteome.5b00262. Epub 2015 Oct 2.
COG0308422 / 17 / 405
Aminopeptidase NQ9HZC5Tracking the Dynamic Relationship between Cellular Systems and Extracellular Subproteomes in Pseudomonas aeruginosa Biofilms.
J Proteome Res. 2015 Nov 6;14(11):4524-37. doi: 10.1021/acs.jproteome.5b00262. Epub 2015 Oct 2.
COG0308422 / 17 / 405
Aminopeptidase NA6D6G2Outer membrane vesicles containing signaling molecules and active hydrolytic enzymes released by a coral pathogen Vibrio shilonii AK1.
Environ Microbiol. 2016 Apr 21. doi: 10.1111/1462-2920.13344.
COG0308422 / 17 / 405
Aminopeptidase NA6D6G2Outer membrane vesicles containing signaling molecules and active hydrolytic enzymes released by a coral pathogen Vibrio shilonii AK1.
Environ Microbiol. 2016 Apr 21. doi: 10.1111/1462-2920.13344.
COG0308422 / 17 / 405
Putative PEPTIDASEB2FUU5Proteomic analysis of outer membrane proteins and vesicles of a clinical isolate and a collection strain of Stenotrophomonas maltophilia.
J Proteomics. 2016 May 9. pii: S1874-3919(16)30187-7. doi: 10.1016/j.jprot.2016.05.001.
COG0308422 / 17 / 405
Aminopeptidase (EC 3.4.11.-)Q99ZG7A Two-Component Regulatory System Impacts Extracellular Membrane-Derived Vesicle Production in Group A Streptococcus.
MBio. 2016 Nov 1;7(6). pii: e00207-16. doi: 10.1128/mBio.00207-16.
COG0308422 / 17 / 405
Putative PEPTIDASEB2FUU5Membrane vesicle secretion and prophage induction in multidrug-resistant Stenotrophomonas maltophilia in response to ciprofloxacin stress.
Environ Microbiol. 2017 May 10. doi: 10.1111/1462-2920.13793.
COG0308422 / 17 / 405
Putative PEPTIDASEB2FUU5Membrane vesicle secretion and prophage induction in multidrug-resistant Stenotrophomonas maltophilia in response to ciprofloxacin stress.
Environ Microbiol. 2017 May 10. doi: 10.1111/1462-2920.13793.
COG0308422 / 17 / 405
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