This menu provides the list of EV proteins identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
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  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
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Protein name UniProt accession Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
Putative transferase CAF17, mitochondrial (EC 2.1.-.-) (Iron-sulfur cluster assembly factor homolog)Q5T440Human urinary exosomes as innate immune effectors.
J Am Soc Nephrol. 2014 Sep;25(9):2017-27. doi: 10.1681/ASN.2013101066. Epub 2014 Apr 3.
COG035414 / 9 / 5
Uncharacterized proteinQ9I5H0Epoxide-Mediated Differential Packaging of Cif and other Virulence Factors into Outer Membrane Vesicles.
J Bacteriol. 2014 Aug 11. pii: JB.01760-14.
COG035414 / 9 / 5
tRNA-modifying protein YgfZQ7CGT3Production of outer membrane vesicles by the plague pathogen Yersinia pestis.
PLoS One. 2014 Sep 8;9(9):e107002. doi: 10.1371/journal.pone.0107002. eCollection 2014.
COG035414 / 9 / 5
tRNA-modifying protein YgfZP0ADE8Protective role of E. coli outer membrane vesicles against antibiotics.
Microbiol Res. 2015 Dec;181:1-7. doi: 10.1016/j.micres.2015.07.008. Epub 2015 Aug 1.
COG035414 / 9 / 5
Putative transferase CAF17, mitochondrial (EC 2.1.-.-) (Iron-sulfur cluster assembly factor homolog)Q5T440Proteomic Analysis of Exosomes and Exosome-Free Conditioned Media Derived from Human Osteosarcoma Cell Lines Reveal Differential Secretion of Proteins Related to Biological Functions and Tumor Progression.
J Cell Biochem. 2016 Jun 30. doi: 10.1002/jcb.25642.
COG035414 / 9 / 5
tRNA-modifying protein YgfZA0A061L471Antibiotics and Iron-limiting conditions and their effect on the production and composition of outer membrane vesicles secreted from clinical isolates of extraintestinal pathogenic E. coli.
Proteomics Clin Appl. 2016 Sep 26. doi: 10.1002/prca.201600091.
COG035414 / 9 / 5
tRNA-modifying protein YgfZA0A061L471Antibiotics and Iron-limiting conditions and their effect on the production and composition of outer membrane vesicles secreted from clinical isolates of extraintestinal pathogenic E. coli.
Proteomics Clin Appl. 2016 Sep 26. doi: 10.1002/prca.201600091.
COG035414 / 9 / 5
tRNA-modifying protein YgfZA0A061L471Antibiotics and Iron-limiting conditions and their effect on the production and composition of outer membrane vesicles secreted from clinical isolates of extraintestinal pathogenic E. coli.
Proteomics Clin Appl. 2016 Sep 26. doi: 10.1002/prca.201600091.
COG035414 / 9 / 5
tRNA-modifying protein YgfZA0A061L471Antibiotics and Iron-limiting conditions and their effect on the production and composition of outer membrane vesicles secreted from clinical isolates of extraintestinal pathogenic E. coli.
Proteomics Clin Appl. 2016 Sep 26. doi: 10.1002/prca.201600091.
COG035414 / 9 / 5
tRNA-modifying protein YgfZA0A061L471Antibiotics and Iron-limiting conditions and their effect on the production and composition of outer membrane vesicles secreted from clinical isolates of extraintestinal pathogenic E. coli.
Proteomics Clin Appl. 2016 Sep 26. doi: 10.1002/prca.201600091.
COG035414 / 9 / 5
tRNA-modifying protein YgfZA0A061L471Antibiotics and Iron-limiting conditions and their effect on the production and composition of outer membrane vesicles secreted from clinical isolates of extraintestinal pathogenic E. coli.
Proteomics Clin Appl. 2016 Sep 26. doi: 10.1002/prca.201600091.
COG035414 / 9 / 5
Putative transferase CAF17, mitochondrial (EC 2.1.-.-) (Iron-sulfur cluster assembly factor homolog)Q5T440Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
COG035414 / 9 / 5
Putative transferase CAF17, mitochondrial (EC 2.1.-.-) (Iron-sulfur cluster assembly factor homolog)Q5T440Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
COG035414 / 9 / 5
IBA57 homolog, iron-sulfur cluster assemblyE1BC94Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth.
Sci Rep. 2017 Jul 19;7(1):5933. doi: 10.1038/s41598-017-06288-8.
COG035414 / 9 / 5
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