This menu provides the list of EV proteins identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
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  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
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Protein name UniProt accession Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q8BMJ2Characterization of vesicles secreted from insulinoma NIT-1 cells.
J Proteome Res. 2009 Jun;8(6):2851-62. doi: 10.1021/pr900009y.
COG0495211 / 12 / 199
LARS protein (Fragment)Q6NVI4Differential stimulation of monocytic cells results in distinct populations of microparticles.
J Thromb Haemost. 2009 Jun;7(6):1019-28. doi: 10.1111/j.1538-7836.2009.03434.x.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)P26637Characterization of yeast extracellular vesicles: evidence for the participation of different pathways of cellular traffic in vesicle biogenesis.
PLoS One. 2010 Jun 14;5(6):e11113. doi: 10.1371/journal.pone.0011113.
COG0495211 / 12 / 199
Leucyl-tRNA synthetaseQ5PPJ6Proteolipidic composition of exosomes changes during reticulocyte maturation.
J Biol Chem. 2011 Sep 30;286(39):34426-39. doi: 10.1074/jbc.M111.257444. Epub 2011 Aug 2.
COG0495211 / 12 / 199
Leucyl-tRNA synthetaseQ5PPJ6Proteolipidic composition of exosomes changes during reticulocyte maturation.
J Biol Chem. 2011 Sep 30;286(39):34426-39. doi: 10.1074/jbc.M111.257444. Epub 2011 Aug 2.
COG0495211 / 12 / 199
Leucyl-tRNA synthetaseQ5PPJ6Proteolipidic composition of exosomes changes during reticulocyte maturation.
J Biol Chem. 2011 Sep 30;286(39):34426-39. doi: 10.1074/jbc.M111.257444. Epub 2011 Aug 2.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT).
Proteomics. 2012 Jan;12(2):329-38. doi: 10.1002/pmic.201100477. Epub 2011 Dec 16.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5The protein interaction network of extracellular vesicles derived from human colorectal cancer cells.
J Proteome Res. 2012 Feb 3;11(2):1144-51. doi: 10.1021/pr200842h. Epub 2012 Jan 9.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes.
Methods. 2012 Feb;56(2):293-304. doi: 10.1016/j.ymeth.2012.01.002. Epub 2012 Jan 21.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes.
Methods. 2012 Feb;56(2):293-304. doi: 10.1016/j.ymeth.2012.01.002. Epub 2012 Jan 21.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts.
J Proteomics. 2012 Dec 21;77:344-56. doi: 10.1016/j.jprot.2012.09.008. Epub 2012 Sep 20.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Mol Cell Proteomics. 2013 Feb;12(2):343-55. doi: 10.1074/mcp.M112.022806. Epub 2012 Nov 15.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Mol Cell Proteomics. 2013 Feb;12(2):343-55. doi: 10.1074/mcp.M112.022806. Epub 2012 Nov 15.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Mol Cell Proteomics. 2013 Feb;12(2):343-55. doi: 10.1074/mcp.M112.022806. Epub 2012 Nov 15.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids.
Mol Cell Proteomics. 2013 Mar;12(3):587-98. doi: 10.1074/mcp.M112.021303. Epub 2012 Dec 10.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Characterization and proteomic analysis of ovarian cancer-derived exosomes.
J Proteomics. 2013 Jan 16;80C:171-182. doi: 10.1016/j.jprot.2012.12.029.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Characterization and proteomic analysis of ovarian cancer-derived exosomes.
J Proteomics. 2013 Jan 16;80C:171-182. doi: 10.1016/j.jprot.2012.12.029.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Proteome profiling of exosomes derived from human primary and metastatic colorectal cancer cells reveal differential expression of key metastatic factors and signal transduction components.
Proteomics. 2013 May;13(10-11):1672-86. doi: 10.1002/pmic.201200562.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Modulation of B-cell exosome proteins by gamma herpesvirus infection.
Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):E2925-33. doi: 10.1073/pnas.1303906110. Epub 2013 Jul 1.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Characterization of human thymic exosomes.
PLoS One. 2013 Jul 2;8(7):e67554. doi: 10.1371/journal.pone.0067554. Print 2013.
COG0495211 / 12 / 199
Probable leucine--tRNA ligase, mitochondrial (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q15031LRRK2 secretion in exosomes is regulated by 14-3-3.
Hum Mol Genet. 2013 Dec 15;22(24):4988-5000. doi: 10.1093/hmg/ddt346. Epub 2013 Jul 25.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes.
J Extracell Vesicles. 2012 Apr 16;1. doi: 10.3402/jev.v1i0.18396. eCollection 2012.
COG0495211 / 12 / 199
cDNA FLJ10595 fis, clone NT2RP2004791, moderately similar to PUTATIVE LEUCYL-TRNA SYNTHETASE, CYTOPLASMIC (EC 6.1.1.4)Q9NVP8Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.
J Extracell Vesicles. 2013 Dec 23;2. doi: 10.3402/jev.v2i0.22097. eCollection 2013.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.
J Extracell Vesicles. 2013 Dec 23;2. doi: 10.3402/jev.v2i0.22097. eCollection 2013.
COG0495211 / 12 / 199
cDNA FLJ10595 fis, clone NT2RP2004791, moderately similar to PUTATIVE LEUCYL-TRNA SYNTHETASE, CYTOPLASMIC (EC 6.1.1.4)Q9NVP8Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.
J Extracell Vesicles. 2013 Dec 23;2. doi: 10.3402/jev.v2i0.22097. eCollection 2013.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.
J Extracell Vesicles. 2013 Dec 23;2. doi: 10.3402/jev.v2i0.22097. eCollection 2013.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential expression of EMT factors.
Proteomics. 2014 Mar;14(6):699-712. doi: 10.1002/pmic.201300452. Epub 2014 Feb 16.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential expression of EMT factors.
Proteomics. 2014 Mar;14(6):699-712. doi: 10.1002/pmic.201300452. Epub 2014 Feb 16.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential expression of EMT factors.
Proteomics. 2014 Mar;14(6):699-712. doi: 10.1002/pmic.201300452. Epub 2014 Feb 16.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.
Biochem Biophys Res Commun. 2014 Mar 21;445(4):694-701. doi: 10.1016/j.bbrc.2013.12.070. Epub 2014 Jan 14.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5The overexpression of a single oncogene (ERBB2/HER2) alters the proteomic landscape of extracellular vesicles.
Proteomics. 2014 Jun;14(12):1472-9. doi: 10.1002/pmic.201300485. Epub 2014 May 15.
COG0495211 / 12 / 199
Putative leucyl-tRNA synthetase (EC 6.1.1.4)Q4QG44Absence of metalloprotease GP63 alters the protein content of Leishmania exosomes.
PLoS One. 2014 Apr 15;9(4):e95007. doi: 10.1371/journal.pone.0095007. eCollection 2014.
COG0495211 / 12 / 199
Putative leucyl-tRNA synthetase (EC 6.1.1.4)Q4QG44Absence of metalloprotease GP63 alters the protein content of Leishmania exosomes.
PLoS One. 2014 Apr 15;9(4):e95007. doi: 10.1371/journal.pone.0095007. eCollection 2014.
COG0495211 / 12 / 199
Putative leucyl-tRNA synthetase (EC 6.1.1.4)Q4QG44Absence of metalloprotease GP63 alters the protein content of Leishmania exosomes.
PLoS One. 2014 Apr 15;9(4):e95007. doi: 10.1371/journal.pone.0095007. eCollection 2014.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q8BMJ2Extracellular Vesicles from Neural Stem Cells Transfer IFN-gamma via Ifngr1 to Activate Stat1 Signaling in Target Cells.
Mol Cell. 2014 Sep 16. pii: S1097-2765(14)00675-3. doi: 10.1016/j.molcel.2014.08.020.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q8BMJ2Extracellular Vesicles from Neural Stem Cells Transfer IFN-gamma via Ifngr1 to Activate Stat1 Signaling in Target Cells.
Mol Cell. 2014 Sep 16. pii: S1097-2765(14)00675-3. doi: 10.1016/j.molcel.2014.08.020.
COG0495211 / 12 / 199
Probable leucine--tRNA ligase, mitochondrial (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q15031Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets.
Transfusion. 2014 Oct 21. doi: 10.1111/trf.12874.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q8BMJ2Membrane microvesicles as mediators for melanoma-fibroblasts communication: Roles of the VCAM-1/VLA-4 axis and the ERK1/2 signal pathway.
Cancer Lett. 2015 Feb 4. pii: S0304-3835(15)00066-X. doi: 10.1016/j.canlet.2015.01.032.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Methods. 2015 Apr 16. pii: S1046-2023(15)00154-1. doi: 10.1016/j.ymeth.2015.04.008.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Methods. 2015 Apr 16. pii: S1046-2023(15)00154-1. doi: 10.1016/j.ymeth.2015.04.008.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Methods. 2015 Apr 16. pii: S1046-2023(15)00154-1. doi: 10.1016/j.ymeth.2015.04.008.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes.
Oncotarget. 2015 Apr 12.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes.
Oncotarget. 2015 Apr 12.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines.
Pigment Cell Melanoma Res. 2015 May 7. doi: 10.1111/pcmr.12380.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines.
Pigment Cell Melanoma Res. 2015 May 7. doi: 10.1111/pcmr.12380.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines.
Pigment Cell Melanoma Res. 2015 May 7. doi: 10.1111/pcmr.12380.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q8BMJ2Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver.
Nat Cell Biol. 2015 May 18. doi: 10.1038/ncb3169.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts.
Blood. 2015 Jun 22. pii: blood-2014-12-618025.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts.
Blood. 2015 Jun 22. pii: blood-2014-12-618025.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q8BMJ2A comprehensive proteomics analysis reveals a secretory path- and status-dependent signature of exosomes released from tumor associated macrophages.
J Proteome Res. 2015 Aug 27.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q8BMJ2A comprehensive proteomics analysis reveals a secretory path- and status-dependent signature of exosomes released from tumor associated macrophages.
J Proteome Res. 2015 Aug 27.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Identification of developmental endothelial locus-1 on circulating extracellular vesicles as a novel biomarker for early breast cancer detection.
Clin Cancer Res. 2015 Nov 24. pii: clincanres.0654.2015.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Triple SILAC quantitative proteomic analysis reveals differential abundance of cell signaling proteins between normal and lung cancer-derived exosomes.
J Proteomics. 2015 Dec 28. pii: S1874-3919(15)30222-0. doi: 10.1016/j.jprot.2015.12.023.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Triple SILAC quantitative proteomic analysis reveals differential abundance of cell signaling proteins between normal and lung cancer-derived exosomes.
J Proteomics. 2015 Dec 28. pii: S1874-3919(15)30222-0. doi: 10.1016/j.jprot.2015.12.023.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Triple SILAC quantitative proteomic analysis reveals differential abundance of cell signaling proteins between normal and lung cancer-derived exosomes.
J Proteomics. 2015 Dec 28. pii: S1874-3919(15)30222-0. doi: 10.1016/j.jprot.2015.12.023.
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Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes.
Proc Natl Acad Sci U S A. 2016 Feb 8. pii: 201521230.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes.
Proc Natl Acad Sci U S A. 2016 Feb 8. pii: 201521230.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes.
Proc Natl Acad Sci U S A. 2016 Feb 8. pii: 201521230.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes.
Proc Natl Acad Sci U S A. 2016 Feb 8. pii: 201521230.
COG0495211 / 12 / 199
cDNA FLJ58157, highly similar to Leucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.4)B4DER1MSC secretes at least 3 EV types each with a unique permutation of membrane lipid, protein and RNA.
J Extracell Vesicles. 2016 Feb 24;5:29828. doi: 10.3402/jev.v5.29828. eCollection 2016.
COG0495211 / 12 / 199
cDNA FLJ58157, highly similar to Leucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.4)B4DER1MSC secretes at least 3 EV types each with a unique permutation of membrane lipid, protein and RNA.
J Extracell Vesicles. 2016 Feb 24;5:29828. doi: 10.3402/jev.v5.29828. eCollection 2016.
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Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q8BMJ2Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.
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Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q8BMJ2Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q8BMJ2Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.
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Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5ExtraPEG: a polyethylene glycol-based method for enrichment of extracellular vesicles.
Sci Rep. 2016 Apr 12;6:23978. doi: 10.1038/srep23978.
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Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Effective isolation of exosomes with polyethylene glycol from cell culture supernatant for in-depth proteome profiling.
Analyst. 2016 May 27.
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Probable leucine--tRNA ligase, mitochondrial (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q15031Effective isolation of exosomes with polyethylene glycol from cell culture supernatant for in-depth proteome profiling.
Analyst. 2016 May 27.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q8BMJ2Microvesicles provide a mechanism for intercellular communication by embryonic stem cells during embryo implantation.
Nat Commun. 2016 Jun 15;7:11958. doi: 10.1038/ncomms11958.
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Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Efficient production and enhanced tumor delivery of engineered extracellular vesicles.
Biomaterials. 2016 Jul 6;105:195-205. doi: 10.1016/j.biomaterials.2016.07.003.
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Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Efficient production and enhanced tumor delivery of engineered extracellular vesicles.
Biomaterials. 2016 Jul 6;105:195-205. doi: 10.1016/j.biomaterials.2016.07.003.
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Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q8BMJ2Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer.
Oncotarget. 2016 Aug 23. doi: 10.18632/oncotarget.11535.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q8BMJ2Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer.
Oncotarget. 2016 Aug 23. doi: 10.18632/oncotarget.11535.
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cDNA, FLJ96156, highly similar to Homo sapiens leucyl-tRNA synthetase (LARS), mRNAB2RCM2Secreted primary human malignant mesothelioma exosome signature reflects oncogenic cargo.
Sci Rep. 2016 Sep 8;6:32643. doi: 10.1038/srep32643.
COG0495211 / 12 / 199
cDNA, FLJ96156, highly similar to Homo sapiens leucyl-tRNA synthetase (LARS), mRNAB2RCM2Secreted primary human malignant mesothelioma exosome signature reflects oncogenic cargo.
Sci Rep. 2016 Sep 8;6:32643. doi: 10.1038/srep32643.
COG0495211 / 12 / 199
cDNA, FLJ96156, highly similar to Homo sapiens leucyl-tRNA synthetase (LARS), mRNAB2RCM2Secreted primary human malignant mesothelioma exosome signature reflects oncogenic cargo.
Sci Rep. 2016 Sep 8;6:32643. doi: 10.1038/srep32643.
COG0495211 / 12 / 199
cDNA, FLJ96156, highly similar to Homo sapiens leucyl-tRNA synthetase (LARS), mRNAB2RCM2Secreted primary human malignant mesothelioma exosome signature reflects oncogenic cargo.
Sci Rep. 2016 Sep 8;6:32643. doi: 10.1038/srep32643.
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Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Identification and Characterization of 293T Cell-Derived Exosomes by Profiling the Protein, mRNA and MicroRNA Components.
PLoS One. 2016 Sep 20;11(9):e0163043. doi: 10.1371/journal.pone.0163043. eCollection 2016.
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Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Proteomic and bioinformatic characterization of extracellular vesicles released from human macrophages upon influenza A virus infection.
J Proteome Res. 2016 Oct 11.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Proteomic and bioinformatic characterization of extracellular vesicles released from human macrophages upon influenza A virus infection.
J Proteome Res. 2016 Oct 11.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Candida albicans Modifies the Protein Composition and Size Distribution of THP1 macrophages-derived Extracellular Vesicles.
J Proteome Res. 2016 Oct 14.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Candida albicans Modifies the Protein Composition and Size Distribution of THP1 macrophages-derived Extracellular Vesicles.
J Proteome Res. 2016 Oct 14.
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Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Mycobacterium tuberculosis Infection Manipulates the Glycosylation Machinery and the N-Glycoproteome of Human Macrophages and their Microparticles.
J Proteome Res. 2016 Oct 19.
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Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Mycobacterium tuberculosis Infection Manipulates the Glycosylation Machinery and the N-Glycoproteome of Human Macrophages and their Microparticles.
J Proteome Res. 2016 Oct 19.
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Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Detailed Analysis of Protein Topology of Extracellular Vesicles-Evidence of Unconventional Membrane Protein Orientation.
Sci Rep. 2016 Nov 8;6:36338. doi: 10.1038/srep36338.
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Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q8BMJ2Thymic exosomes promote the final maturation of thymocytes.
Sci Rep. 2016 Nov 8;6:36479. doi: 10.1038/srep36479.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources.
J Extracell Vesicles. 2016 Nov 17;5:32570. doi: 10.3402/jev.v5.32570. eCollection 2016.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources.
J Extracell Vesicles. 2016 Nov 17;5:32570. doi: 10.3402/jev.v5.32570. eCollection 2016.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources.
J Extracell Vesicles. 2016 Nov 17;5:32570. doi: 10.3402/jev.v5.32570. eCollection 2016.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources.
J Extracell Vesicles. 2016 Nov 17;5:32570. doi: 10.3402/jev.v5.32570. eCollection 2016.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources.
J Extracell Vesicles. 2016 Nov 17;5:32570. doi: 10.3402/jev.v5.32570. eCollection 2016.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0495211 / 12 / 199
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)Q9P2J5Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0495211 / 12 / 199
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