This menu provides the list of EV proteins identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
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  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
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Protein name UniProt accession Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
PTS system mannose-specific EIIAB component (EC 2.7.1.191) (EIIAB-Man) (EIII-Man) [Includes: Mannose-specific phosphotransferase enzyme IIA component (PTS system mannose-specific EIIA component); Mannose-specific phosphotransferase enzyme IIB component (PTS system mannose-specific EIIB component)]P69800Comparative proteomic analysis of outer membrane vesicles from Shigella flexneri under different culture conditions.
Biochem Biophys Res Commun. 2014 Oct 31;453(4):696-702. doi: 10.1016/j.bbrc.2014.09.142. Epub 2014 Oct 14.
COG28939 / 9 / 0
PTS system mannose-specific EIIAB component (EC 2.7.1.191) (EIIAB-Man) (EIII-Man) [Includes: Mannose-specific phosphotransferase enzyme IIA component (PTS system mannose-specific EIIA component); Mannose-specific phosphotransferase enzyme IIB component (PTS system mannose-specific EIIB component)]P69797Protective role of E. coli outer membrane vesicles against antibiotics.
Microbiol Res. 2015 Dec;181:1-7. doi: 10.1016/j.micres.2015.07.008. Epub 2015 Aug 1.
COG28939 / 9 / 0
PTS system mannose-specific EIIAB component (EC 2.7.1.191) (EIIAB-Man) (EIII-Man) [Includes: Mannose-specific phosphotransferase enzyme IIA component (PTS system mannose-specific EIIA component); Mannose-specific phosphotransferase enzyme IIB component (PTS system mannose-specific EIIB component)]P69799Antibiotics and Iron-limiting conditions and their effect on the production and composition of outer membrane vesicles secreted from clinical isolates of extraintestinal pathogenic E. coli.
Proteomics Clin Appl. 2016 Sep 26. doi: 10.1002/prca.201600091.
COG28939 / 9 / 0
PTS system mannose-specific EIIAB component (EC 2.7.1.191) (EIIAB-Man) (EIII-Man) [Includes: Mannose-specific phosphotransferase enzyme IIA component (PTS system mannose-specific EIIA component); Mannose-specific phosphotransferase enzyme IIB component (PTS system mannose-specific EIIB component)]P69799Antibiotics and Iron-limiting conditions and their effect on the production and composition of outer membrane vesicles secreted from clinical isolates of extraintestinal pathogenic E. coli.
Proteomics Clin Appl. 2016 Sep 26. doi: 10.1002/prca.201600091.
COG28939 / 9 / 0
PTS system mannose-specific EIIAB component (EC 2.7.1.191) (EIIAB-Man) (EIII-Man) [Includes: Mannose-specific phosphotransferase enzyme IIA component (PTS system mannose-specific EIIA component); Mannose-specific phosphotransferase enzyme IIB component (PTS system mannose-specific EIIB component)]P69799Antibiotics and Iron-limiting conditions and their effect on the production and composition of outer membrane vesicles secreted from clinical isolates of extraintestinal pathogenic E. coli.
Proteomics Clin Appl. 2016 Sep 26. doi: 10.1002/prca.201600091.
COG28939 / 9 / 0
PTS system mannose-specific EIIAB component (EC 2.7.1.191) (EIIAB-Man) (EIII-Man) [Includes: Mannose-specific phosphotransferase enzyme IIA component (PTS system mannose-specific EIIA component); Mannose-specific phosphotransferase enzyme IIB component (PTS system mannose-specific EIIB component)]P69799Antibiotics and Iron-limiting conditions and their effect on the production and composition of outer membrane vesicles secreted from clinical isolates of extraintestinal pathogenic E. coli.
Proteomics Clin Appl. 2016 Sep 26. doi: 10.1002/prca.201600091.
COG28939 / 9 / 0
PTS system mannose-specific EIIAB component (EC 2.7.1.191) (EIIAB-Man) (EIII-Man) [Includes: Mannose-specific phosphotransferase enzyme IIA component (PTS system mannose-specific EIIA component); Mannose-specific phosphotransferase enzyme IIB component (PTS system mannose-specific EIIB component)]P69799Antibiotics and Iron-limiting conditions and their effect on the production and composition of outer membrane vesicles secreted from clinical isolates of extraintestinal pathogenic E. coli.
Proteomics Clin Appl. 2016 Sep 26. doi: 10.1002/prca.201600091.
COG28939 / 9 / 0
PTS system mannose-specific EIIAB component (EC 2.7.1.191) (EIIAB-Man) (EIII-Man) [Includes: Mannose-specific phosphotransferase enzyme IIA component (PTS system mannose-specific EIIA component); Mannose-specific phosphotransferase enzyme IIB component (PTS system mannose-specific EIIB component)]P69799Antibiotics and Iron-limiting conditions and their effect on the production and composition of outer membrane vesicles secreted from clinical isolates of extraintestinal pathogenic E. coli.
Proteomics Clin Appl. 2016 Sep 26. doi: 10.1002/prca.201600091.
COG28939 / 9 / 0
Mannose-specific phosphotransferase system component IIAB (EC 2.7.1.69)Q99YE6A Two-Component Regulatory System Impacts Extracellular Membrane-Derived Vesicle Production in Group A Streptococcus.
MBio. 2016 Nov 1;7(6). pii: e00207-16. doi: 10.1128/mBio.00207-16.
COG28939 / 9 / 0
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