This menu provides the list of EV proteins identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
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  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
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Protein name UniProt accession Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)O54890Analysis of the extracellular matrix vesicle proteome in mineralizing osteoblasts.
J Cell Physiol. 2007 Feb;210(2):325-35.		ENOG410XP60430 / 0 / 430
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)O54890Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections.
PLoS One. 2011;6(10):e26588. doi: 10.1371/journal.pone.0026588. Epub 2011 Oct 26.		ENOG410XP60430 / 0 / 430
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)O54890Exosomes from myeloid-derived suppressor cells carry biologically active proteins.
J Proteome Res. 2014 Feb 7;13(2):836-43. doi: 10.1021/pr400879c. Epub 2013 Dec 13.		ENOG410XP60430 / 0 / 430
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)O54890Membrane microvesicles as mediators for melanoma-fibroblasts communication: Roles of the VCAM-1/VLA-4 axis and the ERK1/2 signal pathway.
Cancer Lett. 2015 Feb 4. pii: S0304-3835(15)00066-X. doi: 10.1016/j.canlet.2015.01.032.		ENOG410XP60430 / 0 / 430
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)O54890Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver.
Nat Cell Biol. 2015 May 18. doi: 10.1038/ncb3169.		ENOG410XP60430 / 0 / 430
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)O54890Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.		ENOG410XP60430 / 0 / 430
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)O54890Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.		ENOG410XP60430 / 0 / 430
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)O54890Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.		ENOG410XP60430 / 0 / 430
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)O54890Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer.
Oncotarget. 2016 Aug 23. doi: 10.18632/oncotarget.11535.		ENOG410XP60430 / 0 / 430
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)O54890Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer.
Oncotarget. 2016 Aug 23. doi: 10.18632/oncotarget.11535.		ENOG410XP60430 / 0 / 430
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)O54890The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity.
Cell. 2016 Dec 1;167(6):1525-1539.e17. doi: 10.1016/j.cell.2016.11.005.		ENOG410XP60430 / 0 / 430
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)O54890The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity.
Cell. 2016 Dec 1;167(6):1525-1539.e17. doi: 10.1016/j.cell.2016.11.005.		ENOG410XP60430 / 0 / 430
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)O54890Exploring experimental cerebral malaria pathogenesis through the characterisation of host-derived plasma microparticle protein content.
Sci Rep. 2016 Dec 5;6:37871. doi: 10.1038/srep37871.		ENOG410XP60430 / 0 / 430
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)O54890Annexin-enriched osteoblast-derived vesicles act as an extracellular site of mineral nucleation within developing stem cell cultures.
Sci Rep. 2017 Oct 3;7(1):12639. doi: 10.1038/s41598-017-13027-6.		ENOG410XP60430 / 0 / 430
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)O54890Annexin-enriched osteoblast-derived vesicles act as an extracellular site of mineral nucleation within developing stem cell cultures.
Sci Rep. 2017 Oct 3;7(1):12639. doi: 10.1038/s41598-017-13027-6.		ENOG410XP60430 / 0 / 430
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)O54890Extracellular vesicles released by cardiomyocytes in a doxorubicin-induced cardiac injury mouse model contain protein biomarkers of early cardiac injury.
Clin Cancer Res. 2017 Oct 25. pii: clincanres.2046.2017. doi: 10.1158/1078-0432.CCR-17-2046.		ENOG410XP60430 / 0 / 430
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)O54890Extracellular vesicles released by cardiomyocytes in a doxorubicin-induced cardiac injury mouse model contain protein biomarkers of early cardiac injury.
Clin Cancer Res. 2017 Oct 25. pii: clincanres.2046.2017. doi: 10.1158/1078-0432.CCR-17-2046.		ENOG410XP60430 / 0 / 430
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)O54890Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.		ENOG410XP60430 / 0 / 430
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)O54890Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.		ENOG410XP60430 / 0 / 430
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)O54890Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.		ENOG410XP60430 / 0 / 430
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)O54890Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.		ENOG410XP60430 / 0 / 430
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)O54890Differential content of proteins, mRNAs, and miRNAs suggests that MDSC and their exosomes may mediate distinct immune suppressive functions.
J Proteome Res. 2017 Nov 15. doi: 10.1021/acs.jproteome.7b00646.		ENOG410XP60430 / 0 / 430
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)O54890Differential content of proteins, mRNAs, and miRNAs suggests that MDSC and their exosomes may mediate distinct immune suppressive functions.
J Proteome Res. 2017 Nov 15. doi: 10.1021/acs.jproteome.7b00646.		ENOG410XP60430 / 0 / 430
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