This menu provides the list of EV proteins identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
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  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
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Protein name UniProt accession Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Isolation and identification of potential urinary microparticle biomarkers of bladder cancer.
J Proteome Res. 2008 May;7(5):2088-96. doi: 10.1021/pr700775x. Epub 2008 Mar 29.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Differential stimulation of monocytic cells results in distinct populations of microparticles.
J Thromb Haemost. 2009 Jun;7(6):1019-28. doi: 10.1111/j.1538-7836.2009.03434.x.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Proteomics of microparticles after deep venous thrombosis.
Thromb Res. 2010 Jun;125(6):e269-74. doi: 10.1016/j.thromres.2010.01.019. Epub 2010 Feb 13.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT).
Proteomics. 2012 Jan;12(2):329-38. doi: 10.1002/pmic.201100477. Epub 2011 Dec 16.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Quantitative proteome profiling of normal human circulating microparticles.
J Proteome Res. 2012 Apr 6;11(4):2154-63. doi: 10.1021/pr200901p. Epub 2012 Mar 1.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability.
J Proteomics. 2012 Jun 27;75(12):3574-84. doi: 10.1016/j.jprot.2012.03.054. Epub 2012 Apr 10.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Cause or effect of arteriogenesis: compositional alterations of microparticles from CAD patients undergoing external counterpulsation therapy.
PLoS One. 2012;7(10):e46822. doi: 10.1371/journal.pone.0046822. Epub 2012 Oct 8.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Comparative and targeted proteomic analyses of urinary microparticles from bladder cancer and hernia patients.
J Proteome Res. 2012 Dec 7;11(12):5611-29. doi: 10.1021/pr3008732. Epub 2012 Oct 31.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Proteomic analysis of podocyte exosome-enriched fraction from normal human urine.
J Proteomics. 2013 Apr 26;82:193-229. doi: 10.1016/j.jprot.2013.01.012. Epub 2013 Jan 30.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Differential protein profiling of renal cell carcinoma urinary exosomes.
Mol Biosyst. 2013 Jun;9(6):1220-33. doi: 10.1039/c3mb25582d. Epub 2013 Mar 19.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
Proteomics. 2013 May;13(10-11):1667-71. doi: 10.1002/pmic.201200561. Epub 2013 Apr 23.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
Proteomics. 2013 May;13(10-11):1667-71. doi: 10.1002/pmic.201200561. Epub 2013 Apr 23.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions.
Proteomics. 2013 Jul;13(14):2125-34. doi: 10.1002/pmic.201200323.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties.
Mol Cell Proteomics. 2013 Aug;12(8):2205-19. doi: 10.1074/mcp.M113.028589. Epub 2013 May 8.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Malaria-infected erythrocyte-derived microvesicles mediate cellular communication within the parasite population and with the host immune system.
Cell Host Microbe. 2013 May 15;13(5):521-34. doi: 10.1016/j.chom.2013.04.009.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Characterization of human thymic exosomes.
PLoS One. 2013 Jul 2;8(7):e67554. doi: 10.1371/journal.pone.0067554. Print 2013.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Discovery of prognostic biomarker candidates of lacunar infarction by quantitative proteomics of microvesicles enriched plasma.
PLoS One. 2014 Apr 21;9(4):e94663. doi: 10.1371/journal.pone.0094663. eCollection 2014.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Discovery of prognostic biomarker candidates of lacunar infarction by quantitative proteomics of microvesicles enriched plasma.
PLoS One. 2014 Apr 21;9(4):e94663. doi: 10.1371/journal.pone.0094663. eCollection 2014.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Discovery of prognostic biomarker candidates of lacunar infarction by quantitative proteomics of microvesicles enriched plasma.
PLoS One. 2014 Apr 21;9(4):e94663. doi: 10.1371/journal.pone.0094663. eCollection 2014.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Discovery of prognostic biomarker candidates of lacunar infarction by quantitative proteomics of microvesicles enriched plasma.
PLoS One. 2014 Apr 21;9(4):e94663. doi: 10.1371/journal.pone.0094663. eCollection 2014.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes.
Sci Rep. 2014 Aug 29;4:6232. doi: 10.1038/srep06232.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets.
Transfusion. 2014 Oct 21. doi: 10.1111/trf.12874.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets.
Transfusion. 2014 Oct 21. doi: 10.1111/trf.12874.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433A New Workflow for Proteomic Analysis of Urinary Exosomes and Assessment in Cystinuria Patients.
J Proteome Res. 2014 Nov 12.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433A New Workflow for Proteomic Analysis of Urinary Exosomes and Assessment in Cystinuria Patients.
J Proteome Res. 2014 Nov 12.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Perturbations in the urinary exosome in transplant rejection.
Front Med (Lausanne). 2015 Jan 5;1:57. doi: 10.3389/fmed.2014.00057. eCollection 2014.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Identification of distinct circulating exosomes in Parkinson's disease.
Ann Clin Transl Neurol. 2015 Apr;2(4):353-61. doi: 10.1002/acn3.175. Epub 2015 Feb 6.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Exosome enrichment of human serum using multiple cycles of centrifugation.
Electrophoresis. 2015 May 23. doi: 10.1002/elps.201500131.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Exosome enrichment of human serum using multiple cycles of centrifugation.
Electrophoresis. 2015 May 23. doi: 10.1002/elps.201500131.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals.
J Extracell Vesicles. 2015 Jul 6;4:27378. doi: 10.3402/jev.v4.27378. eCollection 2015.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals.
J Extracell Vesicles. 2015 Jul 6;4:27378. doi: 10.3402/jev.v4.27378. eCollection 2015.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals.
J Extracell Vesicles. 2015 Jul 6;4:27378. doi: 10.3402/jev.v4.27378. eCollection 2015.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals.
J Extracell Vesicles. 2015 Jul 6;4:27378. doi: 10.3402/jev.v4.27378. eCollection 2015.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals.
J Extracell Vesicles. 2015 Jul 6;4:27378. doi: 10.3402/jev.v4.27378. eCollection 2015.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Exosomal clusterin, identified in the pericardial fluid, improves myocardial performance following MI through epicardial activation, enhanced arteriogenesis and reduced apoptosis.
Int J Cardiol. 2015 Jun 14;197:333-347. doi: 10.1016/j.ijcard.2015.06.008.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Exosomes as nanocarriers for systemic delivery of the Helicobacter pylori virulence factor CagA.
Sci Rep. 2016 Jan 7;6:18346. doi: 10.1038/srep18346.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Exosomes as nanocarriers for systemic delivery of the Helicobacter pylori virulence factor CagA.
Sci Rep. 2016 Jan 7;6:18346. doi: 10.1038/srep18346.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Proteomic characterization of circulating extracellular vesicles identifies novel serum myeloma associated markers.
J Proteomics. 2016 Jan 13. pii: S1874-3919(15)30214-1. doi: 10.1016/j.jprot.2015.12.016.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Enrichment of extracellular vesicles from tissues of the central nervous system by PROSPR.
Mol Neurodegener. 2016 May 23;11(1):41. doi: 10.1186/s13024-016-0108-1.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Proteomic Analysis of Exosomes and Exosome-Free Conditioned Media Derived from Human Osteosarcoma Cell Lines Reveal Differential Secretion of Proteins Related to Biological Functions and Tumor Progression.
J Cell Biochem. 2016 Jun 30. doi: 10.1002/jcb.25642.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Comparative proteomic analysis of extracellular vesicles isolated by acoustic trapping or differential centrifugation.
Anal Chem. 2016 Aug 3.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Comparative proteomic analysis of extracellular vesicles isolated by acoustic trapping or differential centrifugation.
Anal Chem. 2016 Aug 3.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Comparative proteomic analysis of extracellular vesicles isolated by acoustic trapping or differential centrifugation.
Anal Chem. 2016 Aug 3.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Comparative proteomic analysis of extracellular vesicles isolated by acoustic trapping or differential centrifugation.
Anal Chem. 2016 Aug 3.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Exosomal proteome analysis of cerebrospinal fluid detects biosignatures of neuromyelitis optica and multiple sclerosis.
Clin Chim Acta. 2016 Sep 5. pii: S0009-8981(16)30375-8. doi: 10.1016/j.cca.2016.09.001.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Exosomal proteome analysis of cerebrospinal fluid detects biosignatures of neuromyelitis optica and multiple sclerosis.
Clin Chim Acta. 2016 Sep 5. pii: S0009-8981(16)30375-8. doi: 10.1016/j.cca.2016.09.001.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Exosomal proteome analysis of cerebrospinal fluid detects biosignatures of neuromyelitis optica and multiple sclerosis.
Clin Chim Acta. 2016 Sep 5. pii: S0009-8981(16)30375-8. doi: 10.1016/j.cca.2016.09.001.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Exosome secretome and mediated signaling in breast cancer patients with nontuberculous mycobacterial disease.
Oncotarget. 2017 Feb 1. doi: 10.18632/oncotarget.14964.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Exosome secretome and mediated signaling in breast cancer patients with nontuberculous mycobacterial disease.
Oncotarget. 2017 Feb 1. doi: 10.18632/oncotarget.14964.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Exosome secretome and mediated signaling in breast cancer patients with nontuberculous mycobacterial disease.
Oncotarget. 2017 Feb 1. doi: 10.18632/oncotarget.14964.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Proteomic analysis of urinary extracellular vesicles from high Gleason score prostate cancer.
Sci Rep. 2017 Feb 17;7:42961. doi: 10.1038/srep42961.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Proteomic analysis of urinary extracellular vesicles from high Gleason score prostate cancer.
Sci Rep. 2017 Feb 17;7:42961. doi: 10.1038/srep42961.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Proteomic analysis of urinary extracellular vesicles from high Gleason score prostate cancer.
Sci Rep. 2017 Feb 17;7:42961. doi: 10.1038/srep42961.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Plasma Exosome Profiling of Cancer Patients by a Next Generation Systems Biology Approach.
Sci Rep. 2017 Feb 20;7:42741. doi: 10.1038/srep42741.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Plasma Exosome Profiling of Cancer Patients by a Next Generation Systems Biology Approach.
Sci Rep. 2017 Feb 20;7:42741. doi: 10.1038/srep42741.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Differential protein expression in exosomal samples taken from trauma patients.
Proteomics Clin Appl. 2017 May 25. doi: 10.1002/prca.201700061.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Multiple extracellular vesicle types in peritoneal dialysis effluent are prominent and contain known biomarkers.
PLoS One. 2017 Jun 8;12(6):e0178601. doi: 10.1371/journal.pone.0178601. eCollection 2017.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Multiple extracellular vesicle types in peritoneal dialysis effluent are prominent and contain known biomarkers.
PLoS One. 2017 Jun 8;12(6):e0178601. doi: 10.1371/journal.pone.0178601. eCollection 2017.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
P0443364 / 0 / 64
Immunoglobulin kappa variable 3-11 (Ig kappa chain V-III region VG)P04433Quantitation of putative colorectal cancer biomarker candidates in serum extracellular vesicles by targeted proteomics.
Sci Rep. 2017 Oct 6;7(1):12782. doi: 10.1038/s41598-017-13092-x.
P0443364 / 0 / 64
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