This menu provides the list of EV proteins identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
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  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
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Protein name UniProt accession Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Analysis of the extracellular matrix vesicle proteome in mineralizing osteoblasts.
J Cell Physiol. 2007 Feb;210(2):325-35.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Proteomic characterization of thymocyte-derived microvesicles and apoptotic bodies in BALB/c mice.
J Proteomics. 2011 Sep 6;74(10):2025-33. doi: 10.1016/j.jprot.2011.05.023. Epub 2011 May 19.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Extracellular Vesicles from Neural Stem Cells Transfer IFN-gamma via Ifngr1 to Activate Stat1 Signaling in Target Cells.
Mol Cell. 2014 Sep 16. pii: S1097-2765(14)00675-3. doi: 10.1016/j.molcel.2014.08.020.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Extracellular Vesicles from Neural Stem Cells Transfer IFN-gamma via Ifngr1 to Activate Stat1 Signaling in Target Cells.
Mol Cell. 2014 Sep 16. pii: S1097-2765(14)00675-3. doi: 10.1016/j.molcel.2014.08.020.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Membrane microvesicles as mediators for melanoma-fibroblasts communication: Roles of the VCAM-1/VLA-4 axis and the ERK1/2 signal pathway.
Cancer Lett. 2015 Feb 4. pii: S0304-3835(15)00066-X. doi: 10.1016/j.canlet.2015.01.032.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver.
Nat Cell Biol. 2015 May 18. doi: 10.1038/ncb3169.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Adipocyte exosomes promote melanoma aggressiveness through fatty acid oxidation: a novel mechanism linking obesity and cancer.
Cancer Res. 2016 May 23. pii: canres.0651.2016.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Enrichment of extracellular vesicles from tissues of the central nervous system by PROSPR.
Mol Neurodegener. 2016 May 23;11(1):41. doi: 10.1186/s13024-016-0108-1.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Microvesicles provide a mechanism for intercellular communication by embryonic stem cells during embryo implantation.
Nat Commun. 2016 Jun 15;7:11958. doi: 10.1038/ncomms11958.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer.
Oncotarget. 2016 Aug 23. doi: 10.18632/oncotarget.11535.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer.
Oncotarget. 2016 Aug 23. doi: 10.18632/oncotarget.11535.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer.
Oncotarget. 2016 Aug 23. doi: 10.18632/oncotarget.11535.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Macrophage Foam Cell-Derived Extracellular Vesicles Promote Vascular Smooth Muscle Cell Migration and Adhesion.
J Am Heart Assoc. 2016 Oct 17;5(10). pii: e004099.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Secreted Glioblastoma Nanovesicles Contain Intracellular Signaling Proteins and Active Ras Incorporated in a Farnesylation-dependent Manner.
J Biol Chem. 2016 Dec 1. pii: jbc.M116.747618.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Exploring experimental cerebral malaria pathogenesis through the characterisation of host-derived plasma microparticle protein content.
Sci Rep. 2016 Dec 5;6:37871. doi: 10.1038/srep37871.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Exploring experimental cerebral malaria pathogenesis through the characterisation of host-derived plasma microparticle protein content.
Sci Rep. 2016 Dec 5;6:37871. doi: 10.1038/srep37871.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Characterisation of adipocyte-derived extracellular vesicle subtypes identifies distinct protein and lipid signatures for large and small extracellular vesicles.
J Extracell Vesicles. 2017 Apr 10;6(1):1305677. doi: 10.1080/20013078.2017.1305677. eCollection 2017.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Hypoxia-induced changes in the fibroblast secretome, exosome, and whole-cell proteome using cultured, cardiac-derived cells isolated from neonatal mice.
J Proteome Res. 2017 Jun 22. doi: 10.1021/acs.jproteome.7b00144.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Increased Release of Apolipoprotein E in Extracellular Vesicles Following Amyloid-beta Protofibril Exposure of Neuroglial Co-Cultures.
J Alzheimers Dis. 2017 Aug 17. doi: 10.3233/JAD-170278.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Differential content of proteins, mRNAs, and miRNAs suggests that MDSC and their exosomes may mediate distinct immune suppressive functions.
J Proteome Res. 2017 Nov 15. doi: 10.1021/acs.jproteome.7b00646.		COG2032275 / 22 / 253
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1)P08228Differential content of proteins, mRNAs, and miRNAs suggests that MDSC and their exosomes may mediate distinct immune suppressive functions.
J Proteome Res. 2017 Nov 15. doi: 10.1021/acs.jproteome.7b00646.		COG2032275 / 22 / 253
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