This menu provides the list of EV proteins identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
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  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
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Protein name UniProt accession Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteomic analysis of human prostasomes.
Prostate. 2003 Jul 1;56(2):150-61.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Identification and proteomic profiling of exosomes in human urine.
Proc Natl Acad Sci U S A. 2004 Sep 7;101(36):13368-73. Epub 2004 Aug 23.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021The platelet microparticle proteome.
J Proteome Res. 2005 Sep-Oct;4(5):1516-21.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization.
Proteomics. 2006 Jan;6(1):153-71.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteomic analysis of microvesicles derived from human colorectal cancer cells.
J Proteome Res. 2007 Dec;6(12):4646-55. Epub 2007 Oct 24.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Isolation and identification of potential urinary microparticle biomarkers of bladder cancer.
J Proteome Res. 2008 May;7(5):2088-96. doi: 10.1021/pr700775x. Epub 2008 Mar 29.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Isolation and identification of potential urinary microparticle biomarkers of bladder cancer.
J Proteome Res. 2008 May;7(5):2088-96. doi: 10.1021/pr700775x. Epub 2008 Mar 29.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles.
Proteomics. 2008 Jun;8(12):2430-46. doi: 10.1002/pmic.200701029.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles.
Proteomics. 2008 Jun;8(12):2430-46. doi: 10.1002/pmic.200701029.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles.
Proteomics. 2008 Jun;8(12):2430-46. doi: 10.1002/pmic.200701029.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Large-scale proteomics and phosphoproteomics of urinary exosomes.
J Am Soc Nephrol. 2009 Feb;20(2):363-79. doi: 10.1681/ASN.2008040406. Epub 2008 Dec 3.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
J Proteome Res. 2009 Mar;8(3):1304-14. doi: 10.1021/pr800658c.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures.
Blood. 2009 Jul 16;114(3):723-32. doi: 10.1182/blood-2009-02-205930. Epub 2009 Apr 15.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Differential stimulation of monocytic cells results in distinct populations of microparticles.
J Thromb Haemost. 2009 Jun;7(6):1019-28. doi: 10.1111/j.1538-7836.2009.03434.x.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Differential stimulation of monocytic cells results in distinct populations of microparticles.
J Thromb Haemost. 2009 Jun;7(6):1019-28. doi: 10.1111/j.1538-7836.2009.03434.x.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Differential stimulation of monocytic cells results in distinct populations of microparticles.
J Thromb Haemost. 2009 Jun;7(6):1019-28. doi: 10.1111/j.1538-7836.2009.03434.x.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Differential stimulation of monocytic cells results in distinct populations of microparticles.
J Thromb Haemost. 2009 Jun;7(6):1019-28. doi: 10.1111/j.1538-7836.2009.03434.x.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteomics, metabolomics, and immunomics on microparticles derived from human atherosclerotic plaques.
Circ Cardiovasc Genet. 2009 Aug;2(4):379-88. doi: 10.1161/CIRCGENETICS.108.842849. Epub 2009 May 14.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Mol Cell Proteomics. 2010 Jun;9(6):1085-99. doi: 10.1074/mcp.M900381-MCP200. Epub 2010 Feb 1.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteomics analysis of bladder cancer exosomes.
Mol Cell Proteomics. 2010 Jun;9(6):1324-38. doi: 10.1074/mcp.M000063-MCP201. Epub 2010 Mar 11.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Immunol Cell Biol. 2010 Nov-Dec;88(8):851-6. doi: 10.1038/icb.2010.64. Epub 2010 May 11.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021The plasma microparticle proteome.
Semin Thromb Hemost. 2010 Nov;36(8):845-56. doi: 10.1055/s-0030-1267038. Epub 2010 Nov 3.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Morphologic and proteomic characterization of exosomes released by cultured extravillous trophoblast cells.
Exp Cell Res. 2011 May 1;317(8):1192-202. doi: 10.1016/j.yexcr.2011.01.014. Epub 2011 Jan 26.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Protein profile of exosomes from trabecular meshwork cells.
J Proteomics. 2011 May 16;74(6):796-804. doi: 10.1016/j.jprot.2011.02.024. Epub 2011 Mar 8.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteomic characterization of biogenesis and functions of matrix vesicles released from mineralizing human osteoblast-like cells.
J Proteomics. 2011 Jun 10;74(7):1123-34. doi: 10.1016/j.jprot.2011.04.005. Epub 2011 Apr 15.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Proteomics. 2011 Jun;11(12):2459-75. doi: 10.1002/pmic.201000443. Epub 2011 May 18.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Proteomics. 2011 Jun;11(12):2459-75. doi: 10.1002/pmic.201000443. Epub 2011 May 18.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Proteomics. 2011 Jun;11(12):2459-75. doi: 10.1002/pmic.201000443. Epub 2011 May 18.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Expression of PTRF in PC-3 Cells modulates cholesterol dynamics and the actin cytoskeleton impacting secretion pathways.
Mol Cell Proteomics. 2012 Feb;11(2):M111.012245. doi: 10.1074/mcp.M111.012245. Epub 2011 Oct 26.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT).
Proteomics. 2012 Jan;12(2):329-38. doi: 10.1002/pmic.201100477. Epub 2011 Dec 16.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteomic analysis of microvesicles derived from human mesenchymal stem cells.
J Proteome Res. 2012 Feb 3;11(2):839-49. doi: 10.1021/pr200682z. Epub 2011 Dec 28.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021The protein interaction network of extracellular vesicles derived from human colorectal cancer cells.
J Proteome Res. 2012 Feb 3;11(2):1144-51. doi: 10.1021/pr200842h. Epub 2012 Jan 9.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes.
Methods. 2012 Feb;56(2):293-304. doi: 10.1016/j.ymeth.2012.01.002. Epub 2012 Jan 21.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes.
Methods. 2012 Feb;56(2):293-304. doi: 10.1016/j.ymeth.2012.01.002. Epub 2012 Jan 21.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes.
Methods. 2012 Feb;56(2):293-304. doi: 10.1016/j.ymeth.2012.01.002. Epub 2012 Jan 21.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Quantitative proteome profiling of normal human circulating microparticles.
J Proteome Res. 2012 Apr 6;11(4):2154-63. doi: 10.1021/pr200901p. Epub 2012 Mar 1.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Kidney Int. 2012 Jun;81(12):1263-72. doi: 10.1038/ki.2012.25. Epub 2012 Mar 14.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.
Nat Med. 2012 Jun;18(6):883-91. doi: 10.1038/nm.2753.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021The proteome of erythrocyte-derived microparticles from plasma: new clues for erythrocyte aging and vesiculation.
J Proteomics. 2012 Dec 5;76 Spec No.:203-10. doi: 10.1016/j.jprot.2012.05.031. Epub 2012 Jun 2.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Medulloblastoma exosome proteomics yield functional roles for extracellular vesicles.
PLoS One. 2012;7(7):e42064. doi: 10.1371/journal.pone.0042064. Epub 2012 Jul 27.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteolytic Potential of the MSC Exosome Proteome: Implications for an Exosome-Mediated Delivery of Therapeutic Proteasome.
Int J Proteomics. 2012;2012:971907. doi: 10.1155/2012/971907. Epub 2012 Jul 18.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts.
J Proteomics. 2012 Dec 21;77:344-56. doi: 10.1016/j.jprot.2012.09.008. Epub 2012 Sep 20.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts.
J Proteomics. 2012 Dec 21;77:344-56. doi: 10.1016/j.jprot.2012.09.008. Epub 2012 Sep 20.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Cause or effect of arteriogenesis: compositional alterations of microparticles from CAD patients undergoing external counterpulsation therapy.
PLoS One. 2012;7(10):e46822. doi: 10.1371/journal.pone.0046822. Epub 2012 Oct 8.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Mol Cell Proteomics. 2013 Feb;12(2):343-55. doi: 10.1074/mcp.M112.022806. Epub 2012 Nov 15.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Mol Cell Proteomics. 2013 Feb;12(2):343-55. doi: 10.1074/mcp.M112.022806. Epub 2012 Nov 15.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Mol Cell Proteomics. 2013 Feb;12(2):343-55. doi: 10.1074/mcp.M112.022806. Epub 2012 Nov 15.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids.
Mol Cell Proteomics. 2013 Mar;12(3):587-98. doi: 10.1074/mcp.M112.021303. Epub 2012 Dec 10.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids.
Mol Cell Proteomics. 2013 Mar;12(3):587-98. doi: 10.1074/mcp.M112.021303. Epub 2012 Dec 10.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids.
Mol Cell Proteomics. 2013 Mar;12(3):587-98. doi: 10.1074/mcp.M112.021303. Epub 2012 Dec 10.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Characterization and proteomic analysis of ovarian cancer-derived exosomes.
J Proteomics. 2013 Jan 16;80C:171-182. doi: 10.1016/j.jprot.2012.12.029.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Characterization and proteomic analysis of ovarian cancer-derived exosomes.
J Proteomics. 2013 Jan 16;80C:171-182. doi: 10.1016/j.jprot.2012.12.029.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteomic analysis of podocyte exosome-enriched fraction from normal human urine.
J Proteomics. 2013 Apr 26;82:193-229. doi: 10.1016/j.jprot.2013.01.012. Epub 2013 Jan 30.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021A comprehensive characterization of membrane vesicles released by autophagic human endothelial cells.
Proteomics. 2013 Apr;13(7):1108-20. doi: 10.1002/pmic.201200531.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteome profiling of exosomes derived from human primary and metastatic colorectal cancer cells reveal differential expression of key metastatic factors and signal transduction components.
Proteomics. 2013 May;13(10-11):1672-86. doi: 10.1002/pmic.201200562.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteome profiling of exosomes derived from human primary and metastatic colorectal cancer cells reveal differential expression of key metastatic factors and signal transduction components.
Proteomics. 2013 May;13(10-11):1672-86. doi: 10.1002/pmic.201200562.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions.
Proteomics. 2013 Jul;13(14):2125-34. doi: 10.1002/pmic.201200323.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteomic characterization of human platelet-derived microparticles.
Anal Chim Acta. 2013 May 7;776:57-63. doi: 10.1016/j.aca.2013.03.023. Epub 2013 Mar 19.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties.
Mol Cell Proteomics. 2013 Aug;12(8):2205-19. doi: 10.1074/mcp.M113.028589. Epub 2013 May 8.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties.
Mol Cell Proteomics. 2013 Aug;12(8):2205-19. doi: 10.1074/mcp.M113.028589. Epub 2013 May 8.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Malaria-infected erythrocyte-derived microvesicles mediate cellular communication within the parasite population and with the host immune system.
Cell Host Microbe. 2013 May 15;13(5):521-34. doi: 10.1016/j.chom.2013.04.009.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Modulation of B-cell exosome proteins by gamma herpesvirus infection.
Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):E2925-33. doi: 10.1073/pnas.1303906110. Epub 2013 Jul 1.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Characterization of human thymic exosomes.
PLoS One. 2013 Jul 2;8(7):e67554. doi: 10.1371/journal.pone.0067554. Print 2013.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis.
PLoS One. 2013 Jul 8;8(7):e68451. doi: 10.1371/journal.pone.0068451. Print 2013.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Characterization of multiple myeloma vesicles by label-free relative quantitation.
Proteomics. 2013 Oct;13(20):3013-29. doi: 10.1002/pmic.201300142.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Characterization of multiple myeloma vesicles by label-free relative quantitation.
Proteomics. 2013 Oct;13(20):3013-29. doi: 10.1002/pmic.201300142.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells.
J Extracell Vesicles. 2012 Sep 11;1. doi: 10.3402/jev.v1i0.18704. eCollection 2012.
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78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells.
J Extracell Vesicles. 2012 Sep 11;1. doi: 10.3402/jev.v1i0.18704. eCollection 2012.
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78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes.
J Extracell Vesicles. 2012 Apr 16;1. doi: 10.3402/jev.v1i0.18396. eCollection 2012.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteome profiling of neuroblastoma-derived exosomes reveal the expression of proteins potentially involved in tumor progression.
PLoS One. 2013 Sep 19;8(9):e75054. doi: 10.1371/journal.pone.0075054. eCollection 2013.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.
J Extracell Vesicles. 2013 Dec 23;2. doi: 10.3402/jev.v2i0.22097. eCollection 2013.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.
J Extracell Vesicles. 2013 Dec 23;2. doi: 10.3402/jev.v2i0.22097. eCollection 2013.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential expression of EMT factors.
Proteomics. 2014 Mar;14(6):699-712. doi: 10.1002/pmic.201300452. Epub 2014 Feb 16.
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78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential expression of EMT factors.
Proteomics. 2014 Mar;14(6):699-712. doi: 10.1002/pmic.201300452. Epub 2014 Feb 16.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential expression of EMT factors.
Proteomics. 2014 Mar;14(6):699-712. doi: 10.1002/pmic.201300452. Epub 2014 Feb 16.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.
PLoS One. 2013 Dec 31;8(12):e82589. doi: 10.1371/journal.pone.0082589. eCollection 2013.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.
PLoS One. 2013 Dec 31;8(12):e82589. doi: 10.1371/journal.pone.0082589. eCollection 2013.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.
PLoS One. 2013 Dec 31;8(12):e82589. doi: 10.1371/journal.pone.0082589. eCollection 2013.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer.
PLoS One. 2013 Dec 31;8(12):e82589. doi: 10.1371/journal.pone.0082589. eCollection 2013.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration.
J Proteome Res. 2014 Feb 7;13(2):581-95. doi: 10.1021/pr400751k. Epub 2014 Jan 16.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.
Biochem Biophys Res Commun. 2014 Mar 21;445(4):694-701. doi: 10.1016/j.bbrc.2013.12.070. Epub 2014 Jan 14.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Molecular characterization of exosome-like vesicles from breast cancer cells.
BMC Cancer. 2014 Jan 27;14:44. doi: 10.1186/1471-2407-14-44.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Plasma biomarker discovery in preeclampsia using a novel differential isolation technology for circulating extracellular vesicles.
Am J Obstet Gynecol. 2014 Mar 18. pii: S0002-9378(14)00248-8. doi: 10.1016/j.ajog.2014.03.038.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Quantitative proteomics of extracellular vesicles released from human monocyte-derived macrophages upon beta-glucan stimulation.
J Proteome Res. 2014 May 2;13(5):2468-77. doi: 10.1021/pr4012552. Epub 2014 Apr 16.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteins recruited to exosomes by tau overexpression implicate novel cellular mechanisms linking tau secretion with Alzheimer's disease.
J Alzheimers Dis. 2014;40 Suppl 1:S47-70. doi: 10.3233/JAD-132135.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteomic analysis of hypoxia-induced U373MG glioma secretome reveals novel hypoxia-dependent migration factors.
Proteomics. 2014 Jun;14(12):1494-502. doi: 10.1002/pmic.201300554. Epub 2014 May 16.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteomic analysis of hypoxia-induced U373MG glioma secretome reveals novel hypoxia-dependent migration factors.
Proteomics. 2014 Jun;14(12):1494-502. doi: 10.1002/pmic.201300554. Epub 2014 May 16.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021The overexpression of a single oncogene (ERBB2/HER2) alters the proteomic landscape of extracellular vesicles.
Proteomics. 2014 Jun;14(12):1472-9. doi: 10.1002/pmic.201300485. Epub 2014 May 15.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021The overexpression of a single oncogene (ERBB2/HER2) alters the proteomic landscape of extracellular vesicles.
Proteomics. 2014 Jun;14(12):1472-9. doi: 10.1002/pmic.201300485. Epub 2014 May 15.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021The overexpression of a single oncogene (ERBB2/HER2) alters the proteomic landscape of extracellular vesicles.
Proteomics. 2014 Jun;14(12):1472-9. doi: 10.1002/pmic.201300485. Epub 2014 May 15.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021The overexpression of a single oncogene (ERBB2/HER2) alters the proteomic landscape of extracellular vesicles.
Proteomics. 2014 Jun;14(12):1472-9. doi: 10.1002/pmic.201300485. Epub 2014 May 15.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Proteomic analysis of cerebrospinal fluid extracellular vesicles: a comprehensive dataset.
J Proteomics. 2014 Jun 25;106:191-204. doi: 10.1016/j.jprot.2014.04.028. Epub 2014 Apr 24.
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78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Human T-lymphotropic Virus Type 1-infected Cells Secrete Exosomes That Contain Tax Protein.
J Biol Chem. 2014 Aug 8;289(32):22284-305. doi: 10.1074/jbc.M114.549659. Epub 2014 Jun 17.
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78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Pathologic Mechanical Stress and Endotoxin Exposure Increases Lung Endothelial Microparticle Shedding.
Am J Respir Cell Mol Biol. 2014 Jul 16.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Pathologic Mechanical Stress and Endotoxin Exposure Increases Lung Endothelial Microparticle Shedding.
Am J Respir Cell Mol Biol. 2014 Jul 16.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Pathologic Mechanical Stress and Endotoxin Exposure Increases Lung Endothelial Microparticle Shedding.
Am J Respir Cell Mol Biol. 2014 Jul 16.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Pathologic Mechanical Stress and Endotoxin Exposure Increases Lung Endothelial Microparticle Shedding.
Am J Respir Cell Mol Biol. 2014 Jul 16.
COG0443608 / 40 / 568
78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Antibody-coupled monolithic silica microtips for highthroughput molecular profiling of circulating exosomes.
Sci Rep. 2014 Aug 29;4:6232. doi: 10.1038/srep06232.
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78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh-7 Cells Using SILAC Labeling and LC-MS/MS.
J Proteome Res. 2014 Oct 8.
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78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)P11021Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh-7 Cells Using SILAC Labeling and LC-MS/MS.
J Proteome Res. 2014 Oct 8.
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