This menu provides the list of EV proteins identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
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  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
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Protein name UniProt accession Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
Fibronectin (FN) [Cleaved into: Anastellin]P11276Analysis of the extracellular matrix vesicle proteome in mineralizing osteoblasts.
J Cell Physiol. 2007 Feb;210(2):325-35.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Identification and characterization of microvesicles secreted by 3T3-L1 adipocytes: redox- and hormone-dependent induction of milk fat globule-epidermal growth factor 8-associated microvesicles.
Endocrinology. 2007 Aug;148(8):3850-62. Epub 2007 May 3.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections.
PLoS One. 2011;6(10):e26588. doi: 10.1371/journal.pone.0026588. Epub 2011 Oct 26.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration.
Cell. 2012 Dec 21;151(7):1542-56. doi: 10.1016/j.cell.2012.11.024.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Exosomes from myeloid-derived suppressor cells carry biologically active proteins.
J Proteome Res. 2014 Feb 7;13(2):836-43. doi: 10.1021/pr400879c. Epub 2013 Dec 13.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Exosomes from myeloid-derived suppressor cells carry biologically active proteins.
J Proteome Res. 2014 Feb 7;13(2):836-43. doi: 10.1021/pr400879c. Epub 2013 Dec 13.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells.
Biochem Biophys Res Commun. 2014 Mar 7;445(2):327-33. doi: 10.1016/j.bbrc.2014.01.183. Epub 2014 Feb 7.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells.
Biochem Biophys Res Commun. 2014 Mar 7;445(2):327-33. doi: 10.1016/j.bbrc.2014.01.183. Epub 2014 Feb 7.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Circulating Extracellular Vesicles with Specific Proteome and Liver MicroRNAs Are Potential Biomarkers for Liver Injury in Experimental Fatty Liver Disease.
PLoS One. 2014 Dec 3;9(12):e113651. doi: 10.1371/journal.pone.0113651. eCollection 2014.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Membrane microvesicles as mediators for melanoma-fibroblasts communication: Roles of the VCAM-1/VLA-4 axis and the ERK1/2 signal pathway.
Cancer Lett. 2015 Feb 4. pii: S0304-3835(15)00066-X. doi: 10.1016/j.canlet.2015.01.032.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver.
Nat Cell Biol. 2015 May 18. doi: 10.1038/ncb3169.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Adipocyte exosomes promote melanoma aggressiveness through fatty acid oxidation: a novel mechanism linking obesity and cancer.
Cancer Res. 2016 May 23. pii: canres.0651.2016.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Microvesicles provide a mechanism for intercellular communication by embryonic stem cells during embryo implantation.
Nat Commun. 2016 Jun 15;7:11958. doi: 10.1038/ncomms11958.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer.
Oncotarget. 2016 Aug 23. doi: 10.18632/oncotarget.11535.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer.
Oncotarget. 2016 Aug 23. doi: 10.18632/oncotarget.11535.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer.
Oncotarget. 2016 Aug 23. doi: 10.18632/oncotarget.11535.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Macrophage Foam Cell-Derived Extracellular Vesicles Promote Vascular Smooth Muscle Cell Migration and Adhesion.
J Am Heart Assoc. 2016 Oct 17;5(10). pii: e004099.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Macrophage Foam Cell-Derived Extracellular Vesicles Promote Vascular Smooth Muscle Cell Migration and Adhesion.
J Am Heart Assoc. 2016 Oct 17;5(10). pii: e004099.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Thymic exosomes promote the final maturation of thymocytes.
Sci Rep. 2016 Nov 8;6:36479. doi: 10.1038/srep36479.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity.
Cell. 2016 Dec 1;167(6):1525-1539.e17. doi: 10.1016/j.cell.2016.11.005.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity.
Cell. 2016 Dec 1;167(6):1525-1539.e17. doi: 10.1016/j.cell.2016.11.005.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Exploring experimental cerebral malaria pathogenesis through the characterisation of host-derived plasma microparticle protein content.
Sci Rep. 2016 Dec 5;6:37871. doi: 10.1038/srep37871.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Exploring experimental cerebral malaria pathogenesis through the characterisation of host-derived plasma microparticle protein content.
Sci Rep. 2016 Dec 5;6:37871. doi: 10.1038/srep37871.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Astrocyte-shed extracellular vesicles regulate the peripheral leukocyte response to inflammatory brain lesions.
Sci Signal. 2017 Apr 4;10(473). pii: eaai7696. doi: 10.1126/scisignal.aai7696.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Astrocyte-shed extracellular vesicles regulate the peripheral leukocyte response to inflammatory brain lesions.
Sci Signal. 2017 Apr 4;10(473). pii: eaai7696. doi: 10.1126/scisignal.aai7696.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Characterisation of adipocyte-derived extracellular vesicle subtypes identifies distinct protein and lipid signatures for large and small extracellular vesicles.
J Extracell Vesicles. 2017 Apr 10;6(1):1305677. doi: 10.1080/20013078.2017.1305677. eCollection 2017.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Characterisation of adipocyte-derived extracellular vesicle subtypes identifies distinct protein and lipid signatures for large and small extracellular vesicles.
J Extracell Vesicles. 2017 Apr 10;6(1):1305677. doi: 10.1080/20013078.2017.1305677. eCollection 2017.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Characterisation of adipocyte-derived extracellular vesicle subtypes identifies distinct protein and lipid signatures for large and small extracellular vesicles.
J Extracell Vesicles. 2017 Apr 10;6(1):1305677. doi: 10.1080/20013078.2017.1305677. eCollection 2017.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Hypoxia-induced changes in the fibroblast secretome, exosome, and whole-cell proteome using cultured, cardiac-derived cells isolated from neonatal mice.
J Proteome Res. 2017 Jun 22. doi: 10.1021/acs.jproteome.7b00144.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Hypoxia-induced changes in the fibroblast secretome, exosome, and whole-cell proteome using cultured, cardiac-derived cells isolated from neonatal mice.
J Proteome Res. 2017 Jun 22. doi: 10.1021/acs.jproteome.7b00144.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses.
J Extracell Vesicles. 2017 Aug 13;6(1):1359478. doi: 10.1080/20013078.2017.1359478. eCollection 2017.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses.
J Extracell Vesicles. 2017 Aug 13;6(1):1359478. doi: 10.1080/20013078.2017.1359478. eCollection 2017.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses.
J Extracell Vesicles. 2017 Aug 13;6(1):1359478. doi: 10.1080/20013078.2017.1359478. eCollection 2017.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Annexin-enriched osteoblast-derived vesicles act as an extracellular site of mineral nucleation within developing stem cell cultures.
Sci Rep. 2017 Oct 3;7(1):12639. doi: 10.1038/s41598-017-13027-6.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Annexin-enriched osteoblast-derived vesicles act as an extracellular site of mineral nucleation within developing stem cell cultures.
Sci Rep. 2017 Oct 3;7(1):12639. doi: 10.1038/s41598-017-13027-6.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Extracellular vesicles released by cardiomyocytes in a doxorubicin-induced cardiac injury mouse model contain protein biomarkers of early cardiac injury.
Clin Cancer Res. 2017 Oct 25. pii: clincanres.2046.2017. doi: 10.1158/1078-0432.CCR-17-2046.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Extracellular vesicles released by cardiomyocytes in a doxorubicin-induced cardiac injury mouse model contain protein biomarkers of early cardiac injury.
Clin Cancer Res. 2017 Oct 25. pii: clincanres.2046.2017. doi: 10.1158/1078-0432.CCR-17-2046.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.		ENOG410Y2NH401 / 0 / 401
Fibronectin (FN) [Cleaved into: Anastellin]P11276Exosomes as secondary inductive signals involved in kidney organogenesis.
J Extracell Vesicles. 2018 Jan 23;7(1):1422675. doi: 10.1080/20013078.2017.1422675. eCollection 2018.		ENOG410Y2NH401 / 0 / 401
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