This menu provides the list of EV proteins identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
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  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
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Protein name UniProt accession Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT).
Proteomics. 2012 Jan;12(2):329-38. doi: 10.1002/pmic.201100477. Epub 2011 Dec 16.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes.
Methods. 2012 Feb;56(2):293-304. doi: 10.1016/j.ymeth.2012.01.002. Epub 2012 Jan 21.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes.
Methods. 2012 Feb;56(2):293-304. doi: 10.1016/j.ymeth.2012.01.002. Epub 2012 Jan 21.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids.
Mol Cell Proteomics. 2013 Mar;12(3):587-98. doi: 10.1074/mcp.M112.021303. Epub 2012 Dec 10.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Characterization and proteomic analysis of ovarian cancer-derived exosomes.
J Proteomics. 2013 Jan 16;80C:171-182. doi: 10.1016/j.jprot.2012.12.029.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteome profiling of exosomes derived from human primary and metastatic colorectal cancer cells reveal differential expression of key metastatic factors and signal transduction components.
Proteomics. 2013 May;13(10-11):1672-86. doi: 10.1002/pmic.201200562.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Modulation of B-cell exosome proteins by gamma herpesvirus infection.
Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):E2925-33. doi: 10.1073/pnas.1303906110. Epub 2013 Jul 1.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Characterization of human thymic exosomes.
PLoS One. 2013 Jul 2;8(7):e67554. doi: 10.1371/journal.pone.0067554. Print 2013.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387LRRK2 secretion in exosomes is regulated by 14-3-3.
Hum Mol Genet. 2013 Dec 15;22(24):4988-5000. doi: 10.1093/hmg/ddt346. Epub 2013 Jul 25.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteome profiling of neuroblastoma-derived exosomes reveal the expression of proteins potentially involved in tumor progression.
PLoS One. 2013 Sep 19;8(9):e75054. doi: 10.1371/journal.pone.0075054. eCollection 2013.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.
J Extracell Vesicles. 2013 Dec 23;2. doi: 10.3402/jev.v2i0.22097. eCollection 2013.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.
J Extracell Vesicles. 2013 Dec 23;2. doi: 10.3402/jev.v2i0.22097. eCollection 2013.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential expression of EMT factors.
Proteomics. 2014 Mar;14(6):699-712. doi: 10.1002/pmic.201300452. Epub 2014 Feb 16.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential expression of EMT factors.
Proteomics. 2014 Mar;14(6):699-712. doi: 10.1002/pmic.201300452. Epub 2014 Feb 16.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential expression of EMT factors.
Proteomics. 2014 Mar;14(6):699-712. doi: 10.1002/pmic.201300452. Epub 2014 Feb 16.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.
Biochem Biophys Res Commun. 2014 Mar 21;445(4):694-701. doi: 10.1016/j.bbrc.2013.12.070. Epub 2014 Jan 14.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387The overexpression of a single oncogene (ERBB2/HER2) alters the proteomic landscape of extracellular vesicles.
Proteomics. 2014 Jun;14(12):1472-9. doi: 10.1002/pmic.201300485. Epub 2014 May 15.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387The overexpression of a single oncogene (ERBB2/HER2) alters the proteomic landscape of extracellular vesicles.
Proteomics. 2014 Jun;14(12):1472-9. doi: 10.1002/pmic.201300485. Epub 2014 May 15.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387The overexpression of a single oncogene (ERBB2/HER2) alters the proteomic landscape of extracellular vesicles.
Proteomics. 2014 Jun;14(12):1472-9. doi: 10.1002/pmic.201300485. Epub 2014 May 15.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh-7 Cells Using SILAC Labeling and LC-MS/MS.
J Proteome Res. 2014 Oct 8.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh-7 Cells Using SILAC Labeling and LC-MS/MS.
J Proteome Res. 2014 Oct 8.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh-7 Cells Using SILAC Labeling and LC-MS/MS.
J Proteome Res. 2014 Oct 8.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh-7 Cells Using SILAC Labeling and LC-MS/MS.
J Proteome Res. 2014 Oct 8.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic analysis of human placental syncytiotrophoblast microvesicles in preeclampsia.
Clin Proteomics. 2014 Nov 19;11(1):40. eCollection 2014.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens.
Immunol Cell Biol. 2015 Mar 17. doi: 10.1038/icb.2015.33.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Oncotarget. 2015 Mar 12.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Methods. 2015 Apr 16. pii: S1046-2023(15)00154-1. doi: 10.1016/j.ymeth.2015.04.008.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Methods. 2015 Apr 16. pii: S1046-2023(15)00154-1. doi: 10.1016/j.ymeth.2015.04.008.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Methods. 2015 Apr 16. pii: S1046-2023(15)00154-1. doi: 10.1016/j.ymeth.2015.04.008.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Methods. 2015 Apr 16. pii: S1046-2023(15)00154-1. doi: 10.1016/j.ymeth.2015.04.008.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes.
Oncotarget. 2015 Apr 12.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines.
Pigment Cell Melanoma Res. 2015 May 7. doi: 10.1111/pcmr.12380.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines.
Pigment Cell Melanoma Res. 2015 May 7. doi: 10.1111/pcmr.12380.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines.
Pigment Cell Melanoma Res. 2015 May 7. doi: 10.1111/pcmr.12380.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines.
Pigment Cell Melanoma Res. 2015 May 7. doi: 10.1111/pcmr.12380.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines.
Pigment Cell Melanoma Res. 2015 May 7. doi: 10.1111/pcmr.12380.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Microparticles released from Mycobacterium tuberculosis-infected human macrophages contain increased levels of the type I interferon inducible proteins including ISG15.
Proteomics. 2015 Jun 2. doi: 10.1002/pmic.201400610.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Ionizing radiation affects protein composition of exosomes secreted in vitro from head and neck squamous cell carcinoma.
Acta Biochim Pol. 2015;62(2):265-72. doi: 10.18388/abp.2015_970. Epub 2015 Jun 22.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Ionizing radiation affects protein composition of exosomes secreted in vitro from head and neck squamous cell carcinoma.
Acta Biochim Pol. 2015;62(2):265-72. doi: 10.18388/abp.2015_970. Epub 2015 Jun 22.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts.
Blood. 2015 Jun 22. pii: blood-2014-12-618025.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Exosomes as nanocarriers for systemic delivery of the Helicobacter pylori virulence factor CagA.
Sci Rep. 2016 Jan 7;6:18346. doi: 10.1038/srep18346.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Exosomes mediated pentose phosphate pathway in ovarian cancer metastasis: a proteomics analysis.
Int J Clin Exp Pathol. 2015 Dec 1;8(12):15719-28. eCollection 2015.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387ExtraPEG: a polyethylene glycol-based method for enrichment of extracellular vesicles.
Sci Rep. 2016 Apr 12;6:23978. doi: 10.1038/srep23978.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Effective isolation of exosomes with polyethylene glycol from cell culture supernatant for in-depth proteome profiling.
Analyst. 2016 May 27.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic Analysis of Exosomes and Exosome-Free Conditioned Media Derived from Human Osteosarcoma Cell Lines Reveal Differential Secretion of Proteins Related to Biological Functions and Tumor Progression.
J Cell Biochem. 2016 Jun 30. doi: 10.1002/jcb.25642.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic Analysis of Exosomes and Exosome-Free Conditioned Media Derived from Human Osteosarcoma Cell Lines Reveal Differential Secretion of Proteins Related to Biological Functions and Tumor Progression.
J Cell Biochem. 2016 Jun 30. doi: 10.1002/jcb.25642.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Efficient production and enhanced tumor delivery of engineered extracellular vesicles.
Biomaterials. 2016 Jul 6;105:195-205. doi: 10.1016/j.biomaterials.2016.07.003.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Efficient production and enhanced tumor delivery of engineered extracellular vesicles.
Biomaterials. 2016 Jul 6;105:195-205. doi: 10.1016/j.biomaterials.2016.07.003.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Secreted primary human malignant mesothelioma exosome signature reflects oncogenic cargo.
Sci Rep. 2016 Sep 8;6:32643. doi: 10.1038/srep32643.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Identification and Characterization of 293T Cell-Derived Exosomes by Profiling the Protein, mRNA and MicroRNA Components.
PLoS One. 2016 Sep 20;11(9):e0163043. doi: 10.1371/journal.pone.0163043. eCollection 2016.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Candida albicans Modifies the Protein Composition and Size Distribution of THP1 macrophages-derived Extracellular Vesicles.
J Proteome Res. 2016 Oct 14.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Candida albicans Modifies the Protein Composition and Size Distribution of THP1 macrophages-derived Extracellular Vesicles.
J Proteome Res. 2016 Oct 14.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Mycobacterium tuberculosis Infection Manipulates the Glycosylation Machinery and the N-Glycoproteome of Human Macrophages and their Microparticles.
J Proteome Res. 2016 Oct 19.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Mycobacterium tuberculosis Infection Manipulates the Glycosylation Machinery and the N-Glycoproteome of Human Macrophages and their Microparticles.
J Proteome Res. 2016 Oct 19.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources.
J Extracell Vesicles. 2016 Nov 17;5:32570. doi: 10.3402/jev.v5.32570. eCollection 2016.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources.
J Extracell Vesicles. 2016 Nov 17;5:32570. doi: 10.3402/jev.v5.32570. eCollection 2016.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources.
J Extracell Vesicles. 2016 Nov 17;5:32570. doi: 10.3402/jev.v5.32570. eCollection 2016.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Characterisation of extracellular vesicle-subsets derived from brain endothelial cells and analysis of their protein cargo modulation after TNF exposure.
J Extracell Vesicles. 2017 Apr 19;6(1):1302705. doi: 10.1080/20013078.2017.1302705. eCollection 2017.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Motile hepatocellular carcinoma cells preferentially secret sugar metabolism regulatory proteins via exosomes.
Proteomics. 2017 Jun 7. doi: 10.1002/pmic.201700103.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Motile hepatocellular carcinoma cells preferentially secret sugar metabolism regulatory proteins via exosomes.
Proteomics. 2017 Jun 7. doi: 10.1002/pmic.201700103.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Motile hepatocellular carcinoma cells preferentially secret sugar metabolism regulatory proteins via exosomes.
Proteomics. 2017 Jun 7. doi: 10.1002/pmic.201700103.		COG3569151 / 0 / 151
DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I)P11387Phytoagent Deoxyelephantopin and Its Derivative Inhibit Triple Negative Breast Cancer Cell Activity through ROS-Mediated Exosomal Activity and Protein Functions.
Front Pharmacol. 2017 Jun 29;8:398. doi: 10.3389/fphar.2017.00398. eCollection 2017.		COG3569151 / 0 / 151
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