This menu provides the list of EV proteins identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
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  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
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Protein name UniProt accession Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3)P21107Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.		ENOG410XR5K321 / 0 / 321
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3)P21107Exosomes from myeloid-derived suppressor cells carry biologically active proteins.
J Proteome Res. 2014 Feb 7;13(2):836-43. doi: 10.1021/pr400879c. Epub 2013 Dec 13.		ENOG410XR5K321 / 0 / 321
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3)P21107Exosomes from myeloid-derived suppressor cells carry biologically active proteins.
J Proteome Res. 2014 Feb 7;13(2):836-43. doi: 10.1021/pr400879c. Epub 2013 Dec 13.		ENOG410XR5K321 / 0 / 321
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3)P21107Circulating Extracellular Vesicles with Specific Proteome and Liver MicroRNAs Are Potential Biomarkers for Liver Injury in Experimental Fatty Liver Disease.
PLoS One. 2014 Dec 3;9(12):e113651. doi: 10.1371/journal.pone.0113651. eCollection 2014.		ENOG410XR5K321 / 0 / 321
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3)P21107A comprehensive proteomics analysis reveals a secretory path- and status-dependent signature of exosomes released from tumor associated macrophages.
J Proteome Res. 2015 Aug 27.		ENOG410XR5K321 / 0 / 321
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3)P21107A comprehensive proteomics analysis reveals a secretory path- and status-dependent signature of exosomes released from tumor associated macrophages.
J Proteome Res. 2015 Aug 27.		ENOG410XR5K321 / 0 / 321
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3)P21107Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.		ENOG410XR5K321 / 0 / 321
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3)P21107Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.		ENOG410XR5K321 / 0 / 321
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3)P21107Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.		ENOG410XR5K321 / 0 / 321
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3)P21107Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer.
Oncotarget. 2016 Aug 23. doi: 10.18632/oncotarget.11535.		ENOG410XR5K321 / 0 / 321
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3)P21107Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer.
Oncotarget. 2016 Aug 23. doi: 10.18632/oncotarget.11535.		ENOG410XR5K321 / 0 / 321
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3)P21107Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer.
Oncotarget. 2016 Aug 23. doi: 10.18632/oncotarget.11535.		ENOG410XR5K321 / 0 / 321
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3)P21107Mast Cell Degranulation Is Accompanied by the Release of a Selective Subset of Extracellular Vesicles That Contain Mast Cell-Specific Proteases.
J Immunol. 2016 Sep 12. pii: 1600614.		ENOG410XR5K321 / 0 / 321
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3)P21107Thymic exosomes promote the final maturation of thymocytes.
Sci Rep. 2016 Nov 8;6:36479. doi: 10.1038/srep36479.		ENOG410XR5K321 / 0 / 321
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3)P21107Hypoxia-induced changes in the fibroblast secretome, exosome, and whole-cell proteome using cultured, cardiac-derived cells isolated from neonatal mice.
J Proteome Res. 2017 Jun 22. doi: 10.1021/acs.jproteome.7b00144.		ENOG410XR5K321 / 0 / 321
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3)P21107Hypoxia-induced changes in the fibroblast secretome, exosome, and whole-cell proteome using cultured, cardiac-derived cells isolated from neonatal mice.
J Proteome Res. 2017 Jun 22. doi: 10.1021/acs.jproteome.7b00144.		ENOG410XR5K321 / 0 / 321
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3)P21107Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses.
J Extracell Vesicles. 2017 Aug 13;6(1):1359478. doi: 10.1080/20013078.2017.1359478. eCollection 2017.		ENOG410XR5K321 / 0 / 321
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3)P21107Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses.
J Extracell Vesicles. 2017 Aug 13;6(1):1359478. doi: 10.1080/20013078.2017.1359478. eCollection 2017.		ENOG410XR5K321 / 0 / 321
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3)P21107Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses.
J Extracell Vesicles. 2017 Aug 13;6(1):1359478. doi: 10.1080/20013078.2017.1359478. eCollection 2017.		ENOG410XR5K321 / 0 / 321
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3)P21107Increased Release of Apolipoprotein E in Extracellular Vesicles Following Amyloid-beta Protofibril Exposure of Neuroglial Co-Cultures.
J Alzheimers Dis. 2017 Aug 17. doi: 10.3233/JAD-170278.		ENOG410XR5K321 / 0 / 321
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3)P21107Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.		ENOG410XR5K321 / 0 / 321
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3)P21107Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.		ENOG410XR5K321 / 0 / 321
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3)P21107Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.		ENOG410XR5K321 / 0 / 321
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3)P21107Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.		ENOG410XR5K321 / 0 / 321
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3)P21107Differential content of proteins, mRNAs, and miRNAs suggests that MDSC and their exosomes may mediate distinct immune suppressive functions.
J Proteome Res. 2017 Nov 15. doi: 10.1021/acs.jproteome.7b00646.		ENOG410XR5K321 / 0 / 321
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3)P21107Differential content of proteins, mRNAs, and miRNAs suggests that MDSC and their exosomes may mediate distinct immune suppressive functions.
J Proteome Res. 2017 Nov 15. doi: 10.1021/acs.jproteome.7b00646.		ENOG410XR5K321 / 0 / 321
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