This menu provides the list of EV proteins identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
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  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
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Protein name UniProt accession Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteomic analysis of human prostasomes.
Prostate. 2003 Jul 1;56(2):150-61.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314The platelet microparticle proteome.
J Proteome Res. 2005 Sep-Oct;4(5):1516-21.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization.
Proteomics. 2006 Jan;6(1):153-71.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization.
Proteomics. 2006 Jan;6(1):153-71.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization.
Proteomics. 2006 Jan;6(1):153-71.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314The proteome of red cell membranes and vesicles during storage in blood bank conditions.
Transfusion. 2008 May;48(5):827-35.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314The proteome of red cell membranes and vesicles during storage in blood bank conditions.
Transfusion. 2008 May;48(5):827-35.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314The proteome of red cell membranes and vesicles during storage in blood bank conditions.
Transfusion. 2008 May;48(5):827-35.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles.
Proteomics. 2008 Jun;8(12):2430-46. doi: 10.1002/pmic.200701029.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles.
Proteomics. 2008 Jun;8(12):2430-46. doi: 10.1002/pmic.200701029.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles.
Proteomics. 2008 Jun;8(12):2430-46. doi: 10.1002/pmic.200701029.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Structural heterogeneity and protein composition of exosome-like vesicles (prostasomes) in human semen.
Prostate. 2009 Feb 1;69(2):159-67. doi: 10.1002/pros.20860.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Large-scale proteomics and phosphoproteomics of urinary exosomes.
J Am Soc Nephrol. 2009 Feb;20(2):363-79. doi: 10.1681/ASN.2008040406. Epub 2008 Dec 3.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Characterization of PKD protein-positive exosome-like vesicles.
J Am Soc Nephrol. 2009 Feb;20(2):278-88. doi: 10.1681/ASN.2008060564. Epub 2009 Jan 21.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
J Cell Physiol. 2009 Oct;221(1):221-31. doi: 10.1002/jcp.21847.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteomics analysis of A33 immunoaffinity-purified exosomes released from the human colon tumor cell line LIM1215 reveals a tissue-specific protein signature.
Mol Cell Proteomics. 2010 Feb;9(2):197-208. doi: 10.1074/mcp.M900152-MCP200. Epub 2009 Oct 16.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteomics analysis of A33 immunoaffinity-purified exosomes released from the human colon tumor cell line LIM1215 reveals a tissue-specific protein signature.
Mol Cell Proteomics. 2010 Feb;9(2):197-208. doi: 10.1074/mcp.M900152-MCP200. Epub 2009 Oct 16.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Mol Cell Proteomics. 2010 Jun;9(6):1085-99. doi: 10.1074/mcp.M900381-MCP200. Epub 2010 Feb 1.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteomics analysis of bladder cancer exosomes.
Mol Cell Proteomics. 2010 Jun;9(6):1324-38. doi: 10.1074/mcp.M000063-MCP201. Epub 2010 Mar 11.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Immunol Cell Biol. 2010 Nov-Dec;88(8):851-6. doi: 10.1038/icb.2010.64. Epub 2010 May 11.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Morphologic and proteomic characterization of exosomes released by cultured extravillous trophoblast cells.
Exp Cell Res. 2011 May 1;317(8):1192-202. doi: 10.1016/j.yexcr.2011.01.014. Epub 2011 Jan 26.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Protein profile of exosomes from trabecular meshwork cells.
J Proteomics. 2011 May 16;74(6):796-804. doi: 10.1016/j.jprot.2011.02.024. Epub 2011 Mar 8.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteomic characterization of biogenesis and functions of matrix vesicles released from mineralizing human osteoblast-like cells.
J Proteomics. 2011 Jun 10;74(7):1123-34. doi: 10.1016/j.jprot.2011.04.005. Epub 2011 Apr 15.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Expression of PTRF in PC-3 Cells modulates cholesterol dynamics and the actin cytoskeleton impacting secretion pathways.
Mol Cell Proteomics. 2012 Feb;11(2):M111.012245. doi: 10.1074/mcp.M111.012245. Epub 2011 Oct 26.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT).
Proteomics. 2012 Jan;12(2):329-38. doi: 10.1002/pmic.201100477. Epub 2011 Dec 16.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314The protein interaction network of extracellular vesicles derived from human colorectal cancer cells.
J Proteome Res. 2012 Feb 3;11(2):1144-51. doi: 10.1021/pr200842h. Epub 2012 Jan 9.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes.
Methods. 2012 Feb;56(2):293-304. doi: 10.1016/j.ymeth.2012.01.002. Epub 2012 Jan 21.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes.
Methods. 2012 Feb;56(2):293-304. doi: 10.1016/j.ymeth.2012.01.002. Epub 2012 Jan 21.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.
Nat Med. 2012 Jun;18(6):883-91. doi: 10.1038/nm.2753.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability.
J Proteomics. 2012 Jun 27;75(12):3574-84. doi: 10.1016/j.jprot.2012.03.054. Epub 2012 Apr 10.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability.
J Proteomics. 2012 Jun 27;75(12):3574-84. doi: 10.1016/j.jprot.2012.03.054. Epub 2012 Apr 10.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability.
J Proteomics. 2012 Jun 27;75(12):3574-84. doi: 10.1016/j.jprot.2012.03.054. Epub 2012 Apr 10.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Quantitative proteomic analysis of exosomes from HIV-1-infected lymphocytic cells.
Proteomics. 2012 Jul;12(13):2203-11. doi: 10.1002/pmic.201100376.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Quantitative proteomic analysis of exosomes from HIV-1-infected lymphocytic cells.
Proteomics. 2012 Jul;12(13):2203-11. doi: 10.1002/pmic.201100376.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteolytic Potential of the MSC Exosome Proteome: Implications for an Exosome-Mediated Delivery of Therapeutic Proteasome.
Int J Proteomics. 2012;2012:971907. doi: 10.1155/2012/971907. Epub 2012 Jul 18.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts.
J Proteomics. 2012 Dec 21;77:344-56. doi: 10.1016/j.jprot.2012.09.008. Epub 2012 Sep 20.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts.
J Proteomics. 2012 Dec 21;77:344-56. doi: 10.1016/j.jprot.2012.09.008. Epub 2012 Sep 20.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Cause or effect of arteriogenesis: compositional alterations of microparticles from CAD patients undergoing external counterpulsation therapy.
PLoS One. 2012;7(10):e46822. doi: 10.1371/journal.pone.0046822. Epub 2012 Oct 8.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Comparative and targeted proteomic analyses of urinary microparticles from bladder cancer and hernia patients.
J Proteome Res. 2012 Dec 7;11(12):5611-29. doi: 10.1021/pr3008732. Epub 2012 Oct 31.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Comparative and targeted proteomic analyses of urinary microparticles from bladder cancer and hernia patients.
J Proteome Res. 2012 Dec 7;11(12):5611-29. doi: 10.1021/pr3008732. Epub 2012 Oct 31.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Mol Cell Proteomics. 2013 Feb;12(2):343-55. doi: 10.1074/mcp.M112.022806. Epub 2012 Nov 15.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Mol Cell Proteomics. 2013 Feb;12(2):343-55. doi: 10.1074/mcp.M112.022806. Epub 2012 Nov 15.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Mol Cell Proteomics. 2013 Feb;12(2):343-55. doi: 10.1074/mcp.M112.022806. Epub 2012 Nov 15.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids.
Mol Cell Proteomics. 2013 Mar;12(3):587-98. doi: 10.1074/mcp.M112.021303. Epub 2012 Dec 10.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids.
Mol Cell Proteomics. 2013 Mar;12(3):587-98. doi: 10.1074/mcp.M112.021303. Epub 2012 Dec 10.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids.
Mol Cell Proteomics. 2013 Mar;12(3):587-98. doi: 10.1074/mcp.M112.021303. Epub 2012 Dec 10.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Characterization and proteomic analysis of ovarian cancer-derived exosomes.
J Proteomics. 2013 Jan 16;80C:171-182. doi: 10.1016/j.jprot.2012.12.029.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Characterization and proteomic analysis of ovarian cancer-derived exosomes.
J Proteomics. 2013 Jan 16;80C:171-182. doi: 10.1016/j.jprot.2012.12.029.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteomic analysis of podocyte exosome-enriched fraction from normal human urine.
J Proteomics. 2013 Apr 26;82:193-229. doi: 10.1016/j.jprot.2013.01.012. Epub 2013 Jan 30.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314A comprehensive characterization of membrane vesicles released by autophagic human endothelial cells.
Proteomics. 2013 Apr;13(7):1108-20. doi: 10.1002/pmic.201200531.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
Proteomics. 2013 May;13(10-11):1667-71. doi: 10.1002/pmic.201200561. Epub 2013 Apr 23.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
Proteomics. 2013 May;13(10-11):1667-71. doi: 10.1002/pmic.201200561. Epub 2013 Apr 23.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteome profiling of exosomes derived from human primary and metastatic colorectal cancer cells reveal differential expression of key metastatic factors and signal transduction components.
Proteomics. 2013 May;13(10-11):1672-86. doi: 10.1002/pmic.201200562.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteome profiling of exosomes derived from human primary and metastatic colorectal cancer cells reveal differential expression of key metastatic factors and signal transduction components.
Proteomics. 2013 May;13(10-11):1672-86. doi: 10.1002/pmic.201200562.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions.
Proteomics. 2013 Jul;13(14):2125-34. doi: 10.1002/pmic.201200323.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteomic characterization of human platelet-derived microparticles.
Anal Chim Acta. 2013 May 7;776:57-63. doi: 10.1016/j.aca.2013.03.023. Epub 2013 Mar 19.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties.
Mol Cell Proteomics. 2013 Aug;12(8):2205-19. doi: 10.1074/mcp.M113.028589. Epub 2013 May 8.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Malaria-infected erythrocyte-derived microvesicles mediate cellular communication within the parasite population and with the host immune system.
Cell Host Microbe. 2013 May 15;13(5):521-34. doi: 10.1016/j.chom.2013.04.009.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Modulation of B-cell exosome proteins by gamma herpesvirus infection.
Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):E2925-33. doi: 10.1073/pnas.1303906110. Epub 2013 Jul 1.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Characterization of human thymic exosomes.
PLoS One. 2013 Jul 2;8(7):e67554. doi: 10.1371/journal.pone.0067554. Print 2013.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Characterization of multiple myeloma vesicles by label-free relative quantitation.
Proteomics. 2013 Oct;13(20):3013-29. doi: 10.1002/pmic.201300142.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Characterization of multiple myeloma vesicles by label-free relative quantitation.
Proteomics. 2013 Oct;13(20):3013-29. doi: 10.1002/pmic.201300142.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells.
J Extracell Vesicles. 2012 Sep 11;1. doi: 10.3402/jev.v1i0.18704. eCollection 2012.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells.
J Extracell Vesicles. 2012 Sep 11;1. doi: 10.3402/jev.v1i0.18704. eCollection 2012.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes.
J Extracell Vesicles. 2012 Apr 16;1. doi: 10.3402/jev.v1i0.18396. eCollection 2012.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.
J Extracell Vesicles. 2013 Dec 23;2. doi: 10.3402/jev.v2i0.22097. eCollection 2013.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.
J Extracell Vesicles. 2013 Dec 23;2. doi: 10.3402/jev.v2i0.22097. eCollection 2013.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential expression of EMT factors.
Proteomics. 2014 Mar;14(6):699-712. doi: 10.1002/pmic.201300452. Epub 2014 Feb 16.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential expression of EMT factors.
Proteomics. 2014 Mar;14(6):699-712. doi: 10.1002/pmic.201300452. Epub 2014 Feb 16.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential expression of EMT factors.
Proteomics. 2014 Mar;14(6):699-712. doi: 10.1002/pmic.201300452. Epub 2014 Feb 16.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.
Biochem Biophys Res Commun. 2014 Mar 21;445(4):694-701. doi: 10.1016/j.bbrc.2013.12.070. Epub 2014 Jan 14.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Molecular characterization of exosome-like vesicles from breast cancer cells.
BMC Cancer. 2014 Jan 27;14:44. doi: 10.1186/1471-2407-14-44.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Plasma biomarker discovery in preeclampsia using a novel differential isolation technology for circulating extracellular vesicles.
Am J Obstet Gynecol. 2014 Mar 18. pii: S0002-9378(14)00248-8. doi: 10.1016/j.ajog.2014.03.038.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteomic analysis of hypoxia-induced U373MG glioma secretome reveals novel hypoxia-dependent migration factors.
Proteomics. 2014 Jun;14(12):1494-502. doi: 10.1002/pmic.201300554. Epub 2014 May 16.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteomic analysis of hypoxia-induced U373MG glioma secretome reveals novel hypoxia-dependent migration factors.
Proteomics. 2014 Jun;14(12):1494-502. doi: 10.1002/pmic.201300554. Epub 2014 May 16.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314The overexpression of a single oncogene (ERBB2/HER2) alters the proteomic landscape of extracellular vesicles.
Proteomics. 2014 Jun;14(12):1472-9. doi: 10.1002/pmic.201300485. Epub 2014 May 15.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314The overexpression of a single oncogene (ERBB2/HER2) alters the proteomic landscape of extracellular vesicles.
Proteomics. 2014 Jun;14(12):1472-9. doi: 10.1002/pmic.201300485. Epub 2014 May 15.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314The overexpression of a single oncogene (ERBB2/HER2) alters the proteomic landscape of extracellular vesicles.
Proteomics. 2014 Jun;14(12):1472-9. doi: 10.1002/pmic.201300485. Epub 2014 May 15.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314The overexpression of a single oncogene (ERBB2/HER2) alters the proteomic landscape of extracellular vesicles.
Proteomics. 2014 Jun;14(12):1472-9. doi: 10.1002/pmic.201300485. Epub 2014 May 15.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteomic analysis of cerebrospinal fluid extracellular vesicles: a comprehensive dataset.
J Proteomics. 2014 Jun 25;106:191-204. doi: 10.1016/j.jprot.2014.04.028. Epub 2014 Apr 24.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Human T-lymphotropic Virus Type 1-infected Cells Secrete Exosomes That Contain Tax Protein.
J Biol Chem. 2014 Aug 8;289(32):22284-305. doi: 10.1074/jbc.M114.549659. Epub 2014 Jun 17.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Human T-lymphotropic Virus Type 1-infected Cells Secrete Exosomes That Contain Tax Protein.
J Biol Chem. 2014 Aug 8;289(32):22284-305. doi: 10.1074/jbc.M114.549659. Epub 2014 Jun 17.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets.
Transfusion. 2014 Oct 21. doi: 10.1111/trf.12874.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets.
Transfusion. 2014 Oct 21. doi: 10.1111/trf.12874.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314A New Workflow for Proteomic Analysis of Urinary Exosomes and Assessment in Cystinuria Patients.
J Proteome Res. 2014 Nov 12.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314A New Workflow for Proteomic Analysis of Urinary Exosomes and Assessment in Cystinuria Patients.
J Proteome Res. 2014 Nov 12.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Intraluminal proteome and peptidome of human urinary extracellular vesicles.
Proteomics Clin Appl. 2014 Dec 4. doi: 10.1002/prca.201400085.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens.
Immunol Cell Biol. 2015 Mar 17. doi: 10.1038/icb.2015.33.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Exosomes released from breast cancer carcinomas stimulate cell movement.
PLoS One. 2015 Mar 23;10(3):e0117495. doi: 10.1371/journal.pone.0117495. eCollection 2015.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Methods. 2015 Apr 16. pii: S1046-2023(15)00154-1. doi: 10.1016/j.ymeth.2015.04.008.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Methods. 2015 Apr 16. pii: S1046-2023(15)00154-1. doi: 10.1016/j.ymeth.2015.04.008.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Methods. 2015 Apr 16. pii: S1046-2023(15)00154-1. doi: 10.1016/j.ymeth.2015.04.008.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Methods. 2015 Apr 16. pii: S1046-2023(15)00154-1. doi: 10.1016/j.ymeth.2015.04.008.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes.
Oncotarget. 2015 Apr 12.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes.
Oncotarget. 2015 Apr 12.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines.
Pigment Cell Melanoma Res. 2015 May 7. doi: 10.1111/pcmr.12380.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines.
Pigment Cell Melanoma Res. 2015 May 7. doi: 10.1111/pcmr.12380.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines.
Pigment Cell Melanoma Res. 2015 May 7. doi: 10.1111/pcmr.12380.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines.
Pigment Cell Melanoma Res. 2015 May 7. doi: 10.1111/pcmr.12380.		COG0476375 / 0 / 375
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1)P22314Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines.
Pigment Cell Melanoma Res. 2015 May 7. doi: 10.1111/pcmr.12380.		COG0476375 / 0 / 375
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