This menu provides the list of EV proteins identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
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  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
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Protein name UniProt accession Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694The platelet microparticle proteome.
J Proteome Res. 2005 Sep-Oct;4(5):1516-21.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic analysis of malignant lymphocyte membrane microparticles using double ionization coverage optimization.
Proteomics. 2006 Jan;6(1):153-71.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT).
Proteomics. 2012 Jan;12(2):329-38. doi: 10.1002/pmic.201100477. Epub 2011 Dec 16.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability.
J Proteomics. 2012 Jun 27;75(12):3574-84. doi: 10.1016/j.jprot.2012.03.054. Epub 2012 Apr 10.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability.
J Proteomics. 2012 Jun 27;75(12):3574-84. doi: 10.1016/j.jprot.2012.03.054. Epub 2012 Apr 10.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Cause or effect of arteriogenesis: compositional alterations of microparticles from CAD patients undergoing external counterpulsation therapy.
PLoS One. 2012;7(10):e46822. doi: 10.1371/journal.pone.0046822. Epub 2012 Oct 8.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Characterization and proteomic analysis of ovarian cancer-derived exosomes.
J Proteomics. 2013 Jan 16;80C:171-182. doi: 10.1016/j.jprot.2012.12.029.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic analysis of podocyte exosome-enriched fraction from normal human urine.
J Proteomics. 2013 Apr 26;82:193-229. doi: 10.1016/j.jprot.2013.01.012. Epub 2013 Jan 30.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic characterization of human platelet-derived microparticles.
Anal Chim Acta. 2013 May 7;776:57-63. doi: 10.1016/j.aca.2013.03.023. Epub 2013 Mar 19.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Characterization of human thymic exosomes.
PLoS One. 2013 Jul 2;8(7):e67554. doi: 10.1371/journal.pone.0067554. Print 2013.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteome profiling of neuroblastoma-derived exosomes reveal the expression of proteins potentially involved in tumor progression.
PLoS One. 2013 Sep 19;8(9):e75054. doi: 10.1371/journal.pone.0075054. eCollection 2013.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets.
Transfusion. 2014 Oct 21. doi: 10.1111/trf.12874.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets.
Transfusion. 2014 Oct 21. doi: 10.1111/trf.12874.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Intraluminal proteome and peptidome of human urinary extracellular vesicles.
Proteomics Clin Appl. 2014 Dec 4. doi: 10.1002/prca.201400085.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Exosomes released from breast cancer carcinomas stimulate cell movement.
PLoS One. 2015 Mar 23;10(3):e0117495. doi: 10.1371/journal.pone.0117495. eCollection 2015.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes.
Oncotarget. 2015 Apr 12.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes.
Oncotarget. 2015 Apr 12.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes.
Proc Natl Acad Sci U S A. 2016 Feb 8. pii: 201521230.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes.
Proc Natl Acad Sci U S A. 2016 Feb 8. pii: 201521230.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Enrichment of extracellular vesicles from tissues of the central nervous system by PROSPR.
Mol Neurodegener. 2016 May 23;11(1):41. doi: 10.1186/s13024-016-0108-1.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Effective isolation of exosomes with polyethylene glycol from cell culture supernatant for in-depth proteome profiling.
Analyst. 2016 May 27.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic Analysis of Exosomes and Exosome-Free Conditioned Media Derived from Human Osteosarcoma Cell Lines Reveal Differential Secretion of Proteins Related to Biological Functions and Tumor Progression.
J Cell Biochem. 2016 Jun 30. doi: 10.1002/jcb.25642.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic Analysis of Exosomes and Exosome-Free Conditioned Media Derived from Human Osteosarcoma Cell Lines Reveal Differential Secretion of Proteins Related to Biological Functions and Tumor Progression.
J Cell Biochem. 2016 Jun 30. doi: 10.1002/jcb.25642.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Secreted primary human malignant mesothelioma exosome signature reflects oncogenic cargo.
Sci Rep. 2016 Sep 8;6:32643. doi: 10.1038/srep32643.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Secreted primary human malignant mesothelioma exosome signature reflects oncogenic cargo.
Sci Rep. 2016 Sep 8;6:32643. doi: 10.1038/srep32643.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Identification and Characterization of 293T Cell-Derived Exosomes by Profiling the Protein, mRNA and MicroRNA Components.
PLoS One. 2016 Sep 20;11(9):e0163043. doi: 10.1371/journal.pone.0163043. eCollection 2016.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic and bioinformatic characterization of extracellular vesicles released from human macrophages upon influenza A virus infection.
J Proteome Res. 2016 Oct 11.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic and bioinformatic characterization of extracellular vesicles released from human macrophages upon influenza A virus infection.
J Proteome Res. 2016 Oct 11.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic analysis of urinary extracellular vesicles from high Gleason score prostate cancer.
Sci Rep. 2017 Feb 17;7:42961. doi: 10.1038/srep42961.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic analysis of urinary extracellular vesicles from high Gleason score prostate cancer.
Sci Rep. 2017 Feb 17;7:42961. doi: 10.1038/srep42961.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Proteomic analysis of urinary extracellular vesicles from high Gleason score prostate cancer.
Sci Rep. 2017 Feb 17;7:42961. doi: 10.1038/srep42961.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Small extracellular vesicles secreted from senescent cells promote cancer cell proliferation through EphA2.
Nat Commun. 2017 Jun 6;8:15729. doi: 10.1038/ncomms15728.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Multiple extracellular vesicle types in peritoneal dialysis effluent are prominent and contain known biomarkers.
PLoS One. 2017 Jun 8;12(6):e0178601. doi: 10.1371/journal.pone.0178601. eCollection 2017.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Multiple extracellular vesicle types in peritoneal dialysis effluent are prominent and contain known biomarkers.
PLoS One. 2017 Jun 8;12(6):e0178601. doi: 10.1371/journal.pone.0178601. eCollection 2017.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Feasibility of urinary extracellular vesicle proteome profiling using a robust and simple, clinically applicable isolation method.
J Extracell Vesicles. 2017 Apr 28;6(1):1313091. doi: 10.1080/20013078.2017.1313091. eCollection 2017.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Insulin mediated activation of PI3K/Akt signalling pathway modifies the proteomic cargo of extracellular vesicles.
Proteomics. 2017 Aug 26. doi: 10.1002/pmic.201600371.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Comprehensive proteomics analysis of exosomes derived from human seminal plasma.
Andrology. 2017 Sep;5(5):1007-1015. doi: 10.1111/andr.12412.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Quantitation of putative colorectal cancer biomarker candidates in serum extracellular vesicles by targeted proteomics.
Sci Rep. 2017 Oct 6;7(1):12782. doi: 10.1038/s41598-017-13092-x.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Quantitation of putative colorectal cancer biomarker candidates in serum extracellular vesicles by targeted proteomics.
Sci Rep. 2017 Oct 6;7(1):12782. doi: 10.1038/s41598-017-13092-x.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Hepatic stellate cell-derived PDGFRalpha-enriched extracellular vesicles promote liver fibrosis in mice through SHP2.
Hepatology. 2018 Jan 23. doi: 10.1002/hep.29803.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Hepatic stellate cell-derived PDGFRalpha-enriched extracellular vesicles promote liver fibrosis in mice through SHP2.
Hepatology. 2018 Jan 23. doi: 10.1002/hep.29803.
ENOG410XPQQ158 / 0 / 158
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)P22694Hepatic stellate cell-derived PDGFRalpha-enriched extracellular vesicles promote liver fibrosis in mice through SHP2.
Hepatology. 2018 Jan 23. doi: 10.1002/hep.29803.
ENOG410XPQQ158 / 0 / 158
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