This menu provides the list of EV proteins identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
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  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
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Protein name UniProt accession Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
Thrombospondin-1P35441Cells release prions in association with exosomes.
Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9683-8. Epub 2004 Jun 21.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis.
PLoS Negl Trop Dis. 2013 May 2;7(5):e2185. doi: 10.1371/journal.pntd.0002185. Print 2013.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis.
PLoS Negl Trop Dis. 2013 May 2;7(5):e2185. doi: 10.1371/journal.pntd.0002185. Print 2013.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis.
PLoS Negl Trop Dis. 2013 May 2;7(5):e2185. doi: 10.1371/journal.pntd.0002185. Print 2013.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441Exosomes from myeloid-derived suppressor cells carry biologically active proteins.
J Proteome Res. 2014 Feb 7;13(2):836-43. doi: 10.1021/pr400879c. Epub 2013 Dec 13.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441Exosomes from myeloid-derived suppressor cells carry biologically active proteins.
J Proteome Res. 2014 Feb 7;13(2):836-43. doi: 10.1021/pr400879c. Epub 2013 Dec 13.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441Membrane microvesicles as mediators for melanoma-fibroblasts communication: Roles of the VCAM-1/VLA-4 axis and the ERK1/2 signal pathway.
Cancer Lett. 2015 Feb 4. pii: S0304-3835(15)00066-X. doi: 10.1016/j.canlet.2015.01.032.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver.
Nat Cell Biol. 2015 May 18. doi: 10.1038/ncb3169.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441A comprehensive proteomics analysis reveals a secretory path- and status-dependent signature of exosomes released from tumor associated macrophages.
J Proteome Res. 2015 Aug 27.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441A comprehensive proteomics analysis reveals a secretory path- and status-dependent signature of exosomes released from tumor associated macrophages.
J Proteome Res. 2015 Aug 27.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441Adipocyte exosomes promote melanoma aggressiveness through fatty acid oxidation: a novel mechanism linking obesity and cancer.
Cancer Res. 2016 May 23. pii: canres.0651.2016.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer.
Oncotarget. 2016 Aug 23. doi: 10.18632/oncotarget.11535.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer.
Oncotarget. 2016 Aug 23. doi: 10.18632/oncotarget.11535.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer.
Oncotarget. 2016 Aug 23. doi: 10.18632/oncotarget.11535.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441Macrophage Foam Cell-Derived Extracellular Vesicles Promote Vascular Smooth Muscle Cell Migration and Adhesion.
J Am Heart Assoc. 2016 Oct 17;5(10). pii: e004099.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441Macrophage Foam Cell-Derived Extracellular Vesicles Promote Vascular Smooth Muscle Cell Migration and Adhesion.
J Am Heart Assoc. 2016 Oct 17;5(10). pii: e004099.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441Exploring experimental cerebral malaria pathogenesis through the characterisation of host-derived plasma microparticle protein content.
Sci Rep. 2016 Dec 5;6:37871. doi: 10.1038/srep37871.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441Hypoxia-induced changes in the fibroblast secretome, exosome, and whole-cell proteome using cultured, cardiac-derived cells isolated from neonatal mice.
J Proteome Res. 2017 Jun 22. doi: 10.1021/acs.jproteome.7b00144.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441Hypoxia-induced changes in the fibroblast secretome, exosome, and whole-cell proteome using cultured, cardiac-derived cells isolated from neonatal mice.
J Proteome Res. 2017 Jun 22. doi: 10.1021/acs.jproteome.7b00144.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses.
J Extracell Vesicles. 2017 Aug 13;6(1):1359478. doi: 10.1080/20013078.2017.1359478. eCollection 2017.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses.
J Extracell Vesicles. 2017 Aug 13;6(1):1359478. doi: 10.1080/20013078.2017.1359478. eCollection 2017.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses.
J Extracell Vesicles. 2017 Aug 13;6(1):1359478. doi: 10.1080/20013078.2017.1359478. eCollection 2017.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441Increased Release of Apolipoprotein E in Extracellular Vesicles Following Amyloid-beta Protofibril Exposure of Neuroglial Co-Cultures.
J Alzheimers Dis. 2017 Aug 17. doi: 10.3233/JAD-170278.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441Extracellular vesicles released by cardiomyocytes in a doxorubicin-induced cardiac injury mouse model contain protein biomarkers of early cardiac injury.
Clin Cancer Res. 2017 Oct 25. pii: clincanres.2046.2017. doi: 10.1158/1078-0432.CCR-17-2046.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441Extracellular vesicles released by cardiomyocytes in a doxorubicin-induced cardiac injury mouse model contain protein biomarkers of early cardiac injury.
Clin Cancer Res. 2017 Oct 25. pii: clincanres.2046.2017. doi: 10.1158/1078-0432.CCR-17-2046.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441Differential content of proteins, mRNAs, and miRNAs suggests that MDSC and their exosomes may mediate distinct immune suppressive functions.
J Proteome Res. 2017 Nov 15. doi: 10.1021/acs.jproteome.7b00646.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441Differential content of proteins, mRNAs, and miRNAs suggests that MDSC and their exosomes may mediate distinct immune suppressive functions.
J Proteome Res. 2017 Nov 15. doi: 10.1021/acs.jproteome.7b00646.		ENOG410XQKE360 / 0 / 360
Thrombospondin-1P35441Exosomes as secondary inductive signals involved in kidney organogenesis.
J Extracell Vesicles. 2018 Jan 23;7(1):1422675. doi: 10.1080/20013078.2017.1422675. eCollection 2018.		ENOG410XQKE360 / 0 / 360
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