This menu provides the list of EV proteins identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
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  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
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Protein name UniProt accession Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)P39688Proteomic analysis of C2C12 myoblast and myotube exosome-like vesicles: a new paradigm for myoblast-myotube cross talk?
PLoS One. 2014 Jan 2;9(1):e84153. doi: 10.1371/journal.pone.0084153. eCollection 2014.		COG0515429 / 10 / 419
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)P39688Extracellular Vesicles from Neural Stem Cells Transfer IFN-gamma via Ifngr1 to Activate Stat1 Signaling in Target Cells.
Mol Cell. 2014 Sep 16. pii: S1097-2765(14)00675-3. doi: 10.1016/j.molcel.2014.08.020.		COG0515429 / 10 / 419
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)P39688Extracellular Vesicles from Neural Stem Cells Transfer IFN-gamma via Ifngr1 to Activate Stat1 Signaling in Target Cells.
Mol Cell. 2014 Sep 16. pii: S1097-2765(14)00675-3. doi: 10.1016/j.molcel.2014.08.020.		COG0515429 / 10 / 419
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)P39688Membrane microvesicles as mediators for melanoma-fibroblasts communication: Roles of the VCAM-1/VLA-4 axis and the ERK1/2 signal pathway.
Cancer Lett. 2015 Feb 4. pii: S0304-3835(15)00066-X. doi: 10.1016/j.canlet.2015.01.032.		COG0515429 / 10 / 419
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)P39688A comprehensive proteomics analysis reveals a secretory path- and status-dependent signature of exosomes released from tumor associated macrophages.
J Proteome Res. 2015 Aug 27.		COG0515429 / 10 / 419
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)P39688A comprehensive proteomics analysis reveals a secretory path- and status-dependent signature of exosomes released from tumor associated macrophages.
J Proteome Res. 2015 Aug 27.		COG0515429 / 10 / 419
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)P39688Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.		COG0515429 / 10 / 419
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)P39688Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.		COG0515429 / 10 / 419
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)P39688Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.		COG0515429 / 10 / 419
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)P39688Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer.
Oncotarget. 2016 Aug 23. doi: 10.18632/oncotarget.11535.		COG0515429 / 10 / 419
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)P39688Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer.
Oncotarget. 2016 Aug 23. doi: 10.18632/oncotarget.11535.		COG0515429 / 10 / 419
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)P39688Secreted Glioblastoma Nanovesicles Contain Intracellular Signaling Proteins and Active Ras Incorporated in a Farnesylation-dependent Manner.
J Biol Chem. 2016 Dec 1. pii: jbc.M116.747618.		COG0515429 / 10 / 419
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)P39688The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity.
Cell. 2016 Dec 1;167(6):1525-1539.e17. doi: 10.1016/j.cell.2016.11.005.		COG0515429 / 10 / 419
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)P39688The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity.
Cell. 2016 Dec 1;167(6):1525-1539.e17. doi: 10.1016/j.cell.2016.11.005.		COG0515429 / 10 / 419
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)P39688Hypoxia-induced changes in the fibroblast secretome, exosome, and whole-cell proteome using cultured, cardiac-derived cells isolated from neonatal mice.
J Proteome Res. 2017 Jun 22. doi: 10.1021/acs.jproteome.7b00144.		COG0515429 / 10 / 419
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)P39688Hypoxia-induced changes in the fibroblast secretome, exosome, and whole-cell proteome using cultured, cardiac-derived cells isolated from neonatal mice.
J Proteome Res. 2017 Jun 22. doi: 10.1021/acs.jproteome.7b00144.		COG0515429 / 10 / 419
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)P39688Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses.
J Extracell Vesicles. 2017 Aug 13;6(1):1359478. doi: 10.1080/20013078.2017.1359478. eCollection 2017.		COG0515429 / 10 / 419
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)P39688Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses.
J Extracell Vesicles. 2017 Aug 13;6(1):1359478. doi: 10.1080/20013078.2017.1359478. eCollection 2017.		COG0515429 / 10 / 419
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)P39688Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses.
J Extracell Vesicles. 2017 Aug 13;6(1):1359478. doi: 10.1080/20013078.2017.1359478. eCollection 2017.		COG0515429 / 10 / 419
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)P39688Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.		COG0515429 / 10 / 419
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)P39688Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.		COG0515429 / 10 / 419
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)P39688Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.		COG0515429 / 10 / 419
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)P39688Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.		COG0515429 / 10 / 419
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