This menu provides the list of EV proteins identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
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  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
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Protein name UniProt accession Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?
Proteomics Clin Appl. 2007 Nov;1(11):1446-61. doi: 10.1002/prca.200700522. Epub 2007 Oct 16.		COG3869230 / 0 / 230
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447Extracellular Vesicles from Neural Stem Cells Transfer IFN-gamma via Ifngr1 to Activate Stat1 Signaling in Target Cells.
Mol Cell. 2014 Sep 16. pii: S1097-2765(14)00675-3. doi: 10.1016/j.molcel.2014.08.020.		COG3869230 / 0 / 230
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447Extracellular Vesicles from Neural Stem Cells Transfer IFN-gamma via Ifngr1 to Activate Stat1 Signaling in Target Cells.
Mol Cell. 2014 Sep 16. pii: S1097-2765(14)00675-3. doi: 10.1016/j.molcel.2014.08.020.		COG3869230 / 0 / 230
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447Membrane microvesicles as mediators for melanoma-fibroblasts communication: Roles of the VCAM-1/VLA-4 axis and the ERK1/2 signal pathway.
Cancer Lett. 2015 Feb 4. pii: S0304-3835(15)00066-X. doi: 10.1016/j.canlet.2015.01.032.		COG3869230 / 0 / 230
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver.
Nat Cell Biol. 2015 May 18. doi: 10.1038/ncb3169.		COG3869230 / 0 / 230
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447A comprehensive proteomics analysis reveals a secretory path- and status-dependent signature of exosomes released from tumor associated macrophages.
J Proteome Res. 2015 Aug 27.		COG3869230 / 0 / 230
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447A comprehensive proteomics analysis reveals a secretory path- and status-dependent signature of exosomes released from tumor associated macrophages.
J Proteome Res. 2015 Aug 27.		COG3869230 / 0 / 230
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.		COG3869230 / 0 / 230
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.		COG3869230 / 0 / 230
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.		COG3869230 / 0 / 230
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447Enrichment of extracellular vesicles from tissues of the central nervous system by PROSPR.
Mol Neurodegener. 2016 May 23;11(1):41. doi: 10.1186/s13024-016-0108-1.		COG3869230 / 0 / 230
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447Microvesicles provide a mechanism for intercellular communication by embryonic stem cells during embryo implantation.
Nat Commun. 2016 Jun 15;7:11958. doi: 10.1038/ncomms11958.		COG3869230 / 0 / 230
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447Procoagulant and immunogenic properties of melanoma exosomes, microvesicles and apoptotic vesicles.
Oncotarget. 2016 Jul 22. doi: 10.18632/oncotarget.10783.		COG3869230 / 0 / 230
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447Procoagulant and immunogenic properties of melanoma exosomes, microvesicles and apoptotic vesicles.
Oncotarget. 2016 Jul 22. doi: 10.18632/oncotarget.10783.		COG3869230 / 0 / 230
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer.
Oncotarget. 2016 Aug 23. doi: 10.18632/oncotarget.11535.		COG3869230 / 0 / 230
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447Macrophage Foam Cell-Derived Extracellular Vesicles Promote Vascular Smooth Muscle Cell Migration and Adhesion.
J Am Heart Assoc. 2016 Oct 17;5(10). pii: e004099.		COG3869230 / 0 / 230
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447Secreted Glioblastoma Nanovesicles Contain Intracellular Signaling Proteins and Active Ras Incorporated in a Farnesylation-dependent Manner.
J Biol Chem. 2016 Dec 1. pii: jbc.M116.747618.		COG3869230 / 0 / 230
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity.
Cell. 2016 Dec 1;167(6):1525-1539.e17. doi: 10.1016/j.cell.2016.11.005.		COG3869230 / 0 / 230
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity.
Cell. 2016 Dec 1;167(6):1525-1539.e17. doi: 10.1016/j.cell.2016.11.005.		COG3869230 / 0 / 230
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447Astrocyte-shed extracellular vesicles regulate the peripheral leukocyte response to inflammatory brain lesions.
Sci Signal. 2017 Apr 4;10(473). pii: eaai7696. doi: 10.1126/scisignal.aai7696.		COG3869230 / 0 / 230
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447Astrocyte-shed extracellular vesicles regulate the peripheral leukocyte response to inflammatory brain lesions.
Sci Signal. 2017 Apr 4;10(473). pii: eaai7696. doi: 10.1126/scisignal.aai7696.		COG3869230 / 0 / 230
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447Hypoxia-induced changes in the fibroblast secretome, exosome, and whole-cell proteome using cultured, cardiac-derived cells isolated from neonatal mice.
J Proteome Res. 2017 Jun 22. doi: 10.1021/acs.jproteome.7b00144.		COG3869230 / 0 / 230
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447Hypoxia-induced changes in the fibroblast secretome, exosome, and whole-cell proteome using cultured, cardiac-derived cells isolated from neonatal mice.
J Proteome Res. 2017 Jun 22. doi: 10.1021/acs.jproteome.7b00144.		COG3869230 / 0 / 230
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447Increased Release of Apolipoprotein E in Extracellular Vesicles Following Amyloid-beta Protofibril Exposure of Neuroglial Co-Cultures.
J Alzheimers Dis. 2017 Aug 17. doi: 10.3233/JAD-170278.		COG3869230 / 0 / 230
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.		COG3869230 / 0 / 230
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.		COG3869230 / 0 / 230
Creatine kinase B-type (EC 2.7.3.2) (B-CK) (Creatine kinase B chain)Q04447Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.		COG3869230 / 0 / 230
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