This menu provides the list of EV proteins identified by high-throughput analyses.

Search:
Superdomain: All Prokaryote Eukaryote
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  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
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Protein name UniProt accession Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT).
Proteomics. 2012 Jan;12(2):329-38. doi: 10.1002/pmic.201100477. Epub 2011 Dec 16.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Characterization and proteomic analysis of ovarian cancer-derived exosomes.
J Proteomics. 2013 Jan 16;80C:171-182. doi: 10.1016/j.jprot.2012.12.029.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Characterization and proteomic analysis of ovarian cancer-derived exosomes.
J Proteomics. 2013 Jan 16;80C:171-182. doi: 10.1016/j.jprot.2012.12.029.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.
J Extracell Vesicles. 2013 Dec 23;2. doi: 10.3402/jev.v2i0.22097. eCollection 2013.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.
J Extracell Vesicles. 2013 Dec 23;2. doi: 10.3402/jev.v2i0.22097. eCollection 2013.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets.
Transfusion. 2014 Oct 21. doi: 10.1111/trf.12874.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91A New Workflow for Proteomic Analysis of Urinary Exosomes and Assessment in Cystinuria Patients.
J Proteome Res. 2014 Nov 12.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes.
Oncotarget. 2015 Apr 12.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Microparticles released from Mycobacterium tuberculosis-infected human macrophages contain increased levels of the type I interferon inducible proteins including ISG15.
Proteomics. 2015 Jun 2. doi: 10.1002/pmic.201400610.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Exosomes mediated pentose phosphate pathway in ovarian cancer metastasis: a proteomics analysis.
Int J Clin Exp Pathol. 2015 Dec 1;8(12):15719-28. eCollection 2015.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Exosomes mediated pentose phosphate pathway in ovarian cancer metastasis: a proteomics analysis.
Int J Clin Exp Pathol. 2015 Dec 1;8(12):15719-28. eCollection 2015.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91MSC secretes at least 3 EV types each with a unique permutation of membrane lipid, protein and RNA.
J Extracell Vesicles. 2016 Feb 24;5:29828. doi: 10.3402/jev.v5.29828. eCollection 2016.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic Analysis of Exosomes and Exosome-Free Conditioned Media Derived from Human Osteosarcoma Cell Lines Reveal Differential Secretion of Proteins Related to Biological Functions and Tumor Progression.
J Cell Biochem. 2016 Jun 30. doi: 10.1002/jcb.25642.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Efficient production and enhanced tumor delivery of engineered extracellular vesicles.
Biomaterials. 2016 Jul 6;105:195-205. doi: 10.1016/j.biomaterials.2016.07.003.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Efficient production and enhanced tumor delivery of engineered extracellular vesicles.
Biomaterials. 2016 Jul 6;105:195-205. doi: 10.1016/j.biomaterials.2016.07.003.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Identification and Characterization of 293T Cell-Derived Exosomes by Profiling the Protein, mRNA and MicroRNA Components.
PLoS One. 2016 Sep 20;11(9):e0163043. doi: 10.1371/journal.pone.0163043. eCollection 2016.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Extracellular vesicles as a source for non-invasive biomarkers in bladder cancer progression.
Eur J Pharm Sci. 2016 Oct 14. pii: S0928-0987(16)30431-6. doi: 10.1016/j.ejps.2016.10.008.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Detailed Analysis of Protein Topology of Extracellular Vesicles-Evidence of Unconventional Membrane Protein Orientation.
Sci Rep. 2016 Nov 8;6:36338. doi: 10.1038/srep36338.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources.
J Extracell Vesicles. 2016 Nov 17;5:32570. doi: 10.3402/jev.v5.32570. eCollection 2016.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources.
J Extracell Vesicles. 2016 Nov 17;5:32570. doi: 10.3402/jev.v5.32570. eCollection 2016.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic analysis of urinary extracellular vesicles from high Gleason score prostate cancer.
Sci Rep. 2017 Feb 17;7:42961. doi: 10.1038/srep42961.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic analysis of urinary extracellular vesicles from high Gleason score prostate cancer.
Sci Rep. 2017 Feb 17;7:42961. doi: 10.1038/srep42961.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic analysis of urinary extracellular vesicles from high Gleason score prostate cancer.
Sci Rep. 2017 Feb 17;7:42961. doi: 10.1038/srep42961.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Multiple extracellular vesicle types in peritoneal dialysis effluent are prominent and contain known biomarkers.
PLoS One. 2017 Jun 8;12(6):e0178601. doi: 10.1371/journal.pone.0178601. eCollection 2017.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Insulin mediated activation of PI3K/Akt signalling pathway modifies the proteomic cargo of extracellular vesicles.
Proteomics. 2017 Aug 26. doi: 10.1002/pmic.201600371.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Quantitation of putative colorectal cancer biomarker candidates in serum extracellular vesicles by targeted proteomics.
Sci Rep. 2017 Oct 6;7(1):12782. doi: 10.1038/s41598-017-13092-x.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Tetraspanin CD63 bridges autophagic and endosomal processes to regulate exosomal secretion and intracellular signaling of Epstein-Barr virus LMP1.
J Virol. 2017 Dec 6. pii: JVI.01969-17. doi: 10.1128/JVI.01969-17.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Hepatic stellate cell-derived PDGFRalpha-enriched extracellular vesicles promote liver fibrosis in mice through SHP2.
Hepatology. 2018 Jan 23. doi: 10.1002/hep.29803.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Hepatic stellate cell-derived PDGFRalpha-enriched extracellular vesicles promote liver fibrosis in mice through SHP2.
Hepatology. 2018 Jan 23. doi: 10.1002/hep.29803.
COG0491149 / 4 / 145
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)Q68D91Hepatic stellate cell-derived PDGFRalpha-enriched extracellular vesicles promote liver fibrosis in mice through SHP2.
Hepatology. 2018 Jan 23. doi: 10.1002/hep.29803.
COG0491149 / 4 / 145
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