This menu provides the list of EV proteins identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
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  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
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Protein name UniProt accession Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Isolation and identification of potential urinary microparticle biomarkers of bladder cancer.
J Proteome Res. 2008 May;7(5):2088-96. doi: 10.1021/pr700775x. Epub 2008 Mar 29.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Isolation and identification of potential urinary microparticle biomarkers of bladder cancer.
J Proteome Res. 2008 May;7(5):2088-96. doi: 10.1021/pr700775x. Epub 2008 Mar 29.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Large-scale proteomics and phosphoproteomics of urinary exosomes.
J Am Soc Nephrol. 2009 Feb;20(2):363-79. doi: 10.1681/ASN.2008040406. Epub 2008 Dec 3.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
J Proteome Res. 2009 Mar;8(3):1304-14. doi: 10.1021/pr800658c.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Proteomics analysis of bladder cancer exosomes.
Mol Cell Proteomics. 2010 Jun;9(6):1324-38. doi: 10.1074/mcp.M000063-MCP201. Epub 2010 Mar 11.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Microfiltration isolation of human urinary exosomes for characterization by MS.
Proteomics Clin Appl. 2010 Jan;4(1):84-96. doi: 10.1002/prca.200800093. Epub 2009 Nov 11.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Proteomics. 2011 Jun;11(12):2459-75. doi: 10.1002/pmic.201000443. Epub 2011 May 18.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Proteomics. 2011 Jun;11(12):2459-75. doi: 10.1002/pmic.201000443. Epub 2011 May 18.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT).
Proteomics. 2012 Jan;12(2):329-38. doi: 10.1002/pmic.201100477. Epub 2011 Dec 16.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271The protein interaction network of extracellular vesicles derived from human colorectal cancer cells.
J Proteome Res. 2012 Feb 3;11(2):1144-51. doi: 10.1021/pr200842h. Epub 2012 Jan 9.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability.
J Proteomics. 2012 Jun 27;75(12):3574-84. doi: 10.1016/j.jprot.2012.03.054. Epub 2012 Apr 10.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability.
J Proteomics. 2012 Jun 27;75(12):3574-84. doi: 10.1016/j.jprot.2012.03.054. Epub 2012 Apr 10.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability.
J Proteomics. 2012 Jun 27;75(12):3574-84. doi: 10.1016/j.jprot.2012.03.054. Epub 2012 Apr 10.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Comparative and targeted proteomic analyses of urinary microparticles from bladder cancer and hernia patients.
J Proteome Res. 2012 Dec 7;11(12):5611-29. doi: 10.1021/pr3008732. Epub 2012 Oct 31.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Comparative and targeted proteomic analyses of urinary microparticles from bladder cancer and hernia patients.
J Proteome Res. 2012 Dec 7;11(12):5611-29. doi: 10.1021/pr3008732. Epub 2012 Oct 31.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids.
Mol Cell Proteomics. 2013 Mar;12(3):587-98. doi: 10.1074/mcp.M112.021303. Epub 2012 Dec 10.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Differential protein profiling of renal cell carcinoma urinary exosomes.
Mol Biosyst. 2013 Jun;9(6):1220-33. doi: 10.1039/c3mb25582d. Epub 2013 Mar 19.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Differential protein profiling of renal cell carcinoma urinary exosomes.
Mol Biosyst. 2013 Jun;9(6):1220-33. doi: 10.1039/c3mb25582d. Epub 2013 Mar 19.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
Proteomics. 2013 May;13(10-11):1667-71. doi: 10.1002/pmic.201200561. Epub 2013 Apr 23.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions.
Proteomics. 2013 Jul;13(14):2125-34. doi: 10.1002/pmic.201200323.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Oncogenic H-ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition.
Mol Cell Proteomics. 2013 Aug;12(8):2148-59. doi: 10.1074/mcp.M112.027086. Epub 2013 May 3.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Oncogenic H-ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition.
Mol Cell Proteomics. 2013 Aug;12(8):2148-59. doi: 10.1074/mcp.M112.027086. Epub 2013 May 3.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.
J Extracell Vesicles. 2013 Dec 23;2. doi: 10.3402/jev.v2i0.22097. eCollection 2013.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.
J Extracell Vesicles. 2013 Dec 23;2. doi: 10.3402/jev.v2i0.22097. eCollection 2013.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.
Biochem Biophys Res Commun. 2014 Mar 21;445(4):694-701. doi: 10.1016/j.bbrc.2013.12.070. Epub 2014 Jan 14.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271A New Workflow for Proteomic Analysis of Urinary Exosomes and Assessment in Cystinuria Patients.
J Proteome Res. 2014 Nov 12.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271A New Workflow for Proteomic Analysis of Urinary Exosomes and Assessment in Cystinuria Patients.
J Proteome Res. 2014 Nov 12.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Intraluminal proteome and peptidome of human urinary extracellular vesicles.
Proteomics Clin Appl. 2014 Dec 4. doi: 10.1002/prca.201400085.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Exosomes released from breast cancer carcinomas stimulate cell movement.
PLoS One. 2015 Mar 23;10(3):e0117495. doi: 10.1371/journal.pone.0117495. eCollection 2015.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Exosomes as nanocarriers for systemic delivery of the Helicobacter pylori virulence factor CagA.
Sci Rep. 2016 Jan 7;6:18346. doi: 10.1038/srep18346.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Exosomes mediated pentose phosphate pathway in ovarian cancer metastasis: a proteomics analysis.
Int J Clin Exp Pathol. 2015 Dec 1;8(12):15719-28. eCollection 2015.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Exosomes in the nose induce immune cell trafficking and harbour an altered protein cargo in chronic airway inflammation.
J Transl Med. 2016 Jun 20;14(1):181. doi: 10.1186/s12967-016-0927-4.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer.
Oncotarget. 2016 Aug 8. doi: 10.18632/oncotarget.11111.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer.
Oncotarget. 2016 Aug 8. doi: 10.18632/oncotarget.11111.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Extracellular vesicles as a source for non-invasive biomarkers in bladder cancer progression.
Eur J Pharm Sci. 2016 Oct 14. pii: S0928-0987(16)30431-6. doi: 10.1016/j.ejps.2016.10.008.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Extracellular vesicles as a source for non-invasive biomarkers in bladder cancer progression.
Eur J Pharm Sci. 2016 Oct 14. pii: S0928-0987(16)30431-6. doi: 10.1016/j.ejps.2016.10.008.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Extracellular vesicles as a source for non-invasive biomarkers in bladder cancer progression.
Eur J Pharm Sci. 2016 Oct 14. pii: S0928-0987(16)30431-6. doi: 10.1016/j.ejps.2016.10.008.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Proteomic analysis of urinary extracellular vesicles from high Gleason score prostate cancer.
Sci Rep. 2017 Feb 17;7:42961. doi: 10.1038/srep42961.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Proteomic analysis of urinary extracellular vesicles from high Gleason score prostate cancer.
Sci Rep. 2017 Feb 17;7:42961. doi: 10.1038/srep42961.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Proteomic analysis of urinary extracellular vesicles from high Gleason score prostate cancer.
Sci Rep. 2017 Feb 17;7:42961. doi: 10.1038/srep42961.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Quantitative changes in the protein and miRNA cargo of plasma exosome-like vesicles after exposure to ionizing radiation.
Int J Radiat Biol. 2017 Mar 7:1-12. doi: 10.1080/09553002.2017.1294772.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Quantitative changes in the protein and miRNA cargo of plasma exosome-like vesicles after exposure to ionizing radiation.
Int J Radiat Biol. 2017 Mar 7:1-12. doi: 10.1080/09553002.2017.1294772.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Residual urinary extracellular vesicles in ultracentrifugation supernatants after hydrostatic filtration dialysis enrichment.
J Extracell Vesicles. 2016 Dec 23;6(1):1267896. doi: 10.1080/20013078.2016.1267896. eCollection 2017.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Urinary exosomes reveal protein signatures in hypertensive patients with albuminuria.
Oncotarget. 2017 May 11. doi: 10.18632/oncotarget.17787.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Feasibility of urinary extracellular vesicle proteome profiling using a robust and simple, clinically applicable isolation method.
J Extracell Vesicles. 2017 Apr 28;6(1):1313091. doi: 10.1080/20013078.2017.1313091. eCollection 2017.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Feasibility of urinary extracellular vesicle proteome profiling using a robust and simple, clinically applicable isolation method.
J Extracell Vesicles. 2017 Apr 28;6(1):1313091. doi: 10.1080/20013078.2017.1313091. eCollection 2017.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Feasibility of urinary extracellular vesicle proteome profiling using a robust and simple, clinically applicable isolation method.
J Extracell Vesicles. 2017 Apr 28;6(1):1313091. doi: 10.1080/20013078.2017.1313091. eCollection 2017.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Oncogenic transformation of lung cells results in distinct exosome protein profile similar to the cell of origin.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600432.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Oncogenic transformation of lung cells results in distinct exosome protein profile similar to the cell of origin.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600432.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Comprehensive proteomics analysis of exosomes derived from human seminal plasma.
Andrology. 2017 Sep;5(5):1007-1015. doi: 10.1111/andr.12412.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Radiation alters the cargo of exosomes released from squamous head and neck cancer cells to promote migration of recipient cells.
Sci Rep. 2017 Sep 29;7(1):12423. doi: 10.1038/s41598-017-12403-6.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Radiation alters the cargo of exosomes released from squamous head and neck cancer cells to promote migration of recipient cells.
Sci Rep. 2017 Sep 29;7(1):12423. doi: 10.1038/s41598-017-12403-6.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Quantitation of putative colorectal cancer biomarker candidates in serum extracellular vesicles by targeted proteomics.
Sci Rep. 2017 Oct 6;7(1):12782. doi: 10.1038/s41598-017-13092-x.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
ENOG410XRG0143 / 0 / 143
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)Q8N271Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
ENOG410XRG0143 / 0 / 143
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