This menu provides the list of EV proteins identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
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  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
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Protein name UniProt accession Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
Protein BRICK1 (BRK1)Q8WUW1MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Immunol Cell Biol. 2010 Nov-Dec;88(8):851-6. doi: 10.1038/icb.2010.64. Epub 2010 May 11.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT).
Proteomics. 2012 Jan;12(2):329-38. doi: 10.1002/pmic.201100477. Epub 2011 Dec 16.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Characterization of human thymic exosomes.
PLoS One. 2013 Jul 2;8(7):e67554. doi: 10.1371/journal.pone.0067554. Print 2013.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes.
J Extracell Vesicles. 2012 Apr 16;1. doi: 10.3402/jev.v1i0.18396. eCollection 2012.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.
Biochem Biophys Res Commun. 2014 Mar 21;445(4):694-701. doi: 10.1016/j.bbrc.2013.12.070. Epub 2014 Jan 14.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Quantitative proteomics of extracellular vesicles released from human monocyte-derived macrophages upon beta-glucan stimulation.
J Proteome Res. 2014 May 2;13(5):2468-77. doi: 10.1021/pr4012552. Epub 2014 Apr 16.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets.
Transfusion. 2014 Oct 21. doi: 10.1111/trf.12874.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets.
Transfusion. 2014 Oct 21. doi: 10.1111/trf.12874.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Exosome enrichment of human serum using multiple cycles of centrifugation.
Electrophoresis. 2015 May 23. doi: 10.1002/elps.201500131.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Microparticles released from Mycobacterium tuberculosis-infected human macrophages contain increased levels of the type I interferon inducible proteins including ISG15.
Proteomics. 2015 Jun 2. doi: 10.1002/pmic.201400610.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Microparticles released from Mycobacterium tuberculosis-infected human macrophages contain increased levels of the type I interferon inducible proteins including ISG15.
Proteomics. 2015 Jun 2. doi: 10.1002/pmic.201400610.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts.
Blood. 2015 Jun 22. pii: blood-2014-12-618025.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Exosomes mediated pentose phosphate pathway in ovarian cancer metastasis: a proteomics analysis.
Int J Clin Exp Pathol. 2015 Dec 1;8(12):15719-28. eCollection 2015.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Exosomes mediated pentose phosphate pathway in ovarian cancer metastasis: a proteomics analysis.
Int J Clin Exp Pathol. 2015 Dec 1;8(12):15719-28. eCollection 2015.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Effective isolation of exosomes with polyethylene glycol from cell culture supernatant for in-depth proteome profiling.
Analyst. 2016 May 27.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Exosomes in the nose induce immune cell trafficking and harbour an altered protein cargo in chronic airway inflammation.
J Transl Med. 2016 Jun 20;14(1):181. doi: 10.1186/s12967-016-0927-4.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic Analysis of Exosomes and Exosome-Free Conditioned Media Derived from Human Osteosarcoma Cell Lines Reveal Differential Secretion of Proteins Related to Biological Functions and Tumor Progression.
J Cell Biochem. 2016 Jun 30. doi: 10.1002/jcb.25642.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic Analysis of Exosomes and Exosome-Free Conditioned Media Derived from Human Osteosarcoma Cell Lines Reveal Differential Secretion of Proteins Related to Biological Functions and Tumor Progression.
J Cell Biochem. 2016 Jun 30. doi: 10.1002/jcb.25642.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Efficient production and enhanced tumor delivery of engineered extracellular vesicles.
Biomaterials. 2016 Jul 6;105:195-205. doi: 10.1016/j.biomaterials.2016.07.003.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Identification and Characterization of 293T Cell-Derived Exosomes by Profiling the Protein, mRNA and MicroRNA Components.
PLoS One. 2016 Sep 20;11(9):e0163043. doi: 10.1371/journal.pone.0163043. eCollection 2016.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic and bioinformatic characterization of extracellular vesicles released from human macrophages upon influenza A virus infection.
J Proteome Res. 2016 Oct 11.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Candida albicans Modifies the Protein Composition and Size Distribution of THP1 macrophages-derived Extracellular Vesicles.
J Proteome Res. 2016 Oct 14.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Candida albicans Modifies the Protein Composition and Size Distribution of THP1 macrophages-derived Extracellular Vesicles.
J Proteome Res. 2016 Oct 14.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Detailed Analysis of Protein Topology of Extracellular Vesicles-Evidence of Unconventional Membrane Protein Orientation.
Sci Rep. 2016 Nov 8;6:36338. doi: 10.1038/srep36338.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic analysis of urinary extracellular vesicles from high Gleason score prostate cancer.
Sci Rep. 2017 Feb 17;7:42961. doi: 10.1038/srep42961.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic analysis of urinary extracellular vesicles from high Gleason score prostate cancer.
Sci Rep. 2017 Feb 17;7:42961. doi: 10.1038/srep42961.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic analysis of urinary extracellular vesicles from high Gleason score prostate cancer.
Sci Rep. 2017 Feb 17;7:42961. doi: 10.1038/srep42961.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Multiple extracellular vesicle types in peritoneal dialysis effluent are prominent and contain known biomarkers.
PLoS One. 2017 Jun 8;12(6):e0178601. doi: 10.1371/journal.pone.0178601. eCollection 2017.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Multiple extracellular vesicle types in peritoneal dialysis effluent are prominent and contain known biomarkers.
PLoS One. 2017 Jun 8;12(6):e0178601. doi: 10.1371/journal.pone.0178601. eCollection 2017.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Quantitation of putative colorectal cancer biomarker candidates in serum extracellular vesicles by targeted proteomics.
Sci Rep. 2017 Oct 6;7(1):12782. doi: 10.1038/s41598-017-13092-x.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Quantitation of putative colorectal cancer biomarker candidates in serum extracellular vesicles by targeted proteomics.
Sci Rep. 2017 Oct 6;7(1):12782. doi: 10.1038/s41598-017-13092-x.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients.
Ann Oncol. 2017 Sep 25. doi: 10.1093/annonc/mdx542.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Tetraspanin CD63 bridges autophagic and endosomal processes to regulate exosomal secretion and intracellular signaling of Epstein-Barr virus LMP1.
J Virol. 2017 Dec 6. pii: JVI.01969-17. doi: 10.1128/JVI.01969-17.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Hepatic stellate cell-derived PDGFRalpha-enriched extracellular vesicles promote liver fibrosis in mice through SHP2.
Hepatology. 2018 Jan 23. doi: 10.1002/hep.29803.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Hepatic stellate cell-derived PDGFRalpha-enriched extracellular vesicles promote liver fibrosis in mice through SHP2.
Hepatology. 2018 Jan 23. doi: 10.1002/hep.29803.
ENOG4111UHX80 / 0 / 80
Protein BRICK1 (BRK1)Q8WUW1Hepatic stellate cell-derived PDGFRalpha-enriched extracellular vesicles promote liver fibrosis in mice through SHP2.
Hepatology. 2018 Jan 23. doi: 10.1002/hep.29803.
ENOG4111UHX80 / 0 / 80
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