This menu provides the list of EV proteins identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
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  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
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Protein name UniProt accession Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
Ras-related protein Rab-5AQ9CQD1Cells release prions in association with exosomes.
Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9683-8. Epub 2004 Jun 21.
ENOG410YCCP394 / 0 / 394
Ras-related protein Rab-5AQ9CQD1Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Nat Cell Biol. 2007 Jun;9(6):654-9. Epub 2007 May 7.
ENOG410YCCP394 / 0 / 394
Ras-related protein Rab-5AQ9CQD1Proteomic analysis of C2C12 myoblast and myotube exosome-like vesicles: a new paradigm for myoblast-myotube cross talk?
PLoS One. 2014 Jan 2;9(1):e84153. doi: 10.1371/journal.pone.0084153. eCollection 2014.
ENOG410YCCP394 / 0 / 394
Ras-related protein Rab-5AQ9CQD1Proteomic analysis of C2C12 myoblast and myotube exosome-like vesicles: a new paradigm for myoblast-myotube cross talk?
PLoS One. 2014 Jan 2;9(1):e84153. doi: 10.1371/journal.pone.0084153. eCollection 2014.
ENOG410YCCP394 / 0 / 394
Ras-related protein Rab-5AQ9CQD1Extracellular Vesicles from Neural Stem Cells Transfer IFN-gamma via Ifngr1 to Activate Stat1 Signaling in Target Cells.
Mol Cell. 2014 Sep 16. pii: S1097-2765(14)00675-3. doi: 10.1016/j.molcel.2014.08.020.
ENOG410YCCP394 / 0 / 394
Ras-related protein Rab-5AQ9CQD1Extracellular Vesicles from Neural Stem Cells Transfer IFN-gamma via Ifngr1 to Activate Stat1 Signaling in Target Cells.
Mol Cell. 2014 Sep 16. pii: S1097-2765(14)00675-3. doi: 10.1016/j.molcel.2014.08.020.
ENOG410YCCP394 / 0 / 394
Ras-related protein Rab-5AQ9CQD1Membrane microvesicles as mediators for melanoma-fibroblasts communication: Roles of the VCAM-1/VLA-4 axis and the ERK1/2 signal pathway.
Cancer Lett. 2015 Feb 4. pii: S0304-3835(15)00066-X. doi: 10.1016/j.canlet.2015.01.032.
ENOG410YCCP394 / 0 / 394
Ras-related protein Rab-5AQ9CQD1Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver.
Nat Cell Biol. 2015 May 18. doi: 10.1038/ncb3169.
ENOG410YCCP394 / 0 / 394
Ras-related protein Rab-5AQ9CQD1A comprehensive proteomics analysis reveals a secretory path- and status-dependent signature of exosomes released from tumor associated macrophages.
J Proteome Res. 2015 Aug 27.
ENOG410YCCP394 / 0 / 394
Ras-related protein Rab-5AQ9CQD1A comprehensive proteomics analysis reveals a secretory path- and status-dependent signature of exosomes released from tumor associated macrophages.
J Proteome Res. 2015 Aug 27.
ENOG410YCCP394 / 0 / 394
Ras-related protein Rab-5AQ9CQD1Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.
ENOG410YCCP394 / 0 / 394
Ras-related protein Rab-5AQ9CQD1Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.
ENOG410YCCP394 / 0 / 394
Ras-related protein Rab-5AQ9CQD1Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.
ENOG410YCCP394 / 0 / 394
Ras-related protein Rab-5AQ9CQD1Enrichment of extracellular vesicles from tissues of the central nervous system by PROSPR.
Mol Neurodegener. 2016 May 23;11(1):41. doi: 10.1186/s13024-016-0108-1.
ENOG410YCCP394 / 0 / 394
Ras-related protein Rab-5AQ9CQD1Microvesicles provide a mechanism for intercellular communication by embryonic stem cells during embryo implantation.
Nat Commun. 2016 Jun 15;7:11958. doi: 10.1038/ncomms11958.
ENOG410YCCP394 / 0 / 394
Ras-related protein Rab-5AQ9CQD1Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer.
Oncotarget. 2016 Aug 23. doi: 10.18632/oncotarget.11535.
ENOG410YCCP394 / 0 / 394
Ras-related protein Rab-5AQ9CQD1Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer.
Oncotarget. 2016 Aug 23. doi: 10.18632/oncotarget.11535.
ENOG410YCCP394 / 0 / 394
Ras-related protein Rab-5AQ9CQD1Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer.
Oncotarget. 2016 Aug 23. doi: 10.18632/oncotarget.11535.
ENOG410YCCP394 / 0 / 394
Ras-related protein Rab-5AQ9CQD1Thymic exosomes promote the final maturation of thymocytes.
Sci Rep. 2016 Nov 8;6:36479. doi: 10.1038/srep36479.
ENOG410YCCP394 / 0 / 394
Ras-related protein Rab-5AQ9CQD1Secreted Glioblastoma Nanovesicles Contain Intracellular Signaling Proteins and Active Ras Incorporated in a Farnesylation-dependent Manner.
J Biol Chem. 2016 Dec 1. pii: jbc.M116.747618.
ENOG410YCCP394 / 0 / 394
Ras-related protein Rab-5AQ9CQD1Characterisation of adipocyte-derived extracellular vesicle subtypes identifies distinct protein and lipid signatures for large and small extracellular vesicles.
J Extracell Vesicles. 2017 Apr 10;6(1):1305677. doi: 10.1080/20013078.2017.1305677. eCollection 2017.
ENOG410YCCP394 / 0 / 394
Ras-related protein Rab-5AQ9CQD1Hypoxia-induced changes in the fibroblast secretome, exosome, and whole-cell proteome using cultured, cardiac-derived cells isolated from neonatal mice.
J Proteome Res. 2017 Jun 22. doi: 10.1021/acs.jproteome.7b00144.
ENOG410YCCP394 / 0 / 394
Ras-related protein Rab-5AQ9CQD1Hypoxia-induced changes in the fibroblast secretome, exosome, and whole-cell proteome using cultured, cardiac-derived cells isolated from neonatal mice.
J Proteome Res. 2017 Jun 22. doi: 10.1021/acs.jproteome.7b00144.
ENOG410YCCP394 / 0 / 394
Ras-related protein Rab-5AQ9CQD1Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.
ENOG410YCCP394 / 0 / 394
Ras-related protein Rab-5AQ9CQD1Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.
ENOG410YCCP394 / 0 / 394
Ras-related protein Rab-5AQ9CQD1Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.
ENOG410YCCP394 / 0 / 394
Ras-related protein Rab-5AQ9CQD1Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.
ENOG410YCCP394 / 0 / 394
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