This menu provides the list of EV proteins identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
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  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
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Protein name UniProt accession Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Q9DAS9Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?
Proteomics Clin Appl. 2007 Nov;1(11):1446-61. doi: 10.1002/prca.200700522. Epub 2007 Oct 16.		ENOG41122JF271 / 0 / 271
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Q9DAS9Extracellular Vesicles from Neural Stem Cells Transfer IFN-gamma via Ifngr1 to Activate Stat1 Signaling in Target Cells.
Mol Cell. 2014 Sep 16. pii: S1097-2765(14)00675-3. doi: 10.1016/j.molcel.2014.08.020.		ENOG41122JF271 / 0 / 271
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Q9DAS9Extracellular Vesicles from Neural Stem Cells Transfer IFN-gamma via Ifngr1 to Activate Stat1 Signaling in Target Cells.
Mol Cell. 2014 Sep 16. pii: S1097-2765(14)00675-3. doi: 10.1016/j.molcel.2014.08.020.		ENOG41122JF271 / 0 / 271
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Q9DAS9Membrane microvesicles as mediators for melanoma-fibroblasts communication: Roles of the VCAM-1/VLA-4 axis and the ERK1/2 signal pathway.
Cancer Lett. 2015 Feb 4. pii: S0304-3835(15)00066-X. doi: 10.1016/j.canlet.2015.01.032.		ENOG41122JF271 / 0 / 271
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Q9DAS9Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.		ENOG41122JF271 / 0 / 271
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Q9DAS9Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.		ENOG41122JF271 / 0 / 271
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Q9DAS9Cells release subpopulations of exosomes with distinct molecular and biological properties.
Sci Rep. 2016 Mar 2;6:22519. doi: 10.1038/srep22519.		ENOG41122JF271 / 0 / 271
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Q9DAS9Adipocyte exosomes promote melanoma aggressiveness through fatty acid oxidation: a novel mechanism linking obesity and cancer.
Cancer Res. 2016 May 23. pii: canres.0651.2016.		ENOG41122JF271 / 0 / 271
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Q9DAS9Procoagulant and immunogenic properties of melanoma exosomes, microvesicles and apoptotic vesicles.
Oncotarget. 2016 Jul 22. doi: 10.18632/oncotarget.10783.		ENOG41122JF271 / 0 / 271
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Q9DAS9Procoagulant and immunogenic properties of melanoma exosomes, microvesicles and apoptotic vesicles.
Oncotarget. 2016 Jul 22. doi: 10.18632/oncotarget.10783.		ENOG41122JF271 / 0 / 271
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Q9DAS9Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer.
Oncotarget. 2016 Aug 23. doi: 10.18632/oncotarget.11535.		ENOG41122JF271 / 0 / 271
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Q9DAS9Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer.
Oncotarget. 2016 Aug 23. doi: 10.18632/oncotarget.11535.		ENOG41122JF271 / 0 / 271
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Q9DAS9Macrophage Foam Cell-Derived Extracellular Vesicles Promote Vascular Smooth Muscle Cell Migration and Adhesion.
J Am Heart Assoc. 2016 Oct 17;5(10). pii: e004099.		ENOG41122JF271 / 0 / 271
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Q9DAS9Thymic exosomes promote the final maturation of thymocytes.
Sci Rep. 2016 Nov 8;6:36479. doi: 10.1038/srep36479.		ENOG41122JF271 / 0 / 271
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Q9DAS9Secreted Glioblastoma Nanovesicles Contain Intracellular Signaling Proteins and Active Ras Incorporated in a Farnesylation-dependent Manner.
J Biol Chem. 2016 Dec 1. pii: jbc.M116.747618.		ENOG41122JF271 / 0 / 271
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Q9DAS9Astrocyte-shed extracellular vesicles regulate the peripheral leukocyte response to inflammatory brain lesions.
Sci Signal. 2017 Apr 4;10(473). pii: eaai7696. doi: 10.1126/scisignal.aai7696.		ENOG41122JF271 / 0 / 271
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Q9DAS9Hypoxia-induced changes in the fibroblast secretome, exosome, and whole-cell proteome using cultured, cardiac-derived cells isolated from neonatal mice.
J Proteome Res. 2017 Jun 22. doi: 10.1021/acs.jproteome.7b00144.		ENOG41122JF271 / 0 / 271
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Q9DAS9Hypoxia-induced changes in the fibroblast secretome, exosome, and whole-cell proteome using cultured, cardiac-derived cells isolated from neonatal mice.
J Proteome Res. 2017 Jun 22. doi: 10.1021/acs.jproteome.7b00144.		ENOG41122JF271 / 0 / 271
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Q9DAS9Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses.
J Extracell Vesicles. 2017 Aug 13;6(1):1359478. doi: 10.1080/20013078.2017.1359478. eCollection 2017.		ENOG41122JF271 / 0 / 271
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Q9DAS9Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses.
J Extracell Vesicles. 2017 Aug 13;6(1):1359478. doi: 10.1080/20013078.2017.1359478. eCollection 2017.		ENOG41122JF271 / 0 / 271
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Q9DAS9Effects of storage temperature on airway exosome integrity for diagnostic and functional analyses.
J Extracell Vesicles. 2017 Aug 13;6(1):1359478. doi: 10.1080/20013078.2017.1359478. eCollection 2017.		ENOG41122JF271 / 0 / 271
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Q9DAS9Increased Release of Apolipoprotein E in Extracellular Vesicles Following Amyloid-beta Protofibril Exposure of Neuroglial Co-Cultures.
J Alzheimers Dis. 2017 Aug 17. doi: 10.3233/JAD-170278.		ENOG41122JF271 / 0 / 271
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Q9DAS9Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.		ENOG41122JF271 / 0 / 271
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Q9DAS9Proteomic profiling of exosomes secreted by breast cancer cells with varying metastatic potential.
Proteomics. 2017 Nov 8. doi: 10.1002/pmic.201600370.		ENOG41122JF271 / 0 / 271
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