This menu provides the list of EV proteins identified by high-throughput analyses.

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Superdomain: All Prokaryote Eukaryote
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  - "Sample type" indicates the source from which EVs originated (e.g. B cell, serum).
  - "Sample status" indicates the condition of the source from which EVs originated (e.g. Normal, miR-146a-treated, Patients of hernia).
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Protein name UniProt accession Publication Orthologous group Identification count
All / Prokaryote / Eukaryote
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3The protein interaction network of extracellular vesicles derived from human colorectal cancer cells.
J Proteome Res. 2012 Feb 3;11(2):1144-51. doi: 10.1021/pr200842h. Epub 2012 Jan 9.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Characterization and proteomic analysis of ovarian cancer-derived exosomes.
J Proteomics. 2013 Jan 16;80C:171-182. doi: 10.1016/j.jprot.2012.12.029.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients.
J Extracell Vesicles. 2013 Dec 23;2. doi: 10.3402/jev.v2i0.22097. eCollection 2013.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential expression of EMT factors.
Proteomics. 2014 Mar;14(6):699-712. doi: 10.1002/pmic.201300452. Epub 2014 Feb 16.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential expression of EMT factors.
Proteomics. 2014 Mar;14(6):699-712. doi: 10.1002/pmic.201300452. Epub 2014 Feb 16.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential expression of EMT factors.
Proteomics. 2014 Mar;14(6):699-712. doi: 10.1002/pmic.201300452. Epub 2014 Feb 16.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.
Biochem Biophys Res Commun. 2014 Mar 21;445(4):694-701. doi: 10.1016/j.bbrc.2013.12.070. Epub 2014 Jan 14.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic analysis of cerebrospinal fluid extracellular vesicles: a comprehensive dataset.
J Proteomics. 2014 Jun 25;106:191-204. doi: 10.1016/j.jprot.2014.04.028. Epub 2014 Apr 24.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes.
Oncotarget. 2015 Apr 12.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts.
Blood. 2015 Jun 22. pii: blood-2014-12-618025.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts.
Blood. 2015 Jun 22. pii: blood-2014-12-618025.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts.
Blood. 2015 Jun 22. pii: blood-2014-12-618025.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Enrichment of extracellular vesicles from tissues of the central nervous system by PROSPR.
Mol Neurodegener. 2016 May 23;11(1):41. doi: 10.1186/s13024-016-0108-1.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Effective isolation of exosomes with polyethylene glycol from cell culture supernatant for in-depth proteome profiling.
Analyst. 2016 May 27.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic Analysis of Exosomes and Exosome-Free Conditioned Media Derived from Human Osteosarcoma Cell Lines Reveal Differential Secretion of Proteins Related to Biological Functions and Tumor Progression.
J Cell Biochem. 2016 Jun 30. doi: 10.1002/jcb.25642.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic Analysis of Exosomes and Exosome-Free Conditioned Media Derived from Human Osteosarcoma Cell Lines Reveal Differential Secretion of Proteins Related to Biological Functions and Tumor Progression.
J Cell Biochem. 2016 Jun 30. doi: 10.1002/jcb.25642.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Secreted primary human malignant mesothelioma exosome signature reflects oncogenic cargo.
Sci Rep. 2016 Sep 8;6:32643. doi: 10.1038/srep32643.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Secreted primary human malignant mesothelioma exosome signature reflects oncogenic cargo.
Sci Rep. 2016 Sep 8;6:32643. doi: 10.1038/srep32643.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Identification and Characterization of 293T Cell-Derived Exosomes by Profiling the Protein, mRNA and MicroRNA Components.
PLoS One. 2016 Sep 20;11(9):e0163043. doi: 10.1371/journal.pone.0163043. eCollection 2016.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources.
J Extracell Vesicles. 2016 Nov 17;5:32570. doi: 10.3402/jev.v5.32570. eCollection 2016.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources.
J Extracell Vesicles. 2016 Nov 17;5:32570. doi: 10.3402/jev.v5.32570. eCollection 2016.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources.
J Extracell Vesicles. 2016 Nov 17;5:32570. doi: 10.3402/jev.v5.32570. eCollection 2016.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
Oncotarget. 2016 Nov 24. doi: 10.18632/oncotarget.13569.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Motile hepatocellular carcinoma cells preferentially secret sugar metabolism regulatory proteins via exosomes.
Proteomics. 2017 Jun 7. doi: 10.1002/pmic.201700103.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Motile hepatocellular carcinoma cells preferentially secret sugar metabolism regulatory proteins via exosomes.
Proteomics. 2017 Jun 7. doi: 10.1002/pmic.201700103.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Motile hepatocellular carcinoma cells preferentially secret sugar metabolism regulatory proteins via exosomes.
Proteomics. 2017 Jun 7. doi: 10.1002/pmic.201700103.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Phytoagent Deoxyelephantopin and Its Derivative Inhibit Triple Negative Breast Cancer Cell Activity through ROS-Mediated Exosomal Activity and Protein Functions.
Front Pharmacol. 2017 Jun 29;8:398. doi: 10.3389/fphar.2017.00398. eCollection 2017.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Phytoagent Deoxyelephantopin and Its Derivative Inhibit Triple Negative Breast Cancer Cell Activity through ROS-Mediated Exosomal Activity and Protein Functions.
Front Pharmacol. 2017 Jun 29;8:398. doi: 10.3389/fphar.2017.00398. eCollection 2017.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Phytoagent Deoxyelephantopin and Its Derivative Inhibit Triple Negative Breast Cancer Cell Activity through ROS-Mediated Exosomal Activity and Protein Functions.
Front Pharmacol. 2017 Jun 29;8:398. doi: 10.3389/fphar.2017.00398. eCollection 2017.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Proteomic analysis of neuroblastoma-derived exosomes: new insights into a metastatic signature.
Proteomics. 2017 Jul 19. doi: 10.1002/pmic.201600430.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA.
Sci Rep. 2017 Aug 15;7(1):8202. doi: 10.1038/s41598-017-08392-1.
COG1498124 / 0 / 124
Nucleolar protein 58 (Nucleolar protein 5)Q9Y2X3Quantitation of putative colorectal cancer biomarker candidates in serum extracellular vesicles by targeted proteomics.
Sci Rep. 2017 Oct 6;7(1):12782. doi: 10.1038/s41598-017-13092-x.
COG1498124 / 0 / 124
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