EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.


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Protein name Gene symbol UniProt accession Identification number
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)GNB1P6287318
Guanine nucleotide-binding protein subunit alpha-11 (G alpha-11) (G-protein subunit alpha-11) (Guanine nucleotide-binding protein G(y) subunit alpha)GNA11 GA11P2999218
Heterogeneous nuclear ribonucleoprotein A1-like 2 (hnRNP A1-like 2) (hnRNP core protein A1-like 2)HNRNPA1L2 HNRNPA1LQ32P5118
Heterogeneous nuclear ribonucleoprotein H3 (hnRNP H3) (Heterogeneous nuclear ribonucleoprotein 2H9) (hnRNP 2H9)HNRNPH3 HNRPH3P3194218
Hsc70-interacting protein (Hip) (Aging-associated protein 2) (Progesterone receptor-associated p48 protein) (Protein FAM10A1) (Putative tumor suppressor ST13) (Renal carcinoma antigen NY-REN-33) (Suppression of tumorigenicity 13 protein)ST13 AAG2 FAM10A1 HIP SNC6P5050218
Inorganic pyrophosphatase 2, mitochondrial (EC (Pyrophosphatase SID6-306) (Pyrophosphate phospho-hydrolase 2) (PPase 2)PPA2 HSPC124Q9H2U218
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (EC (Isocitric dehydrogenase subunit beta) (NAD(+)-specific ICDH subunit beta)IDH3BO4383718
Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (Microtubule-associated protein 2 kinase) (p44-ERK1)MAPK3 ERK1 PRKM3P2736118
Myosin light polypeptide 6 (17 kDa myosin light chain) (LC17) (Myosin light chain 3) (MLC-3) (Myosin light chain alkali 3) (Myosin light chain A3) (Smooth muscle and nonmuscle myosin light chain alkali 6)MYL6P6066018
Non-histone chromosomal protein HMG-14 (High mobility group nucleosome-binding domain-containing protein 1)HMGN1 HMG14P0511418
Phospholipid hydroperoxide glutathione peroxidase, mitochondrial (PHGPx) (EC (Glutathione peroxidase 4) (GPx-4) (GSHPx-4)GPX4P3696918
Poly(A) polymerase alpha (PAP-alpha) (EC (Polynucleotide adenylyltransferase alpha)PAPOLA PAPP5100318
Protein SCAF11 (CTD-associated SR protein 11) (Renal carcinoma antigen NY-REN-40) (SC35-interacting protein 1) (SR-related and CTD-associated factor 11) (SRSF2-interacting protein) (Serine/arginine-rich splicing factor 2-interacting protein) (Splicing factor, arginine/serine-rich 2-interacting protein) (Splicing regulatory protein 129) (SRrp129)SCAF11 CASP11 SFRS2IP SIP1 SRSF2IPQ9959018
Protein transport protein Sec31A (ABP125) (ABP130) (SEC31-like protein 1) (SEC31-related protein A) (Web1-like protein)SEC31A KIAA0905 SEC31L1 HSPC275 HSPC334O9497918
Putative ATP-dependent RNA helicase DHX30 (EC (DEAH box protein 30)DHX30 DDX30 KIAA0890Q7L2E318
S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (Organ of Corti protein 2) (OCP-2) (Organ of Corti protein II) (OCP-II) (RNA polymerase II elongation factor-like protein) (SIII) (Transcription elongation factor B) (p19A) (p19skp1)SKP1 EMC19 OCP2 SKP1A TCEB1LP6320818
Septin-2 (Neural precursor cell expressed developmentally down-regulated protein 5) (NEDD-5)SEPT2 DIFF6 KIAA0158 NEDD5Q1501918
SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)SH3KBP1 CIN85Q96B9718
Splicing factor 3B subunit 1 (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155)SF3B1 SAP155O7553318
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (HIV-1 Nef-interacting protein)CCT7 CCTH NIP7-1Q9983218
Transcription factor E2-alpha (Class B basic helix-loop-helix protein 21) (bHLHb21) (Immunoglobulin enhancer-binding factor E12/E47) (Immunoglobulin transcription factor 1) (Kappa-E2-binding factor) (Transcription factor 3) (TCF-3) (Transcription factor ITF-1)TCF3 BHLHB21 E2A ITF1P1592318
Tubulin polyglutamylase complex subunit 2 (PGs2)TPGS2 C18orf10 HMFN0601 L17Q68CL518
UPF0450 protein C17orf58C17orf58Q2M2W718
39S ribosomal protein L11, mitochondrial (L11mt) (MRP-L11)MRPL11 CGI-113Q9Y3B717
40S ribosomal protein S13RPS13P6227717
40S ribosomal protein S14RPS14 PRO2640P6226317
6.8 kDa mitochondrial proteolipidMP68 C14orf2 PRO1574P5637817
60S ribosomal protein L11 (CLL-associated antigen KW-12)RPL11P6291317
Actin-related protein 2 (Actin-like protein 2)ACTR2 ARP2P6116017
Actin-related protein 2/3 complex subunit 5 (Arp2/3 complex 16 kDa subunit) (p16-ARC)ARPC5 ARC16O1551117
Allograft inflammatory factor 1 (AIF-1) (Ionized calcium-binding adapter molecule 1) (Protein G1)AIF1 G1 IBA1P5500817
Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein)ANAPC11 HSPC214Q9NYG517
AP-2 complex subunit mu (AP-2 mu chain) (Adapter-related protein complex 2 subunit mu) (Adaptin-mu2) (Adaptor protein complex AP-2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Plasma membrane adaptor AP-2 50 kDa protein)AP2M1 CLAPM1 KIAA0109Q96CW117
ATP synthase subunit alpha, mitochondrialATP5A1 ATP5A ATP5AL2 ATPMP2570517
Barrier-to-autointegration factor (Breakpoint cluster region protein 1) [Cleaved into: Barrier-to-autointegration factor, N-terminally processed]BANF1 BAF BCRG1O7553117
Bcl-2-associated transcription factor 1 (Btf)BCLAF1 BTF KIAA0164Q9NYF817
Calpain small subunit 1 (CSS1) (Calcium-activated neutral proteinase small subunit) (CANP small subunit) (Calcium-dependent protease small subunit) (CDPS) (Calcium-dependent protease small subunit 1) (Calpain regulatory subunit)CAPNS1 CAPN4 CAPNSP0463217
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (EC (Nuclear LIM interactor-interacting factor 3) (NLI-IF) (NLI-interacting factor 3) (Small C-terminal domain phosphatase 1) (SCP1) (Small CTD phosphatase 1)CTDSP1 NIF3 NLIIF SCP1Q9GZU717
Clathrin light chain B (Lcb)CLTBP0949717
Differentially expressed in FDCP 8 homolog (DEF-8)DEF8Q6ZN5417
DNA replication licensing factor MCM7 (EC (CDC47 homolog) (P1.1-MCM3)MCM7 CDC47 MCM2P3399317
DNA-(apurinic or apyrimidinic site) lyase (EC 3.1.-.-) (EC (APEX nuclease) (APEN) (Apurinic-apyrimidinic endonuclease 1) (AP endonuclease 1) (APE-1) (REF-1) (Redox factor-1) [Cleaved into: DNA-(apurinic or apyrimidinic site) lyase, mitochondrial]APEX1 APE APE1 APEX APX HAP1 REF1P2769517
Endothelial differentiation-related factor 1 (EDF-1) (Multiprotein-bridging factor 1) (MBF1)EDF1O6086917
ES1 protein homolog, mitochondrial (Protein GT335) (Protein KNP-I)C21orf33 HES1 KNPIP3004217
Eukaryotic translation initiation factor 3 subunit B (eIF3b) (Eukaryotic translation initiation factor 3 subunit 9) (Prt1 homolog) (hPrt1) (eIF-3-eta) (eIF3 p110) (eIF3 p116)EIF3B EIF3S9P5588417
Ferritin light chain (Ferritin L subunit)FTLP0279217
Guanidinoacetate N-methyltransferase (EC
Heterogeneous nuclear ribonucleoprotein M (hnRNP M)HNRNPM HNRPM NAGR1P5227217
Histone H3.2 (Histone H3/m) (Histone H3/o)HIST2H3A; HIST2H3C H3F2 H3FM; HIST2H3DQ71DI317
Keratin, type I cytoskeletal 18 (Cell proliferation-inducing gene 46 protein) (Cytokeratin-18) (CK-18) (Keratin-18) (K18)KRT18 CYK18 PIG46P0578317
LIM and senescent cell antigen-like-containing domain protein 1 (Particularly interesting new Cys-His protein 1) (PINCH-1) (Renal carcinoma antigen NY-REN-48)LIMS1 PINCH PINCH1P4805917
Microtubule-associated protein 4 (MAP-4)MAP4P2781617
Mitogen-activated protein kinase kinase kinase kinase 4 (EC (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)MAP4K4 HGK KIAA0687 NIKO9581917
Muscleblind-like protein 1 (Triplet-expansion RNA-binding protein)MBNL1 EXP KIAA0428 MBNLQ9NR5617
NHP2-like protein 1 (High mobility group-like nuclear protein 2 homolog 1) (OTK27) (SNU13 homolog) (hSNU13) (U4/U6.U5 tri-snRNP 15.5 kDa protein) [Cleaved into: NHP2-like protein 1, N-terminally processed]NHP2L1P5576917
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)NPM1 NPMP0674817
Pre-mRNA-splicing regulator WTAP (Female-lethal(2)D homolog) (hFL(2)D) (WT1-associated protein) (Wilms tumor 1-associating protein)WTAP KIAA0105Q1500717
Probable ATP-dependent RNA helicase DDX17 (EC (DEAD box protein 17) (DEAD box protein p72) (RNA-dependent helicase p72)DDX17Q9284117
Protein PRRC2C (BAT2 domain-containing protein 1) (HBV X-transactivated gene 2 protein) (HBV XAg-transactivated protein 2) (HLA-B-associated transcript 2-like 2) (Proline-rich and coiled-coil-containing protein 2C)PRRC2C BAT2D1 BAT2L2 KIAA1096 XTP2Q9Y52017
Protein SON (Bax antagonist selected in saccharomyces 1) (BASS1) (Negative regulatory element-binding protein) (NRE-binding protein) (Protein DBP-5) (SON3)SON C21orf50 DBP5 KIAA1019 NREBP HSPC310 HSPC312P1858317
Serine/threonine-protein kinase 24 (EC (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)]STK24 MST3 STK3Q9Y6E017
Speedy protein E3SPDYE3A6NKU917
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (Integral membrane protein CII-3) (QPs-1) (QPs1) (Succinate dehydrogenase complex subunit C) (Succinate-ubiquinone oxidoreductase cytochrome B large subunit) (CYBL)SDHC CYB560 SDH3Q9964317
Superoxide dismutase [Mn], mitochondrial (EC
Transcription elongation factor B polypeptide 1 (Elongin 15 kDa subunit) (Elongin-C) (EloC) (RNA polymerase II transcription factor SIII subunit C) (SIII p15)TCEB1Q1536917
Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta)EIF2B4 EIF2BDQ9UI1017
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)TPM3P0675317
Tubulin gamma-1 chain (Gamma-1-tubulin) (Gamma-tubulin complex component 1) (GCP-1)TUBG1 TUBGP2325817
Tyrosine-protein kinase Fyn (EC (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)FYNP0624117
Uncharacterized protein C6orf106C6orf106Q9H6K117
WD repeat-containing protein 1 (Actin-interacting protein 1) (AIP1) (NORI-1)WDR1O7508317
Y-box-binding protein 3 (Cold shock domain-containing protein A) (DNA-binding protein A) (Single-strand DNA-binding protein NF-GMB)YBX3 CSDA DBPAP1698917
60S ribosomal protein L10a (CSA-19) (Neural precursor cell expressed developmentally down-regulated protein 6) (NEDD-6)RPL10A NEDD6P6290616
60S ribosomal protein L27RPL27P6135316
60S ribosomal protein L27aRPL27AP4677616
60S ribosomal protein L37aRPL37AP6151316
ADP-ribosylation factor 3ARF3P6120416
AH receptor-interacting protein (AIP) (Aryl-hydrocarbon receptor-interacting protein) (HBV X-associated protein 2) (XAP-2) (Immunophilin homolog ARA9)AIP XAP2O0017016
Alpha-endosulfine (ARPP-19e)ENSAO4376816
ATP synthase subunit d, mitochondrial (ATPase subunit d)ATP5H My032O7594716
Casein kinase I isoform alpha (CKI-alpha) (EC (CK1)CSNK1A1P4872916
Cathepsin B (EC (APP secretase) (APPS) (Cathepsin B1) [Cleaved into: Cathepsin B light chain; Cathepsin B heavy chain]CTSB CPSBP0785816
cDNA, FLJ93604, highly similar to Homo sapiens major histocompatibility complex, class I, A (HLA-A),mRNA0B2R7U316
Chromobox protein homolog 6CBX6O9550316
Cocaine esterase (EC (Carboxylesterase 2) (CE-2) (hCE-2) (EC (Methylumbelliferyl-acetate deacetylase 2) (EC ICEO0074816
Coiled-coil domain-containing protein 34 (Renal carcinoma antigen NY-REN-41)CCDC34 RAMA3 L15Q96HJ316
Constitutive coactivator of PPAR-gamma-like protein 1 (Oxidative stress-associated Src activator) (Protein FAM120A)FAM120A C9orf10 KIAA0183 OSSAQ9NZB216
Dexamethasone-induced protein (Protein MYLE)DEXI MYLEO9542416
Disks large-associated protein 4 (DAP-4) (PSD-95/SAP90-binding protein 4) (SAP90/PSD-95-associated protein 4) (SAPAP-4)DLGAP4 DAP4 KIAA0964 SAPAP4Q9Y2H016
Double-stranded RNA-specific adenosine deaminase (DRADA) (EC (136 kDa double-stranded RNA-binding protein) (p136) (Interferon-inducible protein 4) (IFI-4) (K88DSRBP)ADAR ADAR1 DSRAD G1P1 IFI4P5526516
Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase 3) (MAPKK 3) (EC (MAPK/ERK kinase 3) (MEK 3) (Stress-activated protein kinase kinase 2) (SAPK kinase 2) (SAPKK-2) (SAPKK2)MAP2K3 MEK3 MKK3 PRKMK3 SKK2P4673416
E3 ubiquitin-protein ligase Mdm2 (EC 6.3.2.-) (Double minute 2 protein) (Hdm2) (Oncoprotein Mdm2) (p53-binding protein Mdm2)MDM2Q0098716
E3 ubiquitin-protein ligase RFWD2 (EC 6.3.2.-) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1) (RING finger and WD repeat domain protein 2) (RING finger protein 200)RFWD2 COP1 RNF200Q8NHY216
Elongation factor 2 (EF-2)EEF2 EF2P1363916
Endoplasmic reticulum resident protein 29 (ERp29) (Endoplasmic reticulum resident protein 28) (ERp28) (Endoplasmic reticulum resident protein 31) (ERp31)ERP29 C12orf8 ERP28P3004016
Eukaryotic translation initiation factor 3 subunit G (eIF3g) (Eukaryotic translation initiation factor 3 RNA-binding subunit) (eIF-3 RNA-binding subunit) (Eukaryotic translation initiation factor 3 subunit 4) (eIF-3-delta) (eIF3 p42) (eIF3 p44)EIF3G EIF3S4O7582116
Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220)EIF4G1 EIF4F EIF4G EIF4GIQ0463716
Eukaryotic translation initiation factor 6 (eIF-6) (B(2)GCN homolog) (B4 integrin interactor) (CAB) (p27(BBP))EIF6 EIF3A ITGB4BP OK/SW-cl.27P5653716
Forkhead box protein O3 (AF6q21 protein) (Forkhead in rhabdomyosarcoma-like 1)FOXO3 FKHRL1 FOXO3AO4352416
Glycophorin-C (Glycoconnectin) (Glycophorin-D) (GPD) (Glycoprotein beta) (PAS-2') (Sialoglycoprotein D) (CD antigen CD236)GYPC GLPC GPCP0492116
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