EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Pseudouridylate synthase 7 homolog (EC 5.4.99.-)PUS7 KIAA1897Q96PZ02
Psoriasis susceptibility 1 candidate gene 2 protein (Protein SPR1)PSORS1C2 C6orf17 SPR1Q9UIG42
PTPRS protein (Receptor-type tyrosine-protein phosphatase S)PTPRSQ8NHS72
Purkinje cell protein 4-like protein 1 (PCP4-like protein 1)PCP4L1 IQM1A6NKN82
Putative aspartate aminotransferase, cytoplasmic 2 (EC 2.6.1.-) (Glutamate oxaloacetate transaminase 1-like protein 1) (Transaminase A-like protein 1)GOT1L1Q8NHS22
Putative deoxyribonuclease TATDN3 (EC 3.1.21.-)TATDN3Q17R312
Putative macrophage stimulating 1-like protein (Brain rescue factor 1) (BRF-1) (Hepatocyte growth factor-like protein homolog)MST1L D1F15S1A MST1P9 MSTP9Q2TV782
Putative pregnancy-specific beta-1-glycoprotein 7 (PS-beta-G-7) (PSBG-7) (Pregnancy-specific glycoprotein 7)PSG7Q130462
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 (EC 3.1.3.16) (RNA polymerase II-associated protein 2)RPAP2 C1orf82Q8IXW52
Putative RNA-binding protein Luc7-like 2LUC7L2 CGI-59 CGI-74Q9Y3832
Putative sodium-coupled neutral amino acid transporter 9 (Solute carrier family 38 member 9)SLC38A9Q8NBW42
Putative transcription factor Ovo-like 1 (hOvo1)OVOL1O147532
Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase (EC 2.1.1.205) (2'-O-ribose RNA methyltransferase TRM7 homolog) (Protein ftsJ homolog 1)FTSJ1 JM23Q9UET62
Putative uncharacterized protein (Fragment)0Q8WVM92
Putative uncharacterized protein C1orf229C1orf229Q6ZS942
Putative uncharacterized protein C8orf44C8orf44Q96CB52
Putative uncharacterized protein DKFZp434B0535DKFZp434B0535Q9H0C72
Putative uncharacterized protein DKFZp434N0335 (Fragment)DKFZp434N0335Q9UFD32
Putative uncharacterized protein DKFZp586C1324 (Fragment)DKFZp586C1324Q9UG232
Putative uncharacterized protein DKFZp686A1195DKFZp686A1195Q6MZU12
Putative uncharacterized protein DKFZp686I0746DKFZp686I0746Q6MZZ32
Putative uncharacterized protein DKFZp686J08252DKFZp686J08252Q63HJ82
Putative uncharacterized protein DKFZp686J1169DKFZp686J1169Q7Z3T92
Putative uncharacterized protein DKFZp686P15123DKFZp686P15123Q7Z3302
Putative uncharacterized protein DKFZp686P1551DKFZp686P1551Q63HP72
Putative uncharacterized protein DKFZp761E0417 (Fragment)DKFZp761E0417Q8N3U82
Putative uncharacterized protein DKFZp761J032 (Fragment)DKFZp761J032Q9NSJ52
Putative uncharacterized protein DKFZp761O17121 (cDNA, FLJ94277)DKFZp761O17121Q9BQJ32
Putative uncharacterized protein DKFZp762K123 (Fragment)DKFZp762K123Q69YP22
Putative uncharacterized protein DKFZp781C1895 (Putative uncharacterized protein DKFZp781O1323) (SMAD, mothers against DPP homolog 5 (Drosophila), isoform CRA_b) (cDNA, FLJ93932, Homo sapiens MAD, mothers against decapentaplegic homolog 5 (Drosophila) (MADH5), mRNA)DKFZp781O1323 DKFZp781C1895 SMAD5 hCG_41402Q68DB72
Putative uncharacterized protein DKFZp781D1223DKFZp781D1223Q68DA12
Putative uncharacterized protein MGC19606 (cDNA FLJ78128, highly similar to Homo sapiens IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) (IMP4), mRNA) (cDNA FLJ78357, highly similar to Homo sapiens IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) (IMP4), mRNA) (cDNA, FLJ93237, Homo sapiens U3 snoRNP protein 4 homolog (IMP4), mRNA)MGC19606Q3ZTT32
Putative uncharacterized protein PP2150PP2150Q8WY482
Putative uncharacterized protein TOM7 (TOMM7 protein) (Translocase of outer mitochondrial membrane 7 homolog (Yeast)) (Translocase of outer mitochondrial membrane 7 homolog (Yeast), isoform CRA_b)TOM7 TOMM7 hCG_1659575Q75MR52
PWWP domain-containing protein 2BPWWP2B PWWP2Q6NUJ52
PX domain-containing protein kinase-like protein (Modulator of Na,K-ATPase) (MONaKA)PXKQ7Z7A42
Pygopus homolog 2PYGO2 PP7910Q9BRQ02
Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 (EC 1.8.1.-)PYROXD1Q8WU102
Pyridoxal phosphate phosphatase (PLP phosphatase) (EC 3.1.3.3) (EC 3.1.3.74) (Chronophin)PDXP CIN PLP PLPPQ96GD02
Queuine tRNA-ribosyltransferase subunit QTRTD1 (EC 2.4.2.29) (Queuine tRNA-ribosyltransferase domain-containing protein 1)QTRTD1Q9H9742
R-spondin-3 (Protein with TSP type-1 repeat) (hPWTSR) (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2)RSPO3 PWTSR THSD2Q9BXY42
R3H domain-containing protein 4R3HDM4 C19orf22Q96D702
Rab effector MyRIP (Exophilin-8) (Myosin-VIIa- and Rab-interacting protein) (Synaptotagmin-like protein lacking C2 domains C) (SlaC2-c) (Slp homolog lacking C2 domains c)MYRIP SLAC2CQ8NFW92
Rab-like protein 2BRABL2BQ9UNT12
Rab3 GTPase-activating protein catalytic subunit (RAB3 GTPase-activating protein 130 kDa subunit) (Rab3-GAP p130) (Rab3-GAP)RAB3GAP1 KIAA0066 RAB3GAPQ150422
RAB40C, member RAS oncogene familyRAB40CQ6PIU52
Radial spoke head 1 homolog (Cancer/testis antigen 79) (CT79) (Male meiotic metaphase chromosome-associated acidic protein) (Meichroacidin) (Testis-specific gene A2 protein)RSPH1 TSA2 TSGA2Q8WYR42
Radical S-adenosyl methionine domain-containing protein 2 (Cytomegalovirus-induced gene 5 protein) (Viperin) (Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible)RSAD2 CIG5Q8WXG12
Ral GTPase-activating protein subunit beta (p170)RALGAPB KIAA1219Q86X102
RAN binding protein 3 isoform RANBP3-a variant (Fragment)RANBP3Q53GE12
Ran guanine nucleotide release factor (RanGNRF) (Ran-binding protein MOG1)RANGRF MOG1 RANGNRF HSPC165 HSPC236 MDS5Q9HD472
RanBP2-like and GRIP domain-containing protein 3RGPD3 RGP3A6NKT72
Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2)RAPGEF6 PDZGEF2Q8TEU72
Rap1 GTPase-activating protein 2 (Rap1GAP2) (GTPase-activating Rap/Ran-GAP domain-like protein 4)RAP1GAP2 GARNL4 KIAA1039 RAP1GA2Q684P52
RARA protein (Retinoic acid nuclear receptor alpha variant 1) (Retinoic acid receptor, alpha, isoform CRA_c) (cDNA, FLJ92939, Homo sapiens retinoic acid receptor, alpha (RARA), mRNA)RARA NR1B1 hCG_2007196Q6I9R72
Ras association domain-containing protein 1RASSF1 RDA32Q9NS232
Ras GTPase-activating protein 2 (GTPase-activating protein 1m) (GAP1m)RASA2 GAP1M RASGAPQ152832
RAS guanyl-releasing protein 2 (Calcium and DAG-regulated guanine nucleotide exchange factor I) (CalDAG-GEFI) (Cdc25-like protein) (hCDC25L) (F25B3.3 kinase-like protein)RASGRP2 CDC25L MCG7Q7LDG72
Ras-like protein family member 10B (Ras-like protein VTS58635) (Ras-related protein 17) (RRP17)RASL10BQ96S792
Ras-like protein family member 11ARASL11AQ6T3102
Ras-like protein family member 11BRASL11BQ9BPW52
Ras-related GTP-binding protein B (Rag B) (RagB)RRAGBQ5VZM22
Ras-related GTP-binding protein D (Rag D) (RagD)RRAGDQ9NQL22
Ras-related protein Rab-11B (GTP-binding protein YPT3)RAB11B YPT3Q159072
Ras-related protein Rab-15RAB15P591902
Ras-related protein Rab-17RAB17Q9H0T72
Ras-related protein Rab-18RAB18Q9NP722
Ras-related protein Rab-25 (CATX-8)RAB25 CATX8P577352
Ras-related protein Rab-2BRAB2BQ8WUD12
Ras-related protein Rab-36RAB36O957552
Ras-related protein Rab-38 (Melanoma antigen NY-MEL-1)RAB38P577292
Ras-related protein Rab-40A (SOCS box-containing protein RAR2A) (Protein Rar-2)RAB40AQ8WXH62
Ras-related protein Rab-40C (Rar-like protein) (Ras-like protein family member 8C) (SOCS box-containing protein RAR3)RAB40C RARL RASL8CQ96S212
Ras-related protein Rab-7L1 (Rab-7-like protein 1) (Ras-related protein Rab-29)RAB29 RAB7L1O149662
Ras-specific guanine nucleotide-releasing factor 1 (Ras-GRF1) (Guanine nucleotide-releasing protein) (GNRP) (Ras-specific nucleotide exchange factor CDC25)RASGRF1 CDC25 GNRP GRF1Q139722
Ras-specific guanine nucleotide-releasing factor RalGPS2 (Ral GEF with PH domain and SH3-binding motif 2) (RalA exchange factor RalGPS2)RALGPS2Q86X272
RCC1 and BTB domain-containing protein 1 (Chronic lymphocytic leukemia deletion region gene 7 protein) (CLL deletion region gene 7 protein) (Regulator of chromosome condensation and BTB domain-containing protein 1)RCBTB1 CLLD7 E4.5Q8NDN92
RDX protein (Fragment)RDXQ6PKD32
Receptor expression-enhancing protein 4REEP4 C8orf20 PP432Q9H6H42
Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) (Tyrosine kinase-type cell surface receptor HER4) (p180erbB4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]ERBB4 HER4Q153032
Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1) (Serine/threonine-protein kinase RIP)RIPK1 RIP RIP1Q135462
Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containing IL-1 beta ICE-kinase) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (Tyrosine-protein kinase RIPK2) (EC 2.7.10.2)RIPK2 CARDIAK RICK RIP2 UNQ277/PRO314/PRO34092O433532
Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3)RIPK3 RIP3Q9Y5722
Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48)PTPRDP234682
Receptor-type tyrosine-protein phosphatase epsilon (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon) (EC 3.1.3.48)PTPREP234692
Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma)PTPRSQ133322
Regulating synaptic membrane exocytosis protein 3 (Nim3) (RIM3 gamma) (Rab-3-interacting molecule 3) (RIM 3)RIMS3 KIAA0237Q9UJD02
Regulating synaptic membrane exocytosis protein 4 (RIM4 gamma) (Rab3-interacting molecule 4) (RIM 4)RIMS4 C20orf190Q9H4262
Regulator of cell cycle RGCC (Response gene to complement 32 protein) (RGC-32)RGCC C13orf15 RGC32Q9H4X12
Regulator of G-protein signaling 20 (RGS20) (Gz-selective GTPase-activating protein) (G(z)GAP) (Gz-GAP) (Regulator of G-protein signaling Z1) (Regulator of Gz-selective protein signaling 1)RGS20 RGSZ1 ZGAP1O760812
Regulator of G-protein signaling 3 (RGP3) (RGS3)RGS3P497962
Regulator of microtubule dynamics protein 2 (RMD-2) (hRMD-2) (Protein FAM82A1)RMDN2 FAM82A FAM82A1 BLOCK18 UNQ9371/PRO34163Q96LZ72
Regulatory solute carrier protein family 1 member 1 (Transporter regulator RS1) (hRS1)RSC1A1Q926812
Relaxin receptor 2 (G-protein coupled receptor 106) (G-protein coupled receptor affecting testicular descent) (Leucine-rich repeat-containing G-protein coupled receptor 8) (Relaxin family peptide receptor 2)RXFP2 GPR106 GREAT LGR8Q8WXD02
Relaxin-3 receptor 2 (RLN3 receptor 2) (G-protein coupled receptor 100) (G-protein coupled receptor GPCR142) (Insulin-like peptide INSL5 receptor) (Relaxin family peptide receptor 4)RXFP4 GPR100 RLN3R2Q8TDU92
Repulsive guidance molecule A (RGM domain family member A)RGMA RGMQ96B862
Required for meiotic nuclear division protein 1 homologRMND1 C6orf96Q9NWS82
Resistin-like beta (Colon and small intestine-specific cysteine-rich protein) (Colon carcinoma-related gene protein) (Cysteine-rich secreted protein A12-alpha-like 1) (Cysteine-rich secreted protein FIZZ2) (RELMbeta)RETNLB CCRG FIZZ2 HXCP2 RETNL2 UNQ408/PRO770Q9BQ082
REST corepressor 1 (Protein CoREST)RCOR1 KIAA0071 RCORQ9UKL02
Ret finger protein-like 2 (RING finger protein 79)RFPL2 RNF79O756782
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