EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Serine/threonine-protein kinase 35 (EC 2.7.11.1) (CLP-36-interacting kinase 1) (CLIK-1) (PDLIM1-interacting kinase 1) (Serine/threonine-protein kinase 35 L1)STK35 CLIK1 PDIK1 STK35L1Q8TDR22
Serine/threonine-protein kinase greatwall (GW) (GWL) (hGWL) (EC 2.7.11.1) (Microtubule-associated serine/threonine-protein kinase-like) (MAST-L)MASTL GW GWL THC2Q96GX52
Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)LATS2 KPMQ9NRM72
Serine/threonine-protein kinase LMTK1 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (Lemur tyrosine kinase 1) (p35-binding protein) (p35BP)AATK AATYK KIAA0641 LMR1 LMTK1Q6ZMQ82
Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase 1) (PAR1 homolog c) (Par-1c) (Par1c)MARK1 KIAA1477 MARKQ9P0L22
Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1)MTOR FRAP FRAP1 FRAP2 RAFT1 RAPT1P423452
Serine/threonine-protein kinase Nek10 (EC 2.7.11.1) (Never in mitosis A-related kinase 10) (NimA-related protein kinase 10)NEK10Q6ZWH52
Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Cutaneous T-cell lymphoma-associated antigen HD-CL-09) (CTCL-associated antigen HD-CL-09) (Dendritic cell-derived protein kinase) (JNK/SAPK-inhibitory kinase) (Jun kinase-inhibitory kinase) (Kinase from chicken homolog A) (hKFC-A) (Thousand and one amino acid protein 3)TAOK3 DPK JIK KDS MAP3K18Q9H2K82
Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (HsHPK) (PKU-alpha) (Tousled-like kinase 2)TLK2Q86UE82
Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2)VRK2Q86Y072
Serine/threonine-protein kinase WNK3 (EC 2.7.11.1) (Protein kinase lysine-deficient 3) (Protein kinase with no lysine 3)WNK3 KIAA1566 PRKWNK3Q9BYP72
Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase lysine-deficient 4) (Protein kinase with no lysine 4)WNK4 PRKWNK4Q96J922
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform (PP2A B subunit isoform B'-beta) (PP2A B subunit isoform B56-beta) (PP2A B subunit isoform PR61-beta) (PP2A B subunit isoform R5-beta)PPP2R5BQ151732
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A B subunit isoform B'-delta) (PP2A B subunit isoform B56-delta) (PP2A B subunit isoform PR61-delta) (PP2A B subunit isoform R5-delta)PPP2R5DQ147382
Serine/threonine/tyrosine-interacting protein (Protein tyrosine phosphatase-like protein)STYXQ8WUJ02
Serologically defined colon cancer antigen 3 (Antigen NY-CO-3)SDCCAG3Q96C922
Serologically defined colon cancer antigen 8 (Antigen NY-CO-8) (Centrosomal colon cancer autoantigen protein) (hCCCAP)SDCCAG8 CCCAP NPHP10 HSPC085Q86SQ72
Serpin B7 (Megsin) (TP55)SERPINB7O756352
SERTA domain-containing protein 1 (CDK4-binding protein p34SEI1) (SEI-1) (Transcriptional regulator interacting with the PHD-bromodomain 1) (TRIP-Br1)SERTAD1 SEI1Q9UHV22
Serum paraoxonase/lactonase 3 (EC 3.1.1.2) (EC 3.1.1.81) (EC 3.1.8.1)PON3Q151662
Sestrin-1 (p53-regulated protein PA26)SESN1 PA26 SEST1Q9Y6P52
SET and MYND domain-containing protein 4 (EC 2.1.1.-)SMYD4 KIAA1936Q8IYR22
Seven transmembrane helix receptor0Q8NGT42
Sex comb on midleg-like protein 1SCML1Q9UN302
SH2 domain-containing protein 4A (Protein SH(2)A) (Protein phosphatase 1 regulatory subunit 38)SH2D4A PPP1R38 SH2AQ9H7882
SH2B adapter protein 1 (Pro-rich, PH and SH2 domain-containing signaling mediator) (PSM) (SH2 domain-containing protein 1B)SH2B1 KIAA1299 SH2BQ9NRF22
SH2B adapter protein 3 (Lymphocyte adapter protein) (Lymphocyte-specific adapter protein Lnk) (Signal transduction protein Lnk)SH2B3 LNKQ9UQQ22
SH3 domain and tetratricopeptide repeat-containing protein 1SH3TC1Q8TE822
SH3 domain-binding protein 1 (3BP-1)SH3BP1Q9Y3L32
SH3 domain-binding protein 4 (EH-binding protein 10) (Transferrin receptor-trafficking protein)SH3BP4 BOG25 EHB10 TTPQ9P0V32
SHC SH2 domain-binding protein 1-like proteinSHCBP1L C1orf14Q9BZQ22
Sialic acid synthase (N-acetylneuraminate synthase) (EC 2.5.1.56) (N-acetylneuraminate-9-phosphate synthase) (EC 2.5.1.57) (N-acetylneuraminic acid phosphate synthase) (N-acetylneuraminic acid synthase)NANS SASQ9NR452
Sialic acid-binding Ig-like lectin 5 (Siglec-5) (CD33 antigen-like 2) (Obesity-binding protein 2) (OB-BP2) (OB-binding protein 2) (CD antigen CD170)SIGLEC5 CD33L2 OBBP2O153892
Sialin (H(+)/nitrate cotransporter) (H(+)/sialic acid cotransporter) (AST) (Membrane glycoprotein HP59) (Solute carrier family 17 member 5) (Vesicular H(+)/Aspartate-glutamate cotransporter)SLC17A5Q9NRA22
Signal peptidase complex subunit 3 (EC 3.4.-.-) (Microsomal signal peptidase 22/23 kDa subunit) (SPC22/23) (SPase 22/23 kDa subunit)SPCS3 SPC22 UNQ1841/PRO3567P610092
Signal peptide peptidase-like 2B (SPP-like 2B) (SPPL2b) (EC 3.4.23.-) (Intramembrane protease 4) (IMP-4) (Presenilin homologous protein 4) (PSH4) (Presenilin-like protein 1)SPPL2B IMP4 KIAA1532 PSL1Q8TCT72
Signal transducer and activator of transcription 5BSTAT5BP516922
Signal transduction protein CBL-C (RING finger protein 57) (SH3-binding protein CBL-3) (SH3-binding protein CBL-C)CBLC CBL3 RNF57Q9ULV82
Signal-induced proliferation-associated 1-like protein 1 (SIPA1-like protein 1) (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6-targeted protein 1)SIPA1L1 E6TP1 KIAA0440O431662
Similar to AFG3 ATPase family gene 3-like 2 (Yeast) (Fragment)0Q8TA922
Similar to calcyphosine (Fragment)0Q96ET42
Similar to collagen, type VI, alpha 3 (Fragment)0Q8N4Z12
Sine oculis-binding protein homolog (Jackson circler protein 1)SOBP JXC1A7XYQ12
SKIV2L2 protein (Fragment)SKIV2L2Q3MHC92
SLAIN motif-containing protein 1SLAIN1 C13orf32Q8ND832
Slit homolog 3 protein (Slit-3) (Multiple epidermal growth factor-like domains protein 5) (Multiple EGF-like domains protein 5)SLIT3 KIAA0814 MEGF5 SLIL2 UNQ691/PRO1336O750942
SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2) (Rho GTPase-activating protein 34)SRGAP2 ARHGAP34 FNBP2 KIAA0456 SRGAP2AO750442
Small conductance calcium-activated potassium channel protein 1 (SK1) (SKCa 1) (SKCa1) (KCa2.1)KCNN1 SKQ929522
Small conductance calcium-activated potassium channel protein 2 (SK2) (SKCa 2) (SKCa2) (KCa2.2)KCNN2Q9H2S12
Small nuclear ribonucleoprotein-associated proteinSNRPB hCG_2039421Q66K912
Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Novel nucleolar protein 73) (NNP73) (Protein Key-1A6)UTP20 DRIMO756912
SMARCA4 isoform 2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4, isoform CRA_c) (Transcription activator BRG1)SMARCA4 hCG_29955Q9HBD42
SmoothelinSMTN SMSMOP538142
Smoothelin-like protein 2SMTNL2Q2TAL52
snRNA-activating protein complex subunit 3 (SNAPc subunit 3) (Proximal sequence element-binding transcription factor subunit beta) (PSE-binding factor subunit beta) (PTF subunit beta) (Small nuclear RNA-activating complex polypeptide 3) (snRNA-activating protein complex 50 kDa subunit) (SNAPc 50 kDa subunit)SNAPC3 SNAP50Q929662
Sodium channel and clathrin linker 1 (Sodium channel-associated protein 1)SCLT1 SAP1Q96NL62
Sodium channel beta-4 subunit (Sodium channel, voltage-gated, type IV, beta, isoform CRA_b) (cDNA, FLJ95353, Homo sapiens sodium channel, voltage-gated, type IV, beta (SCN4B),mRNA)SCN4B hCG_1646677B0YJ932
Sodium channel protein type 3 subunit alpha (Sodium channel protein brain III subunit alpha) (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subtype III) (Voltage-gated sodium channel subunit alpha Nav1.3)SCN3A KIAA1356 NAC3Q9NY462
Sodium channel protein type 5 subunit alpha (HH1) (Sodium channel protein cardiac muscle subunit alpha) (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5)SCN5AQ145242
Sodium channel, voltage-gated, type II, beta (cDNA, FLJ94526, Homo sapiens sodium channel, voltage-gated, type II, beta (SCN2B),mRNA)SCN2B hCG_41149Q5U0K82
Sodium- and chloride-dependent betaine transporter (BGT-1) (Na(+)/Cl(-) betaine/GABA transporter) (Solute carrier family 6 member 12)SLC6A12P480652
Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (Solute carrier family 6 member 9)SLC6A9P480672
Sodium-coupled monocarboxylate transporter 2 (Electroneutral sodium monocarboxylate cotransporter) (Low-affinity sodium-lactate cotransporter) (Solute carrier family 5 member 12)SLC5A12 SMCT2Q1EHB42
Sodium-dependent neutral amino acid transporter SLC6A17 (Sodium-dependent neurotransmitter transporter NTT4) (Solute carrier family 6 member 17)SLC6A17 NTT4Q9H1V82
Sodium-dependent phosphate transport protein 1 (Na(+)/PI cotransporter 1) (Na/Pi-4) (Renal Na(+)-dependent phosphate cotransporter 1) (Renal sodium-dependent phosphate transport protein 1) (Renal sodium-phosphate transport protein 1) (Sodium/phosphate cotransporter 1) (Solute carrier family 17 member 1)SLC17A1 NPT1Q149162
Sodium-independent sulfate anion transporter (Solute carrier family 26 member 11)SLC26A11Q86WA92
Sodium/bile acid cotransporter 7 (Na(+)/bile acid cotransporter 7) (Solute carrier family 10 member 7)SLC10A7 C4orf13 P7 PSEC0051Q0GE192
Sodium/hydrogen exchanger 1 (APNH) (Na(+)/H(+) antiporter, amiloride-sensitive) (Na(+)/H(+) exchanger 1) (NHE-1) (Solute carrier family 9 member 1)SLC9A1 APNH1 NHE1P196342
Sodium/hydrogen exchanger 10 (Na(+)/H(+) exchanger 10) (NHE-10) (Solute carrier family 9 member 10) (Solute carrier family 9 member C1) (Sperm-specific Na(+)/H(+) exchanger) (sNHE)SLC9C1 SLC9A10Q4G0N82
Sodium/hydrogen exchanger 2 (Na(+)/H(+) exchanger 2) (NHE-2) (Solute carrier family 9 member 2)SLC9A2 NHE2Q9UBY02
Sodium/hydrogen exchanger 4 (Na(+)/H(+) exchanger 4) (NHE-4) (Solute carrier family 9 member 4)SLC9A4 NHE4Q6AI142
Sodium/nucleoside cotransporter 1 (Concentrative nucleoside transporter 1) (CNT 1) (hCNT1) (Na(+)/nucleoside cotransporter 1) (Sodium-coupled nucleoside transporter 1) (Solute carrier family 28 member 1)SLC28A1 CNT1O003372
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3 (Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 3) (Protein FAM77D)NKAIN3 FAM77DQ8N8D72
Sodium/potassium/calcium exchanger 6, mitochondrial (Na(+)/K(+)/Ca(2+)-exchange protein 6) (Sodium/calcium exchanger protein, mitochondrial) (Solute carrier family 24 member 6) (Solute carrier family 8 member B1)SLC8B1 NCKX6 NCLX SLC24A6Q6J4K22
Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D (Soluble scavenger protein with 5 SRCR domains) (SSc5D)SSC5DA1L4H12
Solute carrier family 1 (Glial high affinity glutamate transporter), member 3SLC1A3Q8N1692
Solute carrier family 12 member 2 (Basolateral Na-K-Cl symporter) (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1)SLC12A2 NKCC1P550112
Solute carrier family 15 member 1 (Intestinal H(+)/peptide cotransporter) (Oligopeptide transporter, small intestine isoform) (Peptide transporter 1)SLC15A1 PEPT1P460592
Solute carrier family 2 (Facilitated glucose transporter), member 1 variant (Fragment)0Q59GX22
Solute carrier family 2, facilitated glucose transporter member 8 (Glucose transporter type 8) (GLUT-8) (Glucose transporter type X1)SLC2A8 GLUT8 GLUTX1Q9NY642
Solute carrier family 20 (Phosphate transporter), member 1 (Solute carrier family 20 (Phosphate transporter), member 1, isoform CRA_a) (cDNA, FLJ93144, highly similar to Homo sapiens solute carrier family 20 (phosphate transporter), member 1 (SLC20A1), mRNA)SLC20A1 hCG_15749A7LNJ12
Solute carrier family 22 member 10 (Organic anion transporter 5)SLC22A10 OAT5Q63ZE42
Solute carrier family 22 member 5 (High-affinity sodium-dependent carnitine cotransporter) (Organic cation/carnitine transporter 2)SLC22A5 OCTN2O760822
Solute carrier family 22 member 8 (Organic anion transporter 3) (hOAT3)SLC22A8 OAT3Q8TCC72
Solute carrier family 25 member 34SLC25A34Q6PIV72
Solute carrier family 25 member 51 (Mitochondrial carrier triple repeat protein 1)SLC25A51 MCART1Q9H1U92
Solute carrier family 26 member 10SLC26A10Q8NG042
Solute carrier family 35 member F3SLC35F3Q8IY502
Solute carrier family 35 member F6 (ANT2-binding protein) (ANT2BP) (Transport and Golgi organization 9 homolog)SLC35F6 C2orf18 UNQ3047/PRO9863Q8N3572
Solute carrier family 45 member 3 (Prostate cancer-associated protein 6) (Prostein)SLC45A3 PCANAP6 PRSTQ96JT22
Solute carrier family 46 member 3SLC46A3 FKSG16Q7Z3Q12
Solute carrier family 52, riboflavin transporter, member 3 (Riboflavin transporter 2) (hRFT2)SLC52A3 C20orf54 RFT2Q9NQ402
Solute carrier organic anion transporter family member 3A1 (OATP3A1) (Organic anion transporter polypeptide-related protein 3) (OATP-RP3) (OATPRP3) (Organic anion-transporting polypeptide D) (OATP-D) (PGE1 transporter) (Sodium-independent organic anion transporter D) (Solute carrier family 21 member 11)SLCO3A1 OATP3A1 OATPD SLC21A11Q9UIG82
Solute carrier organic anion transporter family member 4C1 (OATP-H) (Organic anion transporter M1) (OATP-M1) (Solute carrier family 21 member 20)SLCO4C1 OATP4C1 OATPX SLC21A20Q6ZQN72
Somatomedin-B and thrombospondin type-1 domain-containing protein (RPE-spondin)SBSPON C8orf84 RPESPQ8IVN82
Somatostatin receptor type 2 (SS-2-R) (SS2-R) (SS2R) (SRIF-1)SSTR2P308742
Somatostatin receptor type 5 (SS-5-R) (SS5-R) (SS5R)SSTR5P353462
Sorcin (cDNA FLJ54267, moderately similar to Sorcin)SRIB4DHQ62
Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA)SORL1 C11orf32Q926732
Sorting nexin-14SNX14Q9Y5W72
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