EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Transmembrane and TPR repeat-containing protein 1TMTC1 ARG99Q8IUR52
Transmembrane channel-like protein0B3KXZ82
Transmembrane emp24 domain-containing protein 4 (Endoplasmic reticulum stress-response protein 25) (ERS25) (GMP25iso) (Putative NF-kappa-B-activating protein 156) (p24 family protein alpha-3) (p24alpha3)TMED4 ERS25Q7Z7H52
Transmembrane emp24 domain-containing protein 5 (p24 family protein gamma-2) (p24gamma2) (p28)TMED5 CGI-100 UNQ397/PRO733Q9Y3A62
Transmembrane gamma-carboxyglutamic acid protein 2 (Proline-rich gamma-carboxyglutamic acid protein 2) (Proline-rich Gla protein 2)PRRG2 PRGP2 TMG2O146692
Transmembrane protease serine 12 (EC 3.4.21.-)TMPRSS12Q86WS52
Transmembrane protease serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (CAPH2) (Membrane-type serine protease 2) (MT-SP2)TMPRSS4 TMPRSS3 UNQ776/PRO1570Q9NRS42
Transmembrane protein 102 (Common beta-chain associated protein) (CBAP)TMEM102Q8N9M52
Transmembrane protein 11, mitochondrial (Protein PM1) (Protein PMI)TMEM11 C17orf35 PM1P171522
Transmembrane protein 115 (Placental protein 6) (PP6) (Protein PL6)TMEM115 PL6 LUCA11.2Q128932
Transmembrane protein 120A (Transmembrane protein induced by tumor necrosis factor alpha)TMEM120A TMPITQ9BXJ82
Transmembrane protein 127TMEM127O752042
Transmembrane protein 132BTMEM132B KIAA1786 KIAA1906Q14DG72
Transmembrane protein 145TMEM145Q8NBT32
Transmembrane protein 14ATMEM14A C6orf73 PTD011Q9Y6G12
Transmembrane protein 150A (Transmembrane protein 150)TMEM150A TMEM150Q86TG12
Transmembrane protein 154TMEM154Q6P9G42
Transmembrane protein 165 (Transmembrane protein PT27) (Transmembrane protein TPARL)TMEM165 TPARLQ9HC072
Transmembrane protein 170ATMEM170A TMEM170Q8WVE72
Transmembrane protein 171TMEM171Q8WVE62
Transmembrane protein 176B (Protein LR8)TMEM176B LR8Q3YBM22
Transmembrane protein 184B (Putative MAPK-activating protein FM08)TMEM184B C22orf5 PSEC0108Q9Y5192
Transmembrane protein 186TMEM186 C16orf51Q96B772
Transmembrane protein 190TMEM190 MDAC1Q8WZ592
Transmembrane protein 201 (Spindle-associated membrane protein 1)TMEM201 NET5 SAMP1Q5SNT22
Transmembrane protein 214TMEM214 PP446Q6NUQ42
Transmembrane protein 217TMEM217 C6orf128Q8N7C42
Transmembrane protein 218TMEM218A2RU142
Transmembrane protein 243TMEM243 C7orf23Q9BU792
Transmembrane protein 26TMEM26Q6ZUK42
Transmembrane protein 50A (Small membrane protein 1)TMEM50A SMP1 UNQ386/PRO718O958072
Transmembrane protein 68TMEM68Q96MH62
Transmembrane protein 71TMEM71Q6P5X72
Transmembrane protein 79TMEM79Q9BSE22
Transmembrane protein 87BTMEM87BQ96K492
Transmembrane protein 92TMEM92 UNQ5801/PRO19608Q6UXU62
Transmembrane protein C16orf54C16orf54 UNQ9389/PRO34280Q6UWD82
Transmembrane protein C19orf77C19orf77 HSPC323O752642
Treacle protein (Treacher Collins syndrome protein)TCOF1Q134282
Trefoil factor 3 (Intestinal trefoil factor) (hITF) (Polypeptide P1.B) (hP1.B)TFF3 ITF TFIQ076542
Treslin (TopBP1-interacting checkpoint and replication regulator) (TopBP1-interacting, replication-stimulating protein)TICRR C15orf42Q7Z2Z12
Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase) (SINK) (p65-interacting inhibitor of NF-kappa-B)TRIB3 C20orf97 NIPK SKIP3 TRB3Q96RU72
Trichoplein keratin filament-binding protein (Protein TCHP) (Mitochondrial protein with oncostatic activity) (Mitostatin) (Tumor suppressor protein)TCHPQ9BT922
Trimeric intracellular cation channel type A (TRIC-A) (TRICA) (Transmembrane protein 38A)TMEM38AQ9H6F22
Tripartite motif-containing 15 (cDNA FLJ75016, highly similar to Homo sapiens tripartite motif-containing 15 (TRIM15), transcript variant 1, mRNA)TRIM15 hCG_23773Q5SRL02
Tripartite motif-containing 37, isoform CRA_b (Tripartite motif-containing 37, isoform CRA_c) (cDNA FLJ75453, highly similar to Homo sapiens tripartite motif-containing 37 (TRIM37), transcript variant 2, mRNA)TRIM37 hCG_1819317A8K0V92
Tripartite motif-containing protein 43TRIM43Q96BQ32
Tripartite motif-containing protein 49D1 (Tripartite motif-containing protein 49-like protein) (Tripartite motif-containing protein 49D2 pseudogene)TRIM49D1 TRIM49L TRIM49L1; TRIM49D2PC9J1S82
Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88)TRIM5 RNF88Q9C0352
Tripartite motif-containing protein 51 (SPRY domain-containing protein 5)TRIM51 SPRYD5Q9BSJ12
Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF-2) (MuRF2) (RING finger protein 29)TRIM55 MURF2 RNF29Q9BYV62
Tripartite motif-containing protein 59 (RING finger protein 104) (Tumor suppressor TSBF-1)TRIM59 RNF104 TRIM57 TSBF1Q8IWR12
Tripartite motif-containing protein 6 (RING finger protein 89)TRIM6 RNF89Q9C0302
TRMT1-like protein (EC 2.1.1.-)TRMT1L C1orf25 TRM1L MSTP070Q7Z2T52
tRNA (guanine(10)-N2)-methyltransferase homolog (EC 2.1.1.-) (tRNA guanosine-2'-O-methyltransferase TRM11 homolog)TRMT11 C6orf75 MDS024Q7Z4G42
tRNA (guanine(26)-N(2))-dimethyltransferase (EC 2.1.1.216) (tRNA 2,2-dimethylguanosine-26 methyltransferase) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase)TRMT1Q9NXH92
tRNA (guanine(37)-N1)-methyltransferase (EC 2.1.1.228) (M1G-methyltransferase) (tRNA [GM37] methyltransferase) (tRNA methyltransferase 5 homolog)TRMT5 KIAA1393 TRM5Q32P412
tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like (EC 1.3.1.-) (tRNA-dihydrouridine synthase 1-like)DUS1LQ6P1R42
Troponin C, slow skeletal and cardiac muscles (TN-C)TNNC1 TNNCP633162
Troponin I, slow skeletal muscle (Troponin I, slow-twitch isoform)TNNI1P192372
Troponin T, slow skeletal muscle (TnTs) (Slow skeletal muscle troponin T) (sTnT)TNNT1 TNTP138052
Tryptase delta (EC 3.4.21.59) (Delta-tryptase) (HmMCP-3-like tryptase III) (Mast cell mMCP-7-like) (Tryptase-3)TPSD1Q9BZJ32
Tryptase gamma (EC 3.4.21.-) (Serine protease 31) (Transmembrane tryptase) [Cleaved into: Tryptase gamma light chain; Tryptase gamma heavy chain]TPSG1 PRSS31 TMTQ9NRR22
Tryptophan 2,3-dioxygenase (TDO) (EC 1.13.11.11) (Tryptamin 2,3-dioxygenase) (Tryptophan oxygenase) (TO) (TRPO) (Tryptophan pyrrolase) (Tryptophanase)TDO2 TDOP487752
TSSK6-activating co-chaperone protein (SSTK-interacting protein) (SSTK-IP)TSACC C1orf182Q96A042
Tubby protein homologTUBP506072
Tubulin polyglutamylase TTLL7 (EC 6.-.-.-) (Testis development protein NYD-SP30) (Tubulin--tyrosine ligase-like protein 7)TTLL7Q6ZT982
Tubulin polymerization-promoting protein family member 2 (Protein p25-beta) (TPPP/p18)TPPP2 C14orf8P592822
Tubulin-specific chaperone C (Tubulin-folding cofactor C) (CFC)TBCCQ158142
Tudor domain-containing protein 10TDRD10 UNQ9380/PRO34205Q5VZ192
Tumor necrosis factor (Ligand) superfamily, member 7 (Tumor necrosis factor (Ligand) superfamily, member 7, isoform CRA_a)TNFSF7 hCG_23045Q53XX42
Tumor necrosis factor alpha-induced protein 2 (TNF alpha-induced protein 2) (Primary response gene B94 protein)TNFAIP2Q031692
Tumor necrosis factor alpha-induced protein 8 (TNF alpha-induced protein 8) (Head and neck tumor and metastasis-related protein) (MDC-3.13) (NF-kappa-B-inducible DED-containing protein) (NDED) (SCC-S2) (TNF-induced protein GG2-1)TNFAIP8O953792
Tumor necrosis factor alpha-induced protein 8-like protein 3 (TNF alpha-induced protein 8-like protein 3) (TNFAIP8-like protein 3)TNFAIP8L3Q5GJ752
Tumor necrosis factor ligand superfamily member 10 (Apo-2 ligand) (Apo-2L) (TNF-related apoptosis-inducing ligand) (Protein TRAIL) (CD antigen CD253)TNFSF10 APO2L TRAILP505912
Tumor necrosis factor ligand superfamily member 14 (Herpes virus entry mediator ligand) (HVEM-L) (Herpesvirus entry mediator ligand) (CD antigen CD258) [Cleaved into: Tumor necrosis factor ligand superfamily member 14, membrane form; Tumor necrosis factor ligand superfamily member 14, soluble form]TNFSF14 HVEML LIGHT UNQ391/PRO726O435572
Tumor necrosis factor receptor superfamily member 16 (Gp80-LNGFR) (Low affinity neurotrophin receptor p75NTR) (Low-affinity nerve growth factor receptor) (NGF receptor) (p75 ICD) (CD antigen CD271)NGFR TNFRSF16P081382
Tumor necrosis factor receptor superfamily member 1B (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (TNF-RII) (TNFR-II) (p75) (p80 TNF-alpha receptor) (CD antigen CD120b) (Etanercept) [Cleaved into: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBP-2) (TBPII)]TNFRSF1B TNFBR TNFR2P203332
Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor)EDA2R TNFRSF27 XEDAR UNQ2448/PRO5727/PRO34080Q9HAV52
Tumor necrosis factor receptor superfamily member 6 (Apo-1 antigen) (Apoptosis-mediating surface antigen FAS) (FASLG receptor) (CD antigen CD95)FAS APT1 FAS1 TNFRSF6P254452
Tumor protein p53-inducible protein 11 (p53-induced gene 11 protein)TP53I11 PIG11O146832
Tumor suppressor p53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1)TP53BP1Q128882
Twinkle protein, mitochondrial (EC 3.6.4.12) (Progressive external ophthalmoplegia 1 protein) (T7 gp4-like protein with intramitochondrial nucleoid localization) (T7-like mitochondrial DNA helicase)PEO1 C10orf2Q96RR12
Two pore calcium channel protein 1 (Voltage-dependent calcium channel protein TPC1)TPCN1 KIAA1169 TPC1Q9ULQ12
Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase (Type 2 PtdIns-4,5-P2 4-Ptase) (EC 3.1.3.78) (PtdIns-4,5-P2 4-Ptase II) (Transmembrane protein 55A)TMEM55AQ8N4L22
Type I inositol 3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) (Inositol polyphosphate 4-phosphatase type I)INPP4AQ96PE32
Type II iodothyronine deiodinase (EC 1.97.1.10) (5DII) (DIOII) (Type 2 DI) (Type-II 5'-deiodinase)DIO2 ITDI2 TXDI2Q928132
Tyrosinase (EC 1.14.18.1) (LB24-AB) (Monophenol monooxygenase) (SK29-AB) (Tumor rejection antigen AB)TYRP146792
Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)BLKP514512
Tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (Feline sarcoma/Fujinami avian sarcoma oncogene homolog) (Proto-oncogene c-Fes) (Proto-oncogene c-Fps) (p93c-fes)FES FPSP073322
Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)FRK PTK5 RAKP426852
Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk)ITK EMT LYKQ088812
Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)JAK3P523332
Tyrosine-protein kinase PRAG1 (EC 2.7.10.2) (PEAK1-related kinase-activating pseudokinase 1) (Sugen kinase 223) (SgK223)PRAG1 SGK223Q86YV52
Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)SYKP434052
Tyrosine-protein kinase transmembrane receptor ROR2 (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2)ROR2 NTRKR2Q019742
Tyrosine-protein kinase TXK (EC 2.7.10.2) (Protein-tyrosine kinase 4) (Resting lymphocyte kinase)TXK PTK4 RLKP426812
Tyrosine-protein phosphatase non-receptor type (EC 3.1.3.48)PTPN1 hCG_37134A8K3M32
Tyrosine-protein phosphatase non-receptor type 20 (hPTPN20) (EC 3.1.3.48)PTPN20A; PTPN20BQ4JDL32
Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP) (PEST-domain phosphatase) (PEP)PTPN22 PTPN8Q9Y2R22
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