EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (EC 1.3.1.22) (SR type 1) (Steroid 5-alpha-reductase 1) (S5AR 1)SRD5A1P184051
39S ribosomal protein L45, mitochondrialMRPL45A0A087X2D51
40S ribosomal protein S21 (Fragment)RPS21 hCG_41768Q6FGH51
43 kDa receptor-associated protein of the synapse (RAPsyn) (43 kDa postsynaptic protein) (Acetylcholine receptor-associated 43 kDa protein) (RING finger protein 205)RAPSN RNF205Q137021
5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31)PRKAA2 AMPK AMPK2P546461
5'-AMP-activated protein kinase subunit gamma-1 (AMPK gamma1) (AMPK subunit gamma-1) (AMPKg)PRKAG1P546191
5'-nucleotidase, ecto (CD73)NT5EQ6NZX31
5,6-dihydroxyindole-2-carboxylic acid oxidase (DHICA oxidase) (EC 1.14.18.-) (Catalase B) (Glycoprotein 75) (Melanoma antigen gp75) (Tyrosinase-related protein 1) (TRP) (TRP-1) (TRP1)TYRP1 CAS2 TYRP TYRRPP176431
5-hydroxytryptamine (Serotonin) receptor 5A (cDNA FLJ36936 fis, clone BRACE2005395, highly similar to 5-HYDROXYTRYPTAMINE 5A RECEPTOR)HTR5A hCG_17152 tcag7.833A4D2N21
5-hydroxytryptamine receptor 1E (5-HT-1E) (5-HT1E) (S31) (Serotonin receptor 1E)HTR1EP285661
5-hydroxytryptamine receptor 2B (5-HT-2B) (5-HT2B) (Serotonin receptor 2B)HTR2BP415951
5-hydroxytryptamine receptor 3A (5-HT3-A) (5-HT3A) (5-hydroxytryptamine receptor 3) (5-HT-3) (5-HT3R) (Serotonin receptor 3A) (Serotonin-gated ion channel receptor)HTR3A 5HT3R HTR3P460981
5-hydroxytryptamine receptor 3C (5-HT3-C) (5-HT3C) (Serotonin receptor 3C)HTR3CQ8WXA81
5-hydroxytryptamine receptor 3D (5-HT3-D) (5-HT3D) (Serotonin receptor 3D)HTR3DQ70Z441
5-hydroxytryptamine receptor 5A (5-HT-5) (5-HT-5A) (5-HT5A) (Serotonin receptor 5A)HTR5AP478981
5-methylcytosine rRNA methyltransferase NSUN4 (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 4)NSUN4Q96CB91
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (6PF-2-K/Fru-2,6-P2ase 2) (PFK/FBPase 2) (6PF-2-K/Fru-2,6-P2ase heart-type isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]PFKFB2O608251
60S ribosomal export protein NMD3 (hNMD3)NMD3 CGI-07Q96D461
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase (EC 1.14.13.95) (7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase) (CYPVIIIB1) (Cytochrome P450 8B1) (Sterol 12-alpha-hydroxylase)CYP8B1 CYP12Q9UNU61
72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol 4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV)INPP5EQ9NRR61
7SK snRNA methylphosphate capping enzyme (MePCE) (EC 2.1.1.-) (Bicoid-interacting protein 3 homolog) (Bin3 homolog)MEPCE BCDIN3Q7L2J01
85/88 kDa calcium-independent phospholipase A2 (CaI-PLA2) (EC 3.1.1.4) (Group VI phospholipase A2) (GVI PLA2) (Intracellular membrane-associated calcium-independent phospholipase A2 beta) (iPLA2-beta) (Patatin-like phospholipase domain-containing protein 9) (PNPLA9)PLA2G6 PLPLA9O607331
A disintegrin and metalloproteinase with thrombospondin motifs 13 (ADAM-TS 13) (ADAM-TS13) (ADAMTS-13) (EC 3.4.24.87) (von Willebrand factor-cleaving protease) (vWF-CP) (vWF-cleaving protease)ADAMTS13 C9orf8 UNQ6102/PRO20085Q76LX81
A disintegrin and metalloproteinase with thrombospondin motifs 15 (ADAM-TS 15) (ADAM-TS15) (ADAMTS-15) (EC 3.4.24.-)ADAMTS15Q8TE581
A disintegrin and metalloproteinase with thrombospondin motifs 16 (ADAMTS16s alternative splice form)ADAMTS16Q2XQZ01
A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAM-TS 18) (ADAM-TS18) (ADAMTS-18) (EC 3.4.24.-)ADAMTS18 ADAMTS21Q8TE601
A disintegrin and metalloproteinase with thrombospondin motifs 20 (ADAM-TS 20) (ADAM-TS20) (ADAMTS-20) (EC 3.4.24.-)ADAMTS20P595101
A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAM-TS 4) (ADAM-TS4) (ADAMTS-4) (EC 3.4.24.82) (ADMP-1) (Aggrecanase-1)ADAMTS4 KIAA0688 UNQ769/PRO1563O751731
A disintegrin and metalloproteinase with thrombospondin motifs 6 (ADAM-TS 6) (ADAM-TS6) (ADAMTS-6) (EC 3.4.24.-)ADAMTS6Q9UKP51
A disintegrin and metalloproteinase with thrombospondin motifs 8 (ADAM-TS 8) (ADAM-TS8) (ADAMTS-8) (EC 3.4.24.-) (METH-2) (METH-8)ADAMTS8 METH2Q9UP791
A-kinase anchor protein 17A (AKAP-17A) (721P) (B-lymphocyte antigen) (Protein XE7) (Protein kinase A-anchoring protein 17A) (PRKA17A) (Splicing factor, arginine/serine-rich 17A)AKAP17A CXYorf3 DXYS155E SFRS17A XE7Q020401
A-kinase anchor protein 3 (AKAP-3) (A-kinase anchor protein 110 kDa) (AKAP 110) (Cancer/testis antigen 82) (CT82) (Fibrous sheath protein of 95 kDa) (FSP95) (Fibrousheathin I) (Fibrousheathin-1) (Protein kinase A-anchoring protein 3) (PRKA3) (Sperm oocyte-binding protein)AKAP3 AKAP110 SOB1O759691
A-kinase anchor protein 4 (AKAP-4) (A-kinase anchor protein 82 kDa) (AKAP 82) (hAKAP82) (Major sperm fibrous sheath protein) (HI) (Protein kinase A-anchoring protein 4) (PRKA4)AKAP4 AKAP82Q5JQC91
A-kinase anchor protein 9 (AKAP-9) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (A-kinase anchor protein 450 kDa) (AKAP 450) (AKAP 120-like protein) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP) (Protein hyperion) (Protein kinase A-anchoring protein 9) (PRKA9) (Protein yotiao)AKAP9 AKAP350 AKAP450 KIAA0803Q999961
A-kinase anchor protein SPHKAP (SPHK1-interactor and AKAP domain-containing protein) (Sphingosine kinase type 1-interacting protein)SPHKAP KIAA1678 SKIPQ2M3C71
A/G-specific adenine DNA glycosylase (EC 3.2.2.-) (MutY homolog) (hMYH)MUTYH MYHQ9UIF71
A/G-specific adenine DNA glycosylase (MutY homolog (E. coli), isoform CRA_e)MUTYH hCG_1780049E5KP261
ABC50 protein (ATP-binding cassette, sub-family F (GCN20), member 1) (ATP-binding cassette, sub-family F (GCN20), member 1, isoform CRA_a)ABCF1 ABC50 hCG_26012Q2L6I21
Abhydrolase domain-containing protein 1 (EC 3.1.1.-) (Lung alpha/beta hydrolase 1)ABHD1 LABH1Q96SE01
Abhydrolase domain-containing protein 3 (EC 3.1.1.-) (Lung alpha/beta hydrolase 3)ABHD3 LABH3Q8WU671
ACACA protein (Fragment)ACACAQ7Z5W81
Acetylcholine receptor subunit epsilonCHRNE ACHREQ048441
Achaete-scute homolog 1 (ASH-1) (hASH1) (Class A basic helix-loop-helix protein 46) (bHLHa46)ASCL1 ASH1 BHLHA46 HASH1P505531
Achaete-scute homolog 3 (ASH-3) (hASH3) (Class A basic helix-loop-helix protein 42) (bHLHa42) (bHLH transcriptional regulator Sgn-1)ASCL3 BHLHA42 HASH3 SGN1Q9NQ331
Acid-sensing ion channel 4 (ASIC4) (Amiloride-sensitive cation channel 4) (Amiloride-sensitive cation channel 4, pituitary)ASIC4 ACCN4Q96FT71
Acidic leucine-rich nuclear phosphoprotein 32 family member C (Phosphoprotein 32-related protein 1) (Tumorigenic protein pp32r1)ANP32C PP32R1O434231
Acidic repeat-containing proteinACRCQ96QF71
Acrosomal protein SP-10 (Acrosomal vesicle protein 1)ACRV1P264361
Actin filament-associated protein 1-like 1 (AFAP1-like protein 1)AFAP1L1Q8TED91
Actin, gamma-enteric smooth muscle (Alpha-actin-3) (Gamma-2-actin) (Smooth muscle gamma-actin)ACTG2 ACTA3 ACTL3 ACTSGP632671
Actin-like protein 7B (Actin-like-7-beta)ACTL7BQ9Y6141
Actin-like protein 8 (Cancer/testis antigen 57) (CT57)ACTL8Q9H5681
Actin-related protein 10 (Actin-related protein 11) (hARP11)ACTR10 ACTR11 ARP11Q9NZ321
Actin-related protein 3-beta variant (Fragment)0Q59GD51
Actin-related protein T1 (ARP-T1)ACTRT1 ARPT1 HSD27Q8TDG21
Actin-related protein T3 (ARP-T3) (Actin-related protein M1)ACTRT3 ARPM1Q9BYD91
Activating molecule in BECN1-regulated autophagy protein 1AMBRA1 KIAA1736Q9C0C71
Activator of basal transcription 1 (hABT1) (Basal transcriptional activator)ABT1Q9ULW31
Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I)ACVR1 ACVRLK2Q047711
Activin receptor type-1C (EC 2.7.11.30) (Activin receptor type IC) (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7)ACVR1C ALK7Q8NER51
Acyl-CoA synthetase short-chain family member 3, mitochondrial (EC 6.2.1.1) (Acyl-CoA synthetase short-chain family member 3)ACSS3Q9H6R31
Acyl-Coenzyme A dehydrogenase family, member 8, isoform CRA_a (Isobutyryl-CoA dehydrogenase, mitochondrial) (cDNA FLJ90159 fis, clone HEMBB1002465, weakly similar to ACYL-COA DEHYDROGENASE (EC 1.3.99.-))ACAD8 hCG_37259Q6ZWP61
Acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain (Mitochondrial short-chain specific acyl-CoA dehydrogenase)ACADS hCG_27359E5KSD51
Acyl-coenzyme A synthetase ACSM1, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 1) (Butyrate--CoA ligase 1) (Butyryl-coenzyme A synthetase 1) (Lipoate-activating enzyme) (Middle-chain acyl-CoA synthetase 1)ACSM1 BUCS1 LAE MACS1Q08AH11
Acyl-coenzyme A synthetase ACSM6, mitochondrial (EC 6.2.1.2)ACSM6 C10orf129Q6P4611
Acyloxyacyl hydrolase (EC 3.1.1.77) [Cleaved into: Acyloxyacyl hydrolase small subunit; Acyloxyacyl hydrolase large subunit]AOAHP280391
AD021 protein (C4orf18 protein) (Putative uncharacterized protein DKFZp434L142)AD021 C4orf18 DKFZp434L142Q9NYZ01
ADAM metallopeptidase domain 17 (ADAM metallopeptidase domain 17 (Tumor necrosis factor, alpha, converting enzyme), isoform CRA_b) (ADAM metallopeptidase domain 18)ADAM17 ADAM18 hCG_23065B2RNB21
ADAM8 protein (cDNA, FLJ93272, highly similar to Homo sapiens a disintegrin and metalloproteinase domain 8 (ADAM8),mRNA)ADAM8Q14C661
ADAMTS-like protein 2 (ADAMTSL-2)ADAMTSL2 KIAA0605Q86TH11
ADAMTS3 protein (Fragment)ADAMTS3Q96AY51
ADAMTS8 protein (Fragment)ADAMTS8Q5FWF11
Adaptor-related protein complex 1, gamma 1 subunitAP1G1Q8IY971
Adaptor-related protein complex 1, sigma 2 subunit, isoform CRA_e (Clathrin-associated protein 19)AP1S2 hCG_1982256Q549M91
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (PAPS transporter 1) (Putative MAPK-activating protein PM15) (Putative NF-kappa-B-activating protein 48) (Solute carrier family 35 member B2)SLC35B2 PAPST1 PSEC0149Q8TB611
Adenosine deaminase-like protein (EC 3.5.4.-)ADALQ6DHV71
Adenosine receptor A1ADORA1P305421
Adenosine receptor A2bADORA2BP292751
Adenosine receptor A3ADORA3 UNQ1931/PRO4406P337651
Adenylate cyclase type 3 (EC 4.6.1.1) (ATP pyrophosphate-lyase 3) (Adenylate cyclase type III) (AC-III) (Adenylate cyclase, olfactive type) (Adenylyl cyclase 3) (AC3)ADCY3 KIAA0511O602661
Adenylate cyclase type 7 (EC 4.6.1.1) (ATP pyrophosphate-lyase 7) (Adenylate cyclase type VII) (Adenylyl cyclase 7)ADCY7 KIAA0037P518281
Adenylate cyclase type 8 (EC 4.6.1.1) (ATP pyrophosphate-lyase 8) (Adenylate cyclase type VIII) (Adenylyl cyclase 8) (AC8) (Ca(2+)/calmodulin-activated adenylyl cyclase)ADCY8P401451
Adenylate cyclase type 9 (EC 4.6.1.1) (ATP pyrophosphate-lyase 9) (Adenylate cyclase type IX) (Adenylyl cyclase 9)ADCY9 KIAA0520O605031
Adipocyte enhancer-binding protein 1 (AE-binding protein 1) (Aortic carboxypeptidase-like protein)AEBP1 ACLPQ8IUX71
ADP-ribosylation factor GTPase-activating protein 2 (ARF GAP 2) (GTPase-activating protein ZNF289) (Zinc finger protein 289)ARFGAP2 ZNF289 Nbla10535Q8N6H71
ADP-ribosylation factor-like 5B (ADP-ribosylation factor-like protein 5B)ARL5B hCG_37808B0YIW91
ADP-ribosylation factor-like protein 11 (ADP-ribosylation factor-like tumor suppressor protein 1)ARL11 ARLTS1Q969Q41
ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1)ARL13B ARL2L1Q3SXY81
ADP-ribosylation factor-like protein 15 (ADP-ribosylation factor-related protein 2) (ARF-related protein 2)ARL15 ARFRP2Q9NXU51
ADP/ATP translocase 4 (ADP,ATP carrier protein 4) (Adenine nucleotide translocator 4) (ANT 4) (Solute carrier family 25 member 31) (Sperm flagellar energy carrier protein)SLC25A31 AAC4 ANT4 SFECQ9H0C21
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6)MLLT4 AF6P551961
Aggrecan core proteinACANE7EX881
Aggrecan core proteinACANE7ENV91
Agmatinase, mitochondrial (EC 3.5.3.11) (Agmatine ureohydrolase) (AUH)AGMATQ9BSE51
AKAP12 protein (Fragment)AKAP12Q86TJ91
AKAP5 protein (Fragment)AKAP5Q6PG461
Alcohol dehydrogenase 5 (Class III), chi polypeptide (Alcohol dehydrogenase 5 (Class III), chi polypeptide, isoform CRA_a) (cDNA, FLJ92689, highly similar to Homo sapiens alcohol dehydrogenase 5 (class III), chi polypeptide(ADH5), mRNA)ADH5 hCG_41483Q6IRT11
ALKBH1 protein (Fragment)ALKBH1Q5XKL01
Alkylated DNA repair protein alkB homolog 8 (EC 1.14.11.-) (Probable alpha-ketoglutarate-dependent dioxygenase ABH8) (S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8) (tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8) (EC 2.1.1.229)ALKBH8 ABH8Q96BT71
Allantoicase, isoform CRA_a (Probable allantoicase) (cDNA FLJ60951, highly similar to Probable allantoicase (EC 3.5.3.4))ALLC hCG_15830B4DY771
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