EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180)DOCK1Q141851
Dedicator of cytokinesis protein 10 (Zizimin-3)DOCK10 KIAA0694 ZIZ3Q96BY61
Dedicator of cytokinesis protein 2DOCK2 KIAA0209Q926081
Dehydrogenase/reductase (SDR family) member 4 like 2A3DHRS4L2D5KJA11
Dehydrogenase/reductase SDR family member 7B (EC 1.1.-.-)DHRS7B CGI-93 UNQ212/PRO238Q6IAN01
Dehydrogenase/reductase SDR family member 9 (EC 1.1.-.-) (3-alpha hydroxysteroid dehydrogenase) (3-alpha-HSD) (NADP-dependent retinol dehydrogenase/reductase) (RDH-E2) (RDHL) (Short-chain dehydrogenase/reductase retSDR8) (Tracheobronchial epithelial cell-specific retinol dehydrogenase) (RDH-TBE)DHRS9 UNQ835/PRO1773Q9BPW91
Dehydrogenase/reductase SDR family member on chromosome X (EC 1.1.-.-) (DHRSXY)DHRSX CXorf11 DHRS5X UNQ6508/PRO21433Q8N5I41
Deleted in autism protein 1 (Golgi Protein of 49 kDa) (GoPro49) (Hypoxia and AKT-induced stem cell factor) (HASF)C3orf58 DIA1Q8NDZ41
Delta and Notch-like epidermal growth factor-related receptorDNER BET UNQ262/PRO299Q8NFT81
Delta(14)-sterol reductase (Delta-14-SR) (EC 1.3.1.70) (Another new gene 1 protein) (C-14 sterol reductase) (Putative sterol reductase SR-1) (Sterol C14-reductase) (Transmembrane 7 superfamily member 2)TM7SF2 ANG1O760621
Delta-1-pyrroline-5-carboxylate synthase (P5CS) (Aldehyde dehydrogenase family 18 member A1) [Includes: Glutamate 5-kinase (GK) (EC 2.7.2.11) (Gamma-glutamyl kinase); Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)]ALDH18A1 GSAS P5CS PYCSP548861
Delta-like 1 homolog (Drosophila)DLK1Q969Y61
Delta-like protein 1 (Drosophila Delta homolog 1) (Delta1) (H-Delta-1)DLL1 UNQ146/PRO172O005481
Dendritic cell nuclear protein 1DCNP1 C5orf20Q8TF631
DENN domain-containing protein 1A (Connecdenn 1) (Connecdenn) (Protein FAM31A)DENND1A FAM31A KIAA1608Q8TEH31
Dentin matrix acidic phosphoprotein 1 (DMP-1) (Dentin matrix protein 1)DMP1Q133161
Dentin sialophosphoprotein [Cleaved into: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)]DSPPQ9NZW41
Deoxynucleoside kinase0F5CTF31
DEP domain-containing mTOR-interacting protein (DEP domain-containing protein 6)DEPTOR DEPDC6Q8TB451
DEP domain-containing protein 1B (HBV X-transactivated gene 8 protein) (HBV XAg-transactivated protein 8)DEPDC1B XTP8Q8WUY91
DEP domain-containing protein 5DEPDC5 KIAA0645O751401
Derlin-2 (Degradation in endoplasmic reticulum protein 2) (DERtrin-2) (Der1-like protein 2) (F-LAN-1) (F-LANa)DERL2 DER2 FLANA CGI-101 SBBI53Q9GZP91
Dermokine (Dermokine epsilon) (Dermokine epsilon-1) (Dermokine epsilon-3)DMKNA3EZ841
DesminDESP176611
Desmocollin 1, isoform CRA_b (Desmocollin 1b)DSC1 hCG_25474Q9HB001
Desmocollin-2 (Cadherin family member 2) (Desmocollin-3) (Desmosomal glycoprotein II) (Desmosomal glycoprotein III)DSC2 CDHF2 DSC3Q024871
Desmoglein-4 (Cadherin family member 13)DSG4 CDHF13Q86SJ61
DET1 homolog (De-etiolated-1 homolog)DET1Q7L5Y61
Deubiquitinating protein VCIP135 (EC 3.4.19.12) (Valosin-containing protein p97/p47 complex-interacting protein 1) (Valosin-containing protein p97/p47 complex-interacting protein p135) (VCP/p47 complex-interacting 135-kDa protein)VCPIP1 KIAA1850 VCIP135Q96JH71
Developmental pluripotency-associated protein 3 (Stella-related protein)DPPA3 STELLARQ6W0C51
Developmental pluripotency-associated protein 4DPPA4Q7L1901
DHX57 protein (Fragment)DHX57Q8N4U21
Diacylglycerol kinase gamma (DAG kinase gamma) (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma)DGKG DAGK3P496191
Diacylglycerol kinase iota (DAG kinase iota) (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota)DGKIO759121
Diacylglycerol O-acyltransferase 1 (EC 2.3.1.20) (ACAT-related gene product 1) (Acyl-CoA retinol O-fatty-acyltransferase) (ARAT) (Retinol O-fatty-acyltransferase) (EC 2.3.1.76) (Diglyceride acyltransferase)DGAT1 AGRP1 DGATO759071
Dickkopf-like protein 1DKK1I1W6601
Dickkopf-related protein 4 (Dickkopf-4) (Dkk-4) (hDkk-4) [Cleaved into: Dickkopf-related protein 4 short form]DKK4Q9UBT31
Diffuse panbronchiolitis critical region protein 1DPCR1 C6orf37 PBLTQ3MIW91
Dihydrofolate reductase, mitochondrial (EC 1.5.1.3) (Dihydrofolate reductase-like protein 1)DHFRL1 DHFRP4Q86XF01
Dihydropyrimidinase-related protein 4 (DRP-4) (Collapsin response mediator protein 3) (CRMP-3) (UNC33-like phosphoprotein 4) (ULIP-4)DPYSL4 CRMP3 ULIP4O145311
Dihydropyrimidine dehydrogenase [NADP(+)] (DHPDHase) (DPD) (EC 1.3.1.2) (Dihydrothymine dehydrogenase) (Dihydrouracil dehydrogenase)DPYDQ128821
Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (Dimethylaniline oxidase 3) (FMO II) (FMO form 2) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Trimethylamine monooxygenase) (EC 1.14.13.148)FMO3P315131
DIP2C protein (Fragment)DIP2CQ86XV31
Dipeptidase 1 (EC 3.4.13.19) (Dehydropeptidase-I) (Microsomal dipeptidase) (Renal dipeptidase) (hRDP)DPEP1 MDP RDPP164441
Diphosphoinositol polyphosphate phosphohydrolase 3-beta (DIPP-3-beta) (DIPP3-beta) (hDIPP3beta) (EC 3.6.1.52) (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-beta) (Diadenosine hexaphosphate hydrolase (AMP-forming)) (EC 3.6.1.60) (Nucleoside diphosphate-linked moiety X motif 11) (Nudix motif 11) (hAps1)NUDT11 APS1 DIPP3BQ96G611
Diphthamide biosynthesis protein 1 (DPH1 homolog) (HsDph1) (Diphthamide biosynthesis protein 2 homolog-like 1) (DPH-like 1) (DPH2-like 1) (Diphthamide biosynthesis protein 2-like) (Ovarian cancer-associated gene 1 protein)DPH1 DPH2L DPH2L1 OVCA1Q9BZG81
DIS3-like exonuclease 2 (hDIS3L2) (EC 3.1.13.-)DIS3L2 FAM6AQ8IYB71
Discoidin, CUB and LCCL domain-containing protein 1DCBLD1Q8N8Z61
Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (CDw156) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c)ADAM10 KUZ MADMO146721
Disintegrin and metalloproteinase domain-containing protein 20 (ADAM 20) (EC 3.4.24.-)ADAM20O435061
Disintegrin and metalloproteinase domain-containing protein 22 (ADAM 22) (Metalloproteinase-disintegrin ADAM22-3) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2)ADAM22 MDC2Q9P0K11
Disintegrin and metalloproteinase domain-containing protein 28 (ADAM 28) (EC 3.4.24.-) (Epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II) (eMDC II) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein L) (MDC-L)ADAM28 ADAM23 MDCLQ9UKQ21
Disintegrin and metalloproteinase domain-containing protein 7 (ADAM 7) (Sperm maturation-related glycoprotein GP-83)ADAM7 GP83Q9H2U91
Disintegrin and metalloproteinase domain-containing protein 9 (ADAM 9) (EC 3.4.24.-) (Cellular disintegrin-related protein) (Meltrin-gamma) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase)ADAM9 KIAA0021 MCMP MDC9 MLTNGQ134431
Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (hGKAP) (PSD-95/SAP90-binding protein 1) (SAP90/PSD-95-associated protein 1) (SAPAP1)DLGAP1 DAP1 GKAPO144901
Disks large-associated protein 3 (DAP-3) (PSD-95/SAP90-binding protein 3) (SAP90/PSD-95-associated protein 3) (SAPAP3)DLGAP3 DAP3O958861
Disks large-associated protein 5 (DAP-5) (Discs large homolog 7) (Disks large-associated protein DLG7) (Hepatoma up-regulated protein) (HURP)DLGAP5 DLG7 KIAA0008Q153981
Disrupted in schizophrenia 1 proteinDISC1 KIAA0457Q9NRI51
Distal-less homeobox 2 (Putative uncharacterized protein DLX2) (cDNA FLJ75693, highly similar to Homo sapiens distal-less homeo box 2 (DLX2), mRNA)DLX2 hCG_16788Q53QU71
DNA annealing helicase and endonuclease ZRANB3 (Annealing helicase 2) (AH2) (Zinc finger Ran-binding domain-containing protein 3) [Includes: DNA annealing helicase ZRANB3 (EC 3.6.4.-); Endonuclease ZRANB3 (EC 3.1.-.-)]ZRANB3Q5FWF41
DNA cross-link repair 1A protein (SNM1 homolog A) (hSNM1) (hSNM1A)DCLRE1A KIAA0086 SNM1 SNM1AQ6PJP81
DNA damage-regulated autophagy modulator protein 2 (Transmembrane protein 77)DRAM2 TMEM77 PSEC0031 UNQ154/PRO180Q6UX651
DNA excision repair protein ERCC-6 (EC 3.6.4.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB)ERCC6 CSBQ034681
DNA helicase MCM9 (hMCM9) (EC 3.6.4.12) (Mini-chromosome maintenance deficient domain-containing protein 1) (Minichromosome maintenance 9)MCM9 C6orf61 MCMDC1Q9NXL91
DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3)LIG3P499161
DNA nucleotidylexotransferase (EC 2.7.7.31) (Terminal addition enzyme) (Terminal deoxynucleotidyltransferase) (Terminal transferase)DNTT TDTP040531
DNA polymerase alpha catalytic subunit (EC 2.7.7.7) (DNA polymerase alpha catalytic subunit p180)POLA1 POLAP098841
DNA polymerase delta catalytic subunit (EC 2.7.7.7) (DNA polymerase subunit delta p125)POLD1 POLDP283401
DNA polymerase epsilon catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A)POLE POLE1Q078641
DNA polymerase iota (EC 2.7.7.7) (Eta2) (RAD30 homolog B)POLI RAD30BQ9UNA41
DNA polymerase theta (EC 2.7.7.7) (DNA polymerase eta)POLQ POLHO754171
DNA polymerase theta variant (Fragment)0Q59EE41
DNA primase large subunit (EC 2.7.7.-) (DNA primase 58 kDa subunit) (p58)PRIM2 PRIM2AP496431
DNA repair protein complementing XP-A cells (Xeroderma pigmentosum group A-complementing protein)XPA XPACP230251
DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-)RAD50Q928781
DNA repair protein RAD51 homolog 1 (HsRAD51) (hRAD51) (RAD51 homolog A)RAD51 RAD51A RECAQ066091
DNA repair protein RAD51 homolog 2 (R51H2) (RAD51 homolog B) (Rad51B) (RAD51-like protein 1)RAD51B RAD51L1 REC2O153151
DNA repair-scaffolding protein (Scaffolding protein involved in DNA repair)SPIDR KIAA0146Q141591
DNA replication licensing factor MCM3 (MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), isoform CRA_b) (cDNA FLJ55599, highly similar to DNA replication licensing factor MCM3)MCM3 hCG_22498B4DWW41
DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha)TOP3A TOP3Q134721
DNA transposase THAP9 (EC 2.7.7.-) (THAP domain-containing protein 9) (hTh9)THAP9Q9H5L61
DNA-binding protein Ikaros (Ikaros family zinc finger protein 1) (Lymphoid transcription factor LyF-1)IKZF1 IK1 IKAROS LYF1 ZNFN1A1Q134221
DNA-binding protein SMUBP-2 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase IGHMBP2) (Glial factor 1) (GF-1) (Immunoglobulin mu-binding protein 2)IGHMBP2 SMBP2 SMUBP2P389351
DNA-directed RNA polymerase (EC 2.7.7.6)DKFZp686D10173Q7Z3R81
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5 (DNA-directed RNA polymerase II subunit M, isoforms 4/5)POLR2M GRINL1AQ6EEV41
DNA-directed RNA polymerase III subunit RPC4 (RNA polymerase III subunit C4) (DNA-directed RNA polymerase III subunit D) (Protein BN51) (RNA polymerase III 47 kDa subunit) (RPC53 homolog)POLR3D BN51 BN51TP054231
DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6)POLRMTO004111
DnaJ (Hsp40) homolog, subfamily B, member 2, isoform CRA_a (Putative uncharacterized protein DNAJB2) (cDNA, FLJ93128, Homo sapiens DnaJ (Hsp40) homolog, subfamily B, member 2 (DNAJB2), mRNA)DNAJB2 hCG_15578Q53QD71
DnaJ homolog subfamily B member 11 (APOBEC1-binding protein 2) (ABBP-2) (DnaJ protein homolog 9) (ER-associated DNAJ) (ER-associated Hsp40 co-chaperone) (Endoplasmic reticulum DNA J domain-containing protein 3) (ER-resident protein ERdj3) (ERdj3) (ERj3p) (HEDJ) (Human DnaJ protein 9) (hDj-9) (PWP1-interacting protein 4)DNAJB11 EDJ ERJ3 HDJ9 PSEC0121 UNQ537/PRO1080Q9UBS41
DnaJ homolog subfamily C member 10 (EC 1.8.4.-) (Endoplasmic reticulum DNA J domain-containing protein 5) (ER-resident protein ERdj5) (ERdj5) (Macrothioredoxin) (MTHr)DNAJC10 ERDJ5 UNQ495/PRO1012Q8IXB11
DnaJ homolog subfamily C member 12 (J domain-containing protein 1)DNAJC12 JDP1Q9UKB31
DnaJ homolog subfamily C member 14 (DnaJ protein homolog 3) (Dopamine receptor-interacting protein of 78 kDa) (DRIP78) (Human DnaJ protein 3) (hDj-3)DNAJC14 DRIP78 HDJ3Q6Y2X31
DnaJ homolog subfamily C member 21 (DnaJ homolog subfamily A member 5) (Protein GS3)DNAJC21 DNAJA5Q5F1R61
DnaJ homolog subfamily C member 25DNAJC25Q9H1X31
DnaJ homolog subfamily C member 3 (Endoplasmic reticulum DNA J domain-containing protein 6) (ER-resident protein ERdj6) (ERdj6) (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor of 58 kDa) (Protein kinase inhibitor p58)DNAJC3 P58IPK PRKRIQ132171
DnaJ homolog subfamily C member 30 (Williams-Beuren syndrome chromosomal region 18 protein)DNAJC30 WBSCR18Q96LL91
DNAL4 protein (Dynein, axonemal, light polypeptide 4) (Proliferation-inducing protein 27) (cDNA FLJ76544, highly similar to Homo sapiens dynein, axonemal, light polypeptide 4 (DNAL4), mRNA)DNAL4 PIG27 hCG_41700Q6FGD01
DNASE2B protein (Fragment)DNASE2BQ66K391
Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2))DOK2O604961
Docking protein 4 (Downstream of tyrosine kinase 4) (Insulin receptor substrate 5) (IRS-5) (IRS5)DOK4Q8TEW61
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