EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Matrix extracellular phosphoglycoprotein (Osteoblast/osteocyte factor 45) (OF45)MEPEQ9NQ761
Matrix metallopeptidase 11 (Stromelysin 3), isoform CRA_b (cDNA PSEC0140 fis, clone PLACE1005783, highly similar to STROMELYSIN-3 (EC 3.4.24.-))MMP11 hCG_41094B3KQS81
Matrix metalloproteinase-14 (MMP-14) (EC 3.4.24.80) (MMP-X1) (Membrane-type matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1) (Membrane-type-1 matrix metalloproteinase) (MT1-MMP) (MT1MMP)MMP14P502811
Matrix metalloproteinase-20 (MMP-20) (EC 3.4.24.-) (Enamel metalloproteinase) (Enamelysin)MMP20O608821
Matrix metalloproteinase-21 (MMP-21) (EC 3.4.24.-)MMP21Q8N1191
Matrix metalloproteinase-26 (MMP-26) (EC 3.4.24.-) (Endometase) (Matrilysin-2)MMP26Q9NRE11
Matrix-remodeling-associated protein 5 (Adhesion protein with leucine-rich repeats and immunoglobulin domains related to perlecan) (Adlican)MXRA5Q9NR991
MCM domain-containing protein 2MCMDC2 C8orf45Q4G0Z91
MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae), isoform CRA_a (cDNA, FLJ92902, Homo sapiens MCM5 minichromosome maintenance deficient 5, celldivision cycle 46 (S. cerevisiae) (MCM5), mRNA)MCM5 hCG_41525B1AHB01
Mdm2-binding protein (hMTBP)MTBPQ96DY71
Mediator of DNA damage checkpoint 1 variant 1 (Fragment)MDC1A1Z5I91
Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1)MDC1 KIAA0170 NFBD1Q146761
Mediator of RNA polymerase II transcription subunit 19 (Lung cancer metastasis-related protein 1) (Mediator complex subunit 19)MED19 LCMR1A0JLT21
Mediator of RNA polymerase II transcription subunit 23 (Activator-recruited cofactor 130 kDa component) (ARC130) (Cofactor required for Sp1 transcriptional activation subunit 3) (CRSP complex subunit 3) (Mediator complex subunit 23) (Protein sur-2 homolog) (hSur-2) (Transcriptional coactivator CRSP130) (Vitamin D3 receptor-interacting protein complex 130 kDa component) (DRIP130)MED23 ARC130 CRSP3 DRIP130 KIAA1216 SUR2Q9ULK41
Mediator of RNA polymerase II transcription subunit 28 (Endothelial-derived protein 1) (Mediator complex subunit 28) (Merlin and Grb2-interacting cytoskeletal protein) (Magicin) (Tumor angiogenesis marker EG-1)MED28 EG1 FKSG20Q9H2041
MEI1 proteinMEI1Q4G0I11
Meiosis-specific with OB domain-containing proteinMEIOB C16orf73Q8N6351
Meiotic recombination protein REC8 homolog (Cohesin Rec8p)REC8 REC8L1O950721
Meiotic recombination protein SPO11 (Cancer/testis antigen 35) (CT35)SPO11Q9Y5K11
Melanocortin receptor 3 (MC3-R)MC3RP419681
Melanocyte-stimulating hormone receptor (MSH-R) (Melanocortin receptor 1) (MC1-R)MC1R MSHRQ017261
Melanoma antigen family E, 1 (cDNA FLJ77131, highly similar to Homo sapiens melanoma antigen family E, 1 (MAGEE1), mRNA)MAGEE1 hCG_1647013 RP4-596C3.1-001Q5JXC71
Melanoma inhibitory activity protein 2MIA2Q96PC51
Melanoma-associated antigen 2 (Cancer/testis antigen 1.2) (CT1.2) (MAGE-2 antigen)MAGEA2 MAGE2 MAGEA2A; MAGEA2B MAGE2 MAGEA2P433561
Melanoma-associated antigen 5 (Cancer/testis antigen 1.5) (CT1.5) (MAGE-5 antigen)MAGEA5 MAGE5P433591
Melanoma-associated antigen 8 (Cancer/testis antigen 1.8) (CT1.8) (MAGE-8 antigen)MAGEA8 MAGE8P433611
Melanoma-associated antigen C1 (Cancer/testis antigen 7.1) (CT7.1) (MAGE-C1 antigen)MAGEC1O607321
Melanoma-associated antigen F1 (MAGE-F1 antigen)MAGEF1Q9HAY21
Melanoma-associated antigen G1 (Hepatocellular carcinoma-associated protein 4) (MAGE-G1 antigen) (Necdin-like protein 2)NDNL2 HCA4 MAGEG1Q96MG71
Melastatin 2 (Fragment)MLSN2Q9H2001
Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor)MTNR1BP492861
Melatonin-related receptor (G protein-coupled receptor 50) (H9)GPR50Q135851
Membrane progestin receptor gamma (mPR gamma) (Progestin and adipoQ receptor family member 5) (Progestin and adipoQ receptor family member V)PAQR5 MPRGQ9NXK61
Membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2), isoform CRA_bMPP2 hCG_30288D3DX481
Membrane-associated phospholipase A1 beta splice variant (Fragment)LOC375108Q5D1Q21
Membrane-associated transporter protein (Melanoma antigen AIM1) (Protein AIM-1) (Solute carrier family 45 member 2)SLC45A2 AIM1 MATPQ9UMX91
Membrane-bound transcription factor site-2 protease (EC 3.4.24.85) (Endopeptidase S2P) (Sterol regulatory element-binding proteins intramembrane protease) (SREBPs intramembrane protease)MBTPS2 S2PO434621
Membrane-spanning 4-domains subfamily A member 10 (CD20 antigen-like 7)MS4A10 CD20L7 MS4A9Q96PG21
Membrane-spanning 4-domains subfamily A member 12MS4A12Q9NXJ01
Membrane-spanning 4-domains subfamily A member 14 (Testis development protein NYD-SP21)MS4A14 MS4A13 MS4A16Q96JA41
Menin (Fragment)MEN1Q9GZQ51
Mesenteric estrogen-dependent adipogenesis protein (Activated in W/Wv mouse stomach 3 homolog) (hAWMS3) (Mesenteric estrogen-dependent adipose 4) (MEDA-4)MEDAG AWMS3 C13orf33 MEDA4Q5VYS41
Mesothelin (CAK1 antigen) (Pre-pro-megakaryocyte-potentiating factor) [Cleaved into: Megakaryocyte-potentiating factor (MPF); Mesothelin, cleaved form]MSLN MPFQ134211
Mesotrypsinogen (Protease, serine, 3) (Protease, serine, 3 (Mesotrypsin), isoform CRA_b)PRSS3 mesotrypsinogen hCG_2033679Q6ISJ41
Metabotropic glutamate receptor 3 (mGluR3)GRM3 GPRC1C MGLUR3Q148321
Metabotropic glutamate receptor 6 (mGluR6)GRM6 GPRC1F MGLUR6O153031
Metabotropic glutamate receptor 7 (mGluR7)GRM7 GPRC1G MGLUR7Q148311
Metabotropic glutamate receptor 8 (mGluR8)GRM8 GPRC1H MGLUR8O002221
Metal transporter CNNM4 (Ancient conserved domain-containing protein 4) (Cyclin-M4)CNNM4 ACDP4 KIAA1592Q6P4Q71
Metallo-beta-lactamase domain-containing protein 1 (EC 3.-.-.-)MBLAC1A4D2B01
Metallo-beta-lactamase domain-containing protein 2 (EC 3.-.-.-)MBLAC2Q68D911
Metalloproteinase inhibitor 4 (Tissue inhibitor of metalloproteinases 4) (TIMP-4)TIMP4Q997271
Metalloreductase STEAP4 (EC 1.16.1.-) (Six-transmembrane epithelial antigen of prostate 4) (SixTransMembrane protein of prostate 2) (Tumor necrosis factor, alpha-induced protein 9)STEAP4 STAMP2 TNFAIP9Q687X51
Metastasis-associated protein MTA3MTA3 KIAA1266Q9BTC81
Methylcytosine dioxygenase TET2 (EC 1.14.11.n2)TET2 KIAA1546 Nbla00191Q6N0211
Methylcytosine dioxygenase TET3 (EC 1.14.11.n2)TET3 KIAA0401O431511
Methylmalonic aciduria type A protein, mitochondrial (EC 3.6.-.-)MMAAQ8IVH41
Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein) (hAPIP)APIP CGI-29Q96GX91
Methyltransferase-like protein 2A (EC 2.1.1.-)METTL2A METTL2 HSPC266Q96IZ61
Methyltransferase-like protein 6 (EC 2.1.1.-)METTL6Q8TCB71
Mevalonate kinase (Mevalonate kinase (Mevalonic aciduria), isoform CRA_c) (Mevalonate kinase 1) (cDNA, FLJ96772, Homo sapiens mevalonate kinase (mevalonic aciduria) (MVK), mRNA)MVK hCG_40321B2RDU61
MHC class I polypeptide-related sequence A (MIC-A)MICA PERB11.1Q299831
MicrocephalinMCPH1Q8NEM01
Microfibril-associated glycoprotein 3MFAP3P550821
Microfibrillar-associated protein 3-like (Testis development protein NYD-SP9)MFAP3L KIAA0626 HSD-39 HSD39O751211
Microsomal triglyceride transfer protein large subunitMTTP MTPP551571
Microtubule-associated protein 2 (MAP-2)MAP2P111371
Microtubule-associated proteins 1A/1B light chain 3 beta 2 (Microtubule-associated proteins 1A/1B light chain 3B-like)MAP1LC3B2A6NCE71
Microtubule-associated proteins 1A/1B light chain 3C (Autophagy-related protein LC3 C) (Autophagy-related ubiquitin-like modifier LC3 C) (MAP1 light chain 3-like protein 3) (MAP1A/MAP1B light chain 3 C) (MAP1A/MAP1B LC3 C) (Microtubule-associated protein 1 light chain 3 gamma)MAP1LC3CQ9BXW41
Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1)MAST4 KIAA0303O150211
MIF4G domain-containing protein (SLBP-interacting protein 1) (hSLIP1)MIF4GD SLIP1A9UHW61
Mineralocorticoid receptor (MR) (Nuclear receptor subfamily 3 group C member 2)NR3C2 MCR MLRP082351
Mini-chromosome maintenance complex-binding protein (MCM-BP) (MCM-binding protein)MCMBP C10orf119Q9BTE31
Minor histocompatibility protein HA-1 [Cleaved into: Minor histocompatibility antigen HA-1 (mHag HA-1)]HMHA1 KIAA0223Q926191
MIR-10MIR cl-10A2IXV51
Mitochondrial 10-formyltetrahydrofolate dehydrogenase (Mitochondrial 10-FTHFDH) (mtFDH) (EC 1.5.1.6) (Aldehyde dehydrogenase family 1 member L2)ALDH1L2Q3SY691
Mitochondrial dicarboxylate carrier (Solute carrier family 25 member 10)SLC25A10 DICQ9UBX31
Mitochondrial DNA polymerase subunit gamma-2 (Polymerase (DNA directed), gamma 2, accessory subunit)POLG2 hCG_28169E5KS151
Mitochondrial endonuclease G0E5KNL51
Mitochondrial import inner membrane translocase subunit Tim13TIMM13 TIM13B TIMM13A TIMM13BQ9Y5L41
Mitochondrial inner membrane protease subunit 1 (EC 3.4.21.-) (IMP1-like protein)IMMP1LQ96LU51
Mitochondrial ornithine transporter 2 (Solute carrier family 25 member 2)SLC25A2 ORNT2Q9BXI21
Mitochondrial ribosomal protein L32 (Mitochondrial ribosomal protein L32, isoform CRA_d) (cDNA, FLJ93927, Homo sapiens mitochondrial ribosomal protein L32 (MRPL32), nucleargene encoding mitochondrial protein, mRNA)MRPL32 hCG_19886 tcag7.484A4D1V41
Mitochondrial tRNA-specific 2-thiouridylase 1 (EC 2.8.1.-) (MTO2 homolog)TRMU MTU1 TRMT1O756481
Mitoferrin-1 (Mitochondrial iron transporter 1) (Mitochondrial solute carrier protein) (Solute carrier family 25 member 37)SLC25A37 MFRN MSCP HT015Q9NYZ21
Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (Stress-activated protein kinase 2b) (SAPK2b) (p38-2)MAPK11 PRKM11 SAPK2 SAPK2BQ157591
Mitogen-activated protein kinase 12 (MAP kinase 12) (MAPK 12) (EC 2.7.11.24) (Extracellular signal-regulated kinase 6) (ERK-6) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) (Stress-activated protein kinase 3)MAPK12 ERK6 SAPK3P537781
Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF-kappa-beta-inducing kinase) (HsNIK) (Serine/threonine-protein kinase NIK)MAP3K14 NIKQ995581
Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 3) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15)MAP3K15 ASK3Q6ZN161
Mitogen-activated protein kinase kinase kinase 5 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 1) (ASK-1) (MAPK/ERK kinase kinase 5) (MEK kinase 5) (MEKK 5)MAP3K5 ASK1 MAPKKK5 MEKK5Q996831
Mitogen-activated protein kinase kinase kinase MLK4 (EC 2.7.11.25) (Mixed lineage kinase 4)MLK4 KIAA1804Q5TCX81
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1)BUB1B BUBR1 MAD3L SSK1O605661
MKL/myocardin-like protein 1 (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein) (Myocardin-related transcription factor A) (MRTF-A)MKL1 KIAA1438 MALQ969V61
MMP17 proteinMMP17Q8IWC31
MOB kinase activator 1B (Mob1 homolog 1A) (Mob1A) (Mob1B) (Mps one binder kinase activator-like 1A)MOB1B MOB4A MOBKL1AQ7L9L41
Monoacylglycerol lipase ABHD6 (EC 3.1.1.23) (2-arachidonoylglycerol hydrolase) (Abhydrolase domain-containing protein 6)ABHD6Q9BV231
Monocarboxylate transporter 1 (MCT 1) (Solute carrier family 16 member 1)SLC16A1 MCT1P539851
Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1)SLC16A10 MCT10 TAT1Q8TF711
Monocarboxylate transporter 12SLC16A12E9PSF91
Monocarboxylate transporter 13 (MCT 13) (Solute carrier family 16 member 13)SLC16A13 MCT13Q7RTY01
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