EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
NEDD8 ultimate buster 1 (NEDD8 ultimate buster-1, isoform CRA_d)NUB1 NYREN18 hCG_19587H3BM141
Nef-associated factor 1 isoform 1 (Nef-associated factor 1 isoform 3) (TNFAIP3 interacting protein 1, isoform CRA_a)NAF1 TNIP1 hCG_39151A4F1W81
Negative elongation factor C/D (TH1-like (Drosophila), isoform CRA_b)TH1L NELFCD hCG_28547H0UI801
NEK9 protein (Fragment)NEK9Q6PKF21
Nephrin (Renal glomerulus-specific cell adhesion receptor)NPHS1 NPHNO605001
Nephrocystin-1 (Juvenile nephronophthisis 1 protein)NPHP1 NPH1O152591
Nephrocystin-4 (Nephroretinin)NPHP4 KIAA0673O751611
Nephronectin (Preosteoblast EGF-like repeat protein with MAM domain) (Protein EGFL6-like)NPNT EGFL6L POEM UNQ295/PRO334Q6UXI91
Nescient helix loop helix 1 (cDNA, FLJ94293, Homo sapiens nescient helix loop helix 1 (NHLH1), mRNA)NHLH1 hCG_20859Q5T2031
Nesprin-1 (Enaptin) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)SYNE1 C6orf98 KIAA0796 KIAA1262 KIAA1756 MYNE1Q8NF911
Netrin receptor UNC5A (Protein unc-5 homolog 1) (Protein unc-5 homolog A)UNC5A KIAA1976 UNC5H1Q6ZN441
Netrin-3 (Netrin-2-like protein)NTN3 NTN2LO006341
NEU1 protein (Sialidase 1 (Lysosomal sialidase), isoform CRA_a) (cDNA, FLJ93471, Homo sapiens sialidase 1 (lysosomal sialidase) (NEU1), mRNA)NEU1 hCG_43692Q5JQI01
Neural cell adhesion molecule 2 (N-CAM-2) (NCAM-2)NCAM2 NCAM21O153941
Neuralized-like protein 1A (h-neu) (h-neuralized 1) (EC 6.3.2.-) (RING finger protein 67)NEURL NEURL1 NEURL1A RNF67O760501
Neurensin-1 (Neuro-p24) (Vesicular membrane protein of 24 kDa) (Vesicular membrane protein p24)NRSN1 VMPQ8IZ571
Neurexin-1 (Neurexin I-alpha) (Neurexin-1-alpha)NRXN1 KIAA0578Q9ULB11
Neurexin-3-beta (Neurexin III-beta) [Cleaved into: Neurexin-3-beta, soluble form; Neurexin-3-beta, C-terminal fragment (NRXN3-CTF)]NRXN3 KIAA0743Q9HDB51
Neurexophilin-2NXPH2 NPH2O951561
Neuritin-like proteinNRN1L UNQ2446/PRO5725Q496H81
Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein)NBEAL1 ALS2CR16 ALS2CR17Q6ZS301
Neurobeachin-like protein 2NBEAL2 KIAA0540 UNQ253/PRO290Q6ZNJ11
Neuroblastoma breakpoint family member 1NBPF1 KIAA1693Q3BBV01
Neuroblastoma breakpoint family member 20NBPF20Q3BBV11
Neuroblastoma breakpoint family member 6NBPF6E9PDL31
Neuroblastoma-amplified sequence (Fragment)NBASG1UI261
Neuroblastoma-amplified sequence (Neuroblastoma-amplified gene protein)NBAS NAGA2RRP11
Neurocalcin delta, isoform CRA_a (cDNA FLJ30511 fis, clone BRAWH2000636, highly similar to NEUROCALCIN DELTA) (cDNA FLJ39196 fis, clone OCBBF2005066, highly similar to NEUROCALCIN DELTA) (cDNA, FLJ95342, highly similar to Homo sapiens neurocalcin delta (NCALD), mRNA)NCALD hCG_16241B2RB701
NEUROD4 protein0Q8IW561
Neuroendocrine convertase 1 (NEC 1) (EC 3.4.21.93) (Prohormone convertase 1) (Proprotein convertase 1) (PC1)PCSK1 NEC1P291201
Neuroendocrine convertase 2 (NEC 2) (EC 3.4.21.94) (KEX2-like endoprotease 2) (Prohormone convertase 2) (Proprotein convertase 2) (PC2)PCSK2 NEC2P165191
Neuroepithelial cell transforming gene 1, isoform CRA_b (cDNA FLJ50843, highly similar to Neuroepithelial cell-transforming gene 1 protein)NET1 hCG_19072Q5SQI51
NeurofascinNFASC KIAA0756O948561
Neurofilament light polypeptide (NF-L) (68 kDa neurofilament protein) (Neurofilament triplet L protein)NEFL NF68 NFLP071961
Neurogenic differentiation factor 1 (NeuroD) (NeuroD1) (Class A basic helix-loop-helix protein 3) (bHLHa3)NEUROD1 BHLHA3 NEURODQ135621
Neurogenic differentiation factor 2 (NeuroD2) (Class A basic helix-loop-helix protein 1) (bHLHa1) (NeuroD-related factor) (NDRF)NEUROD2 BHLHA1 NDRFQ157841
Neurogenic locus notch homolog protein 4 (Notch 4) (hNotch4) [Cleaved into: Notch 4 extracellular truncation; Notch 4 intracellular domain]NOTCH4 INT3Q994661
Neurogenin-2 (NGN-2) (Class A basic helix-loop-helix protein 8) (bHLHa8) (Protein atonal homolog 4)NEUROG2 ATOH4 BHLHA8 NGN2Q9H2A31
Neuroligin-3 (Gliotactin homolog)NLGN3 KIAA1480 NL3Q9NZ941
Neuroligin-4, Y-linked (Neuroligin Y)NLGN4Y KIAA0951Q8NFZ31
Neurolysin, mitochondrial (EC 3.4.24.16) (Angiotensin-binding protein) (Microsomal endopeptidase) (MEP) (Mitochondrial oligopeptidase M) (Neurotensin endopeptidase)NLN AGTBP KIAA1226Q9BYT81
Neuromedin-K receptor (NKR) (NK-3 receptor) (NK-3R) (Neurokinin B receptor) (Tachykinin receptor 3)TACR3 NK3R TAC3RP293711
Neuron navigator 1 (Pore membrane and/or filament-interacting-like protein 3) (Steerin-1) (Unc-53 homolog 1) (unc53H1)NAV1 KIAA1151 KIAA1213 POMFIL3 STEERIN1Q8NEY11
Neuron-specific protein family member 2 (Protein p19) (Hmp19)NSG2Q9Y3281
Neuronal acetylcholine receptor subunit alpha-10 (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10)CHRNA10 NACHRA10Q9GZZ61
Neuronal acetylcholine receptor subunit alpha-3CHRNA3 NACHRA3P322971
Neuronal acetylcholine receptor subunit alpha-5CHRNA5 NACHRA5P305321
Neuronal acetylcholine receptor subunit alpha-9 (Nicotinic acetylcholine receptor subunit alpha-9) (NACHR alpha-9)CHRNA9 NACHRA9Q9UGM11
Neuronal acetylcholine receptor subunit beta-3CHRNB3Q059011
Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (Class E basic helix-loop-helix protein 79) (bHLHe79) (HLH-PAS transcription factor NXF) (PAS domain-containing protein 10)NPAS4 BHLHE79 NXF PASD10Q8IUM71
Neuronal pentraxin receptorNPTXRO955021
Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor)NPFFR2 GPR74 NPFF2 NPGPRQ9Y5X51
Neuropeptide Y (cDNA, FLJ92442, Homo sapiens neuropeptide Y (NPY), mRNA)NPY hCG_37313 tcag7.159A4D1581
Neuropilin and tolloid-like protein 1 (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1)NETO1 BTCL1Q8TDF51
Neuroserpin (Peptidase inhibitor 12) (PI-12) (Serpin I1)SERPINI1 PI12Q995741
Neurotensin receptor type 1 (NT-R-1) (NTR1) (High-affinity levocabastine-insensitive neurotensin receptor) (NTRH)NTSR1 NTRRP309891
Neurotrophic tyrosine kinase, receptor, type 2, isoform CRA_a (cDNA FLJ76753, highly similar to Homo sapiens neurotrophic tyrosine kinase, receptor, type 2 (NTRK2), transcript variant b, mRNA)NTRK2 hCG_1985371Q5VWE51
Neurotrophin-4 (NT-4) (Neurotrophin-5) (NT-5) (Neutrophic factor 4)NTF4 NTF5P341301
Neutrophil cytosol factor 2 (NCF-2) (67 kDa neutrophil oxidase factor) (NADPH oxidase activator 2) (Neutrophil NADPH oxidase factor 2) (p67-phox)NCF2 NOXA2 P67PHOXP198781
NF-kappa-B inhibitor delta (I-kappa-B-delta) (IkB-delta) (IkappaBdelta) (IkappaBNS) (T-cell activation NFKB-like protein) (TA-NFKBH)NFKBID IKBNSQ8NI381
NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkB-E) (IkB-epsilon) (IkappaBepsilon)NFKBIE IKBEO002211
NF-kappa-B-activating proteinNKAPQ8N5F71
NF-kappaB repressing factor (NF-kappaB repressing factor, isoform CRA_b)NRF NKRF hCG_23185A3F7691
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial (HIRA-interacting protein 5)NFU1 HIRIP5 CGI-33Q9UMS01
NFX1 protein (Fragment)NFX1A0JLR21
NFX1-type zinc finger-containing protein 1ZNFX1 KIAA1404Q9P2E31
NHL-repeat-containing protein 4NHLRC4P0CG211
NicastrinNCSTN KIAA0253 UNQ1874/PRO4317Q925421
Nicotinamide mononucleotide adenylyltransferase 1 (NMN adenylyltransferase 1) (EC 2.7.7.1) (Nicotinate-nucleotide adenylyltransferase 1) (NaMN adenylyltransferase 1) (EC 2.7.7.18)NMNAT1 NMNATQ9HAN91
Ninein isoform 6NINQ5XUU01
Ninjurin-2 (Nerve injury-induced protein 2)NINJ2Q9NZG71
Nitric oxide synthase (EC 1.14.13.39)0B4DG681
Nitric oxide synthase, brain (EC 1.14.13.39) (Constitutive NOS) (NC-NOS) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Peptidyl-cysteine S-nitrosylase NOS1) (bNOS)NOS1P294751
NK1 transcription factor-related protein 2 (Homeobox protein SAX-1) (NKX-1.1)NKX1-2 C10orf121 NKX1.1Q9UD571
NKAP-like proteinNKAPL C6orf194Q5M9Q11
NKG2-C type II integral membrane protein (CD159 antigen-like family member C) (NK cell receptor C) (NKG2-C-activating NK receptor) (CD antigen CD159c)KLRC2 NKG2CP267171
NLR family CARD domain-containing protein 4 (CARD, LRR, and NACHT-containing protein) (Clan protein) (Caspase recruitment domain-containing protein 12) (Ice protease-activating factor) (Ipaf)NLRC4 CARD12 CLAN CLAN1 IPAF UNQ6189/PRO20215Q9NPP41
NLRC3 (NOD3 protein, isoform CRA_c)NLRC3 NOD3 hCG_2036791C3VPR71
NMDA receptor synaptonuclear signaling and neuronal migration factor (Nasal embryonic luteinizing hormone-releasing hormone factor) (Nasal embryonic LHRH factor)NSMF NELFQ6X4W11
Nociceptin receptor (Kappa-type 3 opioid receptor) (KOR-3) (Orphanin FQ receptor)OPRL1 OOR ORL1P411461
Nocturnin (CCR4 protein homolog)CCRN4L CCR4 NOCQ9UK391
Nodal modulator 1 (pM5 protein)NOMO1 PM5Q151551
Nogo-B receptor (NgBR) (Nuclear undecaprenyl pyrophosphate synthase 1 homolog)NUS1 C6orf68 NGBRQ96E221
Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)TNK1Q134701
Non-secretory ribonuclease (EC 3.1.27.5) (Eosinophil-derived neurotoxin) (RNase UpI-2) (Ribonuclease 2) (RNase 2) (Ribonuclease US)RNASE2 EDN RNS2P101531
Noncompact myelin-associated protein (Myelin protein of 11 kDa) (MP11)NCMAP C1orf130Q5T1S81
Norrin (Norrie disease protein) (X-linked exudative vitreoretinopathy 2 protein)NDP EVR2Q006041
NRF1 protein (Nuclear factor erythroid 2-related factor 1) (Nuclear respiratory factor 1) (Nuclear respiratory factor 1, isoform CRA_b)NRF1 hCG_1811093Q96AN21
NTPase KAP family P-loop domain-containing protein 1NKPD1J3KNK31
Nuclear distribution protein nudE homolog 1 (NudE)NDE1 NUDEQ9NXR11
Nuclear factor of activated T-cells (Tonicity-responsive enhancer binding protein)NFAT5/TonEBP NFAT5Q7LA651
Nuclear factor of activated T-cells, cytoplasmic 1 (NF-ATc1) (NFATc1) (NFAT transcription complex cytosolic component) (NF-ATc) (NFATc)NFATC1 NFAT2 NFATCO956441
Nuclear factor of activated T-cells, cytoplasmic 2 (NF-ATc2) (NFATc2) (NFAT pre-existing subunit) (NF-ATp) (T-cell transcription factor NFAT1)NFATC2 NFAT1 NFATPQ134691
Nuclear fragile X mental retardation protein interacting protein 2 (Nuclear fragile X mental retardation protein interacting protein 2, isoform CRA_a) (cDNA FLJ75095, highly similar to Homo sapiens 82-kD FMRP Interacting Protein (182-FIP), mRNA)NUFIP2 hCG_29087A1L3A71
Nuclear pore complex protein Nup107 (107 kDa nucleoporin) (Nucleoporin Nup107)NUP107P577401
Nuclear pore-associated protein 1NPAP1 C15orf2Q9NZP61
Nuclear protein MDM1MDM1Q8TC051
Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA)NCOA5 KIAA1637Q9HCD51
Nuclear receptor interacting protein 2 (cDNA FLJ40744 fis, clone TRACH2000045, highly similar to Homo sapiens nuclear receptor interacting protein 2 (NRIP2), mRNA)NRIP2 hCG_27039A2RRE31
Nuclear receptor subfamily 0 group B member 2 (Orphan nuclear receptor SHP) (Small heterodimer partner)NR0B2 SHPQ154661
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