EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
PCNA-interacting partner (PARI) (PARP-1 binding protein) (PARP1-binding protein) (PARPBP)PARPBP C12orf48 PARIQ9NWS11
PDC protein (Fragment)PDCQ52LP81
PDE6D protein (Phosphodiesterase 6D, cGMP-specific, rod, delta, isoform CRA_b) (Putative uncharacterized protein tmp_locus_12)PDE6D tmp_locus_12 hCG_32951Q6IB241
PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha-actinin-2-associated LIM protein)PDLIM3 ALPQ53GG51
PDZ domain-containing protein 11 (ATPase-interacting PDZ protein) (Plasma membrane calcium ATPase-interacting single-PDZ protein) (PMCA-interacting single-PDZ protein)PDZD11 AIPP1 PDZK11 PISP HSPC227 UNQ6486/PRO21335Q5EBL81
PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR-104)PDZD8 PDZK8Q8NEN91
PDZ domain-containing protein MAGIXMAGIXQ9H6Y51
Pecanex-like protein 4PCNXL4B6ZDM21
Pellino (Pellino homolog 1 (Drosophila), isoform CRA_a) (Putative uncharacterized protein PELI1) (cDNA, FLJ92790, Homo sapiens pellino homolog 1 (Drosophila) (PELI1), mRNA)PELI1 hCG_22381Q53T261
Pentatricopeptide repeat domain 1 (cDNA FLJ76276, highly similar to Homo sapiens pentatricopeptide repeat domain 1 (PTCD1), mRNA)PTCD1 hCG_2023422 tcag7.1151A4D2731
Pentatricopeptide repeat domain-containing protein 3, mitochondrial (28S ribosomal protein S39, mitochondrial) (MRP-S39) (Transformation-related gene 15 protein) (TRG-15)PTCD3 MRPS39 TRG15Q96EY71
Pepsin A-4 (EC 3.4.23.1) (Pepsinogen-4)PGA4P0DJD71
Pepsin A-5 (EC 3.4.23.1) (Pepsinogen-5)PGA5P0DJD91
Peptide chain release factor 1, mitochondrial (MRF-1) (MtRF-1)MTRF1O755701
Peptidyl-prolyl cis-trans isomeraseFKBP2 hCG_21364Q53XJ51
Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (Fragment)PPIH hCG_21746Q6FH361
Peptidyl-prolyl cis-trans isomerase FKBP9 (PPIase FKBP9) (EC 5.2.1.8) (63 kDa FK506-binding protein) (63 kDa FKBP) (FKBP-63) (FK506-binding protein 9) (FKBP-9) (Rotamase)FKBP9 FKBP60 FKBP63O953021
Peptidyl-prolyl cis-trans isomerase-like 4 (PPIase) (EC 5.2.1.8) (Cyclophilin-like protein PPIL4) (Rotamase PPIL4)PPIL4Q8WUA21
Peptidyl-prolyl cis-trans isomerase-like 6 (PPIase) (EC 5.2.1.8) (Cyclophilin-like protein PPIL6) (Rotamase PPIL6)PPIL6Q8IXY81
PerilipinADFP hCG_28271Q6FHZ71
Periodic tryptophan protein 2 homologPWP2 PWP2HQ152691
Peroxidasin-like protein (EC 1.11.1.7) (Cardiac peroxidase) (Vascular peroxidase 2) (polysomal ribonuclease 1) (PRM1)PXDNL VPO2A1KZ921
Peroxisomal acyl-coenzyme A oxidase 3 (EC 1.3.3.6) (Branched-chain acyl-CoA oxidase) (BRCACox) (Pristanoyl-CoA oxidase)ACOX3 BRCOX PRCOXO152541
Peroxisomal bifunctional enzyme (PBE) (PBFE) [Includes: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase (EC 4.2.1.17) (EC 5.3.3.8); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)]EHHADH ECHDQ084261
Peroxisomal biogenesis factor 11A (cDNA FLJ10553 fis, clone NT2RP2002325, highly similar to Peroxisomal membrane protein 11A) (cDNA, FLJ93834, Homo sapiens peroxisomal biogenesis factor 11A (PEX11A), mRNA)PEX11A hCG_26632B2R8C61
Peroxisomal membrane protein 11A (HsPEX11p) (28 kDa peroxisomal integral membrane protein) (PMP28) (Peroxin-11A) (Peroxisomal biogenesis factor 11A) (Protein PEX11 homolog alpha) (PEX11-alpha)PEX11A PEX11O751921
Peroxisomal membrane protein 11C (Peroxin-11C) (Peroxisomal biogenesis factor 11C) (Protein PEX11 homolog gamma) (PEX11-gamma)PEX11G PEX11CQ96HA91
Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12)NUDT12Q9BQG21
Peroxisomal sarcosine oxidase (PSO) (EC 1.5.3.1) (EC 1.5.3.7) (L-pipecolate oxidase) (L-pipecolic acid oxidase)PIPOX LPIPOX PSOQ9P0Z91
Peroxisomal testis-specific protein 1 (Small testis-specific peroxisomal protein)PXT1 STEPPQ8NFP01
Peroxisomal trans-2-enoyl-CoA reductase (TERP) (EC 1.3.1.38) (2,4-dienoyl-CoA reductase-related protein) (DCR-RP) (HPDHase) (pVI-ARL)PECR PRO1004Q9BY491
PGAP2-interacting protein (Cell wall biogenesis protein 43 C-terminal homolog)CWH43 PGAP2IPQ9H7201
PH and SEC7 domain-containing protein 1 (Exchange factor for ARF6) (Pleckstrin homology and SEC7 domain-containing protein 1)PSD EFA6 KIAA2011 PSD1 TYLA5PKW41
PH and SEC7 domain-containing protein 2 (Pleckstrin homology and SEC7 domain-containing protein 2)PSD2Q9BQI71
PH domain leucine-rich repeat-containing protein phosphatase 2 (EC 3.1.3.16) (PH domain leucine-rich repeat-containing protein phosphatase-like) (PHLPP-like)PHLPP2 KIAA0931 PHLPPLQ6ZVD81
Phakinin (49 kDa cytoskeletal protein) (Beaded filament structural protein 2) (Lens fiber cell beaded filament protein CP 47) (CP47) (Lens fiber cell beaded filament protein CP 49) (CP49) (Lens intermediate filament-like light) (LIFL-L)BFSP2Q135151
PHD finger protein 10 (BRG1-associated factor 45a) (BAF45a) (XAP135)PHF10 BAF45AQ8WUB81
PHD finger protein 6 (PHD-like zinc finger protein)PHF6 KIAA1823Q8IWS01
Phenazine biosynthesis-like domain-containing protein (EC 5.1.-.-) (MAWD-binding protein) (MAWDBP) (Unknown protein 32 from 2D-page of liver tissue)PBLD MAWBPP300391
PHLDB3 protein (Fragment)PHLDB3Q96HZ01
Phosducin-like protein 2PDCL2Q8N4E41
Phosphate-regulating neutral endopeptidase (EC 3.4.24.-) (Metalloendopeptidase homolog PEX) (Vitamin D-resistant hypophosphatemic rickets protein) (X-linked hypophosphatemia protein) (HYP)PHEX PEXP785621
Phosphatidate phosphatase PPAPDC1B (EC 3.1.3.4) (Phosphatidic acid phosphatase type 2 domain-containing protein 1B)PPAPDC1B DPPL1 HTPAPQ8NEB51
Phosphatidylethanolamine-binding protein 4 (PEBP-4) (hPEBP4) (Protein cousin-of-RKIP 1)PEBP4 CORK1 UNQ1933/PRO4408Q96S961
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 (EC 3.1.3.27) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase) (Protein-tyrosine phosphatase mitochondrial 1) (EC 3.1.3.16) (EC 3.1.3.48)PTPMT1 MOSP PLIP PNAS-129Q8WUK01
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (Lipid phosphatase TPIP) (TPTE and PTEN homologous inositol lipid phosphatase)TPTE2 TPIPQ6XPS31
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (P-Rex1) (PtdIns(3,4,5)-dependent Rac exchanger 1)PREX1 KIAA1415Q8TCU61
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) (PI3K-gamma) (PI3Kgamma) (PtdIns-3-kinase subunit gamma) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma) (PtdIns-3-kinase subunit p110-gamma) (p110gamma) (Phosphoinositide-3-kinase catalytic gamma polypeptide) (Serine/threonine protein kinase PIK3CG) (EC 2.7.11.1) (p120-PI3K)PIK3CGP487361
Phosphatidylinositol 4-phosphate 5-kinase type-1 beta (PIP5K1-beta) (PtdIns(4)P-5-kinase 1 beta) (EC 2.7.1.68) (Phosphatidylinositol 4-phosphate 5-kinase type I beta) (PIP5KIbeta) (Protein STM-7) (Type I phosphatidylinositol 4-phosphate 5-kinase beta)PIP5K1B STM7O149861
Phosphoglycerate kinase 2 (EC 2.7.2.3) (Phosphoglycerate kinase, testis specific)PGK2 PGKBP072051
Phosphoglycerate mutase 2 (EC 3.1.3.13) (EC 5.4.2.11) (EC 5.4.2.4) (BPG-dependent PGAM 2) (Muscle-specific phosphoglycerate mutase) (Phosphoglycerate mutase isozyme M) (PGAM-M)PGAM2 PGAMMP152591
Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein)PIK3R4Q995701
Phosphoinositide-3-kinase, regulatory subunit 3 (Gamma)PIK3R3Q8N3811
Phosphoinositide-interacting proteinPIRTP0C8511
Phospholemman (FXYD domain-containing ion transport regulator 1)FXYD1 PLMO001681
Phospholipase A1 member A (EC 3.1.1.-) (Phosphatidylserine-specific phospholipase A1) (PS-PLA1)PLA1A NMD PSPLA1Q53H761
Phospholipase A2 (EC 3.1.1.4) (Group IB phospholipase A2) (Phosphatidylcholine 2-acylhydrolase 1B)PLA2G1B PLA2 PLA2A PPLA2P040541
Phosphoprotein enriched in astrocytes 15, isoform CRA_a (cDNA, FLJ92023, Homo sapiens phosphoprotein enriched in astrocytes 15 (PEA15),mRNA)PEA15 hCG_39732B1AKZ41
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) (EC 2.7.11.19) (Phosphorylase kinase subunit gamma-1) (Serine/threonine-protein kinase PHKG1) (EC 2.7.11.1) (EC 2.7.11.26)PHKG1 PHKGQ168161
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (Phosphorylase kinase alpha M subunit)PHKA1 PHKAP460201
Phytanoyl-CoA dioxygenase domain-containing protein 1 (EC 1.-.-.-)PHYHD1Q5SRE71
Phytanoyl-CoA hydroxylase-interacting protein (Phytanoyl-CoA hydroxylase-associated protein 1) (PAHX-AP1) (PAHXAP1)PHYHIP DYRK1AP3 KIAA0273Q925611
PI-PLC X domain-containing protein 1PLCXD1Q9NUJ71
PI-PLC X domain-containing protein 3PLCXD3Q63HM91
Pigment epithelium-derived factor (PEDF) (Cell proliferation-inducing gene 35 protein) (EPC-1) (Serpin F1)SERPINF1 PEDF PIG35P369551
PIH1 domain-containing protein 2PIH1D2Q8WWB51
PIK4CA variant protein (Fragment)PIK4CA variant proteinQ4LE691
Pituitary-specific positive transcription factor 1 (PIT-1) (Growth hormone factor 1) (GHF-1)POU1F1 GHF1 PIT1P280691
Piwi-like protein 1PIWIL1 HIWIQ96J941
Placenta-specific gene 8 protein (Protein C15)PLAC8 BM-004Q9NZF11
Placenta-specific protein 4PLAC4 C21orf115 D21S418E PP1416Q8WY501
Placental protein 13-like (Charcot-Leyden crystal protein 2) (CLC2) (Galectin-14) (Gal-14)LGALS14 PPL13Q8TCE91
Plasma alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase 2) (Alpha-L-fucosidase 2)FUCA2 PSEC0151 UNQ227/PRO260Q9BTY21
Plasma membrane calcium-transporting ATPase 1 (PMCA1) (EC 3.6.3.8) (Plasma membrane calcium ATPase isoform 1) (Plasma membrane calcium pump isoform 1)ATP2B1 PMCA1P200201
Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 3.6.3.8) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2)ATP2B2 PMCA2Q018141
Plasminogen activator inhibitor 2 (PAI-2) (Monocyte Arg-serpin) (Placental plasminogen activator inhibitor) (Serpin B2) (Urokinase inhibitor)SERPINB2 PAI2 PLANH2P051201
Platelet basic protein (PBP) (C-X-C motif chemokine 7) (Leukocyte-derived growth factor) (LDGF) (Macrophage-derived growth factor) (MDGF) (Small-inducible cytokine B7) [Cleaved into: Connective tissue-activating peptide III (CTAP-III) (LA-PF4) (Low-affinity platelet factor IV); TC-2; Connective tissue-activating peptide III(1-81) (CTAP-III(1-81)); Beta-thromboglobulin (Beta-TG); Neutrophil-activating peptide 2(74) (NAP-2(74)); Neutrophil-activating peptide 2(73) (NAP-2(73)); Neutrophil-activating peptide 2 (NAP-2); TC-1; Neutrophil-activating peptide 2(1-66) (NAP-2(1-66)); Neutrophil-activating peptide 2(1-63) (NAP-2(1-63))]PPBP CTAP3 CXCL7 SCYB7 TGB1 THBGB1P027751
Platelet factor 4 variant (C-X-C motif chemokine 4 variant) (CXCL4L1) (PF4alt) (PF4var1) [Cleaved into: Platelet factor 4 variant(4-74); Platelet factor 4 variant(5-74); Platelet factor 4 variant(6-74)]PF4V1 CXCL4V1 SCYB4V1P107201
Platelet-activating factor acetylhydrolase (PAF acetylhydrolase) (EC 3.1.1.47) (1-alkyl-2-acetylglycerophosphocholine esterase) (2-acetyl-1-alkylglycerophosphocholine esterase) (Group-VIIA phospholipase A2) (gVIIA-PLA2) (LDL-associated phospholipase A2) (LDL-PLA(2)) (PAF 2-acylhydrolase)PLA2G7 PAFAHQ130931
Platelet-activating factor receptor (PAF-R) (PAFr)PTAFR PAFRP251051
Platelet-derived growth factor receptor beta variant (Fragment)0Q59F041
PLCG1 variant protein (Fragment)PLCG1 variant proteinQ4LE431
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)PLEKHA7Q6IQ231
Pleckstrin homology domain-containing family N member 1 (PH domain-containing family N member 1)PLEKHN1Q494U11
Pleckstrin homology domain-interacting protein variant 1PHIPA7J9921
Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha)PHLDB1 KIAA0638 LL5A DLNB07Q86UU11
Pleckstrin-2PLEK2Q9NYT01
Pleiomorphic adenoma gene-like protein 1 (Fragment)PLAGL1A1YLA11
Plexin A4, B, isoform CRA_a (Plexin-A4) (Uncharacterized protein)DKFZp434G0625 PLXNA4 PLXNA4B hCG_2014152A4D1N61
Plexin domain-containing protein 1 (Tumor endothelial marker 3) (Tumor endothelial marker 7)PLXDC1 TEM3 TEM7Q8IUK51
Plexin-C1 (Virus-encoded semaphorin protein receptor) (CD antigen CD232)PLXNC1 VESPRO604861
PMP22 protein (Peripheral myelin protein 22) (cDNA FLJ77074, highly similar to Homo sapiens peripheral myelin protein 22 (PMP22), transcript variant 2, mRNA)PMP22Q6FH251
PMPCB protein (Fragment)PMPCBQ96CP51
PMS1 protein homolog 1 (DNA mismatch repair protein PMS1)PMS1 PMSL1P542771
PMVK protein (Phosphomevalonate kinase, isoform CRA_a) (cDNA, FLJ93228, Homo sapiens phosphomevalonate kinase (PMVK), mRNA) (Fragment)PMVK hCG_1739272Q6FGV91
POC1 centriolar protein homolog A (Pix2) (WD repeat-containing protein 51A)POC1A WDR51AQ8NBT01
PodocanPODN SLRR5A UNQ293/PRO332Q7Z5L71
Podocan-like protein 1 (cDNA FLJ51218, weakly similar to Mus musculus podocan (Podn), mRNA)PODNL1B7Z3M01
PodocinNPHS2Q9NP851
Poliovirus receptor-related protein 3 (CDw113) (Nectin-3) (CD antigen CD113)PVRL3 PRR3Q9NQS31
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