EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Poly (ADP-ribose) polymerase family, member 12, isoform CRA_b (Zinc finger CCCH type domain containing 1)ZC3HDC1 PARP12 hCG_1811077A4D1T01
Poly(A) polymerase gamma (PAP-gamma) (EC 2.7.7.19) (Neo-poly(A) polymerase) (Neo-PAP) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3'-adenylating enzyme)PAPOLG PAP2 PAPGQ9BWT31
Poly(A) RNA polymerase, mitochondrial (PAP) (EC 2.7.7.19) (PAP-associated domain-containing protein 1) (Polynucleotide adenylyltransferase) (Terminal uridylyltransferase 1) (TUTase 1) (mtPAP)MTPAP PAPD1Q9NVV41
Poly(A)-specific ribonuclease PARN-like domain-containing protein 1PNLDC1Q8NA581
Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143)PARGQ86W561
Polyadenylate-binding protein 5 (PABP-5) (Poly(A)-binding protein 5)PABPC5 PABP5Q96DU91
Polycomb group RING finger protein 1 (Nervous system Polycomb-1) (NSPc1) (RING finger protein 68)PCGF1 NSPC1 RNF68Q9BSM11
Polycomb group RING finger protein 5 (RING finger protein 159)PCGF5 RNF159Q86SE91
Polypeptide N-acetylgalactosaminyltransferase 10 (EC 2.4.1.41) (Polypeptide GalNAc transferase 10) (GalNAc-T10) (pp-GaNTase 10) (Protein-UDP acetylgalactosaminyltransferase 10) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10)GALNT10Q86SR11
Polypeptide N-acetylgalactosaminyltransferase 14 (EC 2.4.1.41) (Polypeptide GalNAc transferase 14) (GalNAc-T14) (pp-GaNTase 14) (Protein-UDP acetylgalactosaminyltransferase 14) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 14)GALNT14 UNQ2434/PRO4994Q96FL91
Polypeptide N-acetylgalactosaminyltransferase 4 (EC 2.4.1.41) (Polypeptide GalNAc transferase 4) (GalNAc-T4) (pp-GaNTase 4) (Protein-UDP acetylgalactosaminyltransferase 4) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4)GALNT4Q8N4A01
Polypeptide N-acetylgalactosaminyltransferase 6 (EC 2.4.1.41) (Polypeptide GalNAc transferase 6) (GalNAc-T6) (pp-GaNTase 6) (Protein-UDP acetylgalactosaminyltransferase 6) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 6)GALNT6Q8NCL41
Polypeptide N-acetylgalactosaminyltransferase 9 (EC 2.4.1.41) (Polypeptide GalNAc transferase 9) (GalNAc-T9) (pp-GaNTase 9) (Protein-UDP acetylgalactosaminyltransferase 9) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 9)GALNT9Q9HCQ51
Post-GPI attachment to proteins factor 2 (FGF receptor-activating protein 1)PGAP2 FRAG1Q9UHJ91
Post-GPI attachment to proteins factor 3 (COS16 homolog) (hCOS16) (Gene coamplified with ERBB2 protein) (PER1-like domain-containing protein 1)PGAP3 CAB2 PERLD1 UNQ546/PRO1100Q96FM11
Potassium channel regulatory protein (Potassium channel regulator) (Protein CLLD4)KCNRG CLLD4Q8N5I31
Potassium channel subfamily K member 12 (Tandem pore domain halothane-inhibited potassium channel 2) (THIK-2)KCNK12Q9HB151
Potassium channel subfamily K member 13 (Tandem pore domain halothane-inhibited potassium channel 1) (THIK-1)KCNK13Q9HB141
Potassium channel subfamily K member 17 (2P domain potassium channel Talk-2) (Acid-sensitive potassium channel protein TASK-4) (TWIK-related acid-sensitive K(+) channel 4) (TWIK-related alkaline pH-activated K(+) channel 2) (TALK-2)KCNK17 TALK2 TASK4 UNQ5816/PRO19634Q96T541
Potassium channel subfamily K member 18 (TWIK-related individual potassium channel) (TWIK-related spinal cord potassium channel)KCNK18 TRESK TRIKQ7Z4181
Potassium channel subfamily T member 1 (KCa4.1)KCNT1 KIAA1422Q5JUK31
Potassium channel subfamily T member 2 (Sequence like an intermediate conductance potassium channel subunit) (Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1)KCNT2 SLICKQ6UVM31
Potassium voltage-gated channel subfamily A member 5 (HPCN1) (Voltage-gated potassium channel HK2) (Voltage-gated potassium channel subunit Kv1.5)KCNA5P224601
Potassium voltage-gated channel subfamily A member 7 (Voltage-gated potassium channel subunit Kv1.7)KCNA7Q96RP81
Potassium voltage-gated channel subfamily E member 1-like protein (AMME syndrome candidate gene 2 protein)KCNE1L AMMECR2Q9UJ901
Potassium voltage-gated channel subfamily E member 4 (Potassium voltage-gated channel, Isk-related family, member 4) (cDNA, FLJ93702, highly similar to Homo sapiens potassium voltage-gated channel, Isk-related family, member 4 (KCNE4), mRNA)KCNE4 hCG_1643888A5H1P51
Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4)KCNG4 KCNG3Q8TDN11
Potassium voltage-gated channel subfamily H member 7 (Ether-a-go-go-related gene potassium channel 3) (ERG-3) (Eag-related protein 3) (Ether-a-go-go-related protein 3) (hERG-3) (Voltage-gated potassium channel subunit Kv11.3)KCNH7 ERG3Q9NS401
Potassium voltage-gated channel subfamily KQT member 3 (KQT-like 3) (Potassium channel subunit alpha KvLQT3) (Voltage-gated potassium channel subunit Kv7.3)KCNQ3O435251
Potassium voltage-gated channel, Shal-related subfamily, member 3 (Potassium voltage-gated channel, Shal-related subfamily, member 3, isoform CRA_b)KCND3 hCG_40081Q14D711
Potassium voltage-gated channel, subfamily G, member 1KCNG1Q86Y851
Potassium-transporting ATPase alpha chain 2 (EC 3.6.3.10) (Non-gastric H(+)/K(+) ATPase subunit alpha) (Proton pump)ATP12A ATP1AL1P547071
POTE ankyrin domain family member A (ANKRD26-like family A member 1) (Prostate, ovary, testis-expressed protein on chromosome 8) (POTE-8)POTEA A26A1 POTE8Q6S8J71
POTE ankyrin domain family member D (ANKRD26-like family B member 3) (Ankyrin repeat domain-containing protein 21) (Prostate, ovary, testis-expressed protein) (Protein POTE)POTED A26B3 ANKRD21 POTEQ86YR61
POTE ankyrin domain family member H (ANKRD26-like family C member 3) (Prostate, ovary, testis-expressed protein on chromosome 22) (POTE-22)POTEH A26C3 ACTBL1 POTE22Q6S5451
POU class 5 homeobox 1 transcript variant 1 (POU domain class 5 transcription factor 1 isoform 1) (POU domain transcription factor OCT4)POU5F1D2IYK31
POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (BOB-1) (OCA-B) (OCT-binding factor 1)POU2AF1 OBF1Q166331
POU domain, class 2, transcription factor 3 (Octamer-binding protein 11) (Oct-11) (Octamer-binding transcription factor 11) (OTF-11) (Transcription factor PLA-1) (Transcription factor Skn-1)POU2F3 OTF11 PLA1Q9UKI91
POU domain, class 6, transcription factor 1 (Brain-specific homeobox/POU domain protein 5) (Brain-5) (Brn-5) (mPOU homeobox protein)POU6F1 BRN5 MPOU TCFB1Q148631
POU domain, class 6, transcription factor 2 (Retina-derived POU domain factor 1) (RPF-1)POU6F2 RPF1P784241
PPP1R2 proteinPPP1R2Q6NXS21
PR domain zinc finger protein 2 (EC 2.1.1.43) (GATA-3-binding protein G3B) (Lysine N-methyltransferase 8) (MTB-ZF) (MTE-binding protein) (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc finger protein) (Zinc finger protein RIZ)PRDM2 KMT8 RIZQ130291
PR domain zinc finger protein 4 (PR domain-containing protein 4)0B3KPI01
PR domain zinc finger protein 5 (EC 2.1.1.-) (PR domain-containing protein 5)PRDM5 PFM2Q9NQX11
PRA1 family protein 2PRAF2 JM4O608311
PRAME family member 10PRAMEF10O608091
PRAME family member 2PRAMEF2O608111
PRAME family member 22PRAMEF22A3QJZ61
PRAME family member 8PRAMEF8Q5VWM41
Pre-B lymphocyte protein 3 (N27C7-2) (Protein VPreB3)VPREB3 UNQ355/PRO619Q9UKI31
Pre-mRNA-processing factor 40 homolog B (Huntingtin yeast partner C) (Huntingtin-interacting protein C)PRPF40B HYPCQ6NWY91
Pre-mRNA-splicing factor 18 (PRP18 homolog) (hPRP18)PRPF18 HPRP18Q996331
Pre-mRNA-splicing factor CWC22 homolog (Nucampholin homolog) (fSAPb)CWC22 KIAA1604 NCMQ9HCG81
pre-rRNA processing protein FTSJ3 (EC 2.1.1.-) (2'-O-ribose RNA methyltransferase SPB1 homolog) (Protein ftsJ homolog 3) (Putative rRNA methyltransferase 3)FTSJ3 SB92Q8IY811
Pre-rRNA-processing protein TSR1 homologTSR1 KIAA1401Q2NL821
Pregnancy-specific beta-1-glycoprotein 1 (PS-beta-G-1) (PSBG-1) (Pregnancy-specific glycoprotein 1) (CD66 antigen-like family member F) (Fetal liver non-specific cross-reactive antigen 1/2) (FL-NCA-1/2) (PSG95) (Pregnancy-specific beta-1 glycoprotein C/D) (PS-beta-C/D) (CD antigen CD66f)PSG1 B1G1 PSBG1 PSGGAP114641
Pregnancy-specific beta-1-glycoprotein 2 (PS-beta-G-2) (PSBG-2) (Pregnancy-specific glycoprotein 2) (Pregnancy-specific beta-1 glycoprotein E) (PS-beta-E)PSG2 PSBG2P114651
Pregnancy-specific beta-1-glycoprotein 5 (PS-beta-G-5) (PSBG-5) (Pregnancy-specific glycoprotein 5) (Fetal liver non-specific cross-reactive antigen 3) (FL-NCA-3)PSG5Q152381
Pregnancy-specific beta-1-glycoprotein 8 (PS-beta-G-8) (PSBG-8) (Pregnancy-specific glycoprotein 8)PSG8Q9UQ741
PRELI domain-containing protein 1, mitochondrial (25 kDa protein of relevant evolutionary and lymphoid interest) (Px19-like protein)PRELID1 PRELI CGI-106 SBBI12Q9Y2551
Prepronociceptin [Cleaved into: Neuropeptide 1; Nociceptin (Orphanin FQ) (PPNOC); Neuropeptide 2]PNOC OFQQ135191
Presqualene diphosphate phosphatase (EC 3.1.3.-) (Phosphatidic acid phosphatase type 2 domain-containing protein 2) (PPAP2 domain-containing protein 2)PPAPDC2Q8IY261
Prestin (Solute carrier family 26 member 5)SLC26A5 PRESP587431
Prickle-like protein 3 (LIM domain only protein 6) (LMO-6) (Triple LIM domain protein 6)PRICKLE3 LMO6O439001
Prion-like protein doppel (PrPLP) (Prion protein 2)PRND DPL UNQ1830/PRO3443Q9UKY01
Pro-interleukin-16 [Cleaved into: Interleukin-16 (IL-16) (Lymphocyte chemoattractant factor) (LCF)]IL16Q140051
Pro-neuregulin-1, membrane-bound isoform (Pro-NRG1) [Cleaved into: Neuregulin-1 (Acetylcholine receptor-inducing activity) (ARIA) (Breast cancer cell differentiation factor p45) (Glial growth factor) (Heregulin) (HRG) (Neu differentiation factor) (Sensory and motor neuron-derived factor)]NRG1 GGF HGL HRGA NDF SMDFQ022971
Pro-neuregulin-2, membrane-bound isoform (Pro-NRG2) [Cleaved into: Neuregulin-2 (NRG-2) (Divergent of neuregulin-1) (DON-1) (Neural- and thymus-derived activator for ERBB kinases) (NTAK)]NRG2 NTAKO145111
Pro-thyrotropin-releasing hormone (Pro-TRH) (Prothyroliberin) [Cleaved into: Thyrotropin-releasing hormone (TRH) (Protirelin) (TSH-releasing factor) (Thyroliberin) (Thyrotropin-releasing factor) (TRF)]TRHP203961
PRO04120Q9P1M21
Probable asparagine--tRNA ligase, mitochondrial (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS)NARS2Q96I591
Probable ATP-dependent RNA helicase DDX10 (EC 3.6.4.13) (DEAD box protein 10)DDX10Q132061
Probable ATP-dependent RNA helicase DDX4 (EC 3.6.4.13) (DEAD box protein 4) (Vasa homolog)DDX4 VASAQ9NQI01
Probable ATP-dependent RNA helicase DDX43 (EC 3.6.4.13) (Cancer/testis antigen 13) (CT13) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen)DDX43 HAGEQ9NXZ21
Probable ATP-dependent RNA helicase DDX60 (EC 3.6.4.13) (DEAD box protein 60)DDX60Q8IY211
Probable C-mannosyltransferase DPY19L2 (EC 2.4.1.-) (Dpy-19-like protein 2) (Protein dpy-19 homolog 2)DPY19L2 UNQ3127/PRO10284Q6NUT21
Probable cation-transporting ATPase 13A5 (EC 3.6.3.-) (P5-ATPase isoform 5)ATP13A5 UNQ488/PRO1004Q4VNC01
Probable crossover junction endonuclease EME2 (EC 3.1.22.-)EME2A4GXA91
Probable E3 SUMO-protein ligase RNF212 (EC 6.3.2.-) (RING finger protein 212)RNF212Q495C11
Probable E3 ubiquitin-protein ligase DTX3 (EC 6.3.2.-) (Protein deltex-3) (Deltex3) (RING finger protein 154)DTX3 RNF154Q8N9I91
Probable E3 ubiquitin-protein ligase HERC3 (EC 6.3.2.-) (HECT domain and RCC1-like domain-containing protein 3)HERC3 KIAA0032Q150341
Probable E3 ubiquitin-protein ligase MYCBP2MYCBP2J3KPZ31
Probable G-protein coupled receptor 112GPR112Q8IZF61
Probable G-protein coupled receptor 123GPR123 KIAA1828Q86SQ61
Probable G-protein coupled receptor 157GPR157Q5UAW91
Probable G-protein coupled receptor 19 (GPR-NGA)GPR19Q157601
Probable G-protein coupled receptor 27 (Super conserved receptor expressed in brain 1)GPR27 SREB1Q9NS671
Probable G-protein coupled receptor 32GPR32O753881
Probable G-protein coupled receptor 63 (PSP24-2) (PSP24-beta)GPR63 PSP24BQ9BZJ61
Probable G-protein coupled receptor 75GPR75O958001
Probable G-protein coupled receptor 82GPR82Q96P671
Probable guanine nucleotide exchange factor MCF2L2 (Dbs-related Rho family guanine nucleotide exchange factor) (MCF2-transforming sequence-like protein 2)MCF2L2 DRG KIAA0861Q86YR71
Probable helicase with zinc finger domain (EC 3.6.4.-) (Down-regulated in human cancers protein)HELZ DRHC KIAA0054P426941
Probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2 (ACC synthase-like protein 2)ACCSLQ4AC991
Probable inactive glycosyltransferase 25 family member 3 (Cerebral endothelial cell adhesion molecule)CERCAM CEECAM1 GLT25D3 KIAA1502Q5T4B21
Probable leucine--tRNA ligase, mitochondrial (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)LARS2 KIAA0028Q150311
Probable methyltransferase BTM2 homolog (EC 2.1.1.-)C7orf60Q1RMZ11
Probable palmitoyltransferase ZDHHC19 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 19) (DHHC-19)ZDHHC19Q8WVZ11
Probable peptide chain release factor C12orf65, mitochondrialC12orf65 My030Q9H3J61
Probable peptidyl-tRNA hydrolase (PTH) (EC 3.1.1.29)PTRH1 C9orf115Q86Y791
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