EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Probable phospholipid-transporting ATPase IB (EC 3.6.3.1) (ATPase class I type 8A member 2) (ML-1)ATP8A2 ATPIBQ9NTI21
Probable phospholipid-transporting ATPase IG (EC 3.6.3.1) (ATPase IQ) (ATPase class VI type 11C)ATP11C ATPIG ATPIQQ8NB491
Probable phospholipid-transporting ATPase IIB (EC 3.6.3.1) (ATPase class II type 9B)ATP9B ATPIIB NEO1L HUSSY-20O438611
Probable phospholipid-transporting ATPase VD (EC 3.6.3.1) (ATPase class V type 10D)ATP10D ATPVD KIAA1487Q9P2411
Probable proline dehydrogenase 2 (EC 1.5.99.8) (Kidney and liver proline oxidase 1) (HsPOX1) (Probable proline oxidase 2)PRODH2Q9UF121
Probable serine carboxypeptidase CPVL (EC 3.4.16.-) (Carboxypeptidase, vitellogenic-like) (Vitellogenic carboxypeptidase-like protein) (VCP-like protein) (hVLP)CPVL VLP PSEC0124 UNQ197/PRO223Q9H3G51
Probable sodium-coupled neutral amino acid transporter 6 (N-system amino acid transporter 1) (NAT-1) (Na(+)-coupled neutral amino acid transporter 6) (Solute carrier family 38 member 6)SLC38A6 NAT1 SNAT6Q8IZM91
Probable threonine protease PRSS50 (EC 3.4.25.-) (Cancer/testis antigen 20) (Serine protease 50) (Testis-specific protease-like protein 50)PRSS50 CT20 TSP50Q9UI381
Probable tRNA pseudouridine synthase 2 (EC 5.4.99.-)TRUB2O959001
Probable tubulin polyglutamylase TTLL2 (EC 6.-.-.-) (Testis-specific protein NYD-TSPG) (Tubulin--tyrosine ligase-like protein 2)TTLL2 C6orf104Q9BWV71
Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.4.19.12) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y-linked) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific protease 9, Y chromosome) (Ubiquitin-specific-processing protease FAF-Y)USP9Y DFFRYO005071
Probetacellulin [Cleaved into: Betacellulin (BTC)]BTCP350701
Processing of 1, ribonuclease P/MRP subunit (S. cerevisiae)POP1Q96F881
Profilin-3 (Profilin III)PFN3P606731
Progesterone receptor (PR) (Nuclear receptor subfamily 3 group C member 3)PGR NR3C3P064011
Progesterone-induced-blocking factor 1PIBF1 C13orf24 PIBFQ8WXW31
Programmed cell death 1 ligand 1 (PD-L1) (PDCD1 ligand 1) (Programmed death ligand 1) (B7 homolog 1) (B7-H1) (CD antigen CD274)CD274 B7H1 PDCD1L1 PDCD1LG1 PDL1Q9NZQ71
Programmed cell death protein 2PDCD2E9PCU71
Prokineticin receptor 2 (PK-R2) (G-protein coupled receptor 73-like 1) (GPR73b) (GPRg2)PROKR2 GPR73L1 PKR2Q8NFJ61
Prolactin (PRL)PRLP012361
Prolactin receptor (PRL-R)PRLRP164711
Prolactin regulatory element-binding protein (Mammalian guanine nucleotide exchange factor mSec12)PREB SEC12Q9HCU51
Prolactin-inducible protein (Gross cystic disease fluid protein 15) (GCDFP-15) (Prolactin-induced protein) (Secretory actin-binding protein) (SABP) (gp17)PIP GCDFP15 GPIP4P122731
Proline rich 11, isoform CRA_a (Transcription repressor of MHCII)PRR11 hCG_1775215D2SNZ41
Proline-rich membrane anchor 1 (PRiMA)PRIMA1Q86XR51
Proline-rich protein 1 (PRL1) (Basic proline-rich lacrimal protein) [Cleaved into: Opiorphin]PROL1 BPLPQ999351
Proline-rich protein 20APRR20A PRR20P864961
Proline-rich protein 25PRR25 gs64Q96S071
Proline-rich protein 3 (MHC class I region proline-rich protein CAT56)PRR3 CAT56P795221
Proline-rich protein 4 (Lacrimal proline-rich protein) (Nasopharyngeal carcinoma-associated proline-rich protein 4)PRR4 LPRP PROL4Q163781
Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)]LRP1 A2MR APRQ079541
Prominin-2 (PROM-2) (Prominin-like protein 2) (hPROML2)PROM2 PROML2 UNQ2521/PRO6014Q8N2711
Proprotein convertase subtilisin/kexin type 5 (EC 3.4.21.-) (Proprotein convertase 5) (PC5) (Proprotein convertase 6) (PC6) (hPC6) (Subtilisin/kexin-like protease PC5)PCSK5 PC5 PC6Q928241
Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]RLN1P048081
Prorelaxin H2 [Cleaved into: Relaxin B chain; Relaxin A chain]RLN2P040901
Prospero homeobox protein 1 (Homeobox prospero-like protein PROX1) (PROX-1)PROX1Q927861
Prostacyclin synthase (EC 5.3.99.4) (Prostaglandin I2 synthase)PTGIS CYP8 CYP8A1Q166471
Prostaglandin E synthase (EC 5.3.99.3) (Microsomal glutathione S-transferase 1-like 1) (MGST1-L1) (Microsomal prostaglandin E synthase 1) (MPGES-1) (p53-induced gene 12 protein)PTGES MGST1L1 MPGES1 PGES PIG12O146841
Prostaglandin E2 receptor EP4 subtype (PGE receptor EP4 subtype) (PGE2 receptor EP4 subtype) (Prostanoid EP4 receptor)PTGER4 PTGER2P354081
Prostaglandin F2 receptor negative regulator (CD9 partner 1) (CD9P-1) (Glu-Trp-Ile EWI motif-containing protein F) (EWI-F) (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD antigen CD315)PTGFRN CD9P1 EWIF FPRP KIAA1436Q9P2B21
Prostaglandin F2-alpha receptor (PGF receptor) (PGF2-alpha receptor) (Prostanoid FP receptor)PTGFRP430881
Prostaglandin G/H synthase 1 (EC 1.14.99.1) (Cyclooxygenase-1) (COX-1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1) (Prostaglandin-endoperoxide synthase 1)PTGS1 COX1P232191
Prostaglandin reductase 2 (PRG-2) (EC 1.3.1.48) (15-oxoprostaglandin 13-reductase) (Zinc-binding alcohol dehydrogenase domain-containing protein 1)PTGR2 ZADH1Q8N8N71
Proteasome assembly chaperone 3 (PAC-3) (hPAC3)PSMG3 C7orf48 PAC3Q9BT731
Proteasome assembly chaperone 4 (PAC-4) (hPAC4)PSMG4 C6orf86 PAC4Q5JS541
Proteasome subunit beta type (EC 3.4.25.1)0E9KL301
Protein 4.1 variant (Fragment)0Q59F121
Protein angel homolog 1ANGEL1 KIAA0759Q9UNK91
Protein ANKUB1 (cDNA FLJ59820)ANKUB1B4E2N81
Protein arginine N-methyltransferase 7 (EC 2.1.1.-) (Histone-arginine N-methyltransferase PRMT7) (EC 2.1.1.125) ([Myelin basic protein]-arginine N-methyltransferase PRMT7) (EC 2.1.1.126)PRMT7 KIAA1933Q9NVM41
Protein argonaute-3 (Argonaute3) (hAgo3) (Argonaute RISC catalytic component 3) (Eukaryotic translation initiation factor 2C 3) (eIF-2C 3) (eIF2C 3)AGO3 EIF2C3Q9H9G71
Protein argonaute-4 (Argonaute4) (hAgo4) (Argonaute RISC catalytic component 4) (Eukaryotic translation initiation factor 2C 4) (eIF-2C 4) (eIF2C 4)AGO4 EIF2C4 KIAA1567Q9HCK51
Protein artemis (EC 3.1.-.-) (DNA cross-link repair 1C protein) (Protein A-SCID) (SNM1 homolog C) (hSNM1C) (SNM1-like protein)DCLRE1C ARTEMIS ASCID SCIDA SNM1CQ96SD11
Protein atonal homolog 1 (Class A basic helix-loop-helix protein 14) (bHLHa14) (Helix-loop-helix protein hATH-1) (hATH1)ATOH1 ATH1 BHLHA14Q928581
Protein aurora borealis (HsBora)BORA C13orf34Q6PGQ71
Protein BEAN1 (Brain-expressed protein associating with Nedd4 homolog) (BEAN)BEAN1Q3B7T31
Protein BEX5 (Brain-expressed X-linked protein 5) (NGFRAP1-like protein 1) (Nerve growth factor receptor-associated protein 2)BEX5 NADE2 NGFRAP1L1Q5H9J71
Protein C9orf72C9orf72Q96LT71
Protein CASC10 (Cancer susceptibility candidate gene 10 protein)CASC10 C10orf114Q5T4H91
Protein CIP2A (Cancerous inhibitor of PP2A) (p90 autoantigen)KIAA1524 CIP2AQ8TCG11
Protein CLN8CLN8 C8orf61Q9UBY81
Protein cornichon homolog 3 (CNIH-3) (Cornichon family AMPA receptor auxiliary protein 3)CNIH3Q8TBE11
Protein CROC-4 (Contingent replication of cDNA 4)C1orf61 CROC4Q135361
Protein crumbs homolog 1CRB1P822791
Protein CYR61 (CCN family member 1) (Cysteine-rich angiogenic inducer 61) (Insulin-like growth factor-binding protein 10) (IBP-10) (IGF-binding protein 10) (IGFBP-10) (Protein GIG1)CYR61 CCN1 GIG1 IGFBP10O006221
Protein DDX26BDDX26BQ5JSJ41
Protein DENND6A (DENN domain-containing protein 6A)DENND6A FAM116AQ8IWF61
Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (MDia2)DIAPH3 DIAP3Q9NSV41
Protein dispatched homolog 1DISP1 DISPAQ96F811
Protein disulfide-isomerase A5 (EC 5.3.4.1) (Protein disulfide isomerase-related protein)PDIA5 PDIRQ145541
Protein disulfide-isomerase-like protein of the testisPDILTQ8N8071
Protein eva-1 homolog C (Protein FAM176C) (SUE21)EVA1C C21orf63 C21orf64 FAM176C PRED34 UNQ2504/PRO5993P586581
Protein EVI2B (Ecotropic viral integration site 2B protein homolog) (EVI-2B) (CD antigen CD361)EVI2B EVDBP349101
Protein eyes shut homolog (Epidermal growth factor-like protein 10) (EGF-like protein 10) (Epidermal growth factor-like protein 11) (EGF-like protein 11) (Protein spacemaker homolog)EYS C6orf178 C6orf179 C6orf180 EGFL10 EGFL11 SPAM UNQ9424/PRO34591Q5T1H11
Protein FAM102BFAM102BQ5T8I31
Protein FAM122CFAM122CQ6P4D51
Protein FAM124BFAM124BQ9H5Z61
Protein FAM126BFAM126BQ8IXS81
Protein FAM135BFAM135B C8orfK32Q49AJ01
Protein FAM160B2 (Retinoic acid-induced protein 16)FAM160B2 RAI16 FP13191Q86V871
Protein FAM163A (Cebelin) (Neuroblastoma-derived secretory protein)FAM163A C1orf76 NDSPQ96GL91
Protein FAM168A (Tongue cancer chemotherapy resistance-associated protein 1)FAM168A KIAA0280 TCRP1Q925671
Protein FAM171BFAM171B KIAA1946 NPD019Q6P9951
Protein FAM173BFAM173BQ6P4H81
Protein FAM177BFAM177BA6PVY31
Protein FAM185AFAM185AQ8N0U41
Protein FAM193A (Protein IT14)FAM193A C4orf8 RES4-22P783121
Protein FAM198B (Expressed in nerve and epithelium during development)FAM198B C4orf18 ENED AD021 UNQ2512/PRO6001Q6UWH41
Protein FAM199XFAM199X CXorf39Q6PEV81
Protein FAM19A1 (Chemokine-like protein TAFA-1)FAM19A1 TAFA1Q7Z5A91
Protein FAM19A2 (Chemokine-like protein TAFA-2)FAM19A2 TAFA2Q8N3H01
Protein FAM203A (Brain protein 16)FAM203A BRP16 C8orf30AQ9BTY71
Protein FAM209AFAM209A C20orf106Q5JX711
Protein FAM214AFAM214A KIAA1370Q32MH51
Protein FAM216AFAM216A C12orf24Q8WUB21
Protein FAM222BFAM222B C17orf63Q8WU581
Protein FAM24AFAM24AA6NFZ41
Protein FAM24BFAM24BQ8N5W81
Protein FAM49AFAM49AQ9H0Q01
Protein FAM49B (L1)FAM49B BM-009Q9NUQ91
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