EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
RecQ-mediated genome instability protein 2 (hRMI2) (BLM-associated protein of 18 kDa) (BLAP18)RMI2 C16orf75Q96E141
Regenerating islet-derived protein 3-alpha (REG-3-alpha) (Hepatointestinal pancreatic protein) (HIP/PAP) (Human proislet peptide) (Pancreatitis-associated protein 1) (Regenerating islet-derived protein III-alpha) (Reg III-alpha) [Cleaved into: Regenerating islet-derived protein 3-alpha 16.5 kDa form; Regenerating islet-derived protein 3-alpha 15 kDa form]REG3A HIP PAP PAP1Q061411
Regenerating islet-derived protein 3-gamma (REG-3-gamma) (Pancreatitis-associated protein 1B) (PAP-1B) (Pancreatitis-associated protein IB) (PAP IB) (Regenerating islet-derived protein III-gamma) (REG III) (Reg III-gamma) [Cleaved into: Regenerating islet-derived protein 3-gamma 16.5 kDa form; Regenerating islet-derived protein 3-gamma 15 kDa form]REG3G PAP1B UNQ429/PRO162Q6UW151
Regulator of G-protein signaling 14 (RGS14)RGS14O435661
Regulator of G-protein signaling 22 (RGS22)RGS22Q8NE091
Regulator of G-protein signaling 4 (RGP4) (RGS4)RGS4P497981
Regulator of G-protein signaling 7 (RGS7)RGS7P498021
Regulator of G-protein signaling 8 (RGS8)RGS8P577711
Regulator of G-protein signalling 3, isoform CRA_i (Regulator of G-protein-signaling 3)RGS3 hCG_29191H7BXY11
Regulator of microtubule dynamics protein 1 (RMD-1) (hRMD-1) (Protein FAM82B)RMDN1 FAM82B CGI-90Q96DB51
RELT-like protein 1RELL1 PSEC0162Q8IUW51
Replication protein A 30 kDa subunit (RP-A p30) (Replication factor A protein 4) (RF-A protein 4)RPA4Q131561
REST corepressor 1 (REST corepressor 1, isoform CRA_a)RCOR1 hCG_24743J3KN321
REST corepressor 2RCOR2Q8IZ401
Ret finger protein-like 3RFPL3O756791
Reticulon-4 receptor (Nogo receptor) (NgR) (Nogo-66 receptor)RTN4R NOGOR UNQ330/PRO526Q9BZR61
Reticulon-4-interacting protein 1, mitochondrial (NOGO-interacting mitochondrial protein)RTN4IP1 NIMPQ8WWV31
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma (GMP-PDE gamma) (EC 3.1.4.35)PDE6HQ139561
Retinal guanylyl cyclase 1 (RETGC-1) (EC 4.6.1.2) (Guanylate cyclase 2D, retinal) (Rod outer segment membrane guanylate cyclase) (ROS-GC)GUCY2D CORD6 GUC1A4 GUC2D RETGC RETGC1Q028461
Retinitis pigmentosa 1-like 1 proteinRP1L1A6NKC61
Retinoblastoma-like 2 (P130)RBL2Q8NE701
Retinoic acid early transcript 1G proteinRAET1GQ6H3X31
Retinoic acid nuclear receptor alpha variant 2 (Retinoic acid receptor, alpha, isoform CRA_b)NR1B1 RARA hCG_2007196F1D8N91
Retinoic acid receptor beta (RAR-beta) (HBV-activated protein) (Nuclear receptor subfamily 1 group B member 2) (RAR-epsilon)RARB HAP NR1B2P108261
Retinoic acid receptor responder protein 1 (RAR-responsive protein TIG1) (Tazarotene-induced gene 1 protein)RARRES1 TIG1P497881
Retinoic acid receptor responder protein 2 (RAR-responsive protein TIG2) (Tazarotene-induced gene 2 protein)RARRES2 TIG2Q999691
Retinol-binding protein 3 (Interphotoreceptor retinoid-binding protein) (IRBP) (Interstitial retinol-binding protein)RBP3P107451
Retrotransposon gag domain-containing protein 1 (Tumor antigen BJ-HCC-23)RGAG1 KIAA1318Q8NET41
Retroviral-like aspartic protease 1 (EC 3.4.23.-) (Skin-specific retroviral-like aspartic protease) (SASPase) (Skin aspartic protease) (TPA-inducible aspartic proteinase-like protein) (TAPS)ASPRV1 SASPQ53RT31
RFWD2 protein (Fragment)RFWD2Q05CT61
Rho GTPase-activating protein 15 (ArhGAP15) (Rho-type GTPase-activating protein 15)ARHGAP15 BM-024 BM-030 BM-046Q53QZ31
Rho GTPase-activating protein 31 (Cdc42 GTPase-activating protein)ARHGAP31 CDGAP KIAA1204Q2M1Z31
Rho GTPase-activating protein 32 (Brain-specific Rho GTPase-activating protein) (GAB-associated Cdc42/Rac GTPase-activating protein) (GC-GAP) (GTPase regulator interacting with TrkA) (Rho-type GTPase-activating protein 32) (Rho/Cdc42/Rac GTPase-activating protein RICS) (RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling) (p200RhoGAP) (p250GAP)ARHGAP32 GRIT KIAA0712 RICSA7KAX91
Rho GTPase-activating protein 42 (Rho GTPase-activating protein 10-like) (Rho-type GTPase-activating protein 42)ARHGAP42A6NI281
Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF)ARHGEF11 KIAA0380O150851
Rho-related GTP-binding protein RhoV (CDC42-like GTPase 2) (GTP-binding protein-like 2) (Rho GTPase-like protein ARHV) (Wnt-1 responsive Cdc42 homolog 2) (WRCH-2)RHOV ARHV WRCH2Q96L331
Rhomboid domain-containing protein 3RHBDD3 C22orf3Q9Y3P41
Rhomboid-related protein 2, C-terminal fragment (cDNA FLJ40302 fis, clone TESTI2029196, highly similar to Rhomboid-related protein 2 (EC 3.4.21.105))RHBDL2B3KUN41
Rhombotin-1 (Cysteine-rich protein TTG-1) (LIM domain only protein 1) (LMO-1) (T-cell translocation protein 1)LMO1 RBTN1 RHOM1 TTG1P258001
Rhophilin-1 (GTP-Rho-binding protein 1)RHPN1 KIAA1929Q8TCX51
Rhox homeobox family member 1 (Ovary-, testis- and epididymis-expressed gene protein) (Paired-like homeobox protein PEPP-1)RHOXF1 OTEX PEPP1Q8NHV91
RIB43A-like with coiled-coils protein 1RIBC1Q8N4431
Ribonuclease 3 (EC 3.1.26.3) (Protein Drosha) (Ribonuclease III) (RNase III) (p241)DROSHA RN3 RNASE3L RNASENQ9NRR41
Ribonuclease H1 (RNase H1) (EC 3.1.26.4) (Ribonuclease H type II)RNASEH1 RNH1O609301
Ribonuclease P protein subunit p25 (RNase P protein subunit p25) (EC 3.1.26.5)RPP25Q9BUL91
Ribonucleoprotein PTB-binding 1 (Protein raver-1)RAVER1 KIAA1978Q8IY671
Ribonucleoside-diphosphate reductase subunit M2 B (EC 1.17.4.1) (TP53-inducible ribonucleotide reductase M2 B) (p53-inducible ribonucleotide reductase small subunit 2-like protein) (p53R2)RRM2B P53R2Q7LG561
Ribose-5-phosphate isomerase (EC 5.3.1.6) (Phosphoriboisomerase)RPIA RPIP492471
Ribosomal protein L3RPL3Q96QL01
Ribosomal RNA processing protein 1 homolog A (Novel nuclear protein 1) (NNP-1) (Nucleolar protein Nop52) (RRP1-like protein)RRP1 D21S2056E NNP1 NOP52 RRP1AP561821
Ribosomal RNA processing protein 1 homolog B (RRP1-like protein B)RRP1B KIAA0179Q146841
Ribosomal RNA-processing protein 8 (EC 2.1.1.-) (Cerebral protein 1) (Nucleomethylin)RRP8 KIAA0409 NML hucep-1O431591
RIMS1 protein (Fragment)RIMS1Q3ZCW01
RIN2 proteinRIN2A1A4T01
RING finger and CHY zinc finger domain-containing protein 1 (EC 6.3.2.-) (Androgen receptor N-terminal-interacting protein) (CH-rich-interacting match with PLAG1) (E3 ubiquitin-protein ligase Pirh2) (RING finger protein 199) (Zinc finger protein 363) (p53-induced RING-H2 protein) (hPirh2)RCHY1 ARNIP CHIMP PIRH2 RNF199 ZNF363Q96PM51
RING finger and transmembrane domain-containing protein 2RNFT2E9PAM71
RING finger protein 112 (Brain finger protein) (Zinc finger protein 179)RNF112 BFP ZNF179Q9ULX51
RING finger protein 113B (Zinc finger protein 183-like 1)RNF113B RNF161 ZNF183L1Q8IZP61
RING finger protein 122RNF122Q9H9V41
Ring finger protein 148 (Ring finger protein 148, isoform CRA_b)RNF148 hCG_2013925 tcag7.1312A4D0X41
RING finger protein 150RNF150 KIAA1214Q9ULK61
RING finger protein 166RNF166Q96A371
RING finger protein 175RNF175Q8N4F71
RING finger protein 183RNF183Q96D591
RING finger protein 207RNF207 C1orf188Q6ZRF81
RING finger protein 215RNF215Q9Y6U71
RING finger protein 219RNF219 C13orf7Q5W0B11
RING finger protein 24RNF24Q9Y2251
RNA 3'-terminal phosphate cyclase-like proteinRCL1 RNAC RPC2 RPCL1 RTC2 HSPC338Q9Y2P81
RNA binding motif protein 17, isoform CRA_a (cDNA, FLJ95864)RBM17 hCG_24832Q5W0091
RNA binding motif protein, X-linked-like-1 (Heterogeneous nuclear ribonucleoprotein G-like 1)RBMXL1Q96E391
RNA binding protein (Autoantigenic, hnRNP-associated with lethal yellow) long isoform variant (RNA binding protein, autoantigenic (HnRNP-associated with lethal yellow homolog (Mouse))) (RNA binding protein, autoantigenic (HnRNP-associated with lethal yellow homolog (Mouse)), isoform CRA_a) (cDNA FLJ77422, highly similar to Homo sapiens RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)), transcript variant 1, mRNA) (Fragment)RALY hCG_37136Q53GL61
RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein)ELL C19orf17P551991
RNA polymerase II elongation factor ELL2ELL2O004721
RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase)CTDP1 FCP1Q9Y5B01
RNA polymerase-associated protein LEO1 (Replicative senescence down-regulated leo1-like protein)LEO1 RDLQ8WVC01
RNA-binding protein 26 (CTCL tumor antigen se70-2) (RNA-binding motif protein 26)RBM26 C13orf10 PRO1777Q5T8P61
RNA-binding protein 33 (Proline-rich protein 8) (RNA-binding motif protein 33)RBM33 PRR8Q96EV21
RNA-binding protein 40 (RNA-binding motif protein 40) (RNA-binding region-containing protein 3) (U11/U12 small nuclear ribonucleoprotein 65 kDa protein) (U11/U12 snRNP 65 kDa protein) (U11/U12-65K)RNPC3 KIAA1839 RBM40 RNPQ96LT91
RNA-binding protein 43 (RNA-binding motif protein 43)RBM43 C2orf38Q6ZSC31
RNA-binding protein 7 (RNA-binding motif protein 7)RBM7Q9Y5801
RNA-binding protein MEX3B (RING finger and KH domain-containing protein 3) (RING finger protein 195)MEX3B KIAA2009 RKHD3 RNF195Q6ZN041
RNA-binding Raly-like protein (hRALYL) (Heterogeneous nuclear ribonucleoprotein C-like 3) (hnRNP core protein C-like 3)RALYL HNRPCL3Q86SE51
RNASEH2B proteinRNASEH2BQ8N4511
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta (GMP-PDE beta) (EC 3.1.4.35)PDE6B PDEBP359131
Ropporin-1-like protein (ROPN1-like protein) (AKAP-associated sperm protein)ROPN1L ASPQ96C741
Ropporin-1A (Cancer/testis antigen 91) (CT91) (Rhophilin-associated protein 1A)ROPN1 ROPN1AQ9HAT01
Roundabout homolog 2ROBO2 KIAA1568Q9HCK41
Roundabout homolog 3 (Roundabout-like protein 3)ROBO3Q96MS01
Roundabout homolog 4 (Magic roundabout)ROBO4 UNQ421/PRO3674Q8WZ751
RPE-retinal G protein-coupled receptorRGRP478041
RPS6KA4 protein (Fragment)RPS6KA4A0PJF81
RSF1 protein (Fragment)RSF1Q05DG01
RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (La-binding protein 1) (Rab4-interacting protein) (Zinc finger FYVE domain-containing protein 12)RUFY1 RABIP4 ZFYVE12Q96T511
RUN and TBC1 domain-containing protein 3RUTBC3B9A6J51
Runt-related transcription factor 2 (Acute myeloid leukemia 3 protein) (Core-binding factor subunit alpha-1) (CBF-alpha-1) (Oncogene AML-3) (Osteoblast-specific transcription factor 2) (OSF-2) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEA2-alpha A) (PEBP2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit)RUNX2 AML3 CBFA1 OSF2 PEBP2AQ139501
RWD domain-containing protein 4 (Protein FAM28A)RWDD4 FAM28A RWDD4AQ6NW291
RXRA protein (Fragment)RXRAQ6P3U71
Ryanodine receptor 1 (RYR-1) (RyR1) (Skeletal muscle calcium release channel) (Skeletal muscle ryanodine receptor) (Skeletal muscle-type ryanodine receptor) (Type 1 ryanodine receptor)RYR1 RYDRP218171
Ryanodine receptor 2 (RYR-2) (RyR2) (hRYR-2) (Cardiac muscle ryanodine receptor) (Cardiac muscle ryanodine receptor-calcium release channel) (Type 2 ryanodine receptor)RYR2Q927361
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