EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Sex-determining region Y protein (Testis-determining factor)SRY TDFQ050661
SF3B1 protein (Fragment)SF3B1Q7Z4971
SFRS protein kinase 1, isoform CRA_f (SRSF protein kinase 1) (cDNA FLJ58405, highly similar to Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1))SRPK1 hCG_15775B4DS611
SFRS17A protein (Fragment)SFRS17AQ05DA91
SH2 domain-containing protein 1B (EWS/FLI1-activated transcript 2) (EAT-2)SH2D1B EAT2O147961
SH2 domain-containing protein 3A (Novel SH2-containing protein 1)SH2D3A NSP1 UNQ175/PRO201Q9BRG21
SH2 domain-containing protein 4BSH2D4BQ5SQS71
SH2 domain-containing protein 5SH2D5Q6ZV891
SH3 and cysteine rich domain 2, isoform CRA_b (SH3 and cysteine-rich domain-containing protein 2)STAC2 hCG_31410D0IN091
SH3 and cysteine-rich domain-containing protein 3STAC3Q96MF21
SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP)SHANK1Q9Y5661
SH3 and PX domain-containing protein 2B (Adapter protein HOFI) (Factor for adipocyte differentiation 49) (Tyrosine kinase substrate with four SH3 domains)SH3PXD2B FAD49 KIAA1295 TKS4A1X2831
SH3 domain containing ring finger 2SH3RF2Q08AM81
Shadow of prion protein (Protein shadoo)SPRN SHOQ5BIV91
SHC-transforming protein 2 (Protein Sck) (SHC-transforming protein B) (Src homology 2 domain-containing-transforming protein C2) (SH2 domain protein C2)SHC2 SCK SHCBP980771
SHC-transforming protein 4 (Rai-like protein) (RaLP) (SHC-transforming protein D) (hShcD) (Src homology 2 domain-containing-transforming protein C4) (SH2 domain protein C4)SHC4 SHCD UNQ6438/PRO21364Q6S5L81
Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (TRP-1)TRPC1 TRP1P489951
Short transient receptor potential channel 4 (TrpC4) (Trp-related protein 4) (hTrp-4) (hTrp4)TRPC4Q9UBN41
Short transient receptor potential channel 4-associated protein (Trp4-associated protein) (Trpc4-associated protein) (Protein TAP1) (TNF-receptor ubiquitous scaffolding/signaling protein) (Protein TRUSS)TRPC4AP C20orf188 TRRP4APQ8TEL61
Short transient receptor potential channel 6 (TrpC6) (Transient receptor protein 6) (TRP-6)TRPC6 TRP6Q9Y2101
Short transient receptor potential channel 7 (TrpC7) (Transient receptor protein 7) (TRP-7) (hTRP7)TRPC7 TRP7Q9HCX41
Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial (SBCAD) (EC 1.3.8.5) (2-methyl branched chain acyl-CoA dehydrogenase) (2-MEBCAD) (2-methylbutyryl-coenzyme A dehydrogenase) (2-methylbutyryl-CoA dehydrogenase)ACADSBP459541
Shugoshin-like 2 (Shugoshin-2) (Sgo2) (Tripin)SGOL2Q562F61
Sialic acid-binding Ig-like lectin 10 (Siglec-10) (Siglec-like protein 2)SIGLEC10 SLG2 UNQ477/PRO940Q96LC71
Sialic acid-binding Ig-like lectin 9 (Siglec-9) (CDw329) (Protein FOAP-9) (CD antigen CD329)SIGLEC9 UNQ668/PRO1302Q9Y3361
SIAT4C protein (ST3 beta-galactoside alpha-2,3-sialyltransferase 4, isoform CRA_c) (cDNA, FLJ95600, Homo sapiens sialyltransferase 4C (beta-galactosidealpha-2,3-sialyltransferase) (SIAT4C), mRNA)SIAT4C ST3GAL4 hCG_37591Q6IBE61
Sideroflexin-5SFXN5Q8TD221
Sigma non-opioid intracellular receptor 1 (Aging-associated gene 8 protein) (SR31747-binding protein) (SR-BP) (Sigma 1-type opioid receptor) (SIG-1R) (Sigma1-receptor) (Sigma1R) (hSigmaR1)SIGMAR1 OPRS1 SRBP AAG8Q997201
Signal peptide peptidase-like 2A (SPP-like 2A) (SPPL2a) (EC 3.4.23.-) (Intramembrane protease 3) (IMP-3) (Presenilin-like protein 2)SPPL2A IMP3 PSL2 PSEC0147Q8TCT81
Signal recognition particle receptor beta subunit (Signal recognition particle receptor, B subunit, isoform CRA_b)SRPRB hCG_2023561Q549N51
Signal transducer and activator of transcription (Fragment)0Q59GY71
Signal-regulatory protein beta-1 (SIRP-beta-1) (CD172 antigen-like family member B) (CD antigen CD172b)SIRPB1O002411
Signal-regulatory protein beta-2 (SIRP-beta-2) (Protein tyrosine phosphatase non-receptor type substrate 1-like 3) (Protein tyrosine phosphatase non-receptor type substrate protein)SIRPB2 PTPN1L PTPNS1L3Q5JXA91
Signal-regulatory protein delta (SIRP-delta) (Protein tyrosine phosphatase non-receptor type substrate 1-like 2)SIRPD PTPNS1L2Q9H1061
Single-minded homolog 2 (Class E basic helix-loop-helix protein 15) (bHLHe15)SIM2 BHLHE15Q141901
Single-stranded DNA cytosine deaminase (EC 3.5.4.38) (Activation-induced cytidine deaminase) (Cytidine aminohydrolase)AICDA AIDQ9GZX71
Single-stranded DNA-binding protein 2 (Sequence-specific single-stranded-DNA-binding protein 2)SSBP2 SSDP2P818771
SKI family transcriptional corepressor 1 (Functional Smad-suppressing element on chromosome 15) (Fussel-15) (LBX1 corepressor 1) (Ladybird homeobox corepressor 1)SKOR1 CORL1 FUSSEL15 LBXCOR1P845501
SLAM family member 5 (Cell surface antigen MAX.3) (Hly9-beta) (Leukocyte differentiation antigen CD84) (Signaling lymphocytic activation molecule 5) (CD antigen CD84)CD84 SLAMF5Q9UIB81
SLAM family member 9 (CD2 family member 10) (CD2F-10) (CD84 homolog 1) (CD84-H1)SLAMF9 CD2F10 UNQ1938/PRO4421Q96A281
SLC25A11 protein (Solute carrier family 25 (Mitochondrial carrier; oxoglutarate carrier), member 11, isoform CRA_b) (cDNA FLJ76014, highly similar to Homo sapiens solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 (SLC25A11), mRNA)SLC25A11 hCG_32694Q6IBH01
SLC2A4 protein (Solute carrier family 2, facilitated glucose transporter member 4)SLC2A4Q05BQ31
SLC31A2 protein (Solute carrier family 31 (Copper transporters), member 2) (Fragment)SLC31A2 hCG_29184Q53X941
SLIT and NTRK-like protein 2SLITRK2 CXorf2 KIAA1854 SLITL1 UNQ9197/PRO34756Q9H1561
SLIT and NTRK-like protein 3SLITRK3 KIAA0848O949331
SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho GTPase-activating protein 13)SRGAP1 ARHGAP13 KIAA1304Q7Z6B71
SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (Mental disorder-associated GAP) (Rho GTPase-activating protein 14) (WAVE-associated Rac GTPase-activating protein) (WRP)SRGAP3 ARHGAP14 KIAA0411 KIAA1156 MEGAP SRGAP2O432951
SLP adapter and CSK-interacting membrane protein (SLP65/SLP76, Csk-interacting membrane protein)SCIMP C17orf87 UNQ5783/PRO16090Q6UWF31
Small conductance calcium-activated potassium channel protein 3 (SK3) (SKCa 3) (SKCa3) (KCa2.3)KCNN3 K3Q9UGI61
Small G protein signaling modulator 1 (RUN and TBC1 domain-containing protein 2)SGSM1 KIAA1941 RUTBC2Q2NKQ11
Small glutamine-rich tetratricopeptide repeat-containing protein beta (Beta-SGT) (Small glutamine-rich protein with tetratricopeptide repeats 2)SGTB SGT2Q96EQ01
Small integral membrane protein 13SMIM13 C6orf228P0DJ931
Small integral membrane protein 8SMIM8 C6orf162 DC18Q96KF71
Small kinetochore-associated protein (SKAP) (Kinetochore-localized astrin-binding protein) (Kinastrin) (Kinetochore-localized astrin/SPAG5-binding protein) (TRAF4-associated factor 1)KNSTRN C15orf23 SKAP TRAF4AF1 HSD11Q9Y4481
Small proline-rich protein 2B (SPR-2B)SPRR2BP353251
Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II)SPRR2EP225311
SMARCA1 protein (Fragment)SMARCA1Q86UA81
SMURF2 protein (Fragment)SMURF2Q96DE71
Sn1-specific diacylglycerol lipase alpha (DGL-alpha) (EC 3.1.1.-) (Neural stem cell-derived dendrite regulator)DAGLA C11orf11 KIAA0659 NSDDRQ9Y4D21
Sn1-specific diacylglycerol lipase beta (DGL-beta) (EC 3.1.1.-) (KCCR13L)DAGLBQ8NCG71
SNX26 proteinSNX26A1A5D21
Sodium bicarbonate transporter-like protein 11 (Bicarbonate transporter-related protein 1) (Sodium borate cotransporter 1) (NaBC1) (Solute carrier family 4 member 11)SLC4A11 BTR1Q8NBS31
Sodium channel protein type 1 subunit alpha (Sodium channel protein brain I subunit alpha) (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1)SCN1A NAC1 SCN1P354981
Sodium channel protein type 4 subunit alpha (SkM1) (Sodium channel protein skeletal muscle subunit alpha) (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4)SCN4AP354991
Sodium channel subunit beta-3SCN3B KIAA1158Q9NY721
Sodium leak channel non-selective protein (CanIon) (Voltage gated channel-like protein 1)NALCN VGCNL1Q8IZF01
Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13)SLC6A13 GAT2Q9NSD51
Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) (Amino acid transporter ATB0+) (Solute carrier family 6 member 14)SLC6A14Q9UN761
Sodium- and chloride-dependent transporter XTRP3 (Sodium/imino-acid transporter 1) (Solute carrier family 6 member 20) (Transporter rB21A homolog)SLC6A20 SIT1 XT3 XTRP3Q9NP911
Sodium-coupled neutral amino acid transporter 3 (N-system amino acid transporter 1) (Na(+)-coupled neutral amino acid transporter 3) (Solute carrier family 38 member 3) (System N amino acid transporter 1)SLC38A3 G17 NAT1 SN1 SNAT3Q996241
Sodium-dependent glucose transporter 1NAGLT1 KIAA1919 HSPC100Q5TF391
Sodium-dependent neutral amino acid transporter B(0)AT2 (Sodium- and chloride-dependent neurotransmitter transporter NTT73) (Sodium-coupled branched-chain amino-acid transporter 1) (Solute carrier family 6 member 15) (Transporter v7-3)SLC6A15 B0AT2 NTT73 SBAT1Q9H2J71
Sodium-dependent neutral amino acid transporter B(0)AT3 (Sodium- and chloride-dependent transporter XTRP2) (Solute carrier family 6 member 18) (System B(0) neutral amino acid transporter AT3)SLC6A18 XTRP2Q96N871
Sodium-dependent noradrenaline transporter (Norepinephrine transporter) (NET) (Solute carrier family 6 member 2)SLC6A2 NAT1 NET1 SLC6A5P239751
Sodium-dependent phosphate transport protein 2B (Sodium-phosphate transport protein 2B) (Na(+)-dependent phosphate cotransporter 2B) (NaPi3b) (Sodium/phosphate cotransporter 2B) (Na(+)/Pi cotransporter 2B) (NaPi-2b) (Solute carrier family 34 member 2)SLC34A2O954361
Sodium-dependent phosphate transport protein 3 (Na(+)/PI cotransporter 3) (Sodium/phosphate cotransporter 3) (Solute carrier family 17 member 2)SLC17A2 NPT3O006241
Sodium-driven chloride bicarbonate exchanger (Solute carrier family 4 member 10)SLC4A10 NCBEQ6U8411
Sodium/bile acid cotransporter 4 (Na(+)/bile acid cotransporter 4) (Solute carrier family 10 member 4)SLC10A4Q96EP91
Sodium/bile acid cotransporter 5 (Na(+)/bile acid cotransporter 5) (Solute carrier family 10 member 5)SLC10A5Q5PT551
Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1)SLC8A1 CNC NCX1P324181
Sodium/calcium exchanger 2 (Na(+)/Ca(2+)-exchange protein 2) (Solute carrier family 8 member 2)SLC8A2 KIAA1087 NCX2Q9UPR51
Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3)SLC8A3 NCX3P571031
Sodium/hydrogen exchanger 5 (Na(+)/H(+) exchanger 5) (NHE-5) (Solute carrier family 9 member 5)SLC9A5 NHE5Q149401
Sodium/hydrogen exchanger 8 (Na(+)/H(+) exchanger 8) (NHE-8) (Solute carrier family 9 member 8)SLC9A8 KIAA0939 NHE8Q9Y2E81
Sodium/hydrogen exchanger 9 (Na(+)/H(+) exchanger 9) (NHE-9) (Solute carrier family 9 member 9)SLC9A9 NHE9 Nbla00118Q8IVB41
Sodium/nucleoside cotransporter 2 (Concentrative nucleoside transporter 2) (CNT 2) (hCNT2) (Na(+)/nucleoside cotransporter 2) (Sodium-coupled nucleoside transporter 2) (Sodium/purine nucleoside co-transporter) (SPNT) (Solute carrier family 28 member 2)SLC28A2 CNT2O438681
Sodium/potassium-transporting ATPase subunit alpha-3 (Na(+)/K(+) ATPase alpha-3 subunit) (EC 3.6.3.9) (Na(+)/K(+) ATPase alpha(III) subunit) (Sodium pump subunit alpha-3)ATP1A3P136371
Sodium/potassium-transporting ATPase subunit alpha-4 (Na(+)/K(+) ATPase alpha-4 subunit) (EC 3.6.3.9) (Sodium pump subunit alpha-4)ATP1A4 ATP1AL2Q137331
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2 (Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 2) (Protein FAM77B) (T-cell lymphoma breakpoint-associated target protein 1)NKAIN2 FAM77B TCBA1Q5VXU11
Sodium/potassium/calcium exchanger 5 (Na(+)/K(+)/Ca(2+)-exchange protein 5) (Solute carrier family 24 member 5)SLC24A5 JSX NCKX5Q71RS61
Solute carrier family 12 member 1 (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2) (Kidney-specific Na-K-Cl symporter)SLC12A1 NKCC2Q136211
Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (hKCC1)SLC12A4 KCC1Q9UP951
Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4)SLC12A7 KCC4Q9Y6661
Solute carrier family 13 member 2 (Na(+)/dicarboxylate cotransporter 1) (NaDC-1) (Renal sodium/dicarboxylate cotransporter)SLC13A2 NADC1 SDCT1Q131831
Solute carrier family 13 member 4 (Na(+)/sulfate cotransporter SUT-1) (NaS2)SLC13A4 SUT1Q9UKG41
Solute carrier family 13 member 5 (Na(+)/citrate cotransporter) (NaCT) (Sodium-coupled citrate transporter) (Sodium-dependent citrate transporter)SLC13A5 NACTQ86YT51
Solute carrier family 15 oligopeptide transporter member 10B2CQT61
Solute carrier family 2, facilitated glucose transporter member 4 (Glucose transporter type 4, insulin-responsive) (GLUT-4)SLC2A4 GLUT4P146721
Solute carrier family 22 member 13 (Organic cation transporter-like 3) (ORCTL-3)SLC22A13 ORCTL3Q9Y2261
Solute carrier family 22 member 14 (Organic cation transporter-like 4) (ORCTL-4)SLC22A14 ORCTL4Q9Y2671
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