EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Transcription factor 15 (TCF-15) (Class A basic helix-loop-helix protein 40) (bHLHa40) (Paraxis) (Protein bHLH-EC2)TCF15 BHLHA40 BHLHEC2Q128701
Transcription factor 7-like 2 (HMG box transcription factor 4) (T-cell-specific transcription factor 4) (T-cell factor 4) (TCF-4) (hTCF-4)TCF7L2 TCF4Q9NQB01
Transcription factor AP-4 (Activating enhancer-binding protein 4) (Class C basic helix-loop-helix protein 41) (bHLHc41)TFAP4 BHLHC41Q016641
Transcription factor Dp family member 3 (Cancer/testis antigen 30) (CT30) (Hepatocellular carcinoma-associated antigen 661)TFDP3 DP4 HCA661Q5H9I01
Transcription factor E2F2 (E2F-2)E2F2Q142091
Transcription factor E2F5 (E2F-5)E2F5Q153291
Transcription factor E2F7 (E2F-7)E2F7Q96AV81
Transcription factor HES-2 (Class B basic helix-loop-helix protein 40) (bHLHb40) (Hairy and enhancer of split 2)HES2 BHLHB40Q9Y5431
Transcription factor HES-3 (Class B basic helix-loop-helix protein 43) (bHLHb43) (Hairy and enhancer of split 3)HES3 BHLHB43Q5TGS11
Transcription factor HES-5 (Class B basic helix-loop-helix protein 38) (bHLHb38) (Hairy and enhancer of split 5)HES5 BHLHB38Q5TA891
Transcription factor HIVEP3 (Human immunodeficiency virus type I enhancer-binding protein 3) (Kappa-B and V(D)J recombination signal sequences-binding protein) (Kappa-binding protein 1) (KBP-1) (Zinc finger protein ZAS3)HIVEP3 KBP1 KIAA1555 KRC ZAS3Q5T1R41
Transcription factor MafA (Pancreatic beta-cell-specific transcriptional activator) (Transcription factor RIPE3b1) (V-maf musculoaponeurotic fibrosarcoma oncogene homolog A)MAFAQ8NHW31
Transcription factor NF-E4NFE4Q86UQ81
Transcription factor SOX-13 (Islet cell antigen 12) (SRY (Sex determining region Y)-box 13) (Type 1 diabetes autoantigen ICA12)SOX13Q9UN791
Transcription factor SOX-2SOX2P484311
Transcription factor SOX-21 (SOX-A)SOX21 SOX25 SOXAQ9Y6511
Transcription factor Spi-BSPIBQ018921
Transcription initiation factor IIA subunit 20B2R5061
Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Cell cycle gene 1 protein) (TBP-associated factor 250 kDa) (p250) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250)TAF1 BA2R CCG1 CCGS TAF2AP216751
Transcription initiation factor TFIID subunit 1-like (TAF(II)210) (TBP-associated factor 1-like) (TBP-associated factor 210 kDa) (Transcription initiation factor TFIID 210 kDa subunit)TAF1LQ8IZX41
Transcription initiation factor TFIID subunit 6 (RNA polymerase II TBP-associated factor subunit E) (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII70) (Transcription initiation factor TFIID 80 kDa subunit) (TAF(II)80) (TAFII-80) (TAFII80)TAF6 TAF2E TAFII70P498481
Transcription initiation protein SPT3 homolog (SPT3-like protein)SUPT3H SPT3O754861
Transcription regulator protein BACH2 (BTB and CNC homolog 2)BACH2Q9BYV91
Transcription termination factor, mitochondrial (Mitochondrial transcription termination factor 1) (mTERF)MTERFQ995511
Transcriptional activator Myb (Proto-oncogene c-Myb)MYBP102421
Transcriptional adapter 2-beta (ADA2-like protein beta) (ADA2-beta)TADA2B ADA2BQ86TJ21
Transcriptional regulator ERG (Transforming protein ERG)ERGP113081
Transcriptional repressor scratch 2 (Scratch homolog 2 zinc finger protein)SCRT2 FP7030Q9NQ031
Transcriptional-regulating factor 1 (Breast cancer anti-estrogen resistance 2) (Transcriptional-regulating protein 132) (Zinc finger protein rapa) (Zinc finger transcription factor TReP-132)TRERF1 BCAR2 RAPA TREP132Q96PN71
Transducin beta-like protein 2 (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosomal region 13 protein)TBL2 WBSCR13 UNQ563/PRO1125Q9Y4P31
Transducin-like enhancer protein 6TLE6Q9H8081
Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A)TRA2AQ135951
Transforming acidic coiled-coil-containing protein 3 (ERIC-1)TACC3 ERIC1Q9Y6A51
Transforming growth factor beta receptor type 3 (TGF-beta receptor type 3) (TGFR-3) (Betaglycan) (Transforming growth factor beta receptor III) (TGF-beta receptor type III)TGFBR3Q031671
Transforming growth factor beta regulator 1 (Nuclear interactor of ARF and Mdm2)TBRG1 NIAMQ3YBR21
Transforming growth factor, beta receptor II (70/80kDa) isoform 2TGFBR2D2JYI11
Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation-sensitive protein p120)TRPA1 ANKTM1O757621
Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Channel-kinase 1) (Long transient receptor potential channel 7) (LTrpC-7) (LTrpC7)TRPM7 CHAK1 LTRPC7Q96QT41
Transient receptor potential cation channel subfamily V member 2 (TrpV2) (Osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1)TRPV2 VRLQ9Y5S11
Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3)TRPV3Q8NET81
Transient receptor potential cation channel subfamily V member 5 (TrpV5) (Calcium transport protein 2) (CaT2) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Osm-9-like TRP channel 3) (OTRPC3)TRPV5 ECAC1Q9NQA51
Transketolase-like protein 2 (EC 2.2.1.1)TKTL2Q9H0I91
Translation machinery-associated protein 16TMA16 C4orf43Q96EY41
Translin-associated factor X-interacting protein 1 (Trax-interacting protein 1)TSNAXIP1 TXI1Q2TAA81
Translocase of inner mitochondrial membrane domain-containing protein 1 (Protein M5-14)TIMMDC1 C3orf1 UNQ247/PRO284Q9NPL81
Translocating chain-associated membrane protein 2TRAM2 KIAA0057Q150351
Translocation protein SEC63 homologSEC63 SEC63LQ9UGP81
Translocator protein 2 (Peripheral-type benzodiazepine receptor-like protein 1)TSPO2 BZRPL1Q5TGU01
Transmembrane 7 superfamily member 3 (Seven span transmembrane protein)TM7SF3Q9NS931
Transmembrane and coiled-coil domains protein 1TMCC1 KIAA0779O948761
Transmembrane and coiled-coil domains protein 3TMCC3 KIAA1145Q9ULS51
Transmembrane and TPR repeat-containing protein 3 (Protein SMILE)TMTC3Q6ZXV51
Transmembrane anterior posterior transformation protein 1 homolog (Cytomegalovirus partial fusion receptor)TAPT1 CMVFRQ6NXT61
Transmembrane channel-like protein 1 (Transmembrane cochlear-expressed protein 1)TMC1Q8TDI81
Transmembrane gamma-carboxyglutamic acid protein 1 (Proline-rich gamma-carboxyglutamic acid protein 1) (Proline-rich Gla protein 1)PRRG1 PRGP1 TMG1O146681
Transmembrane gamma-carboxyglutamic acid protein 3 (Proline-rich gamma-carboxyglutamic acid protein 3) (Proline-rich Gla protein 3)PRRG3 PRGP3 TMG3Q9BZD71
Transmembrane gamma-carboxyglutamic acid protein 4 (Proline-rich gamma-carboxyglutamic acid protein 4) (Proline-rich Gla protein 4)PRRG4 PRGP4 TMG4Q9BZD61
Transmembrane protease serine 11B (EC 3.4.21.-) (Airway trypsin-like protease 5)TMPRSS11B HATL5Q86T261
Transmembrane protease serine 6 (EC 3.4.21.-) (Matriptase-2)TMPRSS6 UNQ354/PRO618Q8IU801
Transmembrane protein 104TMEM104Q8NE001
Transmembrane protein 105TMEM105Q8N8V81
Transmembrane protein 106ATMEM106AQ96A251
Transmembrane protein 106BTMEM106BQ9NUM41
Transmembrane protein 110TMEM110Q86TL21
Transmembrane protein 116TMEM116Q8NCL81
Transmembrane protein 121TMEM121Q9BTD31
Transmembrane protein 128TMEM128Q5BJH21
Transmembrane protein 130TMEM130 UNQ719/PRO1383Q8N3G91
Transmembrane protein 143TMEM143 UNQ5922/PRO19813Q96AN51
Transmembrane protein 144TMEM144Q7Z5S91
Transmembrane protein 150B (Transmembrane protein 224)TMEM150B TMEM224A6NC511
Transmembrane protein 156TMEM156Q8N6141
Transmembrane protein 170BTMEM170BQ5T4T11
Transmembrane protein 175TMEM175Q9BSA91
Transmembrane protein 177TMEM177Q53S581
Transmembrane protein 182TMEM182 UNQ6974/PRO21957Q6ZP801
Transmembrane protein 184C (Transmembrane protein 34)TMEM184C TMEM34 PRO1355Q9NVA41
Transmembrane protein 196TMEM196Q5HYL71
Transmembrane protein 200B (Transmembrane protein TTMA) (Two transmembrane domain-containing family member B)TMEM200B TTMBQ69YZ21
Transmembrane protein 206TMEM206 C1orf75Q9H8131
Transmembrane protein 215TMEM215Q68D421
Transmembrane protein 220TMEM220Q6QAJ81
Transmembrane protein 245 (Protein CG-2)TMEM245 C9orf5Q9H3301
Transmembrane protein 246TMEM246 C9orf125Q9BRR31
Transmembrane protein 248TMEM248 C7orf42Q9NWD81
Transmembrane protein 252TMEM252 C9orf71Q8N6L71
Transmembrane protein 257TMEM257 CXorf1O960021
Transmembrane protein 35TMEM35Q53FP21
Transmembrane protein 39ATMEM39AQ9NV641
Transmembrane protein 39BTMEM39BQ9GZU31
Transmembrane protein 43 (Protein LUMA)TMEM43 UNQ2564/PRO6244Q9BTV41
Transmembrane protein 44TMEM44Q2T9K01
Transmembrane protein 45BTMEM45BQ96B211
Transmembrane protein 47 (Brain cell membrane protein 1) (Transmembrane 4 superfamily member 10)TMEM47 BCMP1 TM4SF10Q9BQJ41
Transmembrane protein 53TMEM53Q6P2H81
Transmembrane protein 60TMEM60 C7orf35 DC32Q9H2L41
Transmembrane protein 64TMEM64Q6YI461
Transmembrane protein 65TMEM65Q6PI781
Transmembrane protein 89TMEM89A2RUT31
Transmembrane protein 95TMEM95 UNQ9390/PRO34281Q3KNT91
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