EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
HLA class I histocompatibility antigen, B-7 alpha chain (MHC class I antigen B*7)HLA-B HLABP018896
Homeobox protein Hox-C4 (Homeobox protein CP19) (Homeobox protein Hox-3E)HOXC4 HOX3EP090176
Host cell factor 1 (HCF) (HCF-1) (C1 factor) (CFF) (VCAF) (VP16 accessory protein) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6]HCFC1 HCF1 HFC1P516106
IgG receptor FcRn large subunit p51 (FcRn) (IgG Fc fragment receptor transporter alpha chain) (Neonatal Fc receptor)FCGRT FCRNP558996
Immediate early response 3-interacting protein 1IER3IP1 HSPC039Q9Y5U96
Immunoglobulin superfamily containing leucine-rich repeat protein 2 (Leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein)ISLR2 KIAA1465 LINX UNQ1885/PRO4329Q6UXK26
Immunoglobulin superfamily member 11 (IgSF11) (Brain and testis-specific immunoglobulin superfamily protein) (Bt-IGSF) (V-set and immunoglobulin domain-containing protein 3)IGSF11 BTIGSF CXADRL1 VSIG3Q5DX216
Importin subunit alphaKPNA2Q7Z7266
Importin subunit alpha-5 (Karyopherin subunit alpha-1) (Nucleoprotein interactor 1) (NPI-1) (RAG cohort protein 2) (SRP1-beta) [Cleaved into: Importin subunit alpha-5, N-terminally processed]KPNA1 RCH2P522946
Importin-8 (Imp8) (Ran-binding protein 8) (RanBP8)IPO8 RANBP8O153976
Inhibitor of Bruton tyrosine kinase (IBtk)IBTK BTKI KIAA1417Q9P2D06
Inhibitor of growth protein 1ING1Q9UK536
Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)CHUK IKKA TCF16O151116
Inner centromere proteinINCENPQ9NQS76
Inositol polyphosphate 5-phosphatase K (EC 3.1.3.56) (Skeletal muscle and kidney-enriched inositol phosphatase)INPP5K PPS SKIPQ9BT406
Inositol-tetrakisphosphate 1-kinase (EC 2.7.1.134) (Inositol 1,3,4-trisphosphate 5/6-kinase) (Inositol-triphosphate 5/6-kinase) (Ins(1,3,4)P(3) 5/6-kinase) (EC 2.7.1.159)ITPK1Q135726
Inositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase B) (IP3 3-kinase B) (IP3K B) (InsP 3-kinase B)ITPKBP279876
Integral membrane protein GPR137B (Transmembrane 7 superfamily member 1 protein)GPR137B TM7SF1O604786
Integrin alpha-V (Vitronectin receptor subunit alpha) (CD antigen CD51) [Cleaved into: Integrin alpha-V heavy chain; Integrin alpha-V light chain]ITGAV MSK8 VNRAP067566
Integrin beta-4 (GP150) (CD antigen CD104)ITGB4P161446
Interleukin-1 receptor antagonist protein (IL-1RN) (IL-1ra) (IRAP) (ICIL-1RA) (IL1 inhibitor) (Anakinra)IL1RN IL1F3 IL1RAP185106
Intracellular hyaluronan-binding protein 4 (IHABP-4) (IHABP4) (Ki-1/57 intracellular antigen)HABP4Q5JVS06
Intraflagellar transport protein 81 homolog (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1)IFT81 CDV1Q8WYA06
IQ domain-containing protein KIQCKQ8N0W56
Iron-sulfur cluster assembly 2 homolog, mitochondrial (HESB-like domain-containing protein 1)ISCA2 HBLD1Q86U286
Iroquois-class homeodomain protein IRX-3 (Homeodomain protein IRXB1) (Iroquois homeobox protein 3)IRX3 IRXB1P784156
Jun B proto-oncogene (cDNA, FLJ94337, Homo sapiens jun B proto-oncogene (JUNB), mRNA)JUNB hCG_172481Q5U0796
K2P6.1 potassium channel (Potassium channel, subfamily K, member 6) (cDNA, FLJ96744, Homo sapiens potassium channel, subfamily K, member 6 (KCNK6),mRNA)KCNK6 hCG_1785216B2RDS26
KAT8 regulatory NSL complex subunit 3 (NSL complex protein NSL3) (Non-specific lethal 3 homolog) (Serum inhibited-related protein) (Testis development protein PRTD)KANSL3 KIAA1310 NSL3 PRTD SI1Q9P2N66
Katanin p60 ATPase-containing subunit A-like 1 (Katanin p60 subunit A-like 1) (EC 3.6.4.3) (p60 katanin-like 1)KATNAL1Q9BW626
Kelch domain-containing protein 8BKLHDC8B FP17659Q8IXV76
Kelch-like protein 21KLHL21 KIAA0469Q9UJP46
Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)KRT19P087276
Keratin, type II cytoskeletal 72 (Cytokeratin-72) (CK-72) (Keratin-72) (K72) (Type II inner root sheath-specific keratin-K6irs2) (Type-II keratin Kb35)KRT72 K6IRS2 KB35 KRT6 KRT6IRS2Q14CN46
Keratin, type II cytoskeletal 80 (Cytokeratin-80) (CK-80) (Keratin-80) (K80) (Type-II keratin Kb20)KRT80 KB20Q6KB666
Keratin-associated protein 2-1 (High sulfur keratin-associated protein 2.1) (Keratin-associated protein 2.1)KRTAP2-1 KAP2.1 KRTAP2.1A KRTAP2.1BQ9BYU56
Keratin-associated protein 5-1 (Keratin, cuticle, ultrahigh sulphur 1-like) (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1)KRTAP5-1 KAP5.1 KRN1L KRTAP5.1Q6L8H46
Keratin-associated protein 5-7 (Keratin-associated protein 5-3) (Keratin-associated protein 5.3) (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7)KRTAP5-7 KAP5-7 KAP5.3 KRTAP5.3 KRTAP5.7Q6L8G86
Keratinocyte-associated transmembrane protein 2KCT2 C5orf15 HTGN29Q8NC546
KH domain-containing, RNA-binding, signal transduction-associated protein 3 (RNA-binding protein T-Star) (Sam68-like mammalian protein 2) (SLM-2) (Sam68-like phosphotyrosine protein)KHDRBS3 SALP SLM2O755256
Kynureninase (EC 3.7.1.3) (L-kynurenine hydrolase)KYNUQ167196
La-related protein 7 (La ribonucleoprotein domain family member 7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)LARP7 HDCMA18PQ4G0J36
Lamin-B receptor (Integral nuclear envelope inner membrane protein) (LMN2R)LBRQ147396
Laminin subunit alpha-5 (Laminin-10 subunit alpha) (Laminin-11 subunit alpha) (Laminin-15 subunit alpha)LAMA5 KIAA0533 KIAA1907O152306
Late cornified envelope protein 1F (Late envelope protein 6)LCE1F LEP6Q5T7546
Late cornified envelope protein 3E (Late envelope protein 17)LCE3E LEP17Q5T5B06
Leucine zipper protein 1LUZP1Q86V486
Leucine-rich repeat-containing protein 37A3LRRC37A3 KIAA0563O603096
Leukosialin (Galactoglycoprotein) (GALGP) (Leukocyte sialoglycoprotein) (Sialophorin) (CD antigen CD43)SPN CD43P161506
LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm)LIMA1 EPLIN SREBP3 PP624Q9UHB66
Lon protease homolog, mitochondrial (EC 3.4.21.-) (LONHs) (Lon protease-like protein) (LONP) (Mitochondrial ATP-dependent protease Lon) (Serine protease 15)LONP1 PRSS15P367766
Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 3) (LACS 3)ACSL3 ACS3 FACL3 LACS3O955736
Ly-6/neurotoxin-like protein 1 (Secreted Ly-6/uPAR domain-containing protein 2) (Secreted Ly-6/uPAR-related protein 2) (SLURP-2)LYNX1 SLURP2Q9BZG96
Lymphocyte adaptor protein variant (Fragment)0Q59H486
LYR motif-containing protein 2LYRM2Q9NU236
Lysine-specific demethylase 5B (EC 1.14.11.-) (Cancer/testis antigen 31) (CT31) (Histone demethylase JARID1B) (Jumonji/ARID domain-containing protein 1B) (PLU-1) (Retinoblastoma-binding protein 2 homolog 1) (RBP2-H1)KDM5B JARID1B PLU1 RBBP2H1Q9UGL16
Lysosome-associated membrane glycoprotein 1 (LAMP-1) (Lysosome-associated membrane protein 1) (CD107 antigen-like family member A) (CD antigen CD107a)LAMP1P112796
M-phase inducer phosphatase 2 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25B)CDC25B CDC25HU2P303056
Macrophage migration inhibitory factor (MIF) (EC 5.3.2.1) (Glycosylation-inhibiting factor) (GIF) (L-dopachrome isomerase) (L-dopachrome tautomerase) (EC 5.3.3.12) (Phenylpyruvate tautomerase)MIF GLIF MMIFP141746
Major facilitator superfamily domain-containing protein 3MFSD3Q96ES66
Mannose-6-phosphate isomerase (EC 5.3.1.8) (Phosphohexomutase) (Phosphomannose isomerase) (PMI)MPI PMI1P349496
Mannose-P-dolichol utilization defect 1 protein (Suppressor of Lec15 and Lec35 glycosylation mutation homolog) (SL15)MPDU1O753526
MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1)MKNK1 MNK1Q9BUB56
MAP7 domain-containing protein 1 (Arginine/proline-rich coiled-coil domain-containing protein 1) (Proline/arginine-rich coiled-coil domain-containing protein 1)MAP7D1 KIAA1187 PARCC1 RPRC1 PP2464Q3KQU36
Mas-related G-protein coupled receptor member E (G-protein coupled receptor 167)MRGPRE GPR167 MRGEQ86SM86
Matrix metalloproteinase-24 (MMP-24) (EC 3.4.24.-) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (MTMMP5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP) (MT5MMP) [Cleaved into: Processed matrix metalloproteinase-24]MMP24 MT5MMPQ9Y5R26
Max-interacting protein 1 (Max interactor 1) (Class C basic helix-loop-helix protein 11) (bHLHc11)MXI1 BHLHC11P505396
Mediator of RNA polymerase II transcription subunit 24 (Activator-recruited cofactor 100 kDa component) (ARC100) (Cofactor required for Sp1 transcriptional activation subunit 4) (CRSP complex subunit 4) (Mediator complex subunit 24) (Thyroid hormone receptor-associated protein 4) (Thyroid hormone receptor-associated protein complex 100 kDa component) (Trap100) (hTRAP100) (Vitamin D3 receptor-interacting protein complex 100 kDa component) (DRIP100)MED24 ARC100 CRSP4 DRIP100 KIAA0130 THRAP4 TRAP100O754486
Mediator of RNA polymerase II transcription subunit 26 (Activator-recruited cofactor 70 kDa component) (ARC70) (Cofactor required for Sp1 transcriptional activation subunit 7) (CRSP complex subunit 7) (Mediator complex subunit 26) (Transcriptional coactivator CRSP70)MED26 ARC70 CRSP7O954026
Meiosis arrest female protein 1 (Limkain-b1)KIAA0430 LKAP MARF1Q9Y4F36
Melanoma-associated antigen 6 (Cancer/testis antigen 1.6) (CT1.6) (MAGE-6 antigen) (MAGE3B antigen)MAGEA6 MAGE6P433606
Melanoma-associated antigen D2 (11B6) (Breast cancer-associated gene 1 protein) (BCG-1) (Hepatocellular carcinoma-associated protein JCL-1) (MAGE-D2 antigen)MAGED2 BCG1Q9UNF16
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (Atrophin-1-interacting protein 3) (AIP-3) (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Trinucleotide repeat-containing gene 19 protein) (WW domain-containing protein 3) (WWP3)MAGI1 AIP3 BAIAP1 BAP1 TNRC19Q96QZ76
Membrane-associated progesterone receptor component 1 (mPR)PGRMC1 HPR6.6 PGRMCO002646
Metal transporter CNNM2 (Ancient conserved domain-containing protein 2) (Cyclin-M2)CNNM2 ACDP2Q9H8M56
Metalloreductase STEAP1 (EC 1.16.1.-) (Six-transmembrane epithelial antigen of prostate 1)STEAP1 PRSS24 STEAPQ9UHE86
Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA)MT1A MT1SP047316
Metallothionein-1G (MT-1G) (Metallothionein-1K) (MT-1K) (Metallothionein-IG) (MT-IG)MT1G MT1K MT1MP136406
Methionine aminopeptidase 1 (MAP 1) (MetAP 1) (EC 3.4.11.18) (Peptidase M 1)METAP1 KIAA0094P535826
Methionine--tRNA ligase, cytoplasmic (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS)MARSP561926
Methionine-R-sulfoxide reductase B1 (MsrB1) (EC 1.8.4.-) (Selenoprotein X) (SelX)MSRB1 SEPX1 HSPC270Q9NZV66
Methyl-CpG-binding domain protein 3-like 2 (MBD3-like protein 2)MBD3L2Q8NHZ76
Methylglutaconyl-CoA hydratase, mitochondrial (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding protein/enoyl-CoA hydratase)AUHQ138256
Methyltransferase-like protein 5 (EC 2.1.1.-)METTL5 DC3 HSPC133Q9NRN96
Microtubule-associated protein 1S (MAP-1S) (BPY2-interacting protein 1) (Microtubule-associated protein 8) (Variable charge Y chromosome 2-interacting protein 1) (VCY2-interacting protein 1) (VCY2IP-1) [Cleaved into: MAP1S heavy chain; MAP1S light chain]MAP1S BPY2IP1 C19orf5 MAP8 VCY2IP1Q66K746
Microtubule-associated protein RP/EB family member 3 (EB1 protein family member 3) (EBF3) (End-binding protein 3) (EB3) (RP3)MAPRE3Q9UPY86
Microtubule-associated proteins 1A/1B light chain 3A (Autophagy-related protein LC3 A) (Autophagy-related ubiquitin-like modifier LC3 A) (MAP1 light chain 3-like protein 1) (MAP1A/MAP1B light chain 3 A) (MAP1A/MAP1B LC3 A) (Microtubule-associated protein 1 light chain 3 alpha)MAP1LC3AQ9H4926
Minor histocompatibility antigen H13 (EC 3.4.23.-) (Intramembrane protease 1) (IMP-1) (IMPAS-1) (hIMP1) (Presenilin-like protein 3) (Signal peptide peptidase)HM13 H13 IMP1 PSL3 SPP MSTP086Q8TCT96
Mitochondrial carnitine/acylcarnitine carrier protein (Carnitine/acylcarnitine translocase) (CAC) (Solute carrier family 25 member 20)SLC25A20 CAC CACTO437726
Mitochondrial fission regulator 1-likeMTFR1L FAM54B HYST1888 MSTP116Q9H0196
Mitochondrial import inner membrane translocase subunit Tim10 B (Fracture callus protein 1) (FxC1) (Mitochondrial import inner membrane translocase subunit Tim9 B) (TIMM10B) (Tim10b)TIMM10B FXC1 TIM9B TIMM9BQ9Y5J66
Mitochondrial import inner membrane translocase subunit TIM14 (DnaJ homolog subfamily C member 19)DNAJC19 TIM14 TIMM14Q96DA66
Mitochondrial import inner membrane translocase subunit Tim17-A (Inner membrane preprotein translocase Tim17a)TIMM17A MIMT17 TIM17 TIM17A TIMM17Q995956
Mitochondrial import inner membrane translocase subunit TIM44TIMM44 MIMT44 TIM44O436156
Mitochondrial import receptor subunit TOM34 (hTom34) (Translocase of outer membrane 34 kDa subunit)TOMM34 URCC3Q157856
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)RHOT2 ARHT2 C16orf39Q8IXI16
Mitochondrial ribonuclease P protein 1 (Mitochondrial RNase P protein 1) (EC 2.1.1.-) (HBV pre-S2 trans-regulated protein 2) (RNA (guanine-9-)-methyltransferase domain-containing protein 1) (Renal carcinoma antigen NY-REN-49) (tRNA methyltransferase 10 homolog C)TRMT10C MRPP1 RG9MTD1Q7L0Y36
Mitochondrial ribosome-associated GTPase 2 (GTP-binding protein 5) (Protein obg homolog 1) (ObgH1)MTG2 GTPBP5 OBGH1Q9H4K76
Mitoferrin-2 (Mitochondrial RNA-splicing protein 3/4 homolog) (MRS3/4) (hMRS3/4) (Mitochondrial iron transporter 2) (Solute carrier family 25 member 28)SLC25A28 MFRN2 NPD016Q96A466
Mitogen-activated protein kinase 13 (MAP kinase 13) (MAPK 13) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 delta) (MAP kinase p38 delta) (Stress-activated protein kinase 4)MAPK13 PRKM13 SAPK4O152646
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