EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Valine--tRNA ligase (EC 6.1.1.9) (Protein G7a) (Valyl-tRNA synthetase) (ValRS)VARS G7A VARS2P266406
Vasodilator-stimulated phosphoprotein (VASP)VASPP505526
Very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 3 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 3) (HACD3) (Butyrate-induced protein 1) (B-ind1) (hB-ind1) (Protein tyrosine phosphatase-like protein PTPLAD1) (Protein-tyrosine phosphatase-like A domain-containing protein 1)PTPLAD1 BIND1 HACD3Q9P0356
Vesicle-associated membrane protein 4 (VAMP-4)VAMP4O753796
Vesicle-associated membrane protein 5 (VAMP-5) (Myobrevin)VAMP5 HSPC191O951836
Vesicle-associated membrane protein 8 (VAMP-8) (Endobrevin) (EDB)VAMP8Q9BV406
Vesicle-associated membrane protein-associated protein A (VAMP-A) (VAMP-associated protein A) (VAP-A) (33 kDa VAMP-associated protein) (VAP-33)VAPA VAP33Q9P0L06
Vinculin (Metavinculin) (MV)VCLP182066
Voltage-dependent T-type calcium channel subunit alpha-1H (Low-voltage-activated calcium channel alpha1 3.2 subunit) (Voltage-gated calcium channel subunit alpha Cav3.2)CACNA1HO951806
WAS protein family homolog 1 (CXYorf1-like protein on chromosome 9) (Protein FAM39E)WASH1 FAM39EA8K0Z36
WASH complex subunit strumpellinKIAA0196Q127686
WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1) (Atg18 protein homolog) (WD40 repeat protein interacting with phosphoinositides of 49 kDa) (WIPI 49 kDa)WIPI1 WIPI49Q5MNZ96
WD repeat-containing protein 19WDR19 KIAA1638Q8NEZ36
WD repeat-containing protein mioMIOSQ9NXC56
WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif)WWTR1 TAZQ9GZV56
Zinc finger and SCAN domain-containing protein 2 (Zinc finger protein 29 homolog) (Zfp-29) (Zinc finger protein 854)ZSCAN2 ZFP29 ZNF854Q7Z7L96
Zinc finger CCCH domain-containing protein 15 (DRG family-regulatory protein 1) (Likely ortholog of mouse immediate early response erythropoietin 4)ZC3H15 DFRP1 LEREPO4 HSPC303 HT010 MSTP012 PP730Q8WU906
Zinc finger CCHC domain-containing protein 24ZCCHC24 C10orf56Q8N2G66
Zinc finger CCHC domain-containing protein 7ZCCHC7 HSPC086Q8N3Z66
Zinc finger FYVE domain-containing protein 21 (ZF21)ZFYVE21Q9BQ246
Zinc finger HIT domain-containing protein 3 (HNF-4a coactivator) (Thyroid hormone receptor interactor 3) (Thyroid receptor-interacting protein 3) (TR-interacting protein 3) (TRIP-3)ZNHIT3 TRIP3Q156496
Zinc finger matrin-type protein 2ZMAT2Q96NC06
Zinc finger protein 205 (Zinc finger protein 210)ZNF205 ZNF210O952016
Zinc finger protein 22 (Zinc finger protein KOX15) (Zinc finger protein Krox-26)ZNF22 KOX15 KROX26P170266
Zinc finger protein 384 (CAG repeat protein 1) (CAS-interacting zinc finger protein) (Nuclear matrix transcription factor 4) (Nuclear matrix protein 4) (Trinucleotide repeat-containing gene 1 protein)ZNF384 CAGH1 CIZ NMP4 TNRC1Q8TF686
Zinc finger protein 524ZNF524Q96C556
Zinc finger protein 680ZNF680Q8NEM16
Zinc finger protein 706ZNF706 HSPC038 PNAS-113Q9Y5V06
Zinc finger protein 791ZNF791Q3KP316
Zinc finger protein 91 (Zinc finger protein HPF7) (Zinc finger protein HTF10)ZNF91Q054816
Zinc finger protein-like 1 (Zinc finger protein MCG4)ZFPL1O951596
Zona pellucida sperm-binding protein 3 (Sperm receptor) (ZP3A/ZP3B) (Zona pellucida glycoprotein 3) (Zp-3) (Zona pellucida protein C) [Cleaved into: Processed zona pellucida sperm-binding protein 3]ZP3 ZP3A ZP3B ZPCP217546
Zyxin (Zyxin-2)ZYXQ159426
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 1) (1-AGP acyltransferase 1) (1-AGPAT 1) (Lysophosphatidic acid acyltransferase alpha) (LPAAT-alpha) (Protein G15)AGPAT1 G15Q999435
14 kDa phosphohistidine phosphatase (EC 3.1.3.-) (Phosphohistidine phosphatase 1) (Protein janus-A homolog)PHPT1 PHP14 CGI-202 HSPC141Q9NRX45
182 kDa tankyrase-1-binding proteinTNKS1BP1 KIAA1741 TAB182Q9C0C25
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial (cDNA FLJ55733, highly similar to 2-oxoisovalerate dehydrogenase alpha subunit, mitochondrial (EC 1.2.4.4))BCKDHAB4DP475
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDE1A) (BCKDH E1-alpha)BCKDHAP126945
26S protease regulatory subunit 8 (26S proteasome AAA-ATPase subunit RPT6) (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (Thyroid hormone receptor-interacting protein 1) (TRIP1) (p45/SUG)PSMC5 SUG1P621955
26S proteasome non-ATPase regulatory subunit 13 (26S proteasome regulatory subunit RPN9) (26S proteasome regulatory subunit S11) (26S proteasome regulatory subunit p40.5)PSMD13Q9UNM65
26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Protein 55.11) (Tumor necrosis factor type 1 receptor-associated protein 2)PSMD2 TRAP2Q132005
28S ribosomal protein S14, mitochondrial (MRP-S14) (S14mt)MRPS14O607835
28S ribosomal protein S27, mitochondrial (MRP-S27) (S27mt)MRPS27 KIAA0264Q925525
28S ribosomal protein S30, mitochondrial (MRP-S30) (S30mt) (Programmed cell death protein 9)MRPS30 PDCD9 BM-047Q9NP925
28S ribosomal protein S33, mitochondrial (MRP-S33) (S33mt)MRPS33 CGI-139 PTD003Q9Y2915
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EC 5.3.3.5) (Cholestenol Delta-isomerase) (Delta(8)-Delta(7) sterol isomerase) (D8-D7 sterol isomerase) (Emopamil-binding protein)EBPQ151255
3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) (EC 1.1.1.31)HIBADHP319375
39S ribosomal protein L46, mitochondrial (L46mt) (MRP-L46) (P2ECSL)MRPL46 C15orf4 LIECG2Q9H2W65
39S ribosomal protein L53, mitochondrial (L53mt) (MRP-L53)MRPL53Q96EL35
5-aminolevulinate synthase, erythroid-specific, mitochondrial (ALAS-E) (EC 2.3.1.37) (5-aminolevulinic acid synthase 2) (Delta-ALA synthase 2) (Delta-aminolevulinate synthase 2)ALAS2 ALASE ASBP225575
5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (5-OPase) (Pyroglutamase)OPLAHO148415
6-phosphofructokinase, liver type (EC 2.7.1.11) (Phosphofructo-1-kinase isozyme B) (PFK-B) (Phosphofructokinase 1) (Phosphohexokinase)PFKLP178585
6-phosphofructokinase, muscle type (EC 2.7.1.11) (Phosphofructo-1-kinase isozyme A) (PFK-A) (Phosphofructokinase-M) (Phosphofructokinase 1) (Phosphohexokinase)PFKM PFKXP082375
6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44)PGD PGDHP522095
6-pyruvoyl tetrahydrobiopterin synthase (PTP synthase) (PTPS) (EC 4.2.3.12)PTSQ033935
60S ribosomal protein L36a (60S ribosomal protein L44) (Cell growth-inhibiting gene 15 protein) (Cell migration-inducing gene 6 protein)RPL36A RPL44 GIG15 MIG6P838815
Abhydrolase domain-containing protein 4 (EC 3.1.1.-) (Alpha/beta-hydrolase 4) (Lyso-N-acylphosphatidylethanolamine lipase)ABHD4Q8TB405
Acetoacetyl-CoA synthetase (EC 6.2.1.16) (Acyl-CoA synthetase family member 1) (Protein sur-5 homolog)AACS ACSF1Q86V215
Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase)ACO2Q997985
Actin filament-associated protein 1 (110 kDa actin filament-associated protein) (AFAP-110)AFAP1 AFAPQ8N5565
Actin filament-associated protein 1-like 2 (AFAP1-like protein 2)AFAP1L2 KIAA1914 XB130Q8N4X55
Actin related protein 2/3 complex, subunit 2, 34kDa, isoform CRA_a (Putative uncharacterized protein ARPC2) (cDNA FLJ76076, highly similar to Homo sapiens actin related protein 2/3 complex, subunit 2, 34kDa (ARPC2), transcript variant 2, mRNA)ARPC2 hCG_16304Q53R195
Actin-binding LIM protein 3 (abLIM-3) (Actin-binding LIM protein family member 3)ABLIM3 KIAA0843 HMFN1661O949295
Actin-related protein 2/3 complex subunit 5-like protein (Arp2/3 complex 16 kDa subunit 2) (ARC16-2)ARPC5LQ9BPX55
Acyl carrier protein, mitochondrial (ACP) (CI-SDAP) (NADH-ubiquinone oxidoreductase 9.6 kDa subunit)NDUFAB1O145615
Acyl-coenzyme A thioesterase THEM4 (Acyl-CoA thioesterase THEM4) (EC 3.1.2.2) (Carboxyl-terminal modulator protein) (Thioesterase superfamily member 4)THEM4 CTMPQ5T1C65
Acylpyruvase FAHD1, mitochondrial (EC 3.7.1.5) (Fumarylacetoacetate hydrolase domain-containing protein 1) (YisK-like protein)FAHD1 C16orf36 YISKLQ6P5875
ADAMTS-like protein 5 (ADAMTSL5 protein)ADAMTSL5Q0VD775
Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)APC DP2.5P250545
ADP-ribosylation factor-like protein 6-interacting protein 4 (ARL-6-interacting protein 4) (Aip-4) (HSP-975) (HSVI-binding protein) (SR-15) (SRp25) (SR-25) (Splicing factor SRrp37)ARL6IP4Q66PJ35
ADP-ribosylation factor-like protein 8B (ADP-ribosylation factor-like protein 10C) (Novel small G protein indispensable for equal chromosome segregation 1)ARL8B ARL10C GIE1Q9NVJ25
AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31 protein) (Protein AF-5q31) (Major CDK9 elongation factor-associated protein)AFF4 AF5Q31 MCEF HSPC092Q9UHB75
Agouti related protein homolog (Mouse) (Agouti-related protein)AgRP AGRP hCG_28814C6SUN55
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)]AGRN AGRINO004685
Aldehyde dehydrogenase family 16 member A1ALDH16A1Q8IZ835
Alkaline phosphatase, placental-like (EC 3.1.3.1) (ALP-1) (Alkaline phosphatase Nagao isozyme) (Germ cell alkaline phosphatase) (GCAP) (Placental alkaline phosphatase-like) (PLAP-like)ALPPL2 ALPPLP106965
Alkaline phosphatase, tissue-nonspecific isozyme (AP-TNAP) (TNSALP) (EC 3.1.3.1) (Alkaline phosphatase liver/bone/kidney isozyme)ALPLP051865
Alpha-(1,3)-fucosyltransferase 6 (EC 2.4.1.65) (Fucosyltransferase 6) (Fucosyltransferase VI) (Fuc-TVI) (FucT-VI) (Galactoside 3-L-fucosyltransferase)FUT6 FCT3AP519935
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 7) (Spermatogenesis cell proliferation-related protein) (Spermatogenesis-associated protein 11)ALKBH7 ABH7 SPATA11 UNQ6002/PRO34564Q9BT305
Alpha-N-acetylglucosaminidase (EC 3.2.1.50) (N-acetyl-alpha-glucosaminidase) (NAG) [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form; Alpha-N-acetylglucosaminidase 77 kDa form]NAGLU UFHSD1P548025
Alpha-synuclein transcript variant 10 (Alpha-synuclein transcript variant 13) (Alpha-synuclein transcript variant 7)SNCAH6UYS55
Amelogenin, X isoformAMELX AMG AMGXQ992175
Amine oxidase [flavin-containing] A (EC 1.4.3.4) (Monoamine oxidase type A) (MAO-A)MAOAP213975
Aminopeptidase B (AP-B) (EC 3.4.11.6) (Arginine aminopeptidase) (Arginyl aminopeptidase)RNPEP APBQ9H4A45
Amphoterin-induced protein 1 (AMIGO-1) (Alivin-2)AMIGO1 ALI2 AMIGO KIAA1163Q86WK65
Amyloid beta A4 precursor protein-binding family B member 1 (Protein Fe65)APBB1 FE65 RIRO002135
Amyloid protein-binding protein 2 (Amyloid beta precursor protein-binding protein 2) (APP-BP2) (Protein interacting with APP tail 1)APPBP2 KIAA0228 PAT1Q926245
Anaphase-promoting complex subunit 4 (APC4) (Cyclosome subunit 4)ANAPC4 APC4Q9UJX55
Ancient ubiquitous protein 1AUP1Q9Y6795
Angio-associated migratory cell proteinAAMPQ136855
Angiogenin (EC 3.1.27.-) (Ribonuclease 5) (RNase 5)ANG RNASE5P039505
Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Novel retinal pigment epithelial cell protein) (Retinoic acid-induced protein 14)RAI14 KIAA1334 NORPEGQ9P0K75
Ankyrin repeat domain-containing protein 13A (Protein KE03)ANKRD13A ANKRD13Q8IZ075
Antigen peptide transporter 1 (APT1) (ATP-binding cassette sub-family B member 2) (Peptide supply factor 1) (Peptide transporter PSF1) (PSF-1) (Peptide transporter TAP1) (Peptide transporter involved in antigen processing 1) (Really interesting new gene 4 protein)TAP1 ABCB2 PSF1 RING4 Y3Q035185
AP-3 complex subunit sigma-2 (AP-3 complex subunit sigma-3B) (Adapter-related protein complex 3 subunit sigma-2) (Sigma-3B-adaptin) (Sigma3B-adaptin) (Sigma-adaptin 3b)AP3S2P597805
AP-4 complex accessory subunit tepsin (ENTH domain-containing protein 2) (Epsin for AP-4) (Tetra-epsin)ENTHD2 C17orf56Q96N215
AP-5 complex subunit zeta-1 (Adapter-related protein complex 5 zeta subunit) (Zeta5)AP5Z1 KIAA0415 SPG48O432995
Apelin (APJ endogenous ligand) [Cleaved into: Apelin-36; Apelin-31; Apelin-28; Apelin-13]APLN APELQ9ULZ15
Apolipoprotein A-I (Apo-AI) (ApoA-I) (Apolipoprotein A1) [Cleaved into: Truncated apolipoprotein A-I (Apolipoprotein A-I(1-242))]APOA1P026475
Apolipoprotein D (Apo-D) (ApoD)APODP050905
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