EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (13 kDa differentiation-associated protein) (Complex I-B17.2) (CI-B17.2) (CIB17.2) (NADH-ubiquinone oxidoreductase subunit B17.2)NDUFA12 DAP13Q9UI095
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (Complex I subunit B13) (Complex I-13kD-B) (CI-13kD-B) (NADH-ubiquinone oxidoreductase 13 kDa-B subunit)NDUFA5Q167185
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (Complex I-ESSS) (CI-ESSS) (NADH-ubiquinone oxidoreductase ESSS subunit) (Neuronal protein 17.3) (Np17.3) (p17.3)NDUFB11 UNQ111/PRO1064Q9NX145
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (Complex I-13kD-A) (CI-13kD-A) (NADH-ubiquinone oxidoreductase 13 kDa-A subunit)NDUFS6O753805
NADP-dependent malic enzyme (NADP-ME) (EC 1.1.1.40) (Malic enzyme 1)ME1P481635
NADP-dependent malic enzyme, mitochondrial (NADP-ME) (EC 1.1.1.40) (Malic enzyme 3)ME3Q167985
Nebulette (Actin-binding Z-disk protein)NEBL LNEBLO760415
NEDD8 ultimate buster 1 (Negative regulator of ubiquitin-like proteins 1) (Renal carcinoma antigen NY-REN-18)NUB1 NYREN18Q9Y5A75
Neudesin (Cell immortalization-related protein 2) (Neuron-derived neurotrophic factor) (Secreted protein of unknown function) (SPUF protein)NENF CIR2 SPUFQ9UMX55
Neuroblast differentiation-associated protein AHNAK (Desmoyokin)AHNAK PM227Q096665
Neuroguidin (EIF4E-binding protein)NGDN C14orf120Q8NEJ95
Neuron-specific vesicular protein calcyonCALY DRD1IPQ9NYX45
Neuronal growth regulator 1 (IgLON family member 4)NEGR1 IGLON4 UNQ2433/PRO4993Q7Z3B15
Neurotrophin receptor-interacting factor homolog (Zinc finger protein 274) (Zinc finger protein HFB101) (Zinc finger protein with KRAB and SCAN domains 19) (Zinc finger protein zfp2) (Zf2)ZNF274 ZKSCAN19 SP2114Q96GC65
Neutral alpha-glucosidase AB (EC 3.2.1.84) (Alpha-glucosidase 2) (Glucosidase II subunit alpha)GANAB G2AN KIAA0088Q146975
NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha) (Major histocompatibility complex enhancer-binding protein MAD3)NFKBIA IKBA MAD3 NFKBIP259635
NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkB-B) (IkB-beta) (IkappaBbeta) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9) (TRIP-9)NFKBIB IKBB TRIP9Q156535
NFATC2-interacting protein (45 kDa NF-AT-interacting protein) (45 kDa NFAT-interacting protein) (Nuclear factor of activated T-cells, cytoplasmic 2-interacting protein)NFATC2IP NIP45Q8NCF55
Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein)NIN KIAA1565Q8N4C65
Ninjurin-1 (Nerve injury-induced protein 1)NINJ1Q929825
Nitrogen permease regulator 2-like protein (NPR2-like protein) (Gene 21 protein) (G21 protein) (Tumor suppressor candidate 4)NPRL2 TUSC4Q8WTW45
NmrA-like family domain-containing protein 1NMRAL1 HSCARGQ9HBL85
Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)TYK2P295975
NTF2-related export protein 2 (Protein p15-2)NXT2 BM-025 DC9Q9NPJ85
NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5) (ARK5) (Omphalocele kinase 1)NUAK1 ARK5 KIAA0537 OMPHK1O602855
Nuclear autoantigenic sperm protein (NASP)NASPP493215
Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T-cell transcription factor NFAT3) (NF-AT3)NFATC4 NFAT3Q149345
Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1)NUFIP1Q9UHK05
Nuclear nucleic acid-binding protein C1D (hC1D)C1DQ139015
Nuclear pore complex protein Nup85 (85 kDa nucleoporin) (FROUNT) (Nucleoporin Nup75) (Nucleoporin Nup85) (Pericentrin-1)NUP85 NUP75 PCNT1Q9BW275
Nuclear pore complex protein Nup93 (93 kDa nucleoporin) (Nucleoporin Nup93)NUP93 KIAA0095Q8N1F75
Nuclear protein localization protein 4 homolog (Protein NPL4)NPLOC4 KIAA1499 NPL4Q8TAT65
Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1)NCOA7 ERAP140 ESNA1 Nbla00052 Nbla10993Q8NI085
Nucleolar complex protein 2 homolog (Protein NOC2 homolog) (NOC2-like protein) (Novel INHAT repressor)NOC2L NIRQ9Y3T95
Nucleolar complex protein 4 homolog (NOC4 protein homolog) (NOC4-like protein) (Nucleolar complex-associated protein 4-like protein)NOC4LQ9BVI45
Nucleolar protein 11NOL11 L14Q9H8H05
Nucleolar protein 12NOL12Q9UGY15
Nucleolar protein of 40 kDa (pNO40) (Pnn-interacting nucleolar protein) (Putative S1 RNA-binding domain protein) (PS1D protein) (Zinc finger CCHC domain-containing protein 17)ZCCHC17 PS1D HSPC243 HSPC251 LDC4Q9NP645
Nucleoside diphosphate kinase 3 (NDK 3) (NDP kinase 3) (EC 2.7.4.6) (DR-nm23) (Nucleoside diphosphate kinase C) (NDPKC) (nm23-H3)NME3Q132325
Nucleoside diphosphate-linked moiety X motif 6 (Nudix motif 6) (EC 3.6.1.-) (Antisense basic fibroblast growth factor) (Protein GFG)NUDT6 FGF2ASP533705
Nucleotide exchange factor SIL1 (BiP-associated protein) (BAP)SIL1 UNQ545/PRO836Q9H1735
Nucleus accumbens-associated protein 1 (NAC-1) (BTB/POZ domain-containing protein 14B)NACC1 BTBD14B NAC1Q96RE75
NudC domain-containing protein 3NUDCD3 KIAA1068Q8IVD95
O-acetyl-ADP-ribose deacetylase 1 (EC 3.5.1.-)OARD1 C6orf130Q9Y5305
Occludin/ELL domain-containing protein 1OCEL1Q9H6075
Oligophrenin-1OPHN1O608905
Orexin receptor type 1 (Ox-1-R) (Ox1-R) (Ox1R) (Hypocretin receptor type 1)HCRTR1O436135
Origin recognition complex subunit 5ORC5 ORC5LO439135
Ornithine decarboxylase (ODC) (EC 4.1.1.17)ODC1P119265
Ornithine decarboxylase antizyme 2 (AZ2) (ODC-Az 2)OAZ2O951905
Osteocalcin (Bone Gla protein) (BGP) (Gamma-carboxyglutamic acid-containing protein)BGLAPP028185
OTU domain-containing protein 4 (EC 3.4.19.12) (HIV-1-induced protein HIN-1)OTUD4 HIN1 KIAA1046Q018045
Oxidoreductase HTATIP2 (EC 1.1.1.-) (30 kDa HIV-1 TAT-interacting protein) (HIV-1 TAT-interactive protein 2)HTATIP2 CC3 TIP30Q9BUP35
p53 apoptosis effector related to PMP-22 (Keratinocyte-associated protein 1) (KCP-1) (P53-induced protein PIGPC1) (Transmembrane protein THW)PERP KCP1 KRTCAP1 PIGPC1 THWQ96FX85
p53-induced protein with a death domain (Leucine-rich repeat and death domain-containing protein)PIDD LRDDQ9HB755
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)SIN3AQ96ST35
Paired box protein Pax-3 (HuP2)PAX3 HUP2P237605
Paired box protein Pax-8PAX8Q067105
Palmitoyl-protein thioesterase 1 (PPT-1) (EC 3.1.2.22) (Palmitoyl-protein hydrolase 1)PPT1 PPTP508975
Pantothenate kinase 2, mitochondrial (hPanK2) (EC 2.7.1.33) (Pantothenic acid kinase 2)PANK2 C20orf48Q9BZ235
Paralemmin-1 (Paralemmin)PALM KIAA0270O757815
Paraplegin (EC 3.4.24.-) (Spastic paraplegia 7 protein)SPG7 CAR CMAR PGNQ9UQ905
Partner of Y14 and mago (Protein wibg homolog)WIBG PYMQ9BRP85
Patatin-like phospholipase domain-containing protein 2 (EC 3.1.1.3) (Adipose triglyceride lipase) (Calcium-independent phospholipase A2) (Desnutrin) (IPLA2-zeta) (Pigment epithelium-derived factor) (TTS2.2) (Transport-secretion protein 2) (TTS2)PNPLA2 ATGL FP17548Q96AD55
PAX3- and PAX7-binding protein 1 (GC-rich sequence DNA-binding factor 1)PAXBP1 C21orf66 GCFC GCFC1Q9Y5B65
PC-esterase domain-containing protein 1A (Protein FAM113A) (Sarcoma antigen NY-SAR-23)PCED1A C20orf81 FAM113AQ9H1Q75
PDZ and LIM domain protein 1 (C-terminal LIM domain protein 1) (Elfin) (LIM domain protein CLP-36)PDLIM1 CLIM1 CLP36O001515
PDZ and LIM domain protein 4 (LIM protein RIL) (Reversion-induced LIM protein)PDLIM4 RILP504795
Peptide chain release factor 1-like, mitochondrial (Mitochondrial translational release factor 1-like) (mtRF1a)MTRF1L MTRF1AQ9UGC75
Peptidyl-prolyl cis-trans isomerase C (PPIase C) (EC 5.2.1.8) (Cyclophilin C) (Rotamase C)PPIC CYPCP458775
Peptidyl-prolyl cis-trans isomerase CWC27 homolog (PPIase CWC27) (EC 5.2.1.8) (Antigen NY-CO-10) (Serologically defined colon cancer antigen 10)CWC27 SDCCAG10 UNQ438/PRO871Q6UX045
Peptidyl-prolyl cis-trans isomerase FKBP1B (PPIase FKBP1B) (EC 5.2.1.8) (12.6 kDa FK506-binding protein) (12.6 kDa FKBP) (FKBP-12.6) (FK506-binding protein 1B) (FKBP-1B) (Immunophilin FKBP12.6) (Rotamase) (h-FKBP-12)FKBP1B FKBP12.6 FKBP1L FKBP9 OTK4P681065
Peptidyl-prolyl cis-trans isomerase FKBP3 (PPIase FKBP3) (EC 5.2.1.8) (25 kDa FK506-binding protein) (25 kDa FKBP) (FKBP-25) (FK506-binding protein 3) (FKBP-3) (Immunophilin FKBP25) (Rapamycin-selective 25 kDa immunophilin) (Rotamase)FKBP3 FKBP25Q006885
Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (Androgen-regulated protein 6) (FF1 antigen) (FK506-binding protein 5) (FKBP-5) (FKBP54) (p54) (HSP90-binding immunophilin) (Rotamase)FKBP5 AIG6 FKBP51Q134515
Peroxisomal acyl-coenzyme A oxidase 2 (EC 1.17.99.3) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase) (Trihydroxycoprostanoyl-CoA oxidase) (THCA-CoA oxidase) (THCCox)ACOX2Q994245
Peroxisomal carnitine O-octanoyltransferase (COT) (EC 2.3.1.137)CROT COTQ9UKG95
Peroxisomal targeting signal 1 receptor (PTS1 receptor) (PTS1R) (PTS1-BP) (Peroxin-5) (Peroxisomal C-terminal targeting signal import receptor) (Peroxisome receptor 1)PEX5 PXR1P505425
Peroxisome proliferator-activated receptor gamma (PPAR-gamma) (Nuclear receptor subfamily 1 group C member 3)PPARG NR1C3P372315
PHD and RING finger domain-containing protein 1PHRF1 KIAA1542Q9P1Y65
PHD finger protein 11 (BRCA1 C-terminus-associated protein) (Renal carcinoma antigen NY-REN-34)PHF11 BCAPQ9UIL85
PHD finger protein 23 (PDH-containing protein JUNE-1)PHF23Q9BUL55
PHD finger protein 3PHF3 KIAA0244Q925765
Phenylalanine--tRNA ligase, mitochondrial (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase) (PheRS)FARS2 FARS1 HSPC320O953635
Phosducin-like protein (PHLP)PDCLQ133715
Phosphatidylinositide phosphatase SAC1 (EC 3.1.3.-) (Suppressor of actin mutations 1-like protein)SACM1L KIAA0851Q9NTJ55
Phosphatidylinositol 3-kinase catalytic subunit type 3 (PI3-kinase type 3) (PI3K type 3) (PtdIns-3-kinase type 3) (EC 2.7.1.137) (Phosphatidylinositol 3-kinase p100 subunit) (Phosphoinositide-3-kinase class 3) (hVps34)PIK3C3 VPS34Q8NEB95
Phosphatidylinositol 4-kinase alpha (PI4-kinase alpha) (PI4K-alpha) (PtdIns-4-kinase alpha) (EC 2.7.1.67)PI4KA PIK4 PIK4CAP423565
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (PI3K-C2-alpha) (PtdIns-3-kinase C2 subunit alpha) (EC 2.7.1.154) (Phosphoinositide 3-kinase-C2-alpha)PIK3C2AO004435
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A (EC 2.4.1.198) (GlcNAc-PI synthesis protein) (Phosphatidylinositol-glycan biosynthesis class A protein) (PIG-A)PIGAP372875
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y (Phosphatidylinositol-glycan biosynthesis class Y protein) (PIG-Y)PIGYQ3MUY25
Phosphofurin acidic cluster sorting protein 1 (PACS-1)PACS1 KIAA1175Q6VY075
Phosphofurin acidic cluster sorting protein 2 (PACS-2) (PACS1-like protein)PACS2 KIAA0602 PACS1LQ86VP35
Phosphomannomutase 1 (PMM 1) (EC 5.4.2.8) (PMMH-22)PMM1 PMMH22Q928715
Phosphopantothenate--cysteine ligase (EC 6.3.2.5) (Phosphopantothenoylcysteine synthetase) (PPC synthetase)PPCS COABQ9HAB85
Pikachurin (Agrin-like protein) (EGF-like, fibronectin type-III and laminin G-like domain-containing protein)EGFLAM AGRINL AGRNLQ63HQ25
Pituitary homeobox 1 (Hindlimb-expressed homeobox protein backfoot) (Homeobox protein PITX1) (Paired-like homeodomain transcription factor 1)PITX1 BFT PTX1P783375
Placenta growth factor (PlGF)PGF PGFL PLGFP497635
Plastin-1 (Intestine-specific plastin) (I-plastin)PLS1Q146515
Pleckstrin homology domain-containing family A member 1 (PH domain-containing family A member 1) (Tandem PH domain-containing protein 1) (TAPP-1)PLEKHA1 TAPP1Q9HB215
Pleckstrin homology domain-containing family M member 1 (PH domain-containing family M member 1) (162 kDa adapter protein) (AP162)PLEKHM1 KIAA0356Q9Y4G25
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