EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Pleckstrin homology-like domain family A member 3 (TDAG51/Ipl homolog 1)PHLDA3 TIH1Q9Y5J55
Pleiotropic regulator 1PLRG1O436605
PMAIP1 protein (Phorbol-12-myristate-13-acetate-induced protein 1)PMAIP1Q8N5895
Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor) (FUSE-binding protein-interacting repressor) (FBP-interacting repressor) (Ro-binding protein 1) (RoBP1) (Siah-binding protein 1) (Siah-BP1)PUF60 FIR ROBPI SIAHBP1Q9UHX15
Polyadenylate-binding protein 1-like 2 (RNA-binding motif protein 32) (RNA-binding protein 32)PABPC1L2A PABPC1L2 RBM32A; PABPC1L2B PABPC1L2 RBM32BQ5JQF85
Polyadenylate-binding protein 3 (PABP-3) (Poly(A)-binding protein 3) (Testis-specific poly(A)-binding protein)PABPC3 PABP3 PABPL3Q9H3615
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)PABPC4 APP1 PABP4Q133105
Polymerase delta-interacting protein 2 (38 kDa DNA polymerase delta interaction protein) (p38)POLDIP2 PDIP38 POLD4 HSPC017Q9Y2S75
Polyribonucleotide nucleotidyltransferase 1, mitochondrial (EC 2.7.7.8) (3'-5' RNA exonuclease OLD35) (PNPase old-35) (Polynucleotide phosphorylase 1) (PNPase 1) (Polynucleotide phosphorylase-like protein)PNPT1 PNPASEQ8TCS85
Porimin (Keratinocytes-associated transmembrane protein 3) (KCT-3) (Pro-oncosis receptor inducing membrane injury) (Transmembrane protein 123)TMEM123 KCT3 PSEC0111 UNQ641/PRO1271Q8N1315
Potassium channel subfamily K member 4 (TWIK-related arachidonic acid-stimulated potassium channel protein) (TRAAK) (Two pore potassium channel KT4.1) (Two pore K(+) channel KT4.1)KCNK4 TRAAKQ9NYG85
Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2)KCNG1Q9UIX45
Potassium voltage-gated channel subfamily H member 2 (Eag homolog) (Ether-a-go-go-related gene potassium channel 1) (ERG-1) (Eag-related protein 1) (Ether-a-go-go-related protein 1) (H-ERG) (hERG-1) (hERG1) (Voltage-gated potassium channel subunit Kv11.1)KCNH2 ERG ERG1 HERGQ128095
POU domain, class 3, transcription factor 1 (Octamer-binding protein 6) (Oct-6) (Octamer-binding transcription factor 6) (OTF-6) (POU domain transcription factor SCIP)POU3F1 OCT6 OTF6Q030525
PQ-loop repeat-containing protein 1PQLC1Q8N2U95
Pre-mRNA-processing factor 6 (Androgen receptor N-terminal domain-transactivating protein 1) (ANT-1) (PRP6 homolog) (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein)PRPF6 C20orf14O949065
Pre-mRNA-splicing factor ISY1 homologISY1 KIAA1160Q9ULR05
PRKC apoptosis WT1 regulator protein (Prostate apoptosis response 4 protein) (Par-4)PAWR PAR4Q96IZ05
PRKCA protein (Fragment)PRKCAQ7Z7275
PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein)PICK1 PRKCABPQ9NRD55
Probable 8-oxo-dGTP diphosphatase NUDT15 (8-oxo-dGTPase NUDT15) (EC 3.6.1.55) (7,8-dihydro-8-oxoguanine-triphosphatase NUDT15) (MutT homolog 2) (MTH2) (Nucleoside diphosphate-linked moiety X motif 15) (Nudix motif 15)NUDT15 MTH2Q9NV355
Probable ATP-dependent RNA helicase DDX41 (EC 3.6.4.13) (DEAD box protein 41) (DEAD box protein abstrakt homolog)DDX41 ABSQ9UJV95
Probable ATP-dependent RNA helicase DHX37 (EC 3.6.4.13) (DEAH box protein 37)DHX37 DDX37 KIAA1517Q8IY375
Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5)GPR152 PGR5Q8TDT25
Probable G-protein coupled receptor 153 (G-protein coupled receptor PGR1)GPR153 PGR1Q6NV755
Probable G-protein coupled receptor 25GPR25O001555
Probable glutathione peroxidase 8 (GPx-8) (GSHPx-8) (EC 1.11.1.9)GPX8 UNQ847/PRO1785Q8TED15
Probable palmitoyltransferase ZDHHC12 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 12) (DHHC-12) (Zinc finger protein 400)ZDHHC12 ZNF400 PSEC0008Q96GR45
Probable RNA-binding protein 23 (RNA-binding motif protein 23) (RNA-binding region-containing protein 4) (Splicing factor SF2)RBM23 RNPC4 PP239Q86U065
Probable U3 small nucleolar RNA-associated protein 11 (U3 snoRNA-associated protein 11) (UTP11-like protein)UTP11L CGI-94 HDCMB12PQ9Y3A25
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (EC 1.14.11.4) (Lysyl hydroxylase 1) (LH1)PLOD1 LLH PLODQ028095
Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of non-genomic activity of estrogen receptor) (Transcription factor HMX3)PELP1 HMX3 MNARQ8IZL85
Proline-rich AKT1 substrate 1 (40 kDa proline-rich AKT substrate)AKT1S1 PRAS40Q96B365
Proline-rich protein 14PRR14Q9BWN15
Proteasome-associated protein ECM29 homologKIAA0368J3KN165
Protection of telomeres protein 1 (hPot1) (POT1-like telomere end-binding protein)POT1Q9NUX55
Protein AAR2 homolog (AAR2 splicing factor homolog)AAR2 C20orf4 CGI-23 PRO0225Q9Y3125
Protein AF1qMLLT11 AF1QQ130155
Protein argonaute-2 (Argonaute2) (hAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (PAZ Piwi domain protein) (PPD) (Protein slicer)AGO2 EIF2C2Q9UKV85
Protein ARV1 (hARV1)ARV1 HT035Q9H2C25
Protein BEX1 (Brain-expressed X-linked protein 1)BEX1Q9HBH75
Protein bicaudal D homolog 2 (Bic-D 2)BICD2 KIAA0699Q8TD165
Protein Bop (BH3-only protein)BOP C22orf29Q7L3V25
Protein C8orf37C8orf37Q96NL85
Protein capicua homologCIC KIAA0306Q96RK05
Protein CBFA2T3 (MTG8-related protein 2) (Myeloid translocation gene on chromosome 16 protein) (hMTG16) (Zinc finger MYND domain-containing protein 4)CBFA2T3 MTG16 MTGR2 ZMYND4O750815
Protein CLEC16ACLEC16A KIAA0350Q2KHT35
Protein CREG1 (Cellular repressor of E1A-stimulated genes 1)CREG1 CREG UNQ727/PRO1409O756295
Protein dpy-30 homolog (Dpy-30-like protein) (Dpy-30L)DPY30Q9C0055
Protein ENL (YEATS domain-containing protein 1)MLLT1 ENL LTG19 YEATS1Q031115
Protein FAM102A (Early estrogen-induced gene 1 protein)FAM102A C9orf132 EEIG1Q5T9C25
Protein FAM124AFAM124AQ86V425
Protein FAM131AFAM131A C3orf40 UNQ715/PRO1378Q6UXB05
Protein FAM131BFAM131B KIAA0773Q86XD55
Protein FAM133BFAM133BQ5BKY95
Protein FAM162A (E2-induced gene 5 protein) (Growth and transformation-dependent protein) (HGTD-P)FAM162A C3orf28 E2IG5 DC16 FWP001Q96A265
Protein FAM178AFAM178A C10orf6Q8IX215
Protein FAM178BFAM178B HSPC234Q8IXR55
Protein FAM210BFAM210B C20orf108 PSEC0265Q96KR65
Protein FAM219BFAM219B C15orf17Q5XKK75
Protein FAM222AFAM222A C12orf34Q5U5X85
Protein FAM46A (HBV X-transactivated gene 11 protein) (HBV XAg-transactivated protein 11)FAM46A C6orf37 XTP11Q96IP45
Protein FAM53CFAM53C C5orf6Q9NYF35
Protein FAM60A (Tera protein homolog)FAM60A C12orf14 L4Q9NP505
Protein FAM71E1FAM71E1Q6IPT25
Protein FAM84B (Breast cancer membrane protein 101) (Protein NSE2)FAM84B BCMP101 NSE2Q96KN15
Protein FAM86C1 (Protein FAM86C)FAM86C1 FAM86CQ9NVL15
Protein GUCD1 (Guanylyl cyclase domain-containing protein 1) (Protein LLN4)GUCD1 C22orf13 LLN4Q96NT35
Protein HEXIM1 (Cardiac lineage protein 1) (Estrogen down-regulated gene 1 protein) (Hexamethylene bis-acetamide-inducible protein 1) (Menage a quatre protein 1)HEXIM1 CLP1 EDG1 HIS1 MAQ1O949925
Protein HikeshiC11orf73 HSPC138 HSPC179 HSPC248Q53FT35
Protein Jade-1 (PHD finger protein 17)PHF17 JADE1 KIAA1807Q6IE815
Protein kish-A (Transmembrane protein 167) (Transmembrane protein 167A)TMEM167A TMEM167Q8TBQ95
Protein lin-9 homolog (HuLin-9) (hLin-9) (Beta subunit-associated regulator of apoptosis) (TUDOR gene similar protein) (Type I interferon receptor beta chain-associated protein) (pRB-associated protein)LIN9 BARA TGSQ5TKA15
Protein LMBR1L (Limb region 1 protein homolog-like) (Lipocalin-1-interacting membrane receptor) (Lipocalin-interacting membrane receptor)LMBR1L KIAA1174 LIMR UNQ458/PRO783Q6UX015
Protein MAK16 homolog (NNP78) (Protein RBM13)MAK16 RBM13Q9BXY05
Protein N-terminal glutamine amidohydrolase (EC 3.5.1.-) (Protein NH2-terminal glutamine deamidase) (N-terminal Gln amidase) (Nt(Q)-amidase) (WDYHV motif-containing protein 1)WDYHV1 C8orf32 NTAQ1Q96HA85
Protein NRDE2 homologNRDE2 C14orf102Q9H7Z35
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) (UDP-GlcNAc:alpha-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.2) (GnT I.2)POMGNT1 MGAT1.2 UNQ746/PRO1475Q8WZA15
Protein p13 MTCP-1 (p13MTCP1) (Mature T-cell proliferation-1 type B1) (MTCP-1 type B1)MTCP1 C6.1BP562785
Protein phosphatase 1 regulatory subunit 1A (Protein phosphatase inhibitor 1) (I-1) (IPP-1)PPP1R1A IPP1Q135225
Protein PRR14L (Proline rich 14-like protein)PRR14L C22orf30Q5THK15
Protein PRRC1 (Proline-rich and coiled-coil-containing protein 1)PRRC1Q96M275
Protein S100-P (Migration-inducing gene 9 protein) (MIG9) (Protein S100-E) (S100 calcium-binding protein P)S100P S100EP258155
Protein SCO2 homolog, mitochondrialSCO2O438195
Protein SDE2 homologSDE2 C1orf55Q6IQ495
Protein shisa-4 (Transmembrane protein 58)SHISA4 C1orf40 TMEM58 UNQ583/PRO1153Q96DD75
Protein spinster homolog 1 (HSpin1) (Spinster-like protein 1)SPNS1 SPIN1 PP20300Q9H2V75
Protein transport protein Sec61 subunit alpha isoform 1 (Sec61 alpha-1)SEC61A1 SEC61AP616195
Protein YIPF6 (YIP1 family member 6)YIPF6Q96EC85
Protein yippee-like 2YPEL2 FKSG4Q96QA65
Protein-L-isoaspartate O-methyltransferase domain-containing protein 2PCMTD2 C20orf36Q9NV795
Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)PTK2B FAK2 PYK2 RAFTKQ142895
Proteolipid protein 2 (Differentiation-dependent protein A4) (Intestinal membrane A4 protein)PLP2 A4Q049415
Protoheme IX farnesyltransferase, mitochondrial (EC 2.5.1.-) (Heme O synthase)COX10Q128875
PTB domain-containing engulfment adapter protein 1 (Cell death protein 6 homolog) (PTB domain adapter protein CED-6) (Protein GULP)GULP1 CED6 GULPQ9UBP95
Pterin-4-alpha-carbinolamine dehydratase (PHS) (EC 4.2.1.96) (4-alpha-hydroxy-tetrahydropterin dehydratase) (Dimerization cofactor of hepatocyte nuclear factor 1-alpha) (DCoH) (Dimerization cofactor of HNF1) (Phenylalanine hydroxylase-stimulating protein) (Pterin carbinolamine dehydratase) (PCD)PCBD1 DCOH PCBDP614575
Pulmonary surfactant-associated protein B (SP-B) (18 kDa pulmonary-surfactant protein) (6 kDa protein) (Pulmonary surfactant-associated proteolipid SPL(Phe))SFTPB SFTP3P079885
Putative ATP-dependent RNA helicase DHX33 (EC 3.6.4.13) (DEAH box protein 33)DHX33 DDX33Q9H6R05
Putative deoxyribonuclease TATDN2 (EC 3.1.21.-)TATDN2 KIAA0218Q930755
Putative E3 ubiquitin-protein ligase UBR7 (EC 6.3.2.-) (N-recognin-7)UBR7 C14orf130Q8N8065
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