EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Putative FAM120A opposite strand proteinFAM120AOS C9orf10OSQ5T0365
Putative golgin subfamily A member 6BGOLGA6B GOLGAA6NDN35
Putative helicase MOV-10 (EC 3.6.4.13) (Moloney leukemia virus 10 protein)MOV10 KIAA1631Q9HCE15
Putative hydrolase RBBP9 (EC 3.-.-.-) (B5T-overexpressed gene protein) (Protein BOG) (Retinoblastoma-binding protein 10) (RBBP-10) (Retinoblastoma-binding protein 9) (RBBP-9)RBBP9 BOG RBBP10O758845
Putative oxidoreductase GLYR1 (EC 1.-.-.-) (3-hydroxyisobutyrate dehydrogenase-like protein) (Cytokine-like nuclear factor N-PAC) (Glyoxylate reductase 1 homolog) (Nuclear protein NP60) (Nuclear protein of 60 kDa)GLYR1 HIBDL NP60Q49A265
Putative Polycomb group protein ASXL2 (Additional sex combs-like protein 2)ASXL2 ASXH2 KIAA1685Q76L835
Putative ribosomal RNA methyltransferase NOP2 (EC 2.1.1.-) (Nucleolar protein 1) (Nucleolar protein 2 homolog) (Proliferating-cell nucleolar antigen p120) (Proliferation-associated nucleolar protein p120)NOP2 NOL1P460875
Putative RNA-binding protein 15B (One-twenty two protein 3) (HuOTT3) (RNA-binding motif protein 15B)RBM15B OTT3Q8NDT25
Putative sodium-coupled neutral amino acid transporter 7 (Solute carrier family 38 member 7)SLC38A7 SNAT7Q9NVC35
Putative uncharacterized protein (Fragment)0Q8N4Y15
Putative uncharacterized protein DKFZp434N101 (Fragment)DKFZp434N101Q9UFY15
Putative uncharacterized protein DKFZp761H172DKFZp761H172Q9NSS65
Pyridoxine-5'-phosphate oxidase (EC 1.4.3.5) (Pyridoxamine-phosphate oxidase)PNPOQ9NVS95
R3H domain-containing protein 1R3HDM1 KIAA0029 R3HDMQ150325
Rab-like protein 3RABL3Q5HYI85
Rab-like protein 6 (GTP-binding protein Parf) (Partner of ARF) (Rab-like protein 1) (RBEL1)RABL6 C9orf86 PARFQ3YEC75
Rab11 family-interacting protein 5 (Rab11-FIP5) (Gamma-SNAP-associated factor 1) (Gaf-1) (Phosphoprotein pp75) (Rab11-interacting protein Rip11)RAB11FIP5 GAF1 KIAA0857 RIP11Q9BXF65
Rabenosyn-5 (110 kDa protein) (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20)ZFYVE20Q9H1K05
RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase B gamma) (PKB gamma) (RAC-PK-gamma) (STK-2)AKT3 PKBGQ9Y2435
RAD50 protein (Fragment)RAD50A5D6Y35
Radial spoke head protein 3 homolog (Radial spoke head-like protein 2)RSPH3 RSHL2 RSP3Q86UC25
Ragulator complex protein LAMTOR2 (Endosomal adaptor protein p14) (Late endosomal/lysosomal Mp1-interacting protein) (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2) (Mitogen-activated protein-binding protein-interacting protein) (MAPBP-interacting protein) (Roadblock domain-containing protein 3)LAMTOR2 MAPBPIP ROBLD3 HSPC003Q9Y2Q55
Ral guanine nucleotide dissociation stimulator (RalGDS) (Ral guanine nucleotide exchange factor) (RalGEF)RALGDS KIAA1308 RGFQ129675
Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1)RGL1 KIAA0959 RGLQ9NZL65
Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like 2) (RalGDS-like factor) (Ras-associated protein RAB2L)RGL2 RAB2LO152115
Ran-binding protein 10 (RanBP10)RANBP10 KIAA1464Q6VN205
Ran-specific GTPase-activating protein (Ran-binding protein 1) (RanBP1)RANBP1P434875
Rap1 GTPase-GDP dissociation stimulator 1 (Exchange factor smgGDS) (SMG GDS protein) (SMG P21 stimulatory GDP/GTP exchange protein)RAP1GDS1P523065
Ras GTPase-activating protein nGAP (RAS protein activator-like 2)RASAL2 NGAPQ9UJF25
Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)RAC2P151535
Ras-related GTP-binding protein C (Rag C) (RagC) (GTPase-interacting protein 2) (TIB929)RRAGCQ9HB905
Ras-related protein Rab-28RAB28P511575
Ras-related protein Ral-ARALA RALP112335
Ras-related protein Rap-1b (GTP-binding protein smg p21B)RAP1B OK/SW-cl.11P612245
Receptor expression-enhancing protein 5 (Polyposis locus protein 1) (Protein TB2)REEP5 C5orf18 DP1 TB2Q007655
Receptor expression-enhancing protein 6 (Polyposis locus protein 1-like 1)REEP6 C19orf32 DP1L1Q96HR95
Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR)PTPRF LARP105865
Regulator of G-protein signaling 12 (RGS12)RGS12O149245
Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP)RGS19 GAIP GNAI3IPP497955
Replication factor C subunit 1 (Activator 1 140 kDa subunit) (A1 140 kDa subunit) (Activator 1 large subunit) (Activator 1 subunit 1) (DNA-binding protein PO-GA) (Replication factor C 140 kDa subunit) (RF-C 140 kDa subunit) (RFC140) (Replication factor C large subunit)RFC1 RFC140P352515
Replication factor C subunit 3 (Activator 1 38 kDa subunit) (A1 38 kDa subunit) (Activator 1 subunit 3) (Replication factor C 38 kDa subunit) (RF-C 38 kDa subunit) (RFC38)RFC3P409385
Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)RPA2 REPA2 RPA32 RPA34P159275
RET proteinRETQ9BTX65
Retinitis pigmentosa 9 protein (Pim-1-associated protein) (PAP-1)RP9Q8TA865
Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3)RBBP5 RBQ3Q152915
Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (p130) (Retinoblastoma-related protein 2) (RBR-2) (pRb2)RBL2 RB2Q089995
Retinoic acid receptor responder protein 3 (EC 3.1.1.-) (HRAS-like suppressor 4) (HRSL4) (RAR-responsive protein TIG3) (Retinoid-inducible gene 1 protein) (Tazarotene-induced gene 3 protein)RARRES3 RIG1 TIG3Q9UL195
Retinol-binding protein 5 (Cellular retinol-binding protein III) (CRBP-III) (HRBPiso)RBP5P829805
Rho GTPase-activating protein 18 (MacGAP) (Rho-type GTPase-activating protein 18)ARHGAP18Q8N3925
Rho GTPase-activating protein 8 (Rho-type GTPase-activating protein 8)ARHGAP8P852985
Rho guanine nucleotide exchange factor 10ARHGEF10 KIAA0294O150135
Rho guanine nucleotide exchange factor 17 (164 kDa Rho-specific guanine-nucleotide exchange factor) (p164-RhoGEF) (p164RhoGEF) (Tumor endothelial marker 4)ARHGEF17 KIAA0337 TEM4Q96PE25
Rho guanine nucleotide exchange factor 3 (Exchange factor found in platelets and leukemic and neuronal tissues) (XPLN)ARHGEF3Q9NR815
Rho-related GTP-binding protein RhoGRHOG ARHGP840955
Rhodopsin (Opsin-2)RHO OPN2P081005
Rhombotin-2 (Cysteine-rich protein TTG-2) (LIM domain only protein 2) (LMO-2) (T-cell translocation protein 2)LMO2 RBTN2 RBTNL1 RHOM2 TTG2P257915
Riboflavin kinase (EC 2.7.1.26) (ATP:riboflavin 5'-phosphotransferase) (Flavokinase)RFKQ969G65
Ribonuclease H2 subunit B (RNase H2 subunit B) (Aicardi-Goutieres syndrome 2 protein) (AGS2) (Deleted in lymphocytic leukemia 8) (Ribonuclease HI subunit B)RNASEH2B DLEU8Q5TBB15
Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL)RPS6KA5 MSK1O755825
Ribosome-binding protein 1 (180 kDa ribosome receptor homolog) (RRp) (ES/130-related protein) (Ribosome receptor protein)RRBP1 KIAA1398Q9P2E95
Ribulose-phosphate 3-epimerase (EC 5.1.3.1) (Ribulose-5-phosphate-3-epimerase)RPE HUSSY-17Q96AT95
RING finger protein unkempt homolog (Zinc finger CCCH domain-containing protein 5)UNK KIAA1753 ZC3H5 ZC3HDC5Q9C0B05
RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (Prevents mitotic catastrophe 2 protein homolog) (hPMC2)REXO4 PMC2 XPMC2HQ9GZR25
RNA pseudouridylate synthase domain-containing protein 4RPUSD4Q96CM35
RNMT-activating mini protein (RAM) (Protein FAM103A1)FAM103A1 C15orf18Q9BTL35
RRP15-like protein (Ribosomal RNA-processing protein 15)RRP15 KIAA0507 CGI-115Q9Y3B95
Runt-related transcription factor 1 (Acute myeloid leukemia 1 protein) (Core-binding factor subunit alpha-2) (CBF-alpha-2) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEA2-alpha B) (PEBP2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit)RUNX1 AML1 CBFA2Q011965
S-adenosylmethionine mitochondrial carrier protein (Mitochondrial S-adenosylmethionine transporter) (Solute carrier family 25 member 26)SLC25A26 SAMCQ70HW35
S-methylmethionine--homocysteine S-methyltransferase BHMT2 (SMM-hcy methyltransferase) (EC 2.1.1.10) (Betaine--homocysteine S-methyltransferase 2)BHMT2Q9H2M35
Saccharopine dehydrogenase-like oxidoreductase (EC 1.-.-.-)SCCPDH CGI-49Q8NBX05
Secernin-1SCRN1 KIAA0193Q127655
Securin (Esp1-associated protein) (Pituitary tumor-transforming gene 1 protein) (Tumor-transforming protein 1) (hPTTG)PTTG1 EAP1 PTTG TUTR1O959975
Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3)DVL3 KIAA0208Q929975
Selenocysteine insertion sequence-binding protein 2 (SECIS-binding protein 2)SECISBP2 SBP2Q96T215
Selenocysteine insertion sequence-binding protein 2-like (SECIS-binding protein 2-like)SECISBP2L KIAA0256Q930735
Semaphorin-6A (Semaphorin VIA) (Sema VIA) (Semaphorin-6A-1) (SEMA6A-1)SEMA6A KIAA1368 SEMAQQ9H2E65
Serine hydroxymethyltransferase (EC 2.1.2.1) (Fragment)SHMT2Q5BJF55
Serine hydroxymethyltransferase, mitochondrial (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase)SHMT2P348975
Serine palmitoyltransferase 1 (EC 2.3.1.50) (Long chain base biosynthesis protein 1) (LCB 1) (Serine-palmitoyl-CoA transferase 1) (SPT 1) (SPT1)SPTLC1 LCB1O152695
Serine palmitoyltransferase small subunit A (Small subunit of serine palmitoyltransferase A) (ssSPTa)SPTSSA C14orf147 SSSPTAQ969W05
Serine protease 27 (EC 3.4.21.-) (Marapsin) (Pancreasin)PRSS27 MPN UNQ1884/PRO4327Q9BQR35
Serine protease 33 (EC 3.4.21.-) (Serine protease EOS)PRSS33Q8NF865
Serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)SARS SERSP495915
Serine--tRNA ligase, mitochondrial (EC 6.1.1.11) (SerRSmt) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)SARS2 SARSMQ9NP815
Serine/threonine-protein kinase 19 (EC 2.7.11.1) (Protein G11) (Protein RP1)STK19 G11 RP1P498425
Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)STK25 SOK1 YSK1O005065
Serine/threonine-protein kinase 40 (EC 2.7.11.1) (SINK-homologous serine/threonine-protein kinase) (Sugen kinase 495) (SgK495)STK40 SGK495 SHIKQ8N2I95
Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2)PKN2 PRK2 PRKCL2Q165135
Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (Never in mitosis A-related kinase 6) (NimA-related protein kinase 6) (Protein kinase SID6-1512)NEK6Q9HC985
Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) (PAK-1) (p65-PAK)PAK1Q131535
Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein kinase SNF1-like kinase 1) (Serine/threonine-protein kinase SNF1LK)SIK1 SIK SNF1LKP570595
Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1) (LKB1) (hLKB1) (Renal carcinoma antigen NY-REN-19)STK11 LKB1 PJSQ158315
Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Kinase from chicken homolog C) (hKFC-C) (Prostate-derived sterile 20-like kinase 1) (PSK-1) (PSK1) (Prostate-derived STE20-like kinase 1) (Thousand and one amino acid protein kinase 2)TAOK2 KIAA0881 MAP3K17 PSK PSK1 UNQ2971/PRO7431Q9UL545
Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) (hIRE1p) (Ire1-alpha) (IRE1a) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]ERN1 IRE1O754605
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform (PP2A subunit B isoform B55-beta) (PP2A subunit B isoform PR55-beta) (PP2A subunit B isoform R2-beta) (PP2A subunit B isoform beta)PPP2R2BQ000055
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PP2A subunit B isoform B55-delta) (PP2A subunit B isoform PR55-delta) (PP2A subunit B isoform R2-delta) (PP2A subunit B isoform delta)PPP2R2D KIAA1541Q66LE65
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A subunit A isoform PR65-beta) (PP2A subunit A isoform R1-beta)PPP2R1BP301545
Serine/threonine-protein phosphatase 6 regulatory subunit 3 (SAPS domain family member 3) (Sporulation-induced transcript 4-associated protein SAPL)PPP6R3 C11orf23 KIAA1558 PP6R3 SAPL SAPS3Q5H9R75
Serine/threonine-protein phosphatase PGAM5, mitochondrial (EC 3.1.3.16) (Bcl-XL-binding protein v68) (Phosphoglycerate mutase family member 5)PGAM5Q96HS15
SET-binding protein (SEB)SETBP1 KIAA0437Q9Y6X05
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