EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Transcription initiation factor TFIID subunit 4 (RNA polymerase II TBP-associated factor subunit C) (TBP-associated factor 4) (Transcription initiation factor TFIID 130 kDa subunit) (TAF(II)130) (TAFII-130) (TAFII130) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135)TAF4 TAF2C TAF2C1 TAF4A TAFII130 TAFII135O002685
Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33)ZBTB33 KAISO ZNF348Q86T245
Transcriptional repressor CTCF (11-zinc finger protein) (CCCTC-binding factor) (CTCFL paralog)CTCFP497115
Transducin-like enhancer protein 1 (E(Sp1) homolog) (Enhancer of split groucho-like protein 1) (ESG1)TLE1Q047245
Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog)TRRAP PAF400Q9Y4A55
Transforming growth factor beta-1-induced transcript 1 protein (Androgen receptor coactivator 55 kDa protein) (Androgen receptor-associated protein of 55 kDa) (Hydrogen peroxide-inducible clone 5 protein) (Hic-5)TGFB1I1 ARA55O432945
Translation initiation factor IF-2, mitochondrial (IF-2(Mt)) (IF-2Mt) (IF2(mt))MTIF2P461995
Translational activator GCN1 (HsGCN1) (GCN1-like protein 1)GCN1L1 KIAA0219Q926165
Transmembrane emp24 domain-containing protein 9 (GMP25) (Glycoprotein 25L2) (p24 family protein alpha-2) (p24alpha2) (p25)TMED9 GP25L2Q9BVK65
Transmembrane prostate androgen-induced protein (Solid tumor-associated 1 protein)PMEPA1 STAG1 TMEPAIQ969W95
Transmembrane protein 109 (Mitsugumin-23) (Mg23)TMEM109Q9BVC65
Transmembrane protein 138TMEM138 HSPC196 HSPC198Q9NPI05
Transmembrane protein 178ATMEM178A TMEM178 PSEC0131 UNQ5926/PRO19820Q8NBL35
Transmembrane protein 189TMEM189 KUAA5PLL75
Transmembrane protein 203TMEM203Q969S65
Transmembrane protein 205TMEM205 UNQ501/PRO1018Q6UW685
Transmembrane protein 208TMEM208 HSPC171Q9BTX35
Transmembrane protein 222TMEM222 C1orf160Q9H0R35
Transmembrane protein 223TMEM223A0PJW65
Transmembrane protein 261TMEM261 C9orf123Q96GE95
Transmembrane protein 5TMEM5Q9Y2B15
Transmembrane protein 51TMEM51 C1orf72Q9NW975
Transmembrane protein 63ATMEM63A KIAA0489 KIAA0792O948865
Transmembrane protein 8B (Nasopharyngeal carcinoma-associated gene 6 protein) (Protein NAG-5) (Protein NGX6)TMEM8B C9orf127 NGX6A6NDV45
Transmembrane protein with metallophosphoesterase domain (EC 3.1.-.-)TMPPEQ6ZT215
Tribbles homolog 1 (TRB-1) (G-protein-coupled receptor-induced gene 2 protein) (GIG-2) (SKIP1)TRIB1 C8FW GIG2 TRB1Q96RU85
Tricarboxylate transport protein, mitochondrial (Citrate transport protein) (CTP) (Solute carrier family 25 member 1) (Tricarboxylate carrier protein)SLC25A1 SLC20A3P530075
Trinucleotide repeat-containing gene 6B proteinTNRC6B KIAA1093Q9UPQ95
Tripartite motif-containing protein 10 (B30-RING finger protein) (RING finger protein 9)TRIM10 RFB30 RNF9Q9UDY65
Tripartite motif-containing protein 26 (Acid finger protein) (AFP) (RING finger protein 95) (Zinc finger protein 173)TRIM26 RNF95 ZNF173Q128995
Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet)TRIM38 RNF15 RORETO006355
tRNA (guanine-N(7)-)-methyltransferase (EC 2.1.1.33) (Methyltransferase-like protein 1) (tRNA (guanine(46)-N(7))-methyltransferase) (tRNA(m7G46)-methyltransferase)METTL1 C12orf1Q9UBP65
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 (WD repeat-containing protein 4)WDR4P570815
tRNA-splicing endonuclease subunit Sen54 (SEN54 homolog) (HsSEN54) (tRNA-intron endonuclease Sen54)TSEN54 SEN54Q7Z6J95
Tryptase beta-2 (Tryptase-2) (EC 3.4.21.59) (Tryptase II)TPSB2 TPS2P202315
Tubulin alpha-3C/D chain (Alpha-tubulin 2) (Alpha-tubulin 3C/D) (Tubulin alpha-2 chain)TUBA3C TUBA2; TUBA3DQ137485
Tubulin alpha-4A chain (Alpha-tubulin 1) (Testis-specific alpha-tubulin) (Tubulin H2-alpha) (Tubulin alpha-1 chain)TUBA4A TUBA1P683665
Tubulin beta-3 chain (Tubulin beta-4 chain) (Tubulin beta-III)TUBB3 TUBB4Q135095
Tubulin gamma-2 chain (Gamma-2-tubulin)TUBG2Q9NRH35
Tubulin-specific chaperone E (Tubulin-folding cofactor E)TBCEQ158135
Tuftelin-interacting protein 11 (Septin and tuftelin-interacting protein 1) (STIP-1)TFIP11 STIP HSPC006Q9UBB95
Tumor protein p53-inducible nuclear protein 2 (Diabetes and obesity-regulated gene) (p53-inducible protein U) (PIG-U)TP53INP2 C20orf110 DOR PINHQ8IXH65
Twist-related protein 1 (Class A basic helix-loop-helix protein 38) (bHLHa38) (H-twist)TWIST1 BHLHA38 TWISTQ156725
Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)FER TYK3P165915
Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)TYRO3 BYK DTK RSE SKY TIFQ064185
Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase)ZAP70 SRKP434035
Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B)PTPN1 PTP1BP180315
Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP)PTPN2 PTPTP177065
Tyrosyl-DNA phosphodiesterase 2 (Tyr-DNA phosphodiesterase 2) (hTDP2) (EC 3.1.4.-) (5'-tyrosyl-DNA phosphodiesterase) (5'-Tyr-DNA phosphodiesterase) (ETS1-associated protein 2) (ETS1-associated protein II) (EAPII) (TRAF and TNF receptor-associated protein) (Tyrosyl-RNA phosphodiesterase) (VPg unlinkase)TDP2 EAP2 TTRAP AD-022O955515
U1 small nuclear ribonucleoprotein C (U1 snRNP C) (U1-C) (U1C)SNRPCP092345
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (Renal carcinoma antigen NY-REN-20) (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (U2AF35-related protein) (URP)ZRSR2 U2AF1-RS2 U2AF1L2 U2AF1RS2 URPQ156965
U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (hPrp3) (U4/U6 snRNP 90 kDa protein)PRPF3 HPRP3 PRP3O433955
U4/U6 small nuclear ribonucleoprotein Prp31 (Pre-mRNA-processing factor 31) (Serologically defined breast cancer antigen NY-BR-99) (U4/U6 snRNP 61 kDa protein) (Protein 61K) (hPrp31)PRPF31 PRP31Q8WWY35
U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog) (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K)USP39 CGI-21 HSPC332 PRO2855Q53GS95
Ubiquitin B (Ubiquitin B, isoform CRA_a)UBB hCG_1998947Q5U5U65
Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.4.19.12) (Deubiquitinating enzyme 16) (Ubiquitin thioesterase 16) (Ubiquitin-processing protease UBP-M) (Ubiquitin-specific-processing protease 16)USP16 MSTP039Q9Y5T55
Ubiquitin carboxyl-terminal hydrolase 17 (USP17) (EC 3.4.19.12) (Deubiquitinating enzyme 17-like protein 2) (Deubiquitinating protein 3) (DUB-3) (Ubiquitin carboxyl-terminal hydrolase 17-like protein 2) (Ubiquitin thioesterase 17-like protein 2) (Ubiquitin-specific-processing protease 17-like protein 2)USP17L2 DUB3 USP17 USP17H USP17I USP17J USP17K USP17L USP17MQ6R6M45
Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.4.19.12) (Deubiquitinating enzyme 28) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28)USP28 KIAA1515Q96RU25
Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.4.19.12) (Deubiquitinating enzyme 3) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3)USP3Q9Y6I45
Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1-associated protein 1) (Cerebral protein 6)BAP1 KIAA0272 hucep-6Q925605
Ubiquitin thioesterase otulin (EC 3.4.19.12) (Deubiquitinating enzyme otulin) (OTU domain-containing deubiquitinase with linear linkage specificity) (Ubiquitin thioesterase Gumby)FAM105BQ96BN85
Ubiquitin-60S ribosomal protein L40 (CEP52) (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; 60S ribosomal protein L40]UBA52 UBCEP2P629875
Ubiquitin-associated and SH3 domain-containing protein B (EC 3.1.3.48) (Cbl-interacting protein p70) (Suppressor of T-cell receptor signaling 1) (STS-1) (T-cell ubiquitin ligand 2) (TULA-2) (Tyrosine-protein phosphatase STS1/TULA2)UBASH3B KIAA1959 STS1Q8TF425
Ubiquitin-associated domain-containing protein 1 (UBA domain-containing protein 1) (E3 ubiquitin-protein ligase subunit KPC2) (Glialblastoma cell differentiation-related protein 1) (Kip1 ubiquitination-promoting complex protein 2)UBAC1 GBDR1 KPC2 UBADC1Q9BSL15
Ubiquitin-associated protein 2-like (Protein NICE-4)UBAP2L KIAA0144 NICE4Q141575
Ubiquitin-conjugating enzyme E2 C (EC 6.3.2.19) (UbcH10) (Ubiquitin carrier protein C) (Ubiquitin-protein ligase C)UBE2C UBCH10O007625
Ubiquitin-conjugating enzyme E2 H (EC 6.3.2.19) (UbcH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H)UBE2HP622565
Ubiquitin-fold modifier-conjugating enzyme 1 (Ufm1-conjugating enzyme 1)UFC1 CGI-126 HSPC155Q9Y3C85
Ubiquitin-like modifier-activating enzyme 5 (Ubiquitin-activating enzyme 5) (ThiFP1) (UFM1-activating enzyme) (Ubiquitin-activating enzyme E1 domain-containing protein 1)UBA5 UBE1DC1Q9GZZ95
Ubiquitin-like protein 4A (Ubiquitin-like protein GDX)UBL4A DXS254E GDX UBL4P114415
Ubiquitin-protein ligase E3B (EC 6.3.2.-)UBE3BQ7Z3V45
UBX domain-containing protein 6 (UBX domain-containing protein 1)UBXN6 UBXD1 UBXDC2Q9BZV15
UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH) (EC 1.1.1.22)UGDHO607015
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) (GlcNAc-1-P transferase) (G1PT) (GPT) (N-acetylglucosamine-1-phosphate transferase)DPAGT1 DPAGT2Q9H3H55
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT)OGTO152945
Uncharacterized methyltransferase WBSCR22 (EC 2.1.1.-) (Williams-Beuren syndrome chromosomal region 22 protein)WBSCR22 HUSSY-03 PP3381O437095
Uncharacterized protein C10orf35C10orf35Q96D055
Uncharacterized protein C11orf48C11orf48Q9BQE65
Uncharacterized protein C11orf74 (Protein HEPIS)C11orf74Q86VG35
Uncharacterized protein C12orf68C12orf68Q52MB25
Uncharacterized protein C16orf3C16orf3O951775
Uncharacterized protein C16orf45C16orf45Q96MC55
Uncharacterized protein C17orf104C17orf104A2RUB15
Uncharacterized protein C19orf44C19orf44Q9H6X55
Uncharacterized protein C19orf55C19orf55Q2NL685
Uncharacterized protein C1orf106C1orf106Q3KP665
Uncharacterized protein C1orf53C1orf53Q5VUE55
Uncharacterized protein C20orf141C20orf141Q9NUB45
Uncharacterized protein C7orf50C7orf50 FP15621Q9BRJ65
Uncharacterized protein C9orf142C9orf142Q9BUH65
Uncharacterized protein KIAA0195 (Transmembrane protein 94)KIAA0195 TMEM94Q127675
Uncharacterized protein KIAA0355KIAA0355O150635
Uncharacterized protein KIAA0556KIAA0556O603035
Uncharacterized protein KIAA1737KIAA1737Q9C0C65
Up-regulator of cell proliferation (HBV X protein up-regulated gene 4 protein) (HBxAg up-regulated gene 4 protein)URGCP KIAA1507 URG4Q8TCY95
UPF0454 protein C12orf49C12orf49Q9H7415
UPF0686 protein C11orf1C11orf1Q9H5F25
UPF0691 protein C9orf116 (p53-induced expression in RB-null cells protein 1) (Pierce1)C9orf116Q5BN465
Urokinase plasminogen activator preproprotein variant (Fragment)0Q59GZ85
V-set and immunoglobulin domain-containing protein 10VSIG10Q8N0Z95
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