EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Vacuolar fusion protein MON1 homolog B (HSV-1 stimulation-related gene 1 protein) (HSV-I stimulating-related protein)MON1B HSRG1 KIAA0872 SAND2Q7L1V25
Vacuolar protein sorting-associated protein VTA1 homolog (Dopamine-responsive gene 1 protein) (DRG-1) (LYST-interacting protein 5) (LIP5) (SKD1-binding protein 1) (SBP1)VTA1 C6orf55 HSPC228 My012Q9NP795
Vacuolar-sorting protein SNF8 (ELL-associated protein of 30 kDa) (ESCRT-II complex subunit VPS22) (hVps22)SNF8 EAP30Q96H205
Vascular endothelial growth factor B (VEGF-B) (VEGF-related factor) (VRF)VEGFB VRFP497655
Vascular non-inflammatory molecule 2 (Vanin-2) (EC 3.5.1.92) (Glycosylphosphatidyl inositol-anchored protein GPI-80) (Protein FOAP-4)VNN2O954985
Vasculin (GC-rich promoter-binding protein 1) (Vascular wall-linked protein)GPBP1 GPBP SSH6Q86WP25
Vasculin-like protein 1 (GC-rich promoter-binding protein 1-like 1)GPBP1L1 SP192Q9HC445
Vesicle-trafficking protein SEC22c (SEC22 vesicle-trafficking protein homolog C) (SEC22 vesicle-trafficking protein-like 3)SEC22C SEC22L3 UNQ459/PRO784Q9BRL75
Voltage-dependent calcium channel gamma-5 subunit (Neuronal voltage-gated calcium channel gamma-5 subunit) (Transmembrane AMPAR regulatory protein gamma-5) (TARP gamma-5)CACNG5Q9UF025
Von Hippel-Lindau disease tumor suppressor (Protein G7) (pVHL)VHLP403375
von Willebrand factor (vWF) [Cleaved into: von Willebrand antigen 2 (von Willebrand antigen II)]VWF F8VWFP042755
von Willebrand factor A domain-containing protein 7 (Protein G7c)VWA7 C6orf27 G7C NG37Q9Y3345
WAP four-disulfide core domain protein 8 (Putative protease inhibitor WAP8)WFDC8 C20orf170 WAP8Q8IUA05
WAS/WASL-interacting protein family member 2 (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein) (WIP-related protein)WIPF2 WICH WIRE PP10631Q8TF745
WASH complex subunit CCDC53 (Coiled-coil domain-containing protein 53)CCDC53 AD-016 CGI-116 x0009Q9Y3C05
WD repeat-containing protein 20 (Protein DMR)WDR20Q8TBZ35
WD repeat-containing protein 34WDR34Q96EX35
WD repeat-containing protein 48 (USP1-associated factor 1) (WD repeat endosomal protein) (p80)WDR48 KIAA1449 UAF1Q8TAF35
WD repeat-containing protein 61 (Meiotic recombination REC14 protein homolog) (SKI8 homolog) (Ski8)WDR61Q9GZS35
Williams-Beuren syndrome chromosomal region 16 protein (RCC1-like G exchanging factor-like protein)WBSCR16Q96I515
WW domain-binding protein 11 (WBP-11) (Npw38-binding protein) (NpwBP) (SH3 domain-binding protein SNP70) (Splicing factor that interacts with PQBP-1 and PP1)WBP11 NPWBP SIPP1 SNP70Q9Y2W25
WW domain-binding protein 2 (WBP-2)WBP2Q969T95
WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase)WWOX FOR WOX1Q9NZC75
Y-box-binding protein 2 (Contrin) (DNA-binding protein C) (Dbpc) (Germ cell-specific Y-box-binding protein) (MSY2 homolog)YBX2 CSDA3 MSY2Q9Y2T75
YTH domain family protein 1 (Dermatomyositis associated with cancer putative autoantigen 1) (DACA-1)YTHDF1 C20orf21Q9BYJ95
Zinc finger and BTB domain-containing protein 20 (Dendritic-derived BTB/POZ zinc finger protein) (Zinc finger protein 288)ZBTB20 DPZF ZNF288Q9HC785
Zinc finger and BTB domain-containing protein 38ZBTB38Q8NAP35
Zinc finger and BTB domain-containing protein 44 (BTB/POZ domain-containing protein 15) (Zinc finger protein 851)ZBTB44 BTBD15 ZNF851Q8NCP55
Zinc finger BED domain-containing protein 1 (Putative Ac-like transposable element) (dREF homolog)ZBED1 ALTE DREF KIAA0785 TRAMPO960065
Zinc finger C2HC domain-containing protein 1AZC2HC1A C8orf70 FAM164A CGI-62Q96GY05
Zinc finger CCCH domain-containing protein 11AZC3H11A KIAA0663 ZC3HDC11AO751525
Zinc finger CCCH domain-containing protein 13ZC3H13 KIAA0853Q5T2005
Zinc finger CCCH domain-containing protein 18 (Nuclear protein NHN1)ZC3H18 NHN1Q86VM95
Zinc finger CCCH domain-containing protein 3ZC3H3 KIAA0150 ZC3HDC3Q8IXZ25
Zinc finger CCCH domain-containing protein 7AZC3H7A ZC3H7 ZC3HDC7 HSPC055Q8IWR05
Zinc finger CCCH-type with G patch domain-containing protein (G patch domain-containing protein 6) (Zinc finger CCCH domain-containing protein 9) (Zinc finger and G patch domain-containing protein)ZGPAT GPATC6 GPATCH6 KIAA1847 ZC3H9 ZC3HDC9 ZIPQ8N5A55
Zinc finger CCHC domain-containing protein 10ZCCHC10Q8TBK65
Zinc finger protein 195ZNF195 ZNFP104O146285
Zinc finger protein 217ZNF217 ZABC1O753625
Zinc finger protein 226ZNF226Q9NYT65
Zinc finger protein 24 (Retinoic acid suppression protein A) (RSG-A) (Zinc finger and SCAN domain-containing protein 3) (Zinc finger protein 191) (Zinc finger protein KOX17)ZNF24 KOX17 ZNF191 ZSCAN3P170285
Zinc finger protein 253 (Bone marrow zinc finger 1) (BMZF-1) (Zinc finger protein 411)ZNF253 BMZF1 ZNF411O753465
Zinc finger protein 3 (Zinc finger protein HF.12) (Zinc finger protein HZF3.1) (Zinc finger protein KOX25)ZNF3 KOX25P170365
Zinc finger protein 317ZNF317 KIAA1588Q96PQ65
Zinc finger protein 36, C3H1 type-like 2 (ZFP36-like 2) (Butyrate response factor 2) (EGF-response factor 2) (ERF-2) (Protein TIS11D)ZFP36L2 BRF2 ERF2 RNF162C TIS11DP479745
Zinc finger protein 385A (Hematopoietic zinc finger protein) (Retinal zinc finger protein)ZNF385A HZF RZF ZNF385Q96PM95
Zinc finger protein 410 (Another partner for ARF 1) (Zinc finger protein APA-1)ZNF410 APA1Q86VK45
Zinc finger protein 564ZNF564Q8TBZ85
Zinc finger protein 581ZNF581 HSPC189Q9P0T45
Zinc finger protein 586ZNF586Q9NXT05
Zinc finger protein 672ZNF672Q499Z45
Zinc finger protein 682ZNF682O957805
Zinc finger protein 764ZNF764Q96H865
Zinc finger protein castor homolog 1 (Castor-related protein) (Putative survival-related protein) (Zinc finger protein 693)CASZ1 CST SRG ZNF693Q86V155
Zinc finger protein OZF (Only zinc finger protein) (Zinc finger protein 146)ZNF146 OZFQ150725
Zinc finger protein RFP (EC 6.3.2.-) (RING finger protein 76) (Ret finger protein) (Tripartite motif-containing protein 27)TRIM27 RFP RNF76P143735
Zinc finger protein SNAI2 (Neural crest transcription factor Slug) (Protein snail homolog 2)SNAI2 SLUG SLUGHO436235
Zinc finger protein ZFPM1 (Friend of GATA protein 1) (FOG-1) (Friend of GATA 1) (Zinc finger protein 89A) (Zinc finger protein multitype 1)ZFPM1 FOG1 ZFN89AQ8IX075
Zinc finger protein ZIC 5 (Zinc finger protein of the cerebellum 5)ZIC5Q96T255
Zinc finger protein ZPR1 (Zinc finger protein 259)ZNF259 ZPR1O753125
Zinc phosphodiesterase ELAC protein 2 (EC 3.1.26.11) (ElaC homolog protein 2) (Heredity prostate cancer protein 2) (Ribonuclease Z 2) (RNase Z 2) (tRNA 3 endonuclease 2) (tRNase Z 2)ELAC2 HPC2Q9BQ525
Zinc transporter 9 (ZnT-9) (Human embryonic lung protein) (HuEL) (Solute carrier family 30 member 9)SLC30A9 C4orf1 HUELQ6PML95
Zinc-binding alcohol dehydrogenase domain-containing protein 2 (EC 1.-.-.-)ZADH2Q8N4Q05
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (EC 2.3.1.51) (Abhydrolase domain-containing protein 5) (Lipid droplet-binding protein CGI-58)ABHD5 NCIE2 CGI-58Q8WTS14
1-aminocyclopropane-1-carboxylate synthase-like protein 1 (ACC synthase-like protein 1)ACCS PHACSQ96QU64
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-I) (PLC-I) (Phospholipase C-beta-1) (PLC-beta-1)PLCB1 KIAA0581Q9NQ664
14-3-3 protein eta (Protein AS1)YWHAH YWHA1Q049174
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (15-PGDH) (EC 1.1.1.141) (Prostaglandin dehydrogenase 1)HPGD PGDH1P154284
2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) (CNPase) (EC 3.1.4.37)CNPP095434
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial (EC 2.1.1.201) (Ubiquinone biosynthesis methyltransferase COQ5)COQ5Q5HYK34
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component beta chain) (BCKDE1B) (BCKDH E1-beta)BCKDHBP219534
26S proteasome non-ATPase regulatory subunit 3 (26S proteasome regulatory subunit RPN3) (26S proteasome regulatory subunit S3) (Proteasome subunit p58)PSMD3O432424
26S proteasome non-ATPase regulatory subunit 5 (26S protease subunit S5 basic) (26S proteasome subunit S5B)PSMD5 KIAA0072Q164014
28S ribosomal protein S7, mitochondrial (MRP-S7) (S7mt) (bMRP-27a) (bMRP27a)MRPS7Q9Y2R94
28S ribosomal protein S9, mitochondrial (MRP-S9) (S9mt)MRPS9 RPMS9P829334
3-ketodihydrosphingosine reductase (KDS reductase) (EC 1.1.1.102) (3-dehydrosphinganine reductase) (Follicular variant translocation protein 1) (FVT-1)KDSR FVT1Q061364
39S ribosomal protein L1, mitochondrial (L1mt) (MRP-L1)MRPL1 BM-022Q9BYD64
39S ribosomal protein L13, mitochondrial (L13mt) (MRP-L13)MRPL13Q9BYD14
39S ribosomal protein L15, mitochondrial (L15mt) (MRP-L15)MRPL15 HSPC145Q9P0154
39S ribosomal protein L17, mitochondrial (L17mt) (MRP-L17) (LYST-interacting protein 2)MRPL17 LIP2Q9NRX24
39S ribosomal protein L19, mitochondrial (L19mt) (MRP-L19) (39S ribosomal protein L15, mitochondrial) (L15mt) (MRP-L15)MRPL19 KIAA0104 MRPL15P494064
39S ribosomal protein L28, mitochondrial (L28mt) (MRP-L28) (Melanoma antigen p15) (Melanoma-associated antigen recognized by T-lymphocytes)MRPL28 MAAT1Q130844
39S ribosomal protein L38, mitochondrial (L38mt) (MRP-L38)MRPL38 HSPC262Q96DV44
39S ribosomal protein L4, mitochondrial (L4mt) (MRP-L4)MRPL4 CDABP0091 CGI-28Q9BYD34
39S ribosomal protein L45, mitochondrial (L45mt) (MRP-L45)MRPL45Q9BRJ24
39S ribosomal protein L47, mitochondrial (L47mt) (MRP-L47) (Nasopharyngeal carcinoma metastasis-related protein 1)MRPL47 NCM1 CGI-204Q9HD334
4-hydroxyphenylpyruvate dioxygenase-like protein (EC 1.13.-.-) (Glyoxalase domain-containing protein 1)HPDL GLOXD1Q96IR74
40S ribosomal protein S4, Y isoform 1RPS4Y1 RPS4Y PRO2646P220904
5'-nucleotidase (5'-NT) (EC 3.1.3.5) (Ecto-5'-nucleotidase) (CD antigen CD73)NT5E NT5 NTEP215894
5-aminolevulinate synthase, nonspecific, mitochondrial (ALAS-H) (EC 2.3.1.37) (5-aminolevulinic acid synthase 1) (Delta-ALA synthase 1) (Delta-aminolevulinate synthase 1)ALAS1 ALAS3 ALASH OK/SW-cl.121P131964
5-azacytidine-induced protein 1 (Centrosomal protein of 131 kDa) (Cep131) (Pre-acrosome localization protein 1)AZI1 CEP131 KIAA1118Q9UPN44
5-hydroxytryptamine receptor 1D (5-HT-1D) (5-HT1D) (Serotonin 1D alpha receptor) (5-HT-1D-alpha) (Serotonin receptor 1D)HTR1D HTR1DA HTRLP282214
5p152 (Estrogen nuclear receptor beta variant a) (Estrogen receptor 2 (ER beta), isoform CRA_a)NR3A2 ESR2 hCG_21449Q7LCB34
6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3, isoform CRA_b (6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase) (EC 3.1.3.46) (cDNA FLJ75111, highly similar to Homo sapiens 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3(PFKFB3), mRNA)PFKFB3 hCG_24831Q5VX184
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (6PF-2-K/Fru-2,6-P2ase 4) (PFK/FBPase 4) (6PF-2-K/Fru-2,6-P2ase testis-type isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]PFKFB4Q168774
60S ribosomal protein L26-like 1RPL26L1 RPL26P1Q9UNX34
60S ribosome subunit biogenesis protein NIP7 homolog (KD93)NIP7 CGI-37 HSPC031 HSPC180 OK/SW-cl.76 OK/SW-cl.78Q9Y2214
7-methylguanosine phosphate-specific 5'-nucleotidase (EC 3.1.3.-) (Cytosolic 5'-nucleotidase 3B) (Cytosolic 5'-nucleotidase III-like protein) (cN-III-like protein) (EC 3.1.3.5)NT5C3B NT5C3LQ969T74
8-oxo-dGDP phosphatase NUDT18 (EC 3.6.1.58) (2-hydroxy-dADP phosphatase) (7,8-dihydro-8-oxoguanine phosphatase) (MutT homolog 3) (Nucleoside diphosphate-linked moiety X motif 18) (Nudix motif 18)NUDT18 MTH3Q6ZVK84
A-kinase anchor protein 2 (AKAP-2) (AKAP-KL) (Protein kinase A-anchoring protein 2) (PRKA2)AKAP2 KIAA0920 PRKA2Q9Y2D54
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