EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
ATP-dependent RNA helicase DHX8 (EC 3.6.4.13) (DEAH box protein 8) (RNA helicase HRH1)DHX8 DDX8Q145624
ATPase ASNA1 (EC 3.6.-.-) (Arsenical pump-driving ATPase) (Arsenite-stimulated ATPase) (Transmembrane domain recognition complex 40 kDa ATPase subunit) (hARSA-I) (hASNA-I)ASNA1 ARSA TRC40O436814
ATPase family AAA domain-containing protein 3B (AAA-TOB3)ATAD3B KIAA1273 TOB3Q5T9A44
ATPase family AAA domain-containing protein 5 (Chromosome fragility-associated gene 1 protein)ATAD5 C17orf41 FRAG1Q96QE34
ATR-interacting protein (ATM and Rad3-related-interacting protein)ATRIP AGS1Q8WXE14
Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A)NPR1 ANPRAP160664
Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein)ATN1 D12S755E DRPLAP542594
ATXN7L2 proteinATXN7L2I6L9B54
Autophagy-related protein 13ATG13 KIAA0652O751434
Autophagy-related protein 9A (APG9-like 1) (mATG9)ATG9A APG9L1Q7Z3C64
Autophagy-related protein 9B (APG9-like 2) (Nitric oxide synthase 3-overlapping antisense gene protein) (Protein sONE)ATG9B APG9L2 NOS3ASQ674R74
Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein)NAIP BIRC1Q130754
Bardet-Biedl syndrome 4 proteinBBS4Q96RK44
Bardet-Biedl syndrome 5 proteinBBS5Q8N3I74
Bcl-2-interacting killer (Apoptosis inducer NBK) (BIP1) (BP4)BIK NBKQ133234
Beta-1 adrenergic receptor (Beta-1 adrenoreceptor) (Beta-1 adrenoceptor)ADRB1 ADRB1R B1ARP085884
Beta-1,3-N-acetylglucosaminyltransferase radical fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase)RFNGQ9Y6444
Beta-1,4-galactosyltransferase 1 (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (EC 2.4.1.-) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1) [Cleaved into: Processed beta-1,4-galactosyltransferase 1] [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthase); Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)]B4GALT1 GGTB2P152914
Beta-1,4-galactosyltransferase 3 (Beta-1,4-GalTase 3) (Beta4Gal-T3) (b4Gal-T3) (EC 2.4.1.-) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 3) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 3) [Includes: N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthase); Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)]B4GALT3O605124
Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor)ADRB2 ADRB2R B2ARP075504
Beta-adrenergic receptor kinase 1 (Beta-ARK-1) (EC 2.7.11.15) (G-protein coupled receptor kinase 2)ADRBK1 BARK BARK1 GRK2P250984
Beta-defensin 118 (Beta-defensin 18) (DEFB-18) (Defensin, beta 118) (Epididymal secretory protein 13.6) (ESP13.6)DEFB118 C20orf63 DEFB18 ESC42Q96PH64
Beta-galactoside alpha-2,6-sialyltransferase 1 (Alpha 2,6-ST 1) (EC 2.4.99.1) (B-cell antigen CD75) (CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1) (ST6Gal I) (ST6GalI) (Sialyltransferase 1)ST6GAL1 SIAT1P159074
Beta-hexosaminidase subunit beta (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit beta) (Hexosaminidase subunit B) (Cervical cancer proto-oncogene 7 protein) (HCC-7) (N-acetyl-beta-glucosaminidase subunit beta) [Cleaved into: Beta-hexosaminidase subunit beta chain B; Beta-hexosaminidase subunit beta chain A]HEXB HCC7P076864
Beta-sarcoglycan (Beta-SG) (43 kDa dystrophin-associated glycoprotein) (43DAG) (A3b)SGCBQ165854
Beta-secretase 2 (EC 3.4.23.45) (Aspartic-like protease 56 kDa) (Aspartyl protease 1) (ASP1) (Asp 1) (Beta-site amyloid precursor protein cleaving enzyme 2) (Beta-site APP cleaving enzyme 2) (Down region aspartic protease) (DRAP) (Memapsin-1) (Membrane-associated aspartic protease 1) (Theta-secretase)BACE2 AEPLC ALP56 ASP21 CDA13 UNQ418/PRO852Q9Y5Z04
Biogenesis of lysosome-related organelles complex 1 subunit 4 (BLOC-1 subunit 4) (Protein cappuccino homolog)BLOC1S4 CNOQ9NUP14
Bisphosphoglycerate mutase (BPGM) (EC 5.4.2.4) (2,3-bisphosphoglycerate mutase, erythrocyte) (2,3-bisphosphoglycerate synthase) (EC 3.1.3.13) (EC 5.4.2.11) (2,3-diphosphoglycerate mutase) (DPGM) (BPG-dependent PGAM)BPGMP077384
Brain-enriched guanylate kinase-associated proteinBEGAIN KIAA1446Q9BUH84
BRCA1-A complex subunit RAP80 (Receptor-associated protein 80) (Retinoid X receptor-interacting protein 110) (Ubiquitin interaction motif-containing protein 1)UIMC1 RAP80 RXRIP110Q96RL14
BRCA1-associated RING domain protein 1 (BARD-1) (EC 6.3.2.-)BARD1Q997284
Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (ADP-ribosylation factor guanine nucleotide-exchange factor 1) (p200 ARF guanine nucleotide exchange factor) (p200 ARF-GEP1)ARFGEF1 ARFGEP1 BIG1Q9Y6D64
Brevican core protein (Brain-enriched hyaluronan-binding protein) (BEHAB) (Chondroitin sulfate proteoglycan 7)BCAN BEHAB CSPG7 UNQ2525/PRO6018Q96GW74
BRI3-binding protein (I3-binding protein) (Cervical cancer 1 proto-oncogene-binding protein KG19) (HCCRBP-1)BRI3BP KG19Q8WY224
BRISC and BRCA1-A complex member 1 (Mediator of RAP80 interactions and targeting subunit of 40 kDa) (New component of the BRCA1-A complex)BABAM1 C19orf62 MERIT40 NBA1 HSPC142Q9NWV84
BRISC complex subunit Abro1 (Abraxas brother protein 1) (Protein FAM175B)FAM175B ABRO1 KIAA0157Q150184
Bromodomain and WD repeat-containing protein 3BRWD3Q6RI454
BTB/POZ domain-containing protein 1 (Hepatitis C virus NS5A-transactivated protein 8) (HCV NS5A-transactivated protein 8)BTBD1 C15orf1 NS5ATP8Q9H0C54
BTB/POZ domain-containing protein 3BTBD3 KIAA0952Q9Y2F94
BTB/POZ domain-containing protein 6 (Lens BTB domain protein)BTBD6 BDPLQ96KE94
BTB/POZ domain-containing protein KCTD3 (Renal carcinoma antigen NY-REN-45)KCTD3Q9Y5974
Butyrophilin subfamily 3 member A2BTN3A2 BT3.2 BTF3 BTF4P784104
Butyrophilin-like protein 3 (Butyrophilin-like receptor)BTNL3 BTNLR COLF4100 UNQ744/PRO1472Q6UXE84
C-C motif chemokine 3 (G0/G1 switch regulatory protein 19-1) (Macrophage inflammatory protein 1-alpha) (MIP-1-alpha) (PAT 464.1) (SIS-beta) (Small-inducible cytokine A3) (Tonsillar lymphocyte LD78 alpha protein) [Cleaved into: MIP-1-alpha(4-69) (LD78-alpha(4-69))]CCL3 G0S19-1 MIP1A SCYA3P101474
C-Jun-amino-terminal kinase-interacting protein 2 (JIP-2) (JNK-interacting protein 2) (Islet-brain-2) (IB-2) (JNK MAP kinase scaffold protein 2) (Mitogen-activated protein kinase 8-interacting protein 2)MAPK8IP2 IB2 JIP2 PRKM8IPLQ133874
C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3)MAPK8IP3 JIP3 KIAA1066Q9UPT64
C-type lectin domain family 18 member A (Mannose receptor-like protein 2)CLEC18A MRLP2A5D8T84
C-type lectin domain family 4 member K (Langerin) (CD antigen CD207)CD207 CLEC4KQ9UJ714
Cadherin-2 (CDw325) (Neural cadherin) (N-cadherin) (CD antigen CD325)CDH2 CDHN NCADP190224
Calbindin (Calbindin D28) (D-28K) (Vitamin D-dependent calcium-binding protein, avian-type)CALB1 CAB27P059374
Calcineurin B homologous protein 3 (Tescalcin) (TSC)TESC CHP3Q96BS24
Calcineurin subunit B type 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1)PPP3R1 CNA2 CNBP630984
Calcium uptake protein 1, mitochondrial (Atopy-related autoantigen CALC) (ara CALC) (Calcium-binding atopy-related autoantigen 1) (allergen Hom s 4)MICU1 CALC CBARA1Q9BPX64
Calcium-binding protein 2 (CaBP2)CABP2Q9NPB34
Calmodulin-lysine N-methyltransferase (CLNMT) (CaM KMT) (EC 2.1.1.60)CAMKMT C2orf34 CLNMTQ7Z6244
Calmodulin-regulated spectrin-associated protein 2 (Calmodulin-regulated spectrin-associated protein 1-like protein 1)CAMSAP2 CAMSAP1L1 KIAA1078Q08AD14
Calpain-10 (EC 3.4.22.-) (Calcium-activated neutral proteinase 10) (CANP 10)CAPN10 KIAA1845Q9HC964
Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (New calpain 4) (nCL-4) (Protein CG36)CAPN9 NCL4O148154
Calponin-1 (Basic calponin) (Calponin H1, smooth muscle)CNN1P519114
Calsenilin (A-type potassium channel modulatory protein 3) (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (KChIP3)KCNIP3 CSEN DREAM KCHIP3Q9Y2W74
cAMP-dependent protein kinase inhibitor gamma (PKI-gamma)PKIGQ9Y2B94
cAMP-specific 3',5'-cyclic phosphodiesterase 4C (EC 3.1.4.17) (DPDE1) (PDE21)PDE4C DPDE1Q084934
Cancer/testis antigen family 45 member A4/A6 (Cancer/testis antigen 45-4/6) (Cancer/testis antigen 45A4/45A6)CT45A4 CT45-4; CT45A6 CT45-6Q8N7B74
CAPZB protein (Fragment)CAPZBQ7L4N04
Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase IX) (CA-IX) (CAIX) (Membrane antigen MN) (P54/58N) (Renal cell carcinoma-associated antigen G250) (RCC-associated antigen G250) (pMW1)CA9 G250 MNQ167904
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C-terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein)NOS1AP CAPON KIAA0464O750524
Carboxypeptidase Z (CPZ) (EC 3.4.17.-)CPZQ66K794
Carnitine O-palmitoyltransferase 1, muscle isoform (CPT1-M) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, muscle isoform) (CPT I) (CPTI-M) (Carnitine palmitoyltransferase 1B) (Carnitine palmitoyltransferase I-like protein)CPT1B KIAA1670Q925234
Caskin-1 (CASK-interacting protein 1)CASKIN1 KIAA1306Q8WXD94
Caskin-2 (CASK-interacting protein 2)CASKIN2 KIAA1139Q8WXE04
Caspase-1 (CASP-1) (EC 3.4.22.36) (Interleukin-1 beta convertase) (IL-1BC) (Interleukin-1 beta-converting enzyme) (ICE) (IL-1 beta-converting enzyme) (p45) [Cleaved into: Caspase-1 subunit p20; Caspase-1 subunit p10]CASP1 IL1BC IL1BCEP294664
Cation transport regulator-like protein 1 (Blocks Notch protein) (Botch)CHAC1 BOTCHQ9BUX14
CCA tRNA nucleotidyltransferase 1, mitochondrial (EC 2.7.7.72) (Mitochondrial tRNA nucleotidyl transferase, CCA-adding) (mt CCA-adding enzyme) (mt tRNA CCA-diphosphorylase) (mt tRNA CCA-pyrophosphorylase) (mt tRNA adenylyltransferase)TRNT1 CGI-47Q96Q114
CCAAT/enhancer-binding protein delta (C/EBP delta) (Nuclear factor NF-IL6-beta) (NF-IL6-beta)CEBPDP497164
CCAAT/enhancer-binding protein gamma (C/EBP gamma)CEBPGP535674
CCR4-NOT transcription complex subunit 11CNOT11 C2orf29 C40Q9UKZ14
CCR4-NOT transcription complex subunit 8 (EC 3.1.13.4) (CAF1-like protein) (CALIFp) (CAF2) (CCR4-associated factor 8) (Caf1b)CNOT8 CALIF POP2Q9UFF94
CD276 antigen (4Ig-B7-H3) (B7 homolog 3) (B7-H3) (Costimulatory molecule) (CD antigen CD276)CD276 B7H3 PSEC0249 UNQ309/PRO352Q5ZPR34
CDC2 proteinCDC2I6L9I54
CDGSH iron-sulfur domain-containing protein 2 (Endoplasmic reticulum intermembrane small protein) (MitoNEET-related 1 protein) (Miner1) (Nutrient-deprivation autophagy factor-1) (NAF-1)CISD2 CDGSH2 ERIS ZCD2Q8N5K14
CDKN1B protein (Cyclin-dependent kinase inhibitor 1B) (Cyclin-dependent kinase inhibitor 1B (P27, Kip1), isoform CRA_a) (cDNA, FLJ92816, Homo sapiens cyclin-dependent kinase inhibitor 1B (p27, Kip1)(CDKN1B), mRNA)CDKN1B hCG_27692Q6I9V64
cDNA FLJ14140 fis, clone MAMMA1002858, highly similar to Butyrate response factor 10B3KNA84
cDNA FLJ16549 fis, clone PLACE7003657, highly similar to RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1)0B3KVH44
cDNA FLJ31267 fis, clone KIDNE2006053, highly similar to Glycosyltransferase-like protein LARGE2 (EC 2.4.-.-)0B3KP694
cDNA FLJ34156 fis, clone FCBBF3013266, highly similar to Tsukushi (Leucine-richrepeat-containing protein 54)0B3KRF94
cDNA FLJ35133 fis, clone PLACE6009008, highly similar to Inosine-5'-monophosphate dehydrogenase 1 (EC1.1.1.205)0B3KRZ34
cDNA FLJ35213 fis, clone PROST1000215, highly similar to Vacuolar protein sorting protein 530B3KS064
cDNA FLJ36570 fis, clone TRACH2011302, highly similar to SELENIDE,WATER DIKINASE 2 (EC 2.7.9.3)0Q8N9T34
cDNA FLJ39996 fis, clone STOMA2002166, highly similar to Splicing factor 3B subunit 40B3KUJ04
cDNA FLJ41337 fis, clone BRAMY3000254, highly similar to Liprin-alpha-1 (cDNA FLJ42630 fis, clone BRACE3019084, highly similar to Liprin-alpha-1)0B3KVS84
cDNA FLJ44753 fis, clone BRACE3030538, weakly similar to Homo sapiens tumor suppressor 101F6 (101F6) (cDNA FLJ45666 fis, clone CTONG3001605, weakly similar to Homo sapiens tumor suppressor 101F6 (101F6))0Q6ZQS14
cDNA FLJ46554 fis, clone THYMU30389700Q6ZR874
cDNA FLJ60271, highly similar to SLIT-ROBO Rho GTPase-activating protein 20B7Z3G44
cDNA FLJ77001, highly similar to Homo sapiens ring finger protein 126 (RNF126), transcript variant 2, mRNA0A8K0Q14
CDW4/GRWD1 (Glutamate-rich WD repeat containing 1)GRWD1 hCG_15273A0MNN54
Cell death activator CIDE-B (Cell death-inducing DFFA-like effector B)CIDEBQ9UHD44
Cell division cycle-associated protein 2 (Recruits PP1 onto mitotic chromatin at anaphase protein) (Repo-Man)CDCA2Q69YH54
Cell growth regulator with RING finger domain protein 1 (Cell growth regulatory gene 19 protein) (RING finger protein 197)CGRRF1 CGR19 RNF197Q996754
Cellular retinoic acid binding protein 1 (Cellular retinoic acid-binding protein 1)CRABP1 hCG_38931F1T0F74
CENPB DNA-binding domain-containing protein 1CENPBD1B2RD014
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